Experiment set5IT047 for Klebsiella michiganensis M5al

Compare to:

Sodium D,L-Lactate carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS00805 -7.7 -5.3 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS18930 -7.6 -7.0 histidinol-phosphate transaminase compare
BWI76_RS18940 -7.5 -5.2 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS04160 -6.9 -8.2 phosphoserine phosphatase compare
BWI76_RS23920 -6.6 -4.6 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS20350 -6.5 -8.9 amidophosphoribosyltransferase compare
BWI76_RS07070 -6.3 -4.4 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS04255 -6.3 -7.5 threonine synthase compare
BWI76_RS04250 -6.3 -8.6 homoserine kinase compare
BWI76_RS21475 -6.1 -8.0 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS09755 -6.0 -8.2 phosphoserine transaminase compare
BWI76_RS18955 -5.8 -6.0 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS04675 -5.8 -8.0 3-isopropylmalate dehydrogenase compare
BWI76_RS11855 -5.8 -8.3 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS04470 -5.8 -11.0 carbamoyl phosphate synthase large subunit compare
BWI76_RS20895 -5.7 -6.8 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS00835 -5.7 -14.8 phosphoenolpyruvate carboxylase compare
BWI76_RS01655 -5.7 -9.0 homoserine O-succinyltransferase compare
BWI76_RS00785 -5.6 -5.5 cystathionine gamma-synthase compare
BWI76_RS26085 -5.6 -3.9 3-dehydroquinate synthase compare
BWI76_RS10990 -5.6 -3.6 dihydroorotase compare
BWI76_RS04465 -5.6 -5.4 carbamoyl-phosphate synthase small subunit compare
BWI76_RS18950 -5.5 -5.7 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS11860 -5.5 -9.2 anthranilate synthase component I compare
BWI76_RS00980 -5.3 -12.4 PLP-dependent threonine dehydratase compare
BWI76_RS23360 -5.3 -5.1 diaminopimelate decarboxylase compare
BWI76_RS04245 -5.3 -15.2 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS20965 -5.3 -5.9 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS27385 -5.2 -7.2 orotate phosphoribosyltransferase compare
BWI76_RS21265 -5.2 -15.1 phosphoribosylformylglycinamidine synthase compare
BWI76_RS02995 -5.2 -9.0 aspartate carbamoyltransferase compare
BWI76_RS05015 -5.2 -4.7 transcriptional regulator compare
BWI76_RS01615 -5.2 -11.5 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS04645 -5.1 -6.0 3-dehydroquinase compare
BWI76_RS11850 -5.1 -8.9 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS04665 -5.1 -20.1 3-isopropylmalate dehydratase small subunit compare
BWI76_RS00985 -5.1 -7.7 transcriptional regulator IlvY compare
BWI76_RS02815 -5.0 -3.5 fructose-bisphosphatase class I compare
BWI76_RS05835 -5.0 -4.8 gamma-glutamyl-phosphate reductase compare
BWI76_RS17065 -4.9 -11.4 phosphoenolpyruvate synthase compare
BWI76_RS04670 -4.9 -10.3 3-isopropylmalate dehydratase large subunit compare
BWI76_RS18935 -4.9 -9.0 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS03010 -4.9 -7.4 ornithine carbamoyltransferase compare
BWI76_RS00965 -4.8 -2.2 acetolactate synthase 2 small subunit compare
BWI76_RS18925 -4.8 -6.7 histidinol dehydrogenase compare
BWI76_RS18920 -4.8 -4.1 ATP phosphoribosyltransferase compare
BWI76_RS00855 -4.8 -8.9 argininosuccinate lyase compare
