Experiment set5IT048 for Klebsiella michiganensis M5al

Compare to:

Sodium pyruvate carbon source

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS24575 +2.2 3.6 hypothetical protein compare
BWI76_RS11440 +1.3 2.2 hypothetical protein compare
BWI76_RS24885 +1.2 1.5 PTS galactitol transporter subunit IIB compare
BWI76_RS24920 +1.1 2.2 YraN family protein compare
BWI76_RS21375 +1.1 2.5 autonomous glycyl radical cofactor GrcA compare
BWI76_RS24110 +1.1 2.5 YggU family protein compare
BWI76_RS08380 +1.0 1.9 endonuclease VIII compare
BWI76_RS19835 +1.0 3.0 nucleoid-associated protein YejK compare
BWI76_RS09690 +0.9 2.8 dimethyl sulfoxide reductase compare
BWI76_RS15150 +0.9 3.1 outer membrane efflux protein compare
BWI76_RS11675 +0.9 1.8 arginine N-succinyltransferase compare
BWI76_RS16075 +0.9 1.6 oxidoreductase compare
BWI76_RS12465 +0.9 1.4 phage shock protein D compare
BWI76_RS19770 +0.9 1.5 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase compare
BWI76_RS18240 +0.9 2.1 L-arabinose ABC transporter permease AraH compare
BWI76_RS05075 +0.9 1.3 type II secretion system protein GspG compare
BWI76_RS11125 +0.9 1.6 metal-dependent hydrolase compare
BWI76_RS01680 +0.9 3.1 transcriptional regulator IclR compare
BWI76_RS03105 +0.9 1.3 myo-inosose-2 dehydratase compare
BWI76_RS10435 +0.9 1.9 suppressor for copper-sensitivity C compare
BWI76_RS17805 +0.9 1.4 membrane protein compare
BWI76_RS24180 +0.9 1.2 hypothetical protein compare
BWI76_RS08330 +0.8 1.7 hypothetical protein compare
BWI76_RS13980 +0.8 0.8 hypothetical protein compare
BWI76_RS23125 +0.8 1.5 propanediol dehydratase small subunit compare
BWI76_RS21245 +0.8 2.0 nitrogen regulatory protein P-II compare
BWI76_RS19235 +0.8 2.6 polar amino acid ABC transporter inner membrane subunit compare
BWI76_RS19585 +0.8 1.4 gentisate 1,2-dioxygenase compare
BWI76_RS19865 +0.8 1.7 ecotin compare
BWI76_RS05050 +0.8 2.7 general secretion pathway protein GspL compare
BWI76_RS26285 +0.8 2.9 glycerophosphodiester phosphodiesterase compare
BWI76_RS04560 +0.8 1.7 holo-ACP synthase CitX compare
BWI76_RS01995 +0.8 1.1 AraC family transcriptional regulator compare
BWI76_RS09625 +0.8 1.7 hypothetical protein compare
BWI76_RS03870 +0.8 1.8 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase compare
BWI76_RS21675 +0.8 1.4 hypothetical protein compare
BWI76_RS25600 +0.8 1.1 tRNA-Thr compare
BWI76_RS17975 +0.7 2.7 tail-specific protease compare
BWI76_RS18550 +0.7 1.5 tRNA-Asn compare
BWI76_RS04060 +0.7 1.1 hypothetical protein compare
BWI76_RS11435 +0.7 1.3 hypothetical protein compare
BWI76_RS25000 +0.7 0.8 malonate decarboxylase acyl carrier protein compare
BWI76_RS17390 +0.7 2.2 DsrE family protein compare
BWI76_RS00725 +0.7 2.1 periplasmic repressor CpxP compare
BWI76_RS16015 +0.7 2.5 pheromone autoinducer 2 transporter compare
BWI76_RS22935 +0.7 1.6 L-fucose mutarotase compare
BWI76_RS02860 +0.7 1.3 glycine dehydrogenase compare
BWI76_RS12925 +0.7 3.2 efflux transporter periplasmic adaptor subunit compare
BWI76_RS25935 +0.7 2.8 glutathione-regulated potassium-efflux system ancillary protein KefG compare
BWI76_RS14540 +0.7 1.6 yersiniabactin biosynthetic protein YbtU compare
