Experiment set5IT048 for Klebsiella michiganensis M5al

Compare to:

Sodium pyruvate carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS18950 -7.7 -5.3 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS21475 -7.3 -7.1 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS04675 -7.0 -6.8 3-isopropylmalate dehydrogenase compare
BWI76_RS05840 -6.9 -4.8 glutamate 5-kinase compare
BWI76_RS18920 -6.8 -4.7 ATP phosphoribosyltransferase compare
BWI76_RS18935 -6.6 -9.0 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS04250 -6.6 -7.8 homoserine kinase compare
BWI76_RS00805 -6.4 -6.2 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS05015 -6.2 -4.3 transcriptional regulator compare
BWI76_RS04470 -6.1 -10.9 carbamoyl phosphate synthase large subunit compare
BWI76_RS08385 -5.9 -3.4 citrate (Si)-synthase compare
BWI76_RS18940 -5.9 -6.3 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS24285 -5.7 -7.8 cystathionine beta-lyase compare
BWI76_RS09755 -5.7 -9.5 phosphoserine transaminase compare
BWI76_RS00990 -5.6 -8.6 ketol-acid reductoisomerase compare
BWI76_RS01655 -5.6 -9.5 homoserine O-succinyltransferase compare
BWI76_RS09760 -5.5 -7.5 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS26085 -5.5 -3.8 3-dehydroquinate synthase compare
BWI76_RS18955 -5.4 -5.1 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS18930 -5.3 -5.4 histidinol-phosphate transaminase compare
BWI76_RS00850 -5.2 -9.1 acetylglutamate kinase compare
BWI76_RS04645 -5.2 -4.9 3-dehydroquinase compare
BWI76_RS04160 -5.1 -4.6 phosphoserine phosphatase compare
BWI76_RS23920 -5.0 -4.5 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS00855 -5.0 -7.7 argininosuccinate lyase compare
BWI76_RS25115 -4.9 -9.4 argininosuccinate synthase compare
BWI76_RS17065 -4.9 -9.8 phosphoenolpyruvate synthase compare
BWI76_RS18925 -4.9 -7.0 histidinol dehydrogenase compare
BWI76_RS04670 -4.9 -9.1 3-isopropylmalate dehydratase large subunit compare
BWI76_RS05835 -4.9 -4.7 gamma-glutamyl-phosphate reductase compare
BWI76_RS04255 -4.8 -10.4 threonine synthase compare
BWI76_RS00785 -4.8 -5.7 cystathionine gamma-synthase compare
BWI76_RS02815 -4.8 -3.5 fructose-bisphosphatase class I compare
BWI76_RS20895 -4.8 -7.2 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS04245 -4.7 -15.6 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS11965 -4.6 -3.9 orotidine-5'-phosphate decarboxylase compare
BWI76_RS01615 -4.6 -12.2 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS11845 -4.6 -2.0 tryptophan synthase subunit beta compare
BWI76_RS04705 -4.5 -8.0 DNA-binding transcriptional regulator FruR compare
BWI76_RS11855 -4.5 -8.9 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS11860 -4.5 -8.3 anthranilate synthase component I compare
BWI76_RS11850 -4.4 -8.6 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS10990 -4.3 -5.1 dihydroorotase compare
BWI76_RS11840 -4.3 -6.5 tryptophan synthase subunit alpha compare
BWI76_RS04240 -4.2 -1.9 thr operon leader peptide compare
BWI76_RS04465 -4.2 -4.9 carbamoyl-phosphate synthase small subunit compare
BWI76_RS03010 -4.2 -6.4 ornithine carbamoyltransferase compare
BWI76_RS21465 -4.2 -5.3 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS04665 -4.2 -16.5 3-isopropylmalate dehydratase small subunit compare
