Experiment set5IT047 for Methanococcus maripaludis S2

Compare to:

H2 McCas- cells grown in liquid medium with neomycin

200 most important genes:

  gene name fitness t score description  
MMP_RS06525 -3.7 -1.4 YciI family protein compare
MMP_RS03445 -2.7 -1.0 methanogenesis marker 17 protein compare
MMP_RS07605 -2.3 -1.6 diadenylate cyclase compare
MMP_RS01500 -2.3 -1.3 CBS domain-containing protein compare
MMP_RS07355 -2.2 -0.8 transcription factor S compare
MMP_RS02280 -2.2 -0.8 DUF211 domain-containing protein compare
MMP_RS03485 -2.1 -3.5 TIGR00267 family protein compare
MMP_RS03960 -1.8 -1.0 hypothetical protein compare
MMP_RS01100 -1.8 -1.4 ABC transporter ATP-binding protein compare
MMP_RS02010 -1.8 -6.2 PHP domain-containing protein compare
MMP_RS01220 -1.8 -3.3 hypothetical protein compare
MMP_RS06325 -1.8 -1.5 hypothetical protein compare
MMP_RS05555 -1.8 -0.9 DUF4040 domain-containing protein compare
MMP_RS08350 -1.7 -0.9 hypothetical protein compare
MMP_RS06355 -1.5 -1.6 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS03475 -1.5 -0.6 hypothetical protein compare
MMP_RS03390 -1.5 -3.7 malate dehydrogenase compare
MMP_RS01385 -1.5 -0.6 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS01440 -1.5 -5.0 NAAT family transporter compare
MMP_RS01020 -1.5 -1.0 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS01795 -1.5 -1.0 methanogenesis marker 6 protein compare
MMP_RS01175 -1.4 -1.7 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS06350 -1.4 -3.2 HesA/MoeB/ThiF family protein compare
MMP_RS08995 -1.3 -1.2 hypothetical protein compare
MMP_RS06340 -1.3 -3.4 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS08435 -1.2 -1.1 Era-like GTP-binding protein compare
MMP_RS05920 -1.2 -0.4 50S ribosomal protein L37e compare
MMP_RS01445 -1.2 -4.1 hypothetical protein compare
MMP_RS04685 -1.1 -0.8 DUF126 domain-containing protein compare
MMP_RS00295 -1.1 -1.8 gamma carbonic anhydrase family protein compare
MMP_RS01005 -1.1 -0.6 riboflavin synthase compare
MMP_RS05815 -1.1 -1.4 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS00900 -1.1 -1.4 50S ribosomal protein L39e compare
MMP_RS00110 -1.1 -1.1 hypothetical protein compare
MMP_RS00040 -1.1 -2.5 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS07845 -1.1 -0.8 LL-diaminopimelate aminotransferase compare
MMP_RS08360 -1.0 -2.4 hypothetical protein compare
MMP_RS01840 -1.0 -3.4 TIGR00289 family protein compare
MMP_RS03465 -1.0 -0.7 adenine phosphoribosyltransferase compare
MMP_RS08445 -1.0 -1.7 DUF2099 family protein compare
MMP_RS08310 -1.0 -1.2 TMEM165/GDT1 family protein compare
MMP_RS05425 -1.0 -1.9 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS00300 -1.0 -0.4 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS05280 -1.0 -4.5 COG1361 S-layer family protein compare
MMP_RS02875 -1.0 -3.8 chorismate pyruvate-lyase family protein compare
MMP_RS06975 -0.9 -1.0 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS05540 -0.9 -2.1 hypothetical protein compare
MMP_RS01650 -0.9 -0.6 sulfurtransferase TusA family protein compare
MMP_RS00520 -0.9 -0.6 RNA polymerase Rpb4 family protein compare