BWI76_RS04895 +0.7 1.2 hypothetical protein compare
BWI76_RS13955 +0.7 2.1 hypothetical protein compare
BWI76_RS12670 +0.7 2.0 DNA polymerase V subunit UmuD compare
BWI76_RS22095 +0.7 2.4 multidrug export protein EmrA compare
BWI76_RS04305 +0.7 0.6 molecular chaperone DnaJ compare
BWI76_RS11970 +0.7 2.1 stress response translation initiation inhibitor YciH compare
BWI76_RS26575 +0.7 2.8 universal stress protein B compare
BWI76_RS19195 +0.7 2.4 nickel ABC transporter permease compare
BWI76_RS23320 +0.7 1.2 hypothetical protein compare
BWI76_RS11490 +0.7 2.7 MltA-interacting protein MipA compare
BWI76_RS27600 +0.7 2.0 tRNA-Sec compare
BWI76_RS18770 +0.7 0.9 DNA gyrase inhibitor compare
BWI76_RS08275 +0.7 1.2 LexA regulated protein compare
BWI76_RS17570 +0.7 1.0 iron-sulfur-binding protein compare
BWI76_RS19470 +0.7 1.8 DNA-binding response regulator compare
BWI76_RS21370 +0.7 0.8 ATP-dependent RNA helicase SrmB compare
BWI76_RS19310 +0.6 1.9 ABC transporter permease compare
BWI76_RS02580 +0.6 1.0 23S rRNA (guanosine(2251)-2'-O)-methyltransferase compare
BWI76_RS20610 +0.6 2.3 LysR family transcriptional regulator compare
BWI76_RS04955 +0.6 0.7 hypoxanthine phosphoribosyltransferase compare
BWI76_RS27745 +0.6 2.4 PTS sugar transporter subunit IIB compare
BWI76_RS01585 +0.6 2.9 transcriptional regulator compare
BWI76_RS16675 +0.6 0.7 ABC transporter compare
BWI76_RS00740 +0.6 1.7 ribonuclease E activity regulator RraA compare
BWI76_RS08210 +0.6 1.5 N-acetylglucosamine-6-phosphate deacetylase compare
BWI76_RS14575 +0.6 2.1 TENA/THI-4 family protein compare
BWI76_RS15660 +0.6 0.7 hypothetical protein compare
BWI76_RS05810 +0.6 1.0 hypothetical protein compare
BWI76_RS16400 +0.6 2.0 pyridoxal kinase compare
BWI76_RS21685 +0.6 1.2 hypothetical protein compare
BWI76_RS18230 +0.6 1.9 trehalose-6-phosphate synthase compare
BWI76_RS25245 +0.6 1.7 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase compare
BWI76_RS11895 +0.6 1.8 AraC family transcriptional regulator compare
BWI76_RS01530 +0.6 1.8 2-iminoacetate synthase ThiH compare
BWI76_RS06540 +0.6 1.7 DNA-binding protein HU-beta compare
BWI76_RS00240 +0.6 1.4 FMN-binding protein MioC compare
BWI76_RS18060 +0.6 0.9 hypothetical protein compare
BWI76_RS07785 +0.6 0.6 transcriptional regulator compare
BWI76_RS04565 +0.6 2.3 bifunctional tRNA pseudouridine(32) synthase/ribosomal large subunit pseudouridine synthase RluA compare
BWI76_RS23755 +0.6 2.7 transcriptional regulator compare
BWI76_RS21910 +0.6 1.7 glyoxylate/hydroxypyruvate reductase A compare
BWI76_RS03045 +0.6 0.8 hypothetical protein compare
BWI76_RS08600 +0.6 2.4 3-deoxy-7-phosphoheptulonate synthase compare
BWI76_RS16910 +0.6 1.6 2-keto-4-pentenoate hydratase compare
BWI76_RS27620 +0.6 1.6 hypothetical protein compare
BWI76_RS13415 +0.6 1.3 spermidine/putrescine ABC transporter permease compare
BWI76_RS18125 +0.6 1.4 murein DD-endopeptidase MepM compare
BWI76_RS02940 +0.6 3.3 RpiR family transcriptional regulator compare
BWI76_RS15030 +0.6 1.3 ABC transporter compare
BWI76_RS19755 +0.6 2.9 fructuronate reductase compare
BWI76_RS10570 +0.6 1.7 cysteine ABC transporter substrate-binding protein compare
BWI76_RS06510 +0.6 2.2 BolA family transcriptional regulator compare
