Experiment set5IT048 for Methanococcus maripaludis S2

Compare to:

H2 McCas- cells grown in liquid medium with neomycin

200 most important genes:

  gene name fitness t score description  
MMP_RS03340 -2.2 -0.9 ABC transporter ATP-binding protein compare
MMP_RS00295 -1.9 -2.1 gamma carbonic anhydrase family protein compare
MMP_RS07355 -1.9 -0.8 transcription factor S compare
MMP_RS03485 -1.9 -2.0 TIGR00267 family protein compare
MMP_RS02010 -1.9 -5.8 PHP domain-containing protein compare
MMP_RS02280 -1.8 -0.7 DUF211 domain-containing protein compare
MMP_RS06355 -1.5 -1.2 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS07540 -1.5 -2.3 CBS domain-containing protein compare
MMP_RS06840 -1.5 -0.9 DNA-directed RNA polymerase subunit N compare
MMP_RS06285 -1.5 -1.0 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS08350 -1.4 -0.8 hypothetical protein compare
MMP_RS03390 -1.4 -3.3 malate dehydrogenase compare
MMP_RS05550 -1.3 -0.5 cation:proton antiporter compare
MMP_RS05355 -1.3 -0.7 hypothetical protein compare
MMP_RS02745 -1.3 -1.5 hypothetical protein compare
MMP_RS03490 -1.3 -1.3 DUF2115 domain-containing protein compare
MMP_RS01445 -1.2 -2.9 hypothetical protein compare
MMP_RS02605 -1.2 -0.7 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS01830 -1.2 -0.9 tRNA-Val compare
MMP_RS08500 -1.2 -2.9 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMP_RS06350 -1.1 -2.4 HesA/MoeB/ThiF family protein compare
MMP_RS05425 -1.1 -1.7 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS01440 -1.1 -3.8 NAAT family transporter compare
MMP_RS03015 -1.1 -2.7 GTP 3' 8-cyclase MoaA compare
MMP_RS03520 -1.1 -1.5 YwbE family protein compare
MMP_RS07525 -1.1 -3.2 4Fe-4S binding protein compare
MMP_RS07845 -1.1 -1.0 LL-diaminopimelate aminotransferase compare
MMP_RS01220 -1.0 -2.4 hypothetical protein compare
MMP_RS05815 -1.0 -1.2 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS08725 -1.0 -1.5 Ni/Fe hydrogenase subunit alpha compare
MMP_RS05515 -1.0 -1.6 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS06340 -0.9 -2.5 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS07545 -0.9 -0.5 HTH domain-containing protein compare
MMP_RS01180 -0.9 -0.9 XTP/dITP diphosphatase compare
MMP_RS07635 -0.9 -1.0 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS06540 -0.9 -1.2 3-methyl-2-oxobutanoate dehydrogenase subunit VorB compare
MMP_RS02875 -0.9 -3.0 chorismate pyruvate-lyase family protein compare
MMP_RS08370 -0.9 -0.3 cation:proton antiporter subunit C compare
MMP_RS06525 -0.9 -0.8 YciI family protein compare
MMP_RS01240 -0.9 -1.1 7-cyano-7-deazaguanine synthase QueC compare
MMP_RS07850 -0.9 -1.4 prephenate dehydratase compare
MMP_RS05920 -0.8 -0.3 50S ribosomal protein L37e compare
MMP_RS05280 -0.8 -4.0 COG1361 S-layer family protein compare
MMP_RS01005 -0.8 -0.5 riboflavin synthase compare
MMP_RS04195 -0.8 -1.5 flavodoxin compare
MMP_RS01075 -0.8 -1.1 hypothetical protein compare
MMP_RS04875 -0.8 -1.9 energy-converting hydrogenase B subunit P compare
MMP_RS08995 -0.8 -0.8 hypothetical protein compare
MMP_RS08360 -0.8 -2.1 hypothetical protein compare