MMP_RS08500 -0.9 -2.6 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMP_RS08335 -0.9 -2.8 NADH-quinone oxidoreductase subunit B family protein compare
MMP_RS06895 -0.9 -0.8 selenocysteine-specific translation elongation factor compare
MMP_RS01380 -0.9 -1.5 PHP domain-containing protein compare
MMP_RS01685 -0.9 -1.4 indolepyruvate oxidoreductase subunit beta compare
MMP_RS00695 -0.9 -0.4 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS04875 -0.8 -2.0 energy-converting hydrogenase B subunit P compare
MMP_RS01610 -0.8 -0.8 hypothetical protein compare
MMP_RS01755 -0.8 -0.6 DUF2097 domain-containing protein compare
MMP_RS06105 -0.8 -2.8 hydrogenase maturation peptidase HycI compare
MMP_RS03300 -0.8 -0.6 TOBE domain-containing protein compare
MMP_RS08215 -0.8 -1.2 DUF483 domain-containing protein compare
MMP_RS07525 -0.8 -2.6 4Fe-4S binding protein compare
MMP_RS05765 -0.8 -2.6 M42 family metallopeptidase compare
MMP_RS01225 -0.7 -1.5 DUF5379 domain-containing protein compare
MMP_RS01085 -0.7 -1.1 hypothetical protein compare
MMP_RS07365 -0.7 -3.4 2-phosphoglycerate kinase compare
MMP_RS07955 -0.7 -1.4 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS03095 -0.7 -1.4 diphthine synthase compare
MMP_RS05865 -0.7 -1.8 hypothetical protein compare
MMP_RS06630 -0.7 -0.4 UPF0058 family protein compare
MMP_RS03155 -0.7 -2.2 precorrin-6A reductase compare
MMP_RS02235 -0.7 -3.1 CBS domain-containing protein compare
MMP_RS05850 -0.7 -1.5 Ldh family oxidoreductase compare
MMP_RS08725 -0.7 -1.3 Ni/Fe hydrogenase subunit alpha compare
MMP_RS05910 -0.7 -1.2 cell division ATPase MinD compare
MMP_RS06495 -0.7 -1.7 YkgJ family cysteine cluster protein compare
MMP_RS08365 -0.7 -1.7 energy conserving hydrogenase EhbF compare
MMP_RS04055 -0.7 -0.8 hypothetical protein compare
MMP_RS07545 -0.6 -0.5 HTH domain-containing protein compare
MMP_RS05110 -0.6 -2.0 16S ribosomal RNA methyltransferase A compare
MMP_RS00750 -0.6 -0.6 fumarate hydratase compare
MMP_RS07540 -0.6 -1.1 CBS domain-containing protein compare
MMP_RS06005 -0.6 -1.6 heavy-metal-associated domain-containing protein compare
MMP_RS07185 -0.6 -3.0 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS02470 -0.6 -0.6 helix-turn-helix transcriptional regulator compare
MMP_RS08590 -0.6 -1.9 flagellin compare
MMP_RS01965 -0.6 -1.8 DUF1616 domain-containing protein compare
MMP_RS02900 -0.6 -0.2 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS06870 -0.6 -2.3 DedA family protein compare
MMP_RS08690 -0.6 -2.8 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 compare
MMP_RS05460 -0.6 -3.3 YcaO-related McrA-glycine thioamidation protein compare
MMP_RS01365 -0.6 -1.1 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS00455 -0.6 -2.5 orotate phosphoribosyltransferase-like protein compare
MMP_RS04305 -0.6 -1.1 hypothetical protein compare
MMP_RS03305 -0.6 -1.9 winged helix-turn-helix domain-containing protein compare
MMP_RS03015 -0.6 -1.9 GTP 3' 8-cyclase MoaA compare
MMP_RS04190 -0.6 -2.8 hypothetical protein compare
MMP_RS03520 -0.6 -1.0 YwbE family protein compare
MMP_RS08455 -0.6 -1.7 multiprotein bridging factor aMBF1 compare
MMP_RS04610 -0.6 -1.3 Dabb family protein compare
MMP_RS00830 -0.6 -1.2 purine phosphoribosyltransferase family protein compare
