Experiment set5IT047 for Methanococcus maripaludis S2

Compare to:

H2 McCas- cells grown in liquid medium with neomycin

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS07620 +9.5 4.2 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS07555 +8.2 11.2 monovalent cation/H+ antiporter subunit E compare
MMP_RS07615 +7.8 3.1 energy-coupling factor ABC transporter permease compare
MMP_RS03700 +7.3 25.5 sodium:proton antiporter compare
MMP_RS03535 +6.7 5.3 helix-turn-helix transcriptional regulator compare
MMP_RS02355 +5.6 3.6 30S ribosomal protein S27ae compare
MMP_RS05445 +5.5 6.3 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS05450 +5.5 3.3 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS05925 +4.9 3.8 small nuclear ribonucleoprotein compare
MMP_RS02800 +4.7 3.2 nucleotidyltransferase domain-containing protein compare
MMP_RS03540 +4.2 2.9 DUF2178 domain-containing protein compare
MMP_RS02475 +3.0 2.1 hypothetical protein compare
MMP_RS06295 +3.0 10.3 methanogenesis marker 14 protein compare
MMP_RS09035 +2.5 3.3 hypothetical protein compare
MMP_RS05145 +2.3 4.2 hypothetical protein compare
MMP_RS00985 +2.1 4.8 CDC48 family AAA ATPase compare
MMP_RS05250 +1.9 2.1 NFYB/HAP3 family transcription factor subunit compare
MMP_RS08370 +1.7 1.4 cation:proton antiporter subunit C compare
MMP_RS08650 +1.6 2.9 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS00305 +1.6 1.5 phosphoribosyl-ATP diphosphatase compare
MMP_RS02480 +1.6 2.9 hypothetical protein compare
MMP_RS04890 +1.6 1.3 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS07730 +1.5 2.2 pyruvate synthase subunit beta compare
MMP_RS07005 +1.5 0.7 4Fe-4S binding protein compare
MMP_RS00335 +1.4 4.9 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMP_RS03205 +1.3 1.2 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS01665 +1.3 3.5 DUF2111 domain-containing protein compare
MMP_RS02240 +1.3 3.4 methanogenesis marker 7 protein compare
MMP_RS08595 +1.3 1.4 flagellar protein C compare
MMP_RS02340 +1.2 1.1 DNA-directed RNA polymerase subunit E'' compare
MMP_RS08720 +1.2 0.8 4Fe-4S binding protein compare
MMP_RS05845 +1.2 1.2 tRNA-intron lyase compare
MMP_RS00310 +1.2 1.8 CBS domain-containing protein compare
MMP_RS06940 +1.1 2.4 polyprenyl diphosphate synthase compare
MMP_RS04520 +1.1 1.6 nucleoside deaminase compare
MMP_RS02175 +1.1 0.9 DUF1611 domain-containing protein compare
MMP_RS03600 +1.1 1.7 triose-phosphate isomerase compare
MMP_RS06625 +1.1 1.2 DNA primase compare
MMP_RS04710 +1.1 0.7 hypothetical protein compare
MMP_RS03020 +1.1 2.7 peptidylprolyl isomerase compare
MMP_RS00945 +1.1 1.1 PadR family transcriptional regulator compare
MMP_RS07385 +1.0 2.1 protein translocase SEC61 complex subunit gamma compare
MMP_RS03775 +1.0 3.0 4Fe-4S dicluster domain-containing protein compare
MMP_RS07390 +1.0 1.3 cell division protein FtsZ compare
MMP_RS08635 +1.0 0.7 UbiA family prenyltransferase compare
MMP_RS06475 +1.0 1.6 FAD-dependent oxidoreductase compare
MMP_RS01525 +1.0 1.5 nucleoside-diphosphate kinase compare
MMP_RS09020 +1.0 0.6 hypothetical protein compare