BWI76_RS12345 +0.6 2.2 nitrite transporter compare
BWI76_RS06880 +0.6 1.0 biopolymer transport protein ExbD/TolR compare
BWI76_RS13585 +0.6 1.8 4-oxalocrotonate tautomerase compare
BWI76_RS24795 +0.6 3.1 hypothetical protein compare
BWI76_RS04855 +0.6 1.9 regulatory protein AmpE compare
BWI76_RS20925 +0.5 2.3 peptidase M48 compare
BWI76_RS11390 +0.5 2.2 iron dicitrate transport regulator FecR compare
BWI76_RS12040 +0.5 0.8 hypothetical protein compare
BWI76_RS22450 +0.5 1.5 selenoprotein W-related protein compare
BWI76_RS09335 +0.5 0.8 baseplate assembly protein W compare
BWI76_RS15965 +0.5 2.7 MFS transporter compare
BWI76_RS22850 +0.5 1.7 tRNA pseudouridine synthase TruC compare
BWI76_RS27455 +0.5 1.0 DUF805 domain-containing protein compare
BWI76_RS14460 +0.5 1.7 MurR/RpiR family transcriptional regulator compare
BWI76_RS10450 +0.5 1.8 tRNA-Tyr compare
BWI76_RS13150 +0.5 1.5 carnitine operon protein CaiE compare
BWI76_RS10540 +0.5 2.4 allantoinase compare
BWI76_RS06265 +0.5 1.9 antibiotic biosynthesis monooxygenase compare
BWI76_RS22350 +0.5 1.6 hydrogenase nickel incorporation protein HypB compare
BWI76_RS21325 +0.5 1.1 hypothetical protein compare
BWI76_RS04600 +0.5 2.4 inner membrane protein compare
BWI76_RS23000 +0.5 1.8 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase compare
BWI76_RS13785 +0.5 0.9 ABC transporter permease compare
BWI76_RS22815 +0.5 4.1 hybrid sensor histidine kinase/response regulator compare
BWI76_RS05070 +0.5 1.0 type II secretion system protein GspH compare
BWI76_RS02870 +0.5 1.8 hypothetical protein compare
BWI76_RS16980 +0.5 1.9 bifunctional cysteine desulfurase/selenocysteine lyase compare
BWI76_RS13085 +0.5 2.2 bifunctional oxepin-CoA hydrolase/3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase compare
BWI76_RS07255 +0.5 1.2 hypothetical protein compare
BWI76_RS13970 +0.5 1.1 ABC transporter compare
BWI76_RS27635 +0.5 1.2 AraC family transcriptional regulator compare
BWI76_RS19790 +0.5 2.5 putative binding-protein-dependent transporter compare
BWI76_RS18725 +0.5 2.4 hypothetical protein compare
BWI76_RS08640 +0.5 1.2 multidrug efflux pump-associated protein, AcrZ family compare
BWI76_RS25300 +0.5 1.6 hybrid sensor histidine kinase/response regulator compare
BWI76_RS09155 +0.5 2.1 undecaprenyl-diphosphatase compare
BWI76_RS20310 +0.5 0.8 hypothetical protein compare
BWI76_RS07470 +0.5 1.1 MBL fold metallo-hydrolase compare
BWI76_RS21715 +0.5 1.4 transcriptional regulator compare
BWI76_RS10295 +0.5 1.7 short chain dehydrogenase/reductase family oxidoreductase compare
BWI76_RS18410 +0.5 1.4 drug/metabolite exporter YedA compare
BWI76_RS26470 +0.5 2.0 4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase compare
BWI76_RS13610 +0.5 2.1 sugar transporter compare
BWI76_RS15095 +0.5 1.3 isochorismatase compare
BWI76_RS08985 +0.5 1.7 threonine/homoserine exporter RhtA compare
BWI76_RS05045 +0.5 1.1 general secretion pathway protein GspM compare
BWI76_RS13755 +0.5 0.7 hypothetical protein compare
BWI76_RS20050 +0.5 0.9 hypothetical protein compare
BWI76_RS04975 +0.5 1.9 PTS fructose subfamily transporter subunit IIA compare
BWI76_RS03195 +0.5 1.9 P4 phage protein compare