MMP_RS07575 -0.8 -1.4 RNA ligase partner protein compare
MMP_RS01365 -0.7 -1.4 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS01325 -0.7 -0.8 dihydroneopterin aldolase family protein compare
MMP_RS05285 -0.7 -2.0 MMPL family transporter compare
MMP_RS08785 -0.7 -0.5 RNA-protein complex protein Nop10 compare
MMP_RS01175 -0.7 -1.0 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS06325 -0.7 -0.8 hypothetical protein compare
MMP_RS00535 -0.7 -0.8 TIGR00375 family protein compare
MMP_RS06175 -0.7 -2.1 winged helix-turn-helix transcriptional regulator compare
MMP_RS07955 -0.7 -1.1 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS06190 -0.7 -2.8 tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO compare
MMP_RS08990 -0.7 -2.6 hypothetical protein compare
MMP_RS03800 -0.7 -1.3 hypothetical protein compare
MMP_RS00770 -0.7 -1.7 hypothetical protein compare
MMP_RS08335 -0.7 -2.1 NADH-quinone oxidoreductase subunit B family protein compare
MMP_RS03450 -0.7 -0.8 glycine synthesis protein GlyXS (from data) compare
MMP_RS02100 -0.7 -1.6 metallophosphoesterase compare
MMP_RS08340 -0.7 -1.3 4Fe-4S binding protein compare
MMP_RS02835 -0.6 -1.6 CGGC domain-containing protein compare
MMP_RS07605 -0.6 -0.7 diadenylate cyclase compare
MMP_RS01675 -0.6 -0.6 hypothetical protein compare
MMP_RS02235 -0.6 -2.7 CBS domain-containing protein compare
MMP_RS06530 -0.6 -1.6 bifunctional hexulose-6-phosphate synthase/ribonuclease regulator compare
MMP_RS00530 -0.6 -1.5 tRNA pseudouridine(54/55) synthase Pus10 compare
MMP_RS08165 -0.6 -1.2 phosphoglycerate dehydrogenase compare
MMP_RS00040 -0.6 -1.4 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS01460 -0.6 -1.2 hypothetical protein compare
MMP_RS06575 -0.6 -1.3 fluoride efflux transporter CrcB compare
MMP_RS07815 -0.6 -0.5 DUF2120 domain-containing protein compare
MMP_RS00695 -0.6 -0.3 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS01500 -0.5 -0.4 CBS domain-containing protein compare
MMP_RS06765 -0.5 -1.9 flap endonuclease-1 compare
MMP_RS03095 -0.5 -1.4 diphthine synthase compare
MMP_RS01150 -0.5 -2.3 aldo/keto reductase compare
MMP_RS02940 -0.5 -2.8 TatD family hydrolase compare
MMP_RS05800 -0.5 -2.1 B12-binding domain-containing radical SAM protein compare
MMP_RS01840 -0.5 -2.0 TIGR00289 family protein compare
MMP_RS03225 -0.5 -1.4 acetolactate decarboxylase compare
MMP_RS03305 -0.5 -1.7 winged helix-turn-helix domain-containing protein compare
MMP_RS01055 -0.5 -1.3 hypothetical protein compare
MMP_RS06870 -0.5 -1.9 DedA family protein compare
MMP_RS03840 -0.5 -1.1 hypothetical protein compare
MMP_RS01225 -0.5 -1.0 DUF5379 domain-containing protein compare
MMP_RS00125 -0.5 -0.6 DUF2798 domain-containing protein compare
MMP_RS01755 -0.5 -0.4 DUF2097 domain-containing protein compare
MMP_RS05965 -0.5 -1.5 carboxymuconolactone decarboxylase family protein compare
MMP_RS02265 -0.5 -1.3 nitroreductase family protein compare
MMP_RS06385 -0.5 -1.5 hypothetical protein compare
MMP_RS05175 -0.5 -1.4 hypothetical protein compare
MMP_RS02595 -0.5 -0.6 putative zinc-binding protein compare
MMP_RS04100 -0.5 -1.2 hypothetical protein compare
MMP_RS06335 -0.5 -1.4 HAD family hydrolase compare