MMP_RS06400 +1.0 0.6 4Fe-4S binding protein compare
MMP_RS02145 +1.0 2.3 winged helix-turn-helix transcriptional regulator compare
MMP_RS02450 +1.0 1.5 hypothetical protein compare
MMP_RS03315 +0.9 0.5 ferrous iron transport protein A compare
MMP_RS06155 +0.9 0.9 DUF4186 domain-containing protein compare
MMP_RS04615 +0.9 1.5 PDGLE domain-containing protein compare
MMP_RS00800 +0.8 2.2 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS01960 +0.8 0.6 hypothetical protein compare
MMP_RS04780 +0.8 1.4 ribonuclease P compare
MMP_RS00325 +0.8 0.8 RNA-binding protein compare
MMP_RS03640 +0.8 1.0 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS09055 +0.8 0.8 CAP domain-containing protein compare
MMP_RS07725 +0.8 1.9 4Fe-4S dicluster domain-containing protein compare
MMP_RS06885 +0.7 1.3 50S ribosome-binding GTPase compare
MMP_RS06600 +0.7 0.9 class III signal peptide-containing protein compare
MMP_RS03585 +0.7 1.7 Hsp20/alpha crystallin family protein compare
MMP_RS03025 +0.7 1.4 molybdenum cofactor guanylyltransferase compare
MMP_RS05265 +0.7 1.0 2-isopropylmalate synthase compare
MMP_RS08675 +0.7 1.6 class III signal peptide-containing protein compare
MMP_RS04620 +0.7 1.7 cobalt transporter CbiM compare
MMP_RS04145 +0.7 1.2 hypothetical protein compare
MMP_RS06230 +0.7 0.8 helix-turn-helix domain-containing protein compare
MMP_RS02985 +0.7 1.5 hypothetical protein compare
MMP_RS06285 +0.6 1.1 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS05955 +0.6 0.7 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS01600 +0.6 0.7 50S ribosomal protein L15e compare
MMP_RS00825 +0.6 1.2 fumarylacetoacetate hydrolase family protein compare
MMP_RS01905 +0.6 2.5 glycosyltransferase compare
MMP_RS01325 +0.6 1.0 dihydroneopterin aldolase family protein compare
MMP_RS01955 +0.6 1.2 hypothetical protein compare
MMP_RS08300 +0.6 0.4 metal-sulfur cluster assembly factor compare
MMP_RS08580 +0.6 1.2 flagellin compare
MMP_RS05830 +0.6 1.5 peptidyl-prolyl cis-trans isomerase compare
MMP_RS07765 +0.6 4.8 sodium:alanine symporter family protein compare
MMP_RS07755 +0.6 0.4 DUF555 domain-containing protein compare
MMP_RS07875 +0.6 1.9 hypothetical protein compare
MMP_RS03580 +0.6 1.2 signal recognition particle-docking protein FtsY compare
MMP_RS06110 +0.6 1.0 ATP-dependent protease LonB compare
MMP_RS06590 +0.6 1.2 GNAT family N-acetyltransferase compare
MMP_RS01155 +0.6 2.6 XRE family transcriptional regulator compare
MMP_RS02790 +0.6 0.6 class III signal peptide-containing protein compare
MMP_RS00685 +0.6 0.9 2-phospho-L-lactate guanylyltransferase compare
MMP_RS09050 +0.6 1.7 CAP domain-containing protein compare
MMP_RS00280 +0.6 3.0 DUF2118 domain-containing protein compare
MMP_RS03125 +0.6 1.4 cell division ATPase MinD compare
MMP_RS06140 +0.6 2.1 radical SAM protein compare
MMP_RS03615 +0.6 2.5 4Fe-4S binding protein compare
MMP_RS06900 +0.6 0.9 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS01890 +0.6 0.9 nucleotide sugar dehydrogenase compare
MMP_RS04015 +0.5 1.3 hypothetical protein compare
MMP_RS02255 +0.5 1.9 hypothetical protein compare
