Experiment set5IT047 for Klebsiella michiganensis M5al

Compare to:

Sodium D,L-Lactate carbon source

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS24575 +2.0 3.5 hypothetical protein compare
BWI76_RS13250 +1.2 2.0 cytochrome b561 compare
BWI76_RS18770 +1.1 1.7 DNA gyrase inhibitor compare
BWI76_RS09080 +1.1 3.3 molybdopterin-synthase adenylyltransferase MoeB compare
BWI76_RS18870 +1.1 2.2 protein NifZ compare
BWI76_RS17975 +1.0 3.6 tail-specific protease compare
BWI76_RS19575 +1.0 3.7 maleylacetoacetate isomerase compare
BWI76_RS20795 +1.0 1.7 ethanolamine catabolic microcompartment shell protein EutN compare
BWI76_RS06910 +1.0 2.1 transcriptional regulator compare
BWI76_RS12780 +0.9 2.6 hypothetical protein compare
BWI76_RS23020 +0.9 2.9 cobalamin biosynthesis protein CbiQ compare
BWI76_RS16000 +0.9 1.7 multidrug transporter subunit MdtI compare
BWI76_RS13970 +0.9 2.0 ABC transporter compare
BWI76_RS01995 +0.9 1.4 AraC family transcriptional regulator compare
BWI76_RS20720 +0.8 0.6 hypothetical protein compare
BWI76_RS17860 +0.8 1.9 YoaH family protein compare
BWI76_RS15940 +0.8 2.2 DMSO reductase maturation protein DsmD compare
BWI76_RS26440 +0.8 1.6 hypothetical protein compare
BWI76_RS07165 +0.8 2.1 hypothetical protein compare
BWI76_RS08735 +0.7 2.5 Urocanate hydratase (EC 4.2.1.49) (from data) compare
BWI76_RS15150 +0.7 1.7 outer membrane efflux protein compare
BWI76_RS04305 +0.7 0.7 molecular chaperone DnaJ compare
BWI76_RS18070 +0.7 1.4 DNA polymerase III subunit epsilon compare
BWI76_RS16900 +0.7 1.3 4-hydroxy-2-oxovalerate aldolase compare
BWI76_RS16075 +0.7 1.3 oxidoreductase compare
BWI76_RS11520 +0.7 1.1 hypothetical protein compare
BWI76_RS11525 +0.7 2.0 HNH endonuclease compare
BWI76_RS11775 +0.7 2.3 2-deoxy-D-gluconate 3-dehydrogenase compare
BWI76_RS08275 +0.7 1.4 LexA regulated protein compare
BWI76_RS11895 +0.7 1.8 AraC family transcriptional regulator compare
BWI76_RS16895 +0.7 1.6 3-(3-hydroxy-phenyl)propionate transporter MhpT compare
BWI76_RS14510 +0.6 1.6 MFS transporter compare
BWI76_RS09860 +0.6 2.0 hypothetical protein compare
BWI76_RS05810 +0.6 1.1 hypothetical protein compare
BWI76_RS24885 +0.6 0.9 PTS galactitol transporter subunit IIB compare
BWI76_RS20940 +0.6 1.6 uracil/xanthine transporter compare
BWI76_RS05075 +0.6 1.0 type II secretion system protein GspG compare
BWI76_RS08765 +0.6 2.1 8-amino-7-oxononanoate synthase compare
BWI76_RS17570 +0.6 1.9 iron-sulfur-binding protein compare
BWI76_RS12585 +0.6 2.1 transcriptional regulator compare
BWI76_RS13360 +0.6 2.6 benzoate transporter compare
BWI76_RS17315 +0.6 1.9 EamA family transporter compare
BWI76_RS19770 +0.6 1.1 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase compare
BWI76_RS25000 +0.6 0.7 malonate decarboxylase acyl carrier protein compare
BWI76_RS07475 +0.6 0.9 DNA-binding transcriptional regulator RamA compare
BWI76_RS26575 +0.6 1.6 universal stress protein B compare
BWI76_RS00880 +0.6 2.7 membrane protein compare
BWI76_RS14770 +0.6 1.1 PTS IIA 2 domain protein compare
BWI76_RS14955 +0.6 2.6 peptidase M17 leucyl aminopeptidase domain-containing protein compare
BWI76_RS26285 +0.6 1.9 glycerophosphodiester phosphodiesterase compare
BWI76_RS10435 +0.6 2.0 suppressor for copper-sensitivity C compare
BWI76_RS14610 +0.6 1.5 putative hydrolase compare
BWI76_RS24810 +0.6 2.3 hypothetical protein compare
BWI76_RS11170 +0.6 1.1 hypothetical protein compare
BWI76_RS23005 +0.6 2.2 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS23305 +0.6 1.3 NADP(H)-dependent aldo-keto reductase compare
