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Experiment set5IT049 for
Methanococcus maripaludis S2
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Formate McCas no stress control 2
200 most detrimental genes:
gene
name
fitness
t score
description
MMP
_RS01370
+1.1
9.0
acetate--CoA ligase family protein
compare
MMP
_RS07820
+0.9
3.8
UPF0104 family protein
compare
MMP
_RS01960
+0.8
0.9
hypothetical protein
compare
MMP
_RS06155
+0.8
1.9
DUF4186 domain-containing protein
compare
MMP
_RS00450
+0.7
1.3
4Fe-4S binding protein
compare
MMP
_RS07125
+0.6
4.2
coenzyme F420-reducing hydrogenase FrhD protein
compare
MMP
_RS04520
+0.6
2.3
nucleoside deaminase
compare
MMP
_RS01775
+0.6
1.7
TIGR00297 family protein
compare
MMP
_RS01420
+0.6
2.2
hypothetical protein
compare
MMP
_RS07115
+0.6
3.8
MBL fold metallo-hydrolase
compare
MMP
_RS06600
+0.6
1.3
class III signal peptide-containing protein
compare
MMP
_RS01925
+0.6
3.2
DUF1616 domain-containing protein
compare
MMP
_RS05535
+0.6
2.6
hypothetical protein
compare
MMP
_RS05640
+0.5
3.1
UTP--glucose-1-phosphate uridylyltransferase GalU
compare
MMP
_RS01525
+0.5
1.8
nucleoside-diphosphate kinase
compare
MMP
_RS01945
+0.5
2.9
DUF4350 domain-containing protein
compare
MMP
_RS02175
+0.5
0.9
DUF1611 domain-containing protein
compare
MMP
_RS04720
+0.5
0.8
DedA family protein
compare
MMP
_RS06840
+0.5
1.1
DNA-directed RNA polymerase subunit N
compare
MMP
_RS02475
+0.5
1.7
hypothetical protein
compare
MMP
_RS08660
+0.5
2.7
DHH family phosphoesterase
compare
MMP
_RS08275
+0.5
4.1
hypothetical protein
compare
MMP
_RS06670
+0.5
1.7
glucose-6-phosphate isomerase
compare
MMP
_RS03215
+0.4
3.5
MBL fold metallo-hydrolase
compare
MMP
_RS06325
+0.4
1.4
hypothetical protein
compare
MMP
_RS06540
+0.4
2.3
3-methyl-2-oxobutanoate dehydrogenase subunit VorB
compare
MMP
_RS07135
+0.4
3.2
coenzyme F420 hydrogenase subunit beta
compare
MMP
_RS07120
+0.4
3.4
coenzyme F420 hydrogenase subunit alpha
compare
MMP
_RS07130
+0.4
3.1
coenzyme F420 hydrogenase subunit gamma
compare
MMP
_RS06575
+0.4
2.1
fluoride efflux transporter CrcB
compare
MMP
_RS07355
+0.4
0.8
transcription factor S
compare
MMP
_RS08930
+0.4
1.4
hypothetical protein
compare
MMP
_RS06535
+0.4
2.5
2-oxoacid:acceptor oxidoreductase family protein
compare
MMP
_RS01955
+0.4
1.0
hypothetical protein
compare
MMP
_RS08315
+0.4
1.7
S-methyl-5-thioribose-1-phosphate isomerase
compare
MMP
_RS01885
+0.4
2.8
Gfo/Idh/MocA family oxidoreductase
compare
MMP
_RS06290
+0.4
1.7
DNA repair and recombination protein RadA
compare
MMP
_RS08775
+0.4
2.6
methanogenesis marker 9 domain-containing protein
compare
MMP
_RS07075
+0.4
1.2
phosphomannomutase/phosphoglucomutase
compare
MMP
_RS03320
+0.4
1.3
metal-dependent transcriptional regulator
compare
MMP
_RS08215
+0.4
1.9
DUF483 domain-containing protein
compare
MMP
_RS00530
+0.4
2.7
tRNA pseudouridine(54/55) synthase Pus10
compare
MMP
_RS06570
+0.4
1.9
DUF190 domain-containing protein
compare
MMP
_RS07415
+0.4
2.6
molybdopterin-guanine dinucleotide biosynthesis protein MobB
compare
MMP
_RS01465
+0.4
2.3
hypothetical protein
compare
MMP
_RS06550
+0.4
2.6
AMP-binding protein