MMP_RS06170 +0.5 1.8 ABC transporter ATP-binding protein compare
MMP_RS01775 +0.5 0.9 TIGR00297 family protein compare
MMP_RS08410 +0.5 1.3 DUF169 domain-containing protein compare
MMP_RS06515 +0.5 0.6 UPF0489 family protein compare
MMP_RS08855 +0.5 1.8 hypothetical protein compare
MMP_RS08615 +0.5 0.7 flagellar protein G compare
MMP_RS05835 +0.5 0.4 secondary thiamine-phosphate synthase enzyme YjbQ compare
MMP_RS06035 +0.5 3.0 glycosyltransferase family 2 protein compare
MMP_RS06910 +0.5 2.4 RlmF-related methyltransferase compare
MMP_RS05020 +0.5 1.1 hypothetical protein compare
MMP_RS01540 +0.5 0.7 DUF504 domain-containing protein compare
MMP_RS06925 +0.5 0.6 ribonuclease VapC4 compare
MMP_RS02110 +0.5 0.6 hypothetical protein compare
MMP_RS00570 +0.5 1.0 protein-L-isoaspartate O-methyltransferase compare
MMP_RS01310 +0.5 2.9 hypothetical protein compare
MMP_RS06610 +0.5 1.6 DUF2334 domain-containing protein compare
MMP_RS00150 +0.5 2.2 AAA family ATPase compare
MMP_RS03385 +0.5 0.4 cation diffusion facilitator family transporter compare
MMP_RS02455 +0.5 1.9 hypothetical protein compare
MMP_RS05825 +0.5 1.3 peptidyl-prolyl cis-trans isomerase compare
MMP_RS04020 +0.5 1.3 hypothetical protein compare
MMP_RS03565 +0.5 2.1 uracil phosphoribosyltransferase compare
MMP_RS03215 +0.5 2.0 MBL fold metallo-hydrolase compare
MMP_RS01110 +0.5 1.1 FmdE family protein compare
MMP_RS04050 +0.5 1.4 hypothetical protein compare
MMP_RS07380 +0.4 0.6 transcription elongation factor Spt5 compare
MMP_RS05150 +0.4 1.7 hypothetical protein compare
MMP_RS00545 +0.4 1.5 XRE family transcriptional regulator compare
MMP_RS02645 +0.4 2.2 ArsR family transcriptional regulator compare
MMP_RS05170 +0.4 1.3 lysine exporter LysO family protein compare
MMP_RS01305 +0.4 3.0 hypothetical protein compare
MMP_RS05660 +0.4 1.7 phosphate ABC transporter substrate-binding protein compare
MMP_RS00705 +0.4 1.0 hypothetical protein compare
MMP_RS07200 +0.4 1.2 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS00250 +0.4 3.0 Flp pilus assembly complex ATPase component TadA compare
MMP_RS07420 +0.4 1.7 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS06855 +0.4 2.5 hypothetical protein compare
MMP_RS05035 +0.4 1.7 hypothetical protein compare
MMP_RS07560 +0.4 1.5 prefoldin subunit alpha compare
MMP_RS03320 +0.4 1.0 metal-dependent transcriptional regulator compare
MMP_RS01420 +0.4 0.8 hypothetical protein compare
MMP_RS03350 +0.4 1.1 winged helix-turn-helix domain-containing protein compare
MMP_RS01900 +0.4 1.9 hypothetical protein compare
MMP_RS01910 +0.4 1.2 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS07330 +0.4 3.0 membrane protein compare
MMP_RS04720 +0.4 0.6 DedA family protein compare
MMP_RS00895 +0.4 0.7 hypothetical protein compare
MMP_RS07120 +0.4 2.1 coenzyme F420 hydrogenase subunit alpha compare
MMP_RS06480 +0.4 1.3 ABC transporter substrate-binding protein compare
MMP_RS02495 +0.4 0.7 hypothetical protein compare
MMP_RS07910 +0.4 1.9 NAD(P)H-hydrate dehydratase compare
MMP_RS08175 +0.4 1.5 7-cyano-7-deazaguanine synthase compare