BWI76_RS23375 +0.6 2.5 cupin compare
BWI76_RS09030 +0.6 1.8 transpeptidase compare
BWI76_RS11190 +0.6 2.1 putative TetR/AcrR family transcriptional regulatory protein compare
BWI76_RS24240 +0.6 1.5 hypothetical protein compare
BWI76_RS18755 +0.6 1.0 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS17955 +0.6 1.3 hypothetical protein compare
BWI76_RS09895 +0.6 1.4 aliphatic sulfonates ABC transporter ATP-binding protein compare
BWI76_RS21170 +0.6 2.3 tRNA (cytosine(32)/uridine(32)-2'-O)-methyltransferase TrmJ compare
BWI76_RS11285 +0.6 1.3 transcriptional regulator compare
BWI76_RS06325 +0.6 0.9 hypothetical protein compare
BWI76_RS10760 +0.6 0.9 nitroreductase family protein compare
BWI76_RS05950 +0.6 1.3 polar amino acid ABC transporter inner membrane subunit compare
BWI76_RS24920 +0.6 1.2 YraN family protein compare
BWI76_RS27915 +0.6 1.0 YceK/YidQ family lipoprotein compare
BWI76_RS07260 +0.6 2.0 branched chain amino acid ABC transporter substrate-binding protein compare
BWI76_RS08625 +0.6 2.1 UDP-glucose 4-epimerase GalE compare
BWI76_RS06405 +0.6 0.7 2-dehydropantoate 2-reductase compare
BWI76_RS15965 +0.6 2.4 MFS transporter compare
BWI76_RS21090 +0.6 1.6 cytoskeletal protein RodZ compare
BWI76_RS22975 +0.6 1.4 tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA compare
BWI76_RS00720 +0.6 1.6 DNA-binding response regulator compare
BWI76_RS10060 +0.5 1.1 acylphosphatase compare
BWI76_RS22470 +0.5 1.2 transporter permease compare
BWI76_RS27455 +0.5 1.7 DUF805 domain-containing protein compare
BWI76_RS07540 +0.5 1.9 dipeptide ABC transporter ATP-binding protein DppD compare
BWI76_RS11640 +0.5 3.0 ABC transporter membrane protein compare
BWI76_RS25480 +0.5 1.2 ribonuclease E/G compare
BWI76_RS26505 +0.5 2.0 nickel ABC transporter permease subunit NikB compare
BWI76_RS11490 +0.5 2.5 MltA-interacting protein MipA compare
BWI76_RS18360 +0.5 1.4 aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase family protein compare
BWI76_RS25440 +0.5 1.9 putative barnase inhibitor compare
BWI76_RS16550 +0.5 1.9 tRNA-Val compare
BWI76_RS04560 +0.5 2.3 holo-ACP synthase CitX compare
BWI76_RS13715 +0.5 1.3 2-chlorobenzoate 1 2-dioxygenase electron transfer subunit compare
BWI76_RS05040 +0.5 1.8 type II secretion system protein N compare
BWI76_RS04895 +0.5 1.4 hypothetical protein compare
BWI76_RS03545 +0.5 2.2 QacE family quaternary ammonium compound efflux SMR transporter compare
BWI76_RS14625 +0.5 1.0 protein TolA compare
BWI76_RS22950 +0.5 1.6 membrane protein compare
BWI76_RS14940 +0.5 1.8 hypothetical protein compare
BWI76_RS16050 +0.5 2.4 malonate decarboxylase holo-ACP synthase compare
BWI76_RS14390 +0.5 0.7 hypothetical protein compare
BWI76_RS18650 +0.5 1.6 fimbrial protein compare
BWI76_RS26280 +0.5 1.9 hypothetical protein compare
BWI76_RS12915 +0.5 2.5 4-hydroxyphenylacetate permease compare
BWI76_RS07640 +0.5 0.9 short chain dehydrogenase compare
BWI76_RS07765 +0.5 1.2 thioesterase compare
BWI76_RS15035 +0.5 0.6 metal ABC transporter permease compare
BWI76_RS04700 +0.5 1.4 acetolactate synthase small subunit compare
BWI76_RS18200 +0.5 2.3 copper homeostasis protein CutC compare
BWI76_RS11515 +0.5 0.6 peptide-methionine (R)-S-oxide reductase compare
BWI76_RS21940 +0.5 2.0 SDR family oxidoreductase compare
BWI76_RS06335 +0.5 1.2 nucleoside-specific channel-forming protein Tsx compare
BWI76_RS02225 +0.5 1.9 phosphonate C-P lyase system protein PhnG compare
BWI76_RS11250 +0.5 0.6 spermidine/putrescine ABC transporter permease PotB compare