compare
MMP
_RS00130
+0.4
0.8
nickel-responsive transcriptional regulator NikR
compare
MMP
_RS00900
+0.4
0.7
50S ribosomal protein L39e
compare
MMP
_RS06530
+0.4
2.4
bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
compare
MMP
_RS07345
+0.4
2.3
glycine synthesis protein GlyXL
(from data)
compare
MMP
_RS05940
+0.3
2.6
corrinoid protein
compare
MMP
_RS01650
+0.3
0.7
sulfurtransferase TusA family protein
compare
MMP
_RS04035
+0.3
1.5
hypothetical protein
compare
MMP
_RS03465
+0.3
0.8
adenine phosphoribosyltransferase
compare
MMP
_RS09035
+0.3
1.1
hypothetical protein
compare
MMP
_RS00825
+0.3
1.1
fumarylacetoacetate hydrolase family protein
compare
MMP
_RS01540
+0.3
1.5
DUF504 domain-containing protein
compare
MMP
_RS03800
+0.3
1.4
hypothetical protein
compare
MMP
_RS01930
+0.3
2.5
hypothetical protein
compare
MMP
_RS06545
+0.3
1.6
ferredoxin family protein
compare
MMP
_RS08580
+0.3
0.8
flagellin
compare
MMP
_RS01935
+0.3
2.3
DUF58 domain-containing protein
compare
MMP
_RS01415
+0.3
1.4
DUF2067 domain-containing protein
compare
MMP
_RS07860
+0.3
0.4
hypothetical protein
compare
MMP
_RS03535
+0.3
1.5
helix-turn-helix transcriptional regulator
compare
MMP
_RS04265
+0.3
1.6
coenzyme F420-reducing hydrogenase FrhD protein
compare
MMP
_RS02290
+0.3
2.0
MBL fold metallo-hydrolase
compare
MMP
_RS00565
+0.3
1.0
CBS domain-containing protein
compare
MMP
_RS04740
+0.3
1.8
DUF473 domain-containing protein
compare
MMP
_RS05970
+0.3
1.2
class II SORL domain-containing protein
compare
MMP
_RS07330
+0.3
2.3
membrane protein
compare
MMP
_RS08980
+0.3
1.5
hypothetical protein
compare
MMP
_RS02470
+0.3
0.7
helix-turn-helix transcriptional regulator
compare
MMP
_RS06770
+0.3
1.8
DHH family phosphoesterase
compare
MMP
_RS07850
+0.3
0.7
prephenate dehydratase
compare
MMP
_RS01900
+0.3
2.0
hypothetical protein
compare
MMP
_RS02085
+0.3
1.8
inosine/xanthosine triphosphatase
compare
MMP
_RS08595
+0.2
0.4
flagellar protein C
compare
MMP
_RS04790
+0.2
1.9
4-hydroxy-tetrahydrodipicolinate reductase
compare
MMP
_RS07095
+0.2
1.0
PspC domain-containing protein
compare
MMP
_RS03405
+0.2
1.7
RNA 3'-terminal phosphate cyclase
compare
MMP
_RS06555
+0.2
1.3
cupin domain-containing protein
compare
MMP
_RS02255
+0.2
1.5
hypothetical protein
compare
MMP
_RS07915
+0.2
1.4
DUF4870 domain-containing protein
compare
MMP
_RS06310
+0.2
1.0
NAD(P)/FAD-dependent oxidoreductase
compare
MMP
_RS03820
+0.2
1.3
EamA family transporter
compare
MMP
_RS02455
+0.2
1.5
hypothetical protein
compare
MMP
_RS01950
+0.2
1.8
hypothetical protein
compare
MMP
_RS03115
+0.2
2.0
hypothetical protein
compare
MMP
_RS08705
+0.2
1.4
sulfopyruvate decarboxylase subunit beta
compare
MMP
_RS05580
+0.2
2.0
glycosyltransferase
compare
MMP
_RS01975
+0.2
1.9
hypothetical protein
compare
MMP
_RS00535
+0.2
1.2
TIGR00375 family protein
compare
MMP
_RS00145
+0.2
1.6
ATP-dependent Clp protease proteolytic subunit
compare
MMP
_RS00185
+0.2
2.0
potassium channel protein
compare
MMP
_RS08615
+0.2
0.6
flagellar protein G
compare
MMP
_RS08350
+0.2
0.4
hypothetical protein
compare
MMP
_RS09050
+0.2
1.0
CAP domain-containing protein
compare
MMP
_RS04985
+0.2
0.8