MMP_RS09045 +0.4 2.1 class III signal peptide-containing protein compare
MMP_RS04990 +0.4 1.9 aquaporin family protein compare
MMP_RS03785 +0.4 1.0 cupin domain-containing protein compare
MMP_RS02310 +0.4 0.7 RimK-like ATPgrasp N-terminal domain-containing protein compare
MMP_RS03230 +0.4 1.5 flavodoxin family protein compare
MMP_RS02650 +0.4 1.7 flavodoxin family protein compare
MMP_RS01575 +0.4 1.2 aldolase compare
MMP_RS00240 +0.4 2.3 type II secretion system F family protein compare
MMP_RS08745 +0.4 0.6 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS00080 +0.4 1.1 RecB-family nuclease compare
MMP_RS02675 +0.4 0.5 hypothetical protein compare
MMP_RS03090 +0.4 1.7 cation:proton antiporter compare
MMP_RS07890 +0.4 0.6 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS06715 +0.4 2.0 cache domain-containing protein compare
MMP_RS03340 +0.4 0.3 ABC transporter ATP-binding protein compare
MMP_RS06935 +0.4 1.3 protease complex subunit PrcB family protein compare
MMP_RS03400 +0.4 0.6 archease compare
MMP_RS05255 +0.4 1.7 CBS domain-containing protein compare
MMP_RS05580 +0.4 2.4 glycosyltransferase compare
MMP_RS06745 +0.4 1.1 DUF2119 domain-containing protein compare
MMP_RS08980 +0.4 1.4 hypothetical protein compare
MMP_RS04205 +0.4 1.4 carboxymuconolactone decarboxylase family protein compare
MMP_RS05530 +0.4 1.7 signal peptide peptidase SppA compare
MMP_RS07195 +0.4 1.7 M20 family metallo-hydrolase compare
MMP_RS01725 +0.4 0.8 class I SAM-dependent methyltransferase family protein compare
MMP_RS06165 +0.4 1.8 ABC transporter permease compare
MMP_RS00130 +0.4 0.2 nickel-responsive transcriptional regulator NikR compare
MMP_RS07835 +0.4 0.8 TldD/PmbA family protein compare
MMP_RS03780 +0.4 1.7 4Fe-4S binding protein compare
MMP_RS02740 +0.4 1.0 hypothetical protein compare
MMP_RS08860 +0.4 0.7 MinD/ParA family protein compare
MMP_RS04515 +0.4 2.3 betaine/proline/choline family ABC transporter ATP-binding protein compare
MMP_RS01865 +0.4 0.5 GPR1/FUN34/YaaH family transporter compare
MMP_RS02670 +0.3 1.8 ATP-binding cassette domain-containing protein compare
MMP_RS05235 +0.3 2.0 exodeoxyribonuclease III compare
MMP_RS04035 +0.3 0.5 hypothetical protein compare
MMP_RS01430 +0.3 2.1 mechanosensitive ion channel family protein compare
MMP_RS03245 +0.3 0.7 DNA repair and recombination protein RadB compare
MMP_RS06560 +0.3 2.0 hypothetical protein compare
MMP_RS06840 +0.3 0.3 DNA-directed RNA polymerase subunit N compare
MMP_RS05470 +0.3 1.4 DUF523 and DUF1722 domain-containing protein compare
MMP_RS05945 +0.3 1.2 CBS domain-containing protein compare
MMP_RS03870 +0.3 1.4 purine NTPase compare
MMP_RS04985 +0.3 1.1 DUF2180 family protein compare
MMP_RS00565 +0.3 0.6 CBS domain-containing protein compare
MMP_RS05535 +0.3 1.0 hypothetical protein compare
MMP_RS05510 +0.3 1.7 Rrf2 family transcriptional regulator compare
MMP_RS07115 +0.3 1.3 MBL fold metallo-hydrolase compare
MMP_RS02385 +0.3 1.5 ATP-binding protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in natural competence experiments

For natural competence Neomycin trisulfate salt hydrate across organisms