BWI76_RS16810 +0.5 1.2 RpiR family transcriptional regulator compare
BWI76_RS08705 +0.5 2.4 putative LuxR family regulatory protein compare
BWI76_RS17045 +0.5 0.8 hypothetical protein compare
BWI76_RS02880 +0.5 1.8 membrane protein compare
BWI76_RS11430 +0.5 0.7 lipoprotein compare
BWI76_RS15970 +0.5 2.0 carboxypeptidase M32 compare
BWI76_RS15215 +0.5 0.6 N-acetyltransferase compare
BWI76_RS27745 +0.5 1.5 PTS sugar transporter subunit IIB compare
BWI76_RS13060 +0.5 1.5 glutathione S-transferase compare
BWI76_RS08600 +0.5 2.0 3-deoxy-7-phosphoheptulonate synthase compare
BWI76_RS07865 +0.5 1.4 methylthioribulose 1-phosphate dehydratase compare
BWI76_RS01330 +0.5 1.5 twin-arginine translocase subunit TatC compare
BWI76_RS23125 +0.5 1.1 propanediol dehydratase small subunit compare
BWI76_RS07755 +0.5 1.1 isochorismatase compare
BWI76_RS16115 +0.5 1.9 fumarate hydratase compare
BWI76_RS15345 +0.5 1.5 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase compare
BWI76_RS02705 +0.5 1.5 iron-sulfur cluster repair di-iron protein compare
BWI76_RS04425 +0.5 1.6 oxaloacetate decarboxylase subunit gamma compare
BWI76_RS10650 +0.5 1.5 PTS fructose-like transporter subunit EIIB compare
BWI76_RS09065 +0.5 1.6 sugar phosphatase SupH compare
BWI76_RS17765 +0.5 1.4 hypothetical protein compare
BWI76_RS19860 +0.5 1.6 hypothetical protein compare
BWI76_RS13585 +0.5 1.5 4-oxalocrotonate tautomerase compare
BWI76_RS22940 +0.5 1.7 DNA-binding transcriptional activator FucR compare
BWI76_RS16795 +0.5 1.5 amino acid ABC transporter ATPase compare
BWI76_RS09560 +0.5 0.9 DoxX family membrane protein compare
BWI76_RS25035 +0.4 1.2 malonate transporter subunit MadM compare
BWI76_RS20765 +0.4 2.3 ethanolamine ammonia lyase large subunit compare
BWI76_RS01815 +0.4 1.9 phosphate-starvation-inducible protein PsiE compare
BWI76_RS10400 +0.4 1.5 hypothetical protein compare
BWI76_RS21470 +0.4 1.5 gluconolaconase compare
BWI76_RS21660 +0.4 1.0 antirestriction protein compare
BWI76_RS15795 +0.4 1.8 bacteriophage CII family protein compare
BWI76_RS14575 +0.4 1.3 TENA/THI-4 family protein compare
BWI76_RS21375 +0.4 0.8 autonomous glycyl radical cofactor GrcA compare
BWI76_RS10575 +0.4 0.9 polar amino acid ABC transporter permease compare
BWI76_RS19835 +0.4 2.1 nucleoid-associated protein YejK compare
BWI76_RS13280 +0.4 2.2 LysR family transcriptional regulator compare
BWI76_RS06590 +0.4 1.9 multidrug ABC transporter permease/ATP-binding protein compare
BWI76_RS18585 +0.4 2.1 two-component sensor histidine kinase compare
BWI76_RS21740 +0.4 1.9 transcriptional regulator, LysR family protein compare
BWI76_RS27560 +0.4 1.6 hypothetical protein compare
BWI76_RS18550 +0.4 0.9 tRNA-Asn compare
BWI76_RS17350 +0.4 1.0 DNA-binding response regulator compare
BWI76_RS02570 +0.4 1.7 transcriptional regulator compare
BWI76_RS13330 +0.4 0.9 tellurite resistance methyltransferase TehB compare
BWI76_RS22625 +0.4 1.1 transcriptional regulator compare
BWI76_RS11020 +0.4 2.2 oxidoreductase family, NAD-binding protein compare
BWI76_RS02860 +0.4 0.7 glycine dehydrogenase compare
BWI76_RS09490 +0.4 1.4 DNA-binding response regulator compare
BWI76_RS25195 +0.4 2.5 maltose metabolism regulator compare
BWI76_RS08040 +0.4 0.9 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH compare
BWI76_RS17915 +0.4 1.6 membrane protein compare
BWI76_RS13805 +0.4 1.1 inorganic diphosphatase compare
BWI76_RS09335 +0.4 0.6 baseplate assembly protein W compare
BWI76_RS24945 +0.4 0.7 glutamine amidotransferase compare
BWI76_RS20430 +0.4 1.1 penicillin-insensitive murein