MMP_RS01985 -0.6 -1.8 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS02130 -0.6 -2.5 zinc metalloprotease HtpX compare
MMP_RS02550 -0.6 -2.2 helix-turn-helix transcriptional regulator compare
MMP_RS02245 -0.6 -0.8 hypothetical protein compare
MMP_RS02020 -0.6 -2.1 gamma-glutamylcyclotransferase compare
MMP_RS07600 -0.6 -0.5 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS02805 -0.5 -0.5 HEPN domain-containing protein compare
MMP_RS01720 -0.5 -0.8 replication factor C large subunit compare
MMP_RS01370 -0.5 -2.5 acetate--CoA ligase family protein compare
MMP_RS08320 -0.5 -1.1 molybdopterin molybdotransferase MoeA compare
MMP_RS01330 -0.5 -3.4 DHH family phosphoesterase compare
MMP_RS02745 -0.5 -0.9 hypothetical protein compare
MMP_RS00675 -0.5 -0.4 nitroreductase family protein compare
MMP_RS05420 -0.5 -1.2 DUF61 family protein compare
MMP_RS06435 -0.5 -1.9 CBS domain-containing protein compare
MMP_RS01545 -0.5 -0.2 CBS domain-containing protein compare
MMP_RS01075 -0.5 -0.7 hypothetical protein compare
MMP_RS01460 -0.5 -1.4 hypothetical protein compare
MMP_RS03225 -0.5 -1.5 acetolactate decarboxylase compare
MMP_RS00395 -0.5 -0.7 MGMT family protein compare
MMP_RS07925 -0.5 -1.6 haloacid dehalogenase compare
MMP_RS01415 -0.5 -1.4 DUF2067 domain-containing protein compare
MMP_RS01830 -0.5 -0.5 tRNA-Val compare
MMP_RS05790 -0.5 -2.1 HDIG domain-containing protein compare
MMP_RS06530 -0.5 -1.6 bifunctional hexulose-6-phosphate synthase/ribonuclease regulator compare
MMP_RS01700 -0.5 -0.2 dihydroxy-acid dehydratase compare
MMP_RS02230 -0.5 -2.4 sodium-dependent transporter compare
MMP_RS00770 -0.5 -1.3 hypothetical protein compare
MMP_RS04125 -0.5 -0.9 TetR/AcrR family transcriptional regulator compare
MMP_RS00965 -0.4 -0.7 hypothetical protein compare
MMP_RS03965 -0.4 -0.9 hypothetical protein compare
MMP_RS03035 -0.4 -0.7 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS02045 -0.4 -0.6 tRNA-Met compare
MMP_RS03440 -0.4 -0.5 MoaD/ThiS family protein compare
MMP_RS05550 -0.4 -0.2 cation:proton antiporter compare
MMP_RS07970 -0.4 -1.1 hypothetical protein compare
MMP_RS08655 -0.4 -2.3 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS07090 -0.4 -1.6 tRNA (adenine-N1)-methyltransferase compare
MMP_RS06175 -0.4 -1.3 winged helix-turn-helix transcriptional regulator compare
MMP_RS06335 -0.4 -1.2 HAD family hydrolase compare
MMP_RS07895 -0.4 -0.9 cytochrome c compare
MMP_RS01915 -0.4 -1.4 DUF354 domain-containing protein compare
MMP_RS01450 -0.4 -1.9 tRNA pseudouridine(38-40) synthase TruA compare
MMP_RS04690 -0.4 -0.8 class III signal peptide-containing protein compare
MMP_RS06680 -0.4 -2.3 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS07750 -0.4 -0.8 DUF357 domain-containing protein compare
MMP_RS04775 -0.4 -0.5 adenosylhomocysteinase compare
MMP_RS01375 -0.4 -2.7 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase compare
MMP_RS03140 -0.4 -1.6 hypothetical protein compare
MMP_RS08440 -0.4 -0.6 cell division protein SepF compare
MMP_RS00530 -0.4 -1.5 tRNA pseudouridine(54/55) synthase Pus10 compare
MMP_RS02880 -0.4 -2.3 AmmeMemoRadiSam system radical SAM enzyme compare
