Experiment set5IT049 for Klebsiella michiganensis M5al

Compare to:

Sodium succinate dibasic hexahydrate carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS04160 -8.6 -5.9 phosphoserine phosphatase compare
BWI76_RS20355 -8.3 -5.0 colicin V production protein compare
BWI76_RS18950 -7.8 -5.3 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS00850 -7.7 -9.1 acetylglutamate kinase compare
BWI76_RS18940 -7.6 -5.3 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS09755 -7.6 -5.2 phosphoserine transaminase compare
BWI76_RS18925 -7.0 -6.8 histidinol dehydrogenase compare
BWI76_RS20895 -7.0 -4.8 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS04245 -6.9 -9.5 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS18920 -6.9 -4.7 ATP phosphoribosyltransferase compare
BWI76_RS04465 -6.7 -4.6 carbamoyl-phosphate synthase small subunit compare
BWI76_RS05835 -6.4 -4.3 gamma-glutamyl-phosphate reductase compare
BWI76_RS18930 -6.3 -3.2 histidinol-phosphate transaminase compare
BWI76_RS00855 -6.2 -7.4 argininosuccinate lyase compare
BWI76_RS26460 -6.2 -6.0 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS01615 -6.1 -11.8 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS18935 -6.1 -7.0 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS04670 -6.0 -10.1 3-isopropylmalate dehydratase large subunit compare
BWI76_RS01655 -6.0 -6.6 homoserine O-succinyltransferase compare
BWI76_RS00980 -6.0 -10.1 PLP-dependent threonine dehydratase compare
BWI76_RS23920 -5.9 -5.7 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS23360 -5.9 -3.8 diaminopimelate decarboxylase compare
BWI76_RS07070 -5.8 -5.7 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS00990 -5.8 -8.5 ketol-acid reductoisomerase compare
BWI76_RS11855 -5.8 -7.6 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS04250 -5.7 -7.4 homoserine kinase compare
BWI76_RS10990 -5.7 -3.1 dihydroorotase compare
BWI76_RS23220 -5.6 -9.4 amino-acid N-acetyltransferase compare
BWI76_RS04685 -5.6 -10.1 putative leucine operon leader peptide compare
BWI76_RS04680 -5.6 -11.9 2-isopropylmalate synthase compare
BWI76_RS21265 -5.6 -13.7 phosphoribosylformylglycinamidine synthase compare
BWI76_RS26085 -5.5 -3.3 3-dehydroquinate synthase compare
BWI76_RS01210 -5.5 -4.0 tyrosine recombinase XerC compare
BWI76_RS04675 -5.4 -6.0 3-isopropylmalate dehydrogenase compare
BWI76_RS04255 -5.4 -10.3 threonine synthase compare
BWI76_RS01610 -5.3 -5.8 phosphoribosylamine--glycine ligase compare
BWI76_RS05840 -5.3 -6.2 glutamate 5-kinase compare
BWI76_RS21475 -5.3 -5.3 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS03080 -5.2 -3.6 (Fe-S)-cluster assembly protein compare
BWI76_RS20155 -5.2 -3.0 NADH-quinone oxidoreductase subunit I compare
BWI76_RS09645 -5.1 -1.8 thioredoxin-disulfide reductase compare
BWI76_RS20965 -5.1 -4.1 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS04665 -5.1 -16.3 3-isopropylmalate dehydratase small subunit compare
BWI76_RS04705 -5.1 -7.7 DNA-binding transcriptional regulator FruR compare
BWI76_RS02995 -5.1 -6.8 aspartate carbamoyltransferase compare
BWI76_RS00805 -5.0 -4.9 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS09760 -5.0 -5.8 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS25420 -4.9 -8.6 malate dehydrogenase compare