MMP_RS00750 -0.5 -0.4 fumarate hydratase compare
MMP_RS01020 -0.5 -0.4 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS07750 -0.4 -0.8 DUF357 domain-containing protein compare
MMP_RS03035 -0.4 -0.4 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS07895 -0.4 -0.9 cytochrome c compare
MMP_RS04360 -0.4 -1.2 hypothetical protein compare
MMP_RS07710 -0.4 -1.7 cell division protein FtsZ compare
MMP_RS05290 -0.4 -2.1 TetR/AcrR family transcriptional regulator compare
MMP_RS06445 -0.4 -1.0 DUF89 domain-containing protein compare
MMP_RS02490 -0.4 -0.9 hypothetical protein compare
MMP_RS08435 -0.4 -0.4 Era-like GTP-binding protein compare
MMP_RS06630 -0.4 -0.2 UPF0058 family protein compare
MMP_RS04050 -0.4 -0.8 hypothetical protein compare
MMP_RS01370 -0.4 -1.8 acetate--CoA ligase family protein compare
MMP_RS01865 -0.4 -0.5 GPR1/FUN34/YaaH family transporter compare
MMP_RS02370 -0.4 -0.7 NifB/NifX family molybdenum-iron cluster-binding protein compare
MMP_RS02045 -0.4 -0.5 tRNA-Met compare
MMP_RS01660 -0.4 -0.7 hypothetical protein compare
MMP_RS00665 -0.4 -1.3 hypothetical protein compare
MMP_RS01080 -0.4 -1.4 DUF2202 domain-containing protein compare
MMP_RS07535 -0.4 -1.8 4Fe-4S binding protein compare
MMP_RS08330 -0.4 -1.0 NADH-quinone oxidoreductase subunit H compare
MMP_RS02320 -0.4 -1.8 glutamate-cysteine ligase family protein compare
MMP_RS01870 -0.4 -2.4 acyl-CoA dehydratase activase compare
MMP_RS03065 -0.4 -0.8 AzlC family ABC transporter permease compare
MMP_RS06980 -0.4 -1.1 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS05865 -0.4 -1.1 hypothetical protein compare
MMP_RS08310 -0.4 -0.5 TMEM165/GDT1 family protein compare
MMP_RS01620 -0.4 -1.0 hypothetical protein compare
MMP_RS04125 -0.4 -1.0 TetR/AcrR family transcriptional regulator compare
MMP_RS02965 -0.4 -0.7 carboxymuconolactone decarboxylase family protein compare
MMP_RS02690 -0.4 -1.2 FmdE family protein compare
MMP_RS02130 -0.4 -1.5 zinc metalloprotease HtpX compare
MMP_RS04190 -0.4 -1.5 hypothetical protein compare
MMP_RS01265 -0.4 -0.5 hypothetical protein compare
MMP_RS06700 -0.4 -1.7 hypothetical protein compare
MMP_RS04320 -0.3 -2.4 uroporphyrinogen decarboxylase family protein compare
MMP_RS05110 -0.3 -1.6 16S ribosomal RNA methyltransferase A compare
MMP_RS06005 -0.3 -1.3 heavy-metal-associated domain-containing protein compare
MMP_RS06395 -0.3 -0.8 ThiF family adenylyltransferase compare
MMP_RS02935 -0.3 -0.8 A24 family peptidase compare
MMP_RS07090 -0.3 -1.1 tRNA (adenine-N1)-methyltransferase compare
MMP_RS04105 -0.3 -1.7 MarR family transcriptional regulator compare
MMP_RS05790 -0.3 -1.2 HDIG domain-containing protein compare
MMP_RS00385 -0.3 -1.3 P-II family nitrogen regulator compare
MMP_RS07970 -0.3 -0.8 hypothetical protein compare
MMP_RS02550 -0.3 -1.0 helix-turn-helix transcriptional regulator compare
MMP_RS07795 -0.3 -1.8 site-2 protease family protein compare
MMP_RS04735 -0.3 -1.4 tautomerase family protein compare
MMP_RS01415 -0.3 -0.8 DUF2067 domain-containing protein compare
MMP_RS04850 -0.3 -2.1 UPF0254 family protein compare
MMP_RS06920 -0.3 -1.9 AAA family ATPase compare