BWI76_RS08385 -4.7 -5.6 citrate (Si)-synthase compare
BWI76_RS21465 -4.6 -5.8 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS04685 -4.6 -13.3 putative leucine operon leader peptide compare
BWI76_RS00990 -4.6 -7.2 ketol-acid reductoisomerase compare
BWI76_RS11845 -4.5 -2.0 tryptophan synthase subunit beta compare
BWI76_RS04680 -4.5 -11.2 2-isopropylmalate synthase compare
BWI76_RS25115 -4.5 -6.0 argininosuccinate synthase compare
BWI76_RS07065 -4.4 -6.9 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS22755 -4.4 -10.9 phosphoadenosine phosphosulfate reductase compare
BWI76_RS05840 -4.4 -7.0 glutamate 5-kinase compare
BWI76_RS04240 -4.4 -2.1 thr operon leader peptide compare
BWI76_RS00845 -4.3 -8.1 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS09910 -4.2 -14.4 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS20355 -4.1 -6.2 colicin V production protein compare
BWI76_RS00850 -4.1 -10.8 acetylglutamate kinase compare
BWI76_RS04705 -4.1 -6.7 DNA-binding transcriptional regulator FruR compare
BWI76_RS23220 -4.0 -7.3 amino-acid N-acetyltransferase compare
BWI76_RS24285 -4.0 -7.0 cystathionine beta-lyase compare
BWI76_RS09660 -4.0 -2.7 DNA translocase FtsK compare
BWI76_RS11840 -3.9 -6.9 tryptophan synthase subunit alpha compare
BWI76_RS09760 -3.9 -6.3 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS20435 -3.8 -2.4 chorismate synthase compare
BWI76_RS00975 -3.8 -6.9 dihydroxy-acid dehydratase compare
BWI76_RS22765 -3.8 -14.0 sulfite reductase subunit alpha compare
BWI76_RS27390 -3.8 -5.5 ribonuclease PH compare
BWI76_RS01610 -3.8 -5.3 phosphoribosylamine--glycine ligase compare
BWI76_RS23240 -3.7 -3.6 exonuclease V subunit gamma compare
BWI76_RS23365 -3.6 -8.3 LysR family transcriptional regulator compare
BWI76_RS08395 -3.6 -3.2 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS09645 -3.6 -2.3 thioredoxin-disulfide reductase compare
BWI76_RS22760 -3.6 -9.3 sulfite reductase subunit beta compare
BWI76_RS00400 -3.5 -2.4 glutamine synthetase compare
BWI76_RS11965 -3.5 -4.8 orotidine-5'-phosphate decarboxylase compare
BWI76_RS02530 -3.5 -4.0 tRNA dimethylallyltransferase compare
BWI76_RS00180 -3.4 -2.8 F0F1 ATP synthase subunit epsilon compare
BWI76_RS24900 -3.3 -3.2 DeoR family transcriptional regulator compare
BWI76_RS01185 -3.3 -2.3 adenylate cyclase compare
BWI76_RS02735 -3.3 -6.4 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS27185 -3.1 -13.6 L-lactate/D-lactate permease (from data) conserved
BWI76_RS06185 -3.0 -11.8 shikimate kinase II compare
BWI76_RS01210 -3.0 -2.7 tyrosine recombinase XerC compare
BWI76_RS08405 -3.0 -4.9 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS23230 -3.0 -3.5 exodeoxyribonuclease V subunit beta compare
BWI76_RS05200 -2.8 -4.2 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS20970 -2.6 -2.5 phosphoribosylglycinamide formyltransferase compare
BWI76_RS27190 -2.5 -6.8 transcriptional regulator LldR conserved
BWI76_RS15825 -2.4 -2.0 hypothetical protein compare
BWI76_RS22690 -2.3 -3.9 adenylyl-sulfate kinase compare
BWI76_RS26055 -2.1 -6.7 siroheme synthase compare
BWI76_RS10745 -2.1 -1.8 hypothetical protein compare
BWI76_RS21580 -2.0 -2.6 SsrA-binding protein compare