BWI76_RS00845 -4.1 -9.3 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS00980 -4.1 -9.6 PLP-dependent threonine dehydratase compare
BWI76_RS23360 -4.1 -2.6 diaminopimelate decarboxylase compare
BWI76_RS00835 -4.1 -14.4 phosphoenolpyruvate carboxylase compare
BWI76_RS00975 -4.1 -10.8 dihydroxy-acid dehydratase compare
BWI76_RS09910 -4.0 -15.6 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS02995 -3.9 -6.7 aspartate carbamoyltransferase compare
BWI76_RS07070 -3.9 -6.9 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS04685 -3.9 -8.4 putative leucine operon leader peptide compare
BWI76_RS07065 -3.8 -8.7 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS20435 -3.8 -2.2 chorismate synthase compare
BWI76_RS22755 -3.7 -8.6 phosphoadenosine phosphosulfate reductase compare
BWI76_RS23365 -3.7 -8.8 LysR family transcriptional regulator compare
BWI76_RS22690 -3.6 -5.4 adenylyl-sulfate kinase compare
BWI76_RS23220 -3.6 -7.4 amino-acid N-acetyltransferase compare
BWI76_RS23240 -3.6 -3.5 exonuclease V subunit gamma compare
BWI76_RS25645 -3.5 -9.1 shikimate dehydrogenase compare
BWI76_RS00400 -3.4 -2.3 glutamine synthetase compare
BWI76_RS27385 -3.4 -6.8 orotate phosphoribosyltransferase compare
BWI76_RS20965 -3.4 -4.3 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS20355 -3.3 -4.5 colicin V production protein compare
BWI76_RS00960 -3.3 -6.5 acetolactate synthase 2 catalytic subunit compare
BWI76_RS02735 -3.3 -5.5 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS20350 -3.3 -6.5 amidophosphoribosyltransferase compare
BWI76_RS04680 -3.3 -6.7 2-isopropylmalate synthase compare
BWI76_RS21265 -3.3 -10.8 phosphoribosylformylglycinamidine synthase compare
BWI76_RS00965 -3.3 -1.9 acetolactate synthase 2 small subunit compare
BWI76_RS17720 -3.3 -2.3 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS21140 -3.2 -3.3 molecular chaperone HscA compare
BWI76_RS09660 -3.2 -3.0 DNA translocase FtsK compare
BWI76_RS22760 -3.2 -10.5 sulfite reductase subunit beta compare
BWI76_RS22765 -3.2 -9.4 sulfite reductase subunit alpha compare
BWI76_RS00985 -3.1 -7.1 transcriptional regulator IlvY compare
BWI76_RS26570 -3.1 -4.6 anion permease compare
BWI76_RS15825 -2.9 -3.3 hypothetical protein compare
BWI76_RS09645 -2.9 -2.0 thioredoxin-disulfide reductase compare
BWI76_RS01610 -2.8 -8.0 phosphoribosylamine--glycine ligase compare
BWI76_RS26000 -2.8 -9.6 aspartate aminotransferase family protein compare
BWI76_RS01210 -2.7 -4.0 tyrosine recombinase XerC compare
BWI76_RS16315 -2.5 -2.4 SirA-like protein compare
BWI76_RS23230 -2.5 -4.0 exodeoxyribonuclease V subunit beta compare
BWI76_RS20640 -2.5 -6.4 cysteine synthase A compare
BWI76_RS27390 -2.4 -2.5 ribonuclease PH compare
BWI76_RS22805 -2.4 -8.4 GTP diphosphokinase compare
BWI76_RS25320 -2.3 -6.5 glutamate synthase compare
BWI76_RS08405 -2.3 -4.4 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS20795 -2.2 -1.5 ethanolamine catabolic microcompartment shell protein EutN compare
BWI76_RS04715 -2.2 -2.5 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS05200 -2.1 -3.3 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS11430 -2.1 -1.5 lipoprotein compare