BWI76_RS04645 -4.9 -4.7 3-dehydroquinase compare
BWI76_RS08405 -4.9 -4.7 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS04470 -4.8 -8.2 carbamoyl phosphate synthase large subunit compare
BWI76_RS00965 -4.8 -1.7 acetolactate synthase 2 small subunit compare
BWI76_RS11850 -4.7 -8.4 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS20350 -4.6 -6.7 amidophosphoribosyltransferase compare
BWI76_RS23830 -4.6 -7.2 hypothetical protein compare
BWI76_RS11840 -4.6 -5.2 tryptophan synthase subunit alpha compare
BWI76_RS25115 -4.5 -6.1 argininosuccinate synthase compare
BWI76_RS00785 -4.5 -7.5 cystathionine gamma-synthase compare
BWI76_RS00845 -4.5 -7.6 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS02815 -4.4 -3.6 fructose-bisphosphatase class I compare
BWI76_RS26455 -4.3 -3.7 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS04240 -4.3 -1.8 thr operon leader peptide compare
BWI76_RS22240 -4.3 -5.7 transcriptional regulator compare
BWI76_RS09910 -4.2 -15.2 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS27385 -4.2 -6.7 orotate phosphoribosyltransferase compare
BWI76_RS11860 -4.2 -7.1 anthranilate synthase component I compare
BWI76_RS00975 -4.2 -6.3 dihydroxy-acid dehydratase compare
BWI76_RS24900 -4.2 -2.8 DeoR family transcriptional regulator compare
BWI76_RS24285 -4.1 -8.3 cystathionine beta-lyase compare
BWI76_RS17720 -4.1 -2.0 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS07675 -4.1 -7.7 DeoR family transcriptional regulator compare
BWI76_RS09660 -4.0 -2.8 DNA translocase FtsK compare
BWI76_RS08385 -4.0 -3.3 citrate (Si)-synthase compare
BWI76_RS22760 -4.0 -10.6 sulfite reductase subunit beta compare
BWI76_RS22755 -4.0 -5.8 phosphoadenosine phosphosulfate reductase compare
BWI76_RS01325 -4.0 -3.5 twin-arginine translocase subunit TatB compare
BWI76_RS23365 -3.9 -8.8 LysR family transcriptional regulator compare
BWI76_RS20435 -3.8 -1.9 chorismate synthase compare
BWI76_RS11965 -3.8 -4.0 orotidine-5'-phosphate decarboxylase compare
BWI76_RS23240 -3.8 -3.7 exonuclease V subunit gamma compare
BWI76_RS03010 -3.8 -6.7 ornithine carbamoyltransferase compare
BWI76_RS22765 -3.8 -13.6 sulfite reductase subunit alpha compare
BWI76_RS08395 -3.7 -2.6 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS11845 -3.7 -3.2 tryptophan synthase subunit beta compare
BWI76_RS25355 -3.7 -6.7 cell division protein ZapE compare
BWI76_RS07065 -3.5 -9.0 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS21465 -3.5 -3.1 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS20995 -3.5 -4.7 RNA degradosome polyphosphate kinase compare
BWI76_RS18955 -3.5 -6.2 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS00400 -3.5 -2.0 glutamine synthetase compare
BWI76_RS20270 -3.4 -6.1 hypothetical protein compare
BWI76_RS23230 -3.4 -2.3 exodeoxyribonuclease V subunit beta compare
BWI76_RS27390 -3.3 -2.9 ribonuclease PH compare
BWI76_RS27475 -3.2 -9.1 regulatory protein GntR family protein compare
BWI76_RS01185 -3.2 -2.2 adenylate cyclase compare
BWI76_RS20130 -3.2 -7.1 NADH-quinone oxidoreductase subunit N compare
BWI76_RS20160 -3.1 -2.8 NADH-quinone oxidoreductase subunit H compare
BWI76_RS27170 -3.1 -6.5 MltR family transcriptional regulator compare
BWI76_RS08390 -3.1 -4.6 hypothetical protein compare