BWI76_RS20640 -2.0 -6.0 cysteine synthase A compare
BWI76_RS17720 -1.9 -2.2 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS06475 -1.8 -1.8 protoheme IX farnesyltransferase compare
BWI76_RS23885 -1.8 -2.6 2-octaprenylphenol hydroxylase compare
BWI76_RS21370 -1.8 -2.6 ATP-dependent RNA helicase SrmB compare
BWI76_RS22420 -1.7 -3.9 LacI family transcriptional regulator compare
BWI76_RS01200 -1.7 -2.3 diaminopimelate epimerase compare
BWI76_RS21100 -1.7 -2.3 nucleoside-diphosphate kinase compare
BWI76_RS27440 -1.7 -5.0 DNA helicase RecG compare
BWI76_RS15830 -1.7 -2.7 hypothetical protein compare
BWI76_RS15135 -1.6 -5.8 hypothetical protein compare
BWI76_RS03080 -1.6 -3.5 (Fe-S)-cluster assembly protein compare
BWI76_RS25960 -1.6 -4.9 NUDIX hydrolase compare
BWI76_RS08430 -1.6 -3.4 succinate--CoA ligase subunit alpha compare
BWI76_RS08425 -1.6 -5.3 succinyl-CoA ligase subunit beta compare
BWI76_RS09190 -1.5 -4.4 hypothetical protein compare
BWI76_RS16275 -1.5 -2.0 fumarate hydratase FumA compare
BWI76_RS15835 -1.5 -1.2 hypothetical protein compare
BWI76_RS20440 -1.5 -1.4 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS26570 -1.5 -3.4 anion permease compare
BWI76_RS04530 -1.5 -2.3 peptidylprolyl isomerase SurA compare
BWI76_RS23830 -1.5 -6.1 hypothetical protein compare
BWI76_RS00140 -1.4 -1.5 phosphate transport system regulator PhoU compare
BWI76_RS00390 -1.4 -3.4 two-component system sensor histidine kinase NtrB compare
BWI76_RS11435 -1.4 -1.7 hypothetical protein compare
BWI76_RS01350 -1.4 -1.2 NAD(P)H-flavin reductase compare
BWI76_RS19515 -1.4 -3.4 D-lactate dehydrogenase (cytochrome c-553) (EC 1.1.2.5) (from data) compare
BWI76_RS02410 -1.3 -1.8 EF-P beta-lysylation protein EpmB compare
BWI76_RS15955 -1.3 -7.6 transcriptional regulator compare
BWI76_RS17290 -1.3 -5.1 formyltetrahydrofolate deformylase compare
BWI76_RS23480 -1.3 -7.9 EAL domain-containing protein compare
BWI76_RS25320 -1.3 -6.0 glutamate synthase compare
BWI76_RS00960 -1.3 -4.9 acetolactate synthase 2 catalytic subunit compare
BWI76_RS19010 -1.3 -3.0 polysaccharide pyruvyl transferase yvff compare
BWI76_RS25645 -1.2 -6.3 shikimate dehydrogenase compare
BWI76_RS03415 -1.2 -3.6 LacI family transcriptional regulator compare
BWI76_RS25315 -1.2 -7.1 glutamate synthase large subunit compare
BWI76_RS03225 -1.2 -5.5 transcriptional regulator compare
BWI76_RS15650 -1.2 -3.0 gp5 compare
BWI76_RS15810 -1.2 -4.0 hypothetical protein compare
BWI76_RS21200 -1.2 -4.3 aldose epimerase compare
BWI76_RS22085 -1.2 -3.6 L-valine transporter subunit YgaH compare
BWI76_RS08390 -1.1 -3.5 hypothetical protein compare
BWI76_RS22695 -1.1 -5.1 sulfate adenylyltransferase compare
BWI76_RS22805 -1.1 -5.7 GTP diphosphokinase compare
BWI76_RS09635 -1.1 -2.8 amino acid ABC transporter ATP-binding protein compare
BWI76_RS15840 -1.1 -2.1 prophage protein compare
BWI76_RS26000 -1.1 -3.9 aspartate aminotransferase family protein compare
BWI76_RS15760 -1.1 -1.9 hypothetical protein compare
BWI76_RS25335 -1.1 -3.0 stringent starvation protein A compare
BWI76_RS20270 -1.1 -5.5 hypothetical protein compare
BWI76_RS19840 -1.1 -1.4 hypothetical protein compare
BWI76_RS25280 -1.1 -1.9 RNase adaptor protein RapZ compare