BWI76_RS03595 -2.0 -2.0 ethanolamine utilization protein EutM compare
BWI76_RS26055 -2.0 -7.8 siroheme synthase compare
BWI76_RS26460 -2.0 -4.5 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS06340 -2.0 -1.8 hypothetical protein compare
BWI76_RS04515 -1.9 -2.1 Co2+/Mg2+ efflux protein ApaG compare
BWI76_RS02180 -1.9 -1.2 hypothetical protein compare
BWI76_RS11900 -1.9 -1.7 cob(I)yrinic acid a,c-diamide adenosyltransferase compare
BWI76_RS15760 -1.8 -2.4 hypothetical protein compare
BWI76_RS15830 -1.6 -3.8 hypothetical protein compare
BWI76_RS08425 -1.6 -4.7 succinyl-CoA ligase subunit beta compare
BWI76_RS01275 -1.6 -4.6 LysR family transcriptional regulator compare
BWI76_RS20970 -1.6 -1.9 phosphoribosylglycinamide formyltransferase compare
BWI76_RS25315 -1.5 -7.9 glutamate synthase large subunit compare
BWI76_RS00390 -1.5 -4.5 two-component system sensor histidine kinase NtrB compare
BWI76_RS26620 -1.4 -1.4 Fe-S biogenesis protein NfuA compare
BWI76_RS04530 -1.4 -2.3 peptidylprolyl isomerase SurA compare
BWI76_RS23480 -1.4 -7.2 EAL domain-containing protein compare
BWI76_RS15835 -1.4 -0.9 hypothetical protein compare
BWI76_RS20440 -1.4 -2.1 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS09190 -1.4 -3.4 hypothetical protein compare
BWI76_RS02410 -1.4 -1.9 EF-P beta-lysylation protein EpmB compare
BWI76_RS15635 -1.3 -2.6 hypothetical protein compare
BWI76_RS23885 -1.3 -1.7 2-octaprenylphenol hydroxylase compare
BWI76_RS16275 -1.3 -1.5 fumarate hydratase FumA compare
BWI76_RS04525 -1.3 -2.0 4-hydroxythreonine-4-phosphate dehydrogenase PdxA compare
BWI76_RS11700 -1.2 -1.2 hypothetical protein compare
BWI76_RS01185 -1.2 -2.2 adenylate cyclase compare
BWI76_RS08430 -1.2 -4.2 succinate--CoA ligase subunit alpha compare
BWI76_RS06295 -1.2 -3.9 S-adenosylmethionine:tRNA ribosyltransferase-isomerase compare
BWI76_RS09255 -1.2 -1.8 hypothetical protein compare
BWI76_RS00345 -1.2 -2.2 protein disulfide oxidoreductase DsbA compare
BWI76_RS08395 -1.2 -2.0 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS01565 -1.1 -1.8 NADH pyrophosphatase compare
BWI76_RS22695 -1.1 -3.7 sulfate adenylyltransferase compare
BWI76_RS02985 -1.1 -3.9 reactive intermediate/imine deaminase compare
BWI76_RS21480 -1.1 -3.3 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS17770 -1.1 -1.6 isomerase/hydrolase compare
BWI76_RS09530 -1.1 -1.2 hypothetical protein compare
BWI76_RS07465 -1.1 -2.2 TetR family transcriptional regulator compare
BWI76_RS19730 -1.0 -2.9 1-phosphofructokinase compare
BWI76_RS15810 -1.0 -3.7 hypothetical protein compare
BWI76_RS10035 -1.0 -1.7 hypothetical protein compare
BWI76_RS15705 -1.0 -4.5 putative holin protein compare
BWI76_RS21165 -1.0 -1.7 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS06735 -1.0 -1.8 50S ribosomal protein L31 compare
BWI76_RS27440 -1.0 -2.4 DNA helicase RecG compare
BWI76_RS13560 -1.0 -1.0 amino acid ABC transporter substrate-binding subunit compare
BWI76_RS13770 -1.0 -1.5 alkylhydroperoxidase domain protein compare
BWI76_RS23055 -1.0 -1.4 cobalamin biosynthesis protein CbiG compare
BWI76_RS08500 -1.0 -1.8 cytochrome d ubiquinol oxidase subunit 2 compare