DUF2180 family protein
compare
MMP
_RS05665
+0.2
1.1
phosphate ABC transporter permease subunit PstC
compare
MMP
_RS04090
+0.2
0.7
hypothetical protein
compare
MMP
_RS01110
+0.2
1.1
FmdE family protein
compare
MMP
_RS00055
+0.2
1.7
DUF2254 domain-containing protein
compare
MMP
_RS03910
+0.2
0.6
hypothetical protein
compare
MMP
_RS08855
+0.2
1.4
hypothetical protein
compare
MMP
_RS03390
+0.2
1.1
malate dehydrogenase
compare
MMP
_RS01905
+0.2
1.5
glycosyltransferase
compare
MMP
_RS07410
+0.2
1.6
4-demethylwyosine synthase TYW1
compare
MMP
_RS06445
+0.2
1.5
DUF89 domain-containing protein
compare
MMP
_RS05990
+0.2
1.2
DsrE family protein
compare
MMP
_RS03420
+0.2
0.5
acetolactate synthase small subunit
compare
MMP
_RS09055
+0.2
0.4
CAP domain-containing protein
compare
MMP
_RS07725
+0.2
1.3
4Fe-4S dicluster domain-containing protein
compare
MMP
_RS06735
+0.2
1.2
class I SAM-dependent rRNA methyltransferase
compare
MMP
_RS08860
+0.2
1.4
MinD/ParA family protein
compare
MMP
_RS02495
+0.2
1.0
hypothetical protein
compare
MMP
_RS08555
+0.2
0.9
hypothetical protein
compare
MMP
_RS06130
+0.2
0.8
peptidylprolyl isomerase
compare
MMP
_RS03965
+0.2
0.8
hypothetical protein
compare
MMP
_RS07800
+0.2
1.3
ATP-binding cassette domain-containing protein
compare
MMP
_RS08845
+0.2
1.5
archaellum operon transcriptional activator EarA family protein
compare
MMP
_RS01185
+0.2
1.3
hypothetical protein
compare
MMP
_RS03790
+0.2
1.6
hypothetical protein
compare
MMP
_RS02360
+0.2
1.4
hypothetical protein
compare
MMP
_RS00635
+0.2
1.2
energy-coupling factor transporter transmembrane protein EcfT
compare
MMP
_RS01895
+0.2
1.5
flippase
compare
MMP
_RS05910
+0.2
0.6
cell division ATPase MinD
compare
MMP
_RS02480
+0.2
0.7
hypothetical protein
compare
MMP
_RS06140
+0.2
0.8
radical SAM protein
compare
MMP
_RS08975
+0.2
1.5
hypothetical protein
compare
MMP
_RS01455
+0.2
1.6
nickel pincer cofactor biosynthesis protein LarC
compare
MMP
_RS03340
+0.2
0.3
ABC transporter ATP-binding protein
compare
MMP
_RS08470
+0.2
1.1
ATP-binding cassette domain-containing protein
compare
MMP
_RS00930
+0.2
1.2
ABC transporter permease
compare
MMP
_RS04000
+0.2
1.5
NAD(P)/FAD-dependent oxidoreductase
compare
MMP
_RS08310
+0.2
0.7
TMEM165/GDT1 family protein
compare
MMP
_RS06970
+0.2
1.2
ribosomal protein S18-alanine N-acetyltransferase
compare
MMP
_RS05235
+0.2
1.2
exodeoxyribonuclease III
compare
MMP
_RS05660
+0.2
1.2
phosphate ABC transporter substrate-binding protein
compare
MMP
_RS01575
+0.2
1.3
aldolase
compare
MMP
_RS06460
+0.2
0.9
pyrimidine dimer DNA glycosylase/endonuclease V
compare
MMP
_RS08640
+0.2
1.4
TIM barrel protein
compare
MMP
_RS03785
+0.2
1.0
cupin domain-containing protein
compare
MMP
_RS05180
+0.2
1.2
Nre family DNA repair protein
compare
MMP
_RS07680
+0.2
1.0
DUF366 family protein
compare
MMP
_RS07550
+0.2
1.3
L-serine ammonia-lyase iron-sulfur-dependent subunit alpha
compare
MMP
_RS05355
+0.2
0.3
hypothetical protein
compare
MMP
_RS07155
+0.2
1.2
MFS transporter
compare
MMP
_RS08410
+0.2
0.7
DUF169 domain-containing protein
compare
MMP
_RS06965
+0.2
1.1
TIGR04014 family B12-binding domain/radical SAM domain-containing protein