BWI76_RS13420 +0.5 1.0 ABC transporter permease compare
BWI76_RS23060 +0.5 2.0 cobalt-precorrin-4 C(11)-methyltransferase compare
BWI76_RS23035 +0.5 2.8 precorrin-2 C(20)-methyltransferase compare
BWI76_RS12590 +0.5 2.2 helix-turn-helix-type transcriptional regulator compare
BWI76_RS09540 +0.5 1.7 hypothetical protein compare
BWI76_RS06335 +0.5 1.4 nucleoside-specific channel-forming protein Tsx compare
BWI76_RS14510 +0.5 1.0 MFS transporter compare
BWI76_RS05790 +0.5 1.0 phage DNA-binding protein compare
BWI76_RS10500 +0.5 1.1 flavoprotein monooxygenase compare
BWI76_RS17405 +0.5 1.5 cation transport regulator compare
BWI76_RS13405 +0.5 1.7 spermidine/putrescine ABC transporter substrate-binding protein compare
BWI76_RS10855 +0.5 1.8 RND family efflux transporter MFP subunit compare
BWI76_RS12520 +0.5 2.0 hypothetical protein compare
BWI76_RS16810 +0.5 1.8 RpiR family transcriptional regulator compare
BWI76_RS01325 +0.5 1.4 twin-arginine translocase subunit TatB compare
BWI76_RS01560 +0.5 1.8 Rsd/AlgQ family anti-sigma factor compare
BWI76_RS12385 +0.5 1.6 DNA polymerase V subunit UmuC compare
BWI76_RS16200 +0.5 0.9 NAD(P) transhydrogenase subunit beta compare
BWI76_RS14840 +0.5 2.3 hypothetical protein compare
BWI76_RS16225 +0.5 1.8 arginine:ornithine antiporter compare
BWI76_RS20675 +0.5 1.3 GMP synthase compare
BWI76_RS04580 +0.5 1.8 L-ribulose-5-phosphate 4-epimerase compare
BWI76_RS18225 +0.5 1.9 universal stress protein C compare
BWI76_RS05410 +0.5 2.0 2,5-didehydrogluconate reductase B compare
BWI76_RS00680 +0.5 2.0 Rhamnulokinase (EC 2.7.1.5) (from data) compare
BWI76_RS05975 +0.5 2.0 ABC transporter ATP-binding protein compare
BWI76_RS11165 +0.5 1.5 beta-N-acetylhexosaminidase compare
BWI76_RS13370 +0.5 1.2 hypothetical protein compare
BWI76_RS22855 +0.5 1.2 hypothetical protein compare
BWI76_RS14105 +0.5 2.3 NADH:ubiquinone reductase (Na(+)-transporting) subunit E compare
BWI76_RS14480 +0.5 2.5 hypothetical protein compare
BWI76_RS21340 +0.5 1.3 SoxR reducing system protein RseC compare
BWI76_RS08350 +0.5 0.9 carboxylase compare
BWI76_RS14930 +0.5 1.4 hypothetical protein compare
BWI76_RS12485 +0.5 1.0 TyrR family transcriptional regulator compare
BWI76_RS06100 +0.5 1.9 isochorismatase family protein compare
BWI76_RS25400 +0.4 2.0 L(+)-tartrate dehydratase subunit alpha compare
BWI76_RS18585 +0.4 2.7 two-component sensor histidine kinase compare
BWI76_RS20215 +0.4 2.2 transcriptional regulator compare
BWI76_RS00715 +0.4 1.3 two-component sensor histidine kinase compare
BWI76_RS13215 +0.4 0.8 type I glyceraldehyde-3-phosphate dehydrogenase compare
BWI76_RS01930 +0.4 1.4 acid phosphatase/phosphotransferase compare
BWI76_RS22430 +0.4 1.8 manganese/iron transporter ATP-binding protein compare
BWI76_RS25545 +0.4 1.0 hypothetical protein compare
BWI76_RS16335 +0.4 1.0 division septum protein Blr compare
BWI76_RS06330 +0.4 1.6 DNA-binding transcriptional regulator compare
BWI76_RS01330 +0.4 1.3 twin-arginine translocase subunit TatC compare
BWI76_RS09250 +0.4 1.5 hypothetical protein compare


Specific Phenotypes

None in this experiment

For Klebsiella michiganensis M5al in carbon source experiments

For carbon source Sodium pyruvate across organisms