BWI76_RS00970 -1.0 -2.0 branched chain amino acid aminotransferase compare
BWI76_RS10745 -1.0 -1.0 hypothetical protein compare
BWI76_RS00355 -0.9 -2.5 DNA polymerase I compare
BWI76_RS08040 -0.9 -1.8 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH compare
BWI76_RS13160 -0.9 -1.9 azoreductase compare
BWI76_RS15650 -0.9 -3.0 gp5 compare
BWI76_RS25280 -0.9 -1.6 RNase adaptor protein RapZ compare
BWI76_RS07995 -0.9 -2.8 twin-arginine translocase subunit TatA compare
BWI76_RS15955 -0.9 -5.5 transcriptional regulator compare
BWI76_RS06185 -0.9 -5.1 shikimate kinase II compare
BWI76_RS25355 -0.9 -4.5 cell division protein ZapE compare
BWI76_RS24100 -0.9 -1.8 YggS family pyridoxal phosphate enzyme compare
BWI76_RS08390 -0.9 -1.9 hypothetical protein compare
BWI76_RS19010 -0.9 -2.4 polysaccharide pyruvyl transferase yvff compare
BWI76_RS11610 -0.9 -2.3 glutamate dehydrogenase compare
BWI76_RS10835 -0.9 -1.4 hypothetical protein compare
BWI76_RS05450 -0.9 -1.0 ribonuclease HI compare
BWI76_RS26440 -0.9 -1.1 hypothetical protein compare
BWI76_RS25485 -0.9 -1.2 septum formation protein Maf compare
BWI76_RS00385 -0.9 -5.3 nitrogen assimilation regulatory protein compare
BWI76_RS19850 -0.9 -2.5 tRNA-Pro compare
BWI76_RS17955 -0.9 -1.9 hypothetical protein compare
BWI76_RS26455 -0.9 -2.4 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS25335 -0.9 -2.0 stringent starvation protein A compare
BWI76_RS19670 -0.9 -2.2 S-formylglutathione hydrolase compare
BWI76_RS24900 -0.9 -1.1 DeoR family transcriptional regulator compare
BWI76_RS15060 -0.9 -2.0 MarR family transcriptional regulator compare
BWI76_RS06595 -0.9 -1.8 hypothetical protein compare
BWI76_RS19840 -0.9 -1.1 hypothetical protein compare
BWI76_RS12195 -0.8 -2.7 hypothetical protein compare
BWI76_RS03660 -0.8 -2.5 hypothetical protein compare
BWI76_RS17370 -0.8 -1.8 nitrate transporter NasD compare
BWI76_RS17300 -0.8 -1.6 tRNA-Tyr compare
BWI76_RS12145 -0.8 -2.0 hypothetical protein compare
BWI76_RS26045 -0.8 -1.5 nitrite reductase small subunit compare
BWI76_RS00180 -0.8 -0.7 F0F1 ATP synthase subunit epsilon compare
BWI76_RS14820 -0.8 -1.7 LysR family transcriptional regulator compare
BWI76_RS26395 -0.8 -3.3 cell division protein FtsE compare
BWI76_RS03880 -0.8 -1.1 homoprotocatechuate degradation operon regulator, HpaR compare
BWI76_RS09635 -0.8 -2.1 amino acid ABC transporter ATP-binding protein compare
BWI76_RS07740 -0.8 -0.9 Fe2+-enterobactin ABC transporter substrate-binding protein compare
BWI76_RS17100 -0.8 -2.3 glutathione peroxidase compare
BWI76_RS02625 -0.8 -2.5 PTS ascorbate transporter subunit IIB compare
BWI76_RS08530 -0.8 -1.8 protein TolA compare
BWI76_RS13435 -0.8 -1.4 hypothetical protein compare
BWI76_RS08520 -0.8 -1.7 colicin transporter TolQ compare
BWI76_RS26410 -0.8 -1.1 membrane protein compare
BWI76_RS08110 -0.8 -2.0 glutamate/aspartate ABC transporter substrate-binding protein compare
BWI76_RS23760 -0.8 -1.2 tRNA-Gly compare
BWI76_RS10040 -0.8 -1.5 heat-shock protein HspQ compare
BWI76_RS22090 -0.8 -1.5 transcriptional regulator compare


Specific Phenotypes

None in this experiment

For Klebsiella michiganensis M5al in carbon source experiments

For carbon source Sodium pyruvate across organisms