MMP_RS06440 -0.4 -1.5 CBS domain-containing protein compare
MMP_RS07635 -0.4 -0.9 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS02690 -0.4 -1.4 FmdE family protein compare
MMP_RS07710 -0.4 -1.8 cell division protein FtsZ compare
MMP_RS08390 -0.4 -1.3 DUF5400 domain-containing protein compare
MMP_RS08090 -0.4 -1.2 hypothetical protein compare
MMP_RS06365 -0.4 -0.7 hypothetical protein compare
MMP_RS06200 -0.4 -1.7 M24 family metallopeptidase compare
MMP_RS06250 -0.4 -1.6 hypothetical protein compare
MMP_RS02540 -0.4 -1.5 DUF2283 domain-containing protein compare
MMP_RS04945 -0.4 -1.2 hypothetical protein compare
MMP_RS06300 -0.4 -2.0 ABC transporter substrate-binding protein compare
MMP_RS02370 -0.4 -1.2 NifB/NifX family molybdenum-iron cluster-binding protein compare
MMP_RS07685 -0.4 -1.4 TIGR01212 family radical SAM protein compare
MMP_RS08840 -0.4 -2.1 class I SAM-dependent methyltransferase compare
MMP_RS08240 -0.4 -1.5 methanogenesis marker 16 metalloprotein compare
MMP_RS02345 -0.4 -0.5 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS05315 -0.4 -0.6 hypothetical protein compare
MMP_RS07645 -0.4 -1.1 aldehyde dehydrogenase family protein compare
MMP_RS04265 -0.4 -0.8 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS05900 -0.4 -1.7 tetratricopeptide repeat protein compare
MMP_RS01640 -0.3 -1.4 2-oxoacid:acceptor oxidoreductase subunit alpha compare
MMP_RS02100 -0.3 -1.0 metallophosphoesterase compare
MMP_RS05435 -0.3 -1.5 5'/3'-nucleotidase SurE compare
MMP_RS06980 -0.3 -1.4 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS01195 -0.3 -0.4 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS05990 -0.3 -1.2 DsrE family protein compare
MMP_RS06920 -0.3 -2.1 AAA family ATPase compare
MMP_RS03670 -0.3 -1.2 DUF1890 domain-containing protein compare
MMP_RS04255 -0.3 -1.7 coenzyme F420 hydrogenase subunit beta compare
MMP_RS02320 -0.3 -1.6 glutamate-cysteine ligase family protein compare
MMP_RS03490 -0.3 -0.5 DUF2115 domain-containing protein compare
MMP_RS01485 -0.3 -1.7 right-handed parallel beta-helix repeat-containing protein compare
MMP_RS06015 -0.3 -1.1 flavodoxin family protein compare
MMP_RS01115 -0.3 -1.3 molybdopterin molybdotransferase MoeA compare
MMP_RS04320 -0.3 -2.2 uroporphyrinogen decarboxylase family protein compare
MMP_RS06485 -0.3 -0.3 zinc ribbon domain-containing protein compare
MMP_RS06190 -0.3 -1.6 tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO compare
MMP_RS08200 -0.3 -2.3 archaeosine synthase subunit alpha compare
MMP_RS04605 -0.3 -0.7 cobalt ECF transporter T component CbiQ compare
MMP_RS06270 -0.3 -0.7 TIGR00300 family protein compare
MMP_RS06375 -0.3 -1.3 ATP-dependent sacrificial sulfur transferase LarE compare
MMP_RS03835 -0.3 -1.9 MATE family efflux transporter compare
MMP_RS06670 -0.3 -0.5 glucose-6-phosphate isomerase compare
MMP_RS05950 -0.3 -1.4 nickel-dependent hydrogenase large subunit compare
MMP_RS05160 -0.3 -1.5 cupredoxin family copper-binding protein compare
MMP_RS05515 -0.3 -0.6 cyclic pyranopterin monophosphate synthase MoaC compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in natural competence experiments

For natural competence Neomycin trisulfate salt hydrate across organisms