BWI76_RS20135 -3.0 -3.8 NADH-quinone oxidoreductase subunit M compare
BWI76_RS26760 -3.0 -5.1 C4-dicarboxylate transport protein DctA (from data) conserved
BWI76_RS00985 -3.0 -4.4 transcriptional regulator IlvY compare
BWI76_RS19650 -3.0 -6.4 DNA-binding transcriptional regulator GalS conserved
BWI76_RS26095 -2.9 -2.0 shikimate kinase compare
BWI76_RS08205 -2.9 -5.0 DNA-binding transcriptional dual regulator NagC compare
BWI76_RS20170 -2.8 -4.6 NADH-quinone oxidoreductase subunit F compare
BWI76_RS02530 -2.8 -3.1 tRNA dimethylallyltransferase compare
BWI76_RS20145 -2.7 -2.1 NADH-quinone oxidoreductase subunit K compare
BWI76_RS20650 -2.7 -2.6 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS20165 -2.7 -5.0 NADH-quinone oxidoreductase subunit G compare
BWI76_RS16275 -2.6 -3.0 fumarate hydratase FumA compare
BWI76_RS06490 -2.4 -4.5 cytochrome ubiquinol oxidase subunit I compare
BWI76_RS06730 -2.4 -3.6 lac repressor compare
BWI76_RS06475 -2.4 -1.6 protoheme IX farnesyltransferase compare
BWI76_RS06485 -2.4 -3.4 cytochrome o ubiquinol oxidase subunit III compare
BWI76_RS20140 -2.4 -5.4 NADH-quinone oxidoreductase subunit L compare
BWI76_RS08520 -2.4 -3.0 colicin transporter TolQ compare
BWI76_RS06185 -2.3 -8.6 shikimate kinase II compare
BWI76_RS22700 -2.3 -4.2 sulfate adenylyltransferase subunit 2 compare
BWI76_RS08210 -2.3 -2.2 N-acetylglucosamine-6-phosphate deacetylase compare
BWI76_RS20190 -2.3 -4.2 NADH-quinone oxidoreductase subunit A compare
BWI76_RS02735 -2.2 -4.9 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS11520 -2.2 -1.3 hypothetical protein compare
BWI76_RS27075 -2.2 -5.6 IclR family transcriptional regulator compare
BWI76_RS20150 -2.2 -1.1 NADH:ubiquinone oxidoreductase subunit J compare
BWI76_RS24850 -2.2 -7.5 DeoR family transcriptional regulator compare
BWI76_RS03415 -2.2 -3.9 LacI family transcriptional regulator compare
BWI76_RS22695 -2.2 -4.9 sulfate adenylyltransferase compare
BWI76_RS02610 -2.1 -4.2 transcriptional regulator compare
BWI76_RS05790 -2.1 -1.9 phage DNA-binding protein compare
BWI76_RS01385 -2.1 -2.6 potassium transporter compare
BWI76_RS22690 -2.1 -2.2 adenylyl-sulfate kinase compare
BWI76_RS16360 -2.1 -1.8 electron transport complex subunit RsxB compare
BWI76_RS05120 -2.1 -6.1 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS24195 -2.0 -15.8 anion transporter compare
BWI76_RS20180 -2.0 -5.5 NADH-quinone oxidoreductase subunit C/D compare
BWI76_RS26075 -2.0 -2.3 DNA adenine methylase compare
BWI76_RS01070 -2.0 -6.6 thiol reductase thioredoxin compare
BWI76_RS26055 -2.0 -5.0 siroheme synthase compare
BWI76_RS06495 -2.0 -6.6 cytochrome ubiquinol oxidase subunit II compare
BWI76_RS27225 -1.9 -2.3 rhodanese-like domain-containing protein compare
BWI76_RS08525 -1.9 -2.6 colicin transporter compare
BWI76_RS02970 -1.8 -3.9 trehalose operon repressor compare
BWI76_RS23355 -1.8 -4.4 LacI family transcriptional regulator compare
BWI76_RS01680 -1.8 -4.1 transcriptional regulator IclR compare
BWI76_RS19705 -1.7 -3.6 kinase compare
BWI76_RS21685 -1.7 -1.6 hypothetical protein compare
BWI76_RS19730 -1.7 -2.2 1-phosphofructokinase compare
BWI76_RS23915 -1.7 -2.4 5-formyltetrahydrofolate cyclo-ligase compare
BWI76_RS27165 -1.6 -4.0 mannitol-1-phosphate 5-dehydrogenase compare
BWI76_RS04200 -1.6 -1.9 phosphoglycerate mutase GpmB compare