compare
MMP
_RS06745
+0.2
0.9
DUF2119 domain-containing protein
compare
MMP
_RS01875
+0.2
1.1
N-acetyltransferase
compare
MMP
_RS03840
+0.2
0.9
hypothetical protein
compare
MMP
_RS02310
+0.2
0.5
RimK-like ATPgrasp N-terminal domain-containing protein
compare
MMP
_RS00940
+0.2
1.1
daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein
compare
MMP
_RS00660
+0.2
1.3
alkaline phosphatase family protein
compare
MMP
_RS03110
+0.2
0.8
glycosyltransferase family 2 protein
compare
MMP
_RS03275
+0.2
0.9
TIGR00266 family protein
compare
MMP
_RS05170
+0.2
0.9
lysine exporter LysO family protein
compare
MMP
_RS03675
+0.1
1.2
RimK family alpha-L-glutamate ligase
compare
MMP
_RS02765
+0.1
0.9
ABC transporter ATP-binding protein
compare
MMP
_RS08455
+0.1
1.0
multiprotein bridging factor aMBF1
compare
MMP
_RS07895
+0.1
0.8
cytochrome c
compare
MMP
_RS02545
+0.1
1.1
hypothetical protein
compare
MMP
_RS07970
+0.1
0.8
hypothetical protein
compare
MMP
_RS05695
+0.1
0.9
phospholipase D-like domain-containing protein
compare
MMP
_RS04020
+0.1
0.8
hypothetical protein
compare
MMP
_RS01940
+0.1
0.5
MoxR family ATPase
compare
MMP
_RS08835
+0.1
1.1
H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein
compare
MMP
_RS06490
+0.1
0.8
hypothetical protein
compare
MMP
_RS06165
+0.1
1.2
ABC transporter permease
compare
MMP
_RS06090
+0.1
1.0
iron ABC transporter permease
compare
MMP
_RS06665
+0.1
1.1
glycogen/starch synthase
compare
MMP
_RS03325
+0.1
1.1
hypothetical protein
compare
MMP
_RS04310
+0.1
0.6
hypothetical protein
compare
MMP
_RS01770
+0.1
1.0
ATP-dependent endonuclease
compare
MMP
_RS08625
+0.1
1.0
type II/IV secretion system ATPase subunit
compare
MMP
_RS05975
+0.1
0.4
hypothetical protein
compare
MMP
_RS01270
+0.1
1.1
prepilin peptidase
compare
MMP
_RS02915
+0.1
0.7
amino acid ABC transporter permease
compare
MMP
_RS01140
+0.1
0.6
molybdate ABC transporter permease subunit
compare
MMP
_RS08430
+0.1
0.5
HAD family hydrolase
compare
MMP
_RS02260
+0.1
1.1
lactate utilization protein
compare
MMP
_RS02565
+0.1
1.0
hypothetical protein
compare
MMP
_RS03545
+0.1
0.9
ATP-binding protein
compare
MMP
_RS00710
+0.1
0.7
hypothetical protein
compare
MMP
_RS04730
+0.1
1.1
flavodoxin family protein
compare
MMP
_RS06085
+0.1
1.1
iron ABC transporter substrate-binding protein
compare
MMP
_RS08620
+0.1
0.9
flagellar accessory protein FlaH
compare
MMP
_RS08245
+0.1
0.8
DUF4013 domain-containing protein
compare
MMP
_RS08485
+0.1
0.9
tungstate ABC transporter substrate-binding protein WtpA
compare
MMP
_RS03245
+0.1
0.7
DNA repair and recombination protein RadB
compare
MMP
_RS05820
+0.1
0.9
RNA-binding transcriptional accessory protein
compare
MMP
_RS06275
+0.1
0.9
ATP-dependent DNA helicase
compare
MMP
_RS07925
+0.1
0.5
haloacid dehalogenase
compare
MMP
_RS00545
+0.1
0.9
XRE family transcriptional regulator
compare
MMP
_RS00850
+0.1
0.6
TIGR01177 family methyltransferase
compare
MMP
_RS03990
+0.1
0.8
recombinase family protein
compare
MMP
_RS07805
+0.1
1.0
ABC transporter permease
compare
MMP
_RS05715
+0.1
0.6
hypothetical protein
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis S2 in stress experiments