MMP_RS07685 -0.3 -1.3 TIGR01212 family radical SAM protein compare
MMP_RS00700 -0.3 -1.1 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS03145 -0.3 -0.9 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS04225 -0.3 -1.6 hypothetical protein compare
MMP_RS07915 -0.3 -1.3 DUF4870 domain-containing protein compare
MMP_RS05140 -0.3 -0.9 helix-turn-helix transcriptional regulator compare
MMP_RS07095 -0.3 -0.7 PspC domain-containing protein compare
MMP_RS05485 -0.3 -1.4 cysteine--tRNA ligase compare
MMP_RS06680 -0.3 -1.8 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS03985 -0.3 -1.9 hypothetical protein compare
MMP_RS08240 -0.3 -1.3 methanogenesis marker 16 metalloprotein compare
MMP_RS02230 -0.3 -1.4 sodium-dependent transporter compare
MMP_RS05545 -0.3 -1.1 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS04675 -0.3 -1.3 selenouridine synthase SelU-like subunit compare
MMP_RS07550 -0.3 -1.6 L-serine ammonia-lyase iron-sulfur-dependent subunit alpha compare
MMP_RS05460 -0.3 -1.4 YcaO-related McrA-glycine thioamidation protein compare
MMP_RS05020 -0.3 -0.7 hypothetical protein compare
MMP_RS02300 -0.3 -1.0 NAD(P)H-dependent oxidoreductase compare
MMP_RS01115 -0.3 -1.3 molybdopterin molybdotransferase MoeA compare
MMP_RS06770 -0.3 -1.2 DHH family phosphoesterase compare
MMP_RS00560 -0.3 -1.5 cation:proton antiporter compare
MMP_RS02395 -0.3 -1.4 hypothetical protein compare
MMP_RS06610 -0.3 -0.7 DUF2334 domain-containing protein compare
MMP_RS08840 -0.3 -1.4 class I SAM-dependent methyltransferase compare
MMP_RS02175 -0.3 -0.2 DUF1611 domain-containing protein compare
MMP_RS02830 -0.3 -1.3 DUF432 domain-containing protein compare
MMP_RS03590 -0.3 -0.7 METTL5 family protein compare
MMP_RS05125 -0.3 -1.5 D-aminoacyl-tRNA deacylase compare
MMP_RS01335 -0.3 -0.5 prefoldin subunit beta compare
MMP_RS06585 -0.3 -0.4 DMT family protein compare
MMP_RS08390 -0.3 -1.1 DUF5400 domain-containing protein compare
MMP_RS01085 -0.3 -0.5 hypothetical protein compare
MMP_RS04340 -0.3 -1.9 uroporphyrinogen decarboxylase compare
MMP_RS05555 -0.3 -0.3 DUF4040 domain-containing protein compare
MMP_RS05505 -0.3 -1.2 class IV adenylate cyclase compare
MMP_RS00620 -0.3 -0.8 4Fe-4S binding protein compare
MMP_RS04965 -0.3 -1.3 thioredoxin family protein compare
MMP_RS03235 -0.3 -0.9 tRNA pseudouridine(13) synthase TruD compare
MMP_RS01860 -0.3 -0.9 hypothetical protein compare
MMP_RS01330 -0.3 -1.7 DHH family phosphoesterase compare
MMP_RS05060 -0.3 -1.6 AAA family ATPase compare
MMP_RS07645 -0.3 -0.8 aldehyde dehydrogenase family protein compare
MMP_RS08690 -0.3 -1.1 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 compare
MMP_RS08315 -0.3 -0.5 S-methyl-5-thioribose-1-phosphate isomerase compare
MMP_RS07365 -0.2 -1.0 2-phosphoglycerate kinase compare
MMP_RS02975 -0.2 -0.8 DUF2124 domain-containing protein compare
MMP_RS02570 -0.2 -1.7 cation:proton antiporter compare


Specific Phenotypes

For 1 genes in this experiment

For natural competence Neomycin trisulfate salt hydrate in Methanococcus maripaludis S2

For natural competence Neomycin trisulfate salt hydrate across organisms