BWI76_RS08215 -1.6 -3.3 glucosamine-6-phosphate deaminase compare
BWI76_RS22815 -1.6 -8.0 hybrid sensor histidine kinase/response regulator compare
BWI76_RS20640 -1.6 -4.9 cysteine synthase A compare
BWI76_RS08730 -1.6 -2.7 histidine utilization repressor compare
BWI76_RS13575 -1.6 -4.0 sugar binding transcriptional regulator, LacI family protein compare
BWI76_RS20750 -1.5 -1.1 carboxysome structural protein EutK compare
BWI76_RS07120 -1.5 -8.0 LacI family transcriptional regulator compare
BWI76_RS26620 -1.5 -1.2 Fe-S biogenesis protein NfuA compare
BWI76_RS02050 -1.5 -1.8 CidA/LrgA family protein compare
BWI76_RS01200 -1.5 -2.2 diaminopimelate epimerase compare
BWI76_RS15825 -1.4 -1.3 hypothetical protein compare
BWI76_RS26310 -1.4 -6.1 IclR family transcriptional regulator compare
BWI76_RS21140 -1.4 -1.5 molecular chaperone HscA compare
BWI76_RS25960 -1.4 -3.1 NUDIX hydrolase compare
BWI76_RS00600 -1.4 -5.7 LacI family transcriptional regulator compare
BWI76_RS11835 -1.4 -2.0 putative regulatory protein MarR compare
BWI76_RS05680 -1.4 -3.2 LacI family transcriptional regulator compare
BWI76_RS21985 -1.4 -6.9 acetaldehyde dehydrogenase (EC 1.2.1.3) (from data) compare
BWI76_RS24740 -1.4 -2.1 GntR family transcriptional regulator compare
BWI76_RS15830 -1.4 -2.2 hypothetical protein compare
BWI76_RS25425 -1.4 -1.6 arginine repressor compare
BWI76_RS25905 -1.4 -2.2 hypothetical protein compare
BWI76_RS25060 -1.3 -2.7 lipoprotein NlpI compare
BWI76_RS25480 -1.3 -1.7 ribonuclease E/G compare
BWI76_RS17300 -1.3 -2.1 tRNA-Tyr compare
BWI76_RS20440 -1.3 -2.4 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS03225 -1.3 -5.7 transcriptional regulator compare
BWI76_RS01205 -1.3 -1.7 DUF484 family protein compare
BWI76_RS01350 -1.3 -0.9 NAD(P)H-flavin reductase compare
BWI76_RS02095 -1.3 -6.3 acetyl-coenzyme A synthetase compare
BWI76_RS19685 -1.3 -4.5 lysine transporter compare
BWI76_RS19330 -1.3 -1.2 HAD family hydrolase compare
BWI76_RS00240 -1.3 -1.8 FMN-binding protein MioC compare
BWI76_RS11300 -1.3 -1.3 cupin compare
BWI76_RS18335 -1.3 -6.1 DNA-binding response regulator compare
BWI76_RS16315 -1.3 -1.7 SirA-like protein compare
BWI76_RS27430 -1.3 -1.1 (p)ppGpp synthetase compare
BWI76_RS00765 -1.3 -4.4 DNA-binding transcriptional regulator CytR compare
BWI76_RS10795 -1.2 -4.8 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) (from data) compare
BWI76_RS14835 -1.2 -1.6 hypothetical protein compare
BWI76_RS03595 -1.2 -1.3 ethanolamine utilization protein EutM compare
BWI76_RS01170 -1.2 -3.3 uroporphyrinogen-III C-methyltransferase compare
BWI76_RS07725 -1.2 -1.2 iron-enterobactin transporter permease compare
BWI76_RS21690 -1.2 -2.0 hypothetical protein compare
BWI76_RS23265 -1.2 -2.1 hypothetical protein compare
BWI76_RS13280 -1.2 -4.6 LysR family transcriptional regulator compare
BWI76_RS18755 -1.2 -1.1 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS27940 -1.2 -2.5 2-dehydro-3-deoxy-6-phosphogalactonate aldolase compare
BWI76_RS08535 -1.2 -1.9 translocation protein TolB compare


Specific Phenotypes

For 11 genes in this experiment

For carbon source Sodium succinate dibasic hexahydrate in Klebsiella michiganensis M5al

For carbon source Sodium succinate dibasic hexahydrate across organisms