BWI76_RS16955 -1.0 -1.6 hypothetical protein compare
BWI76_RS22240 -1.0 -4.6 transcriptional regulator compare
BWI76_RS20995 -1.0 -2.8 RNA degradosome polyphosphate kinase compare
BWI76_RS06680 -1.0 -1.1 hypothetical protein compare
BWI76_RS27075 -1.0 -4.4 IclR family transcriptional regulator compare
BWI76_RS05680 -1.0 -3.2 LacI family transcriptional regulator compare
BWI76_RS26460 -1.0 -4.5 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS05120 -1.0 -5.0 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS15635 -1.0 -2.6 hypothetical protein compare
BWI76_RS06485 -1.0 -1.5 cytochrome o ubiquinol oxidase subunit III compare
BWI76_RS06495 -1.0 -4.9 cytochrome ubiquinol oxidase subunit II compare
BWI76_RS00970 -1.0 -2.2 branched chain amino acid aminotransferase compare
BWI76_RS26175 -1.0 -3.7 DeoR/GlpR family transcriptional regulator compare
BWI76_RS26620 -1.0 -1.2 Fe-S biogenesis protein NfuA compare
BWI76_RS05005 -1.0 -2.5 polynucleotide adenylyltransferase compare
BWI76_RS20910 -1.0 -5.2 glycine cleavage system transcriptional repressor compare
BWI76_RS26390 -1.0 -4.3 cell division protein FtsX compare
BWI76_RS23810 -1.0 -2.2 bifunctional protein-disulfide isomerase/oxidoreductase DsbC compare
BWI76_RS17775 -0.9 -1.7 hypothetical protein compare
BWI76_RS26395 -0.9 -2.0 cell division protein FtsE compare
BWI76_RS00355 -0.9 -2.9 DNA polymerase I compare
BWI76_RS21165 -0.9 -1.7 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS01220 -0.9 -4.2 DNA-dependent helicase II compare
BWI76_RS26890 -0.9 -1.5 hypothetical protein compare
BWI76_RS01775 -0.9 -1.2 hypothetical protein compare
BWI76_RS19730 -0.9 -1.4 1-phosphofructokinase compare
BWI76_RS03105 -0.9 -1.0 myo-inosose-2 dehydratase compare
BWI76_RS05790 -0.9 -1.5 phage DNA-binding protein compare
BWI76_RS06340 -0.9 -1.2 hypothetical protein compare
BWI76_RS20160 -0.9 -2.9 NADH-quinone oxidoreductase subunit H compare
BWI76_RS06560 -0.9 -2.1 7-cyano-7-deazaguanine synthase QueC compare
BWI76_RS15845 -0.9 -1.2 hypothetical protein compare
BWI76_RS04525 -0.9 -1.8 4-hydroxythreonine-4-phosphate dehydrogenase PdxA compare
BWI76_RS11300 -0.9 -1.2 cupin compare
BWI76_RS12145 -0.9 -1.7 hypothetical protein compare
BWI76_RS25425 -0.9 -1.3 arginine repressor compare
BWI76_RS09615 -0.9 -1.9 ATP-dependent Clp protease ATP-binding subunit ClpA compare
BWI76_RS17155 -0.8 -1.8 hypothetical protein compare
BWI76_RS06765 -0.8 -2.9 transcriptional regulator compare
BWI76_RS02610 -0.8 -3.2 transcriptional regulator compare
BWI76_RS20155 -0.8 -1.8 NADH-quinone oxidoreductase subunit I compare
BWI76_RS15685 -0.8 -2.0 hypothetical protein compare
BWI76_RS08605 -0.8 -1.6 phosphoglyceromutase compare
BWI76_RS11580 -0.8 -1.7 L-asparaginase 1 compare
BWI76_RS24850 -0.8 -5.2 DeoR family transcriptional regulator compare
BWI76_RS16315 -0.8 -1.1 SirA-like protein compare
BWI76_RS15705 -0.8 -2.0 putative holin protein compare
BWI76_RS21480 -0.8 -1.8 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS11235 -0.8 -1.1 hypothetical protein compare


Specific Phenotypes

For 3 genes in this experiment

For carbon source Sodium D,L-Lactate in Klebsiella michiganensis M5al

For carbon source Sodium D,L-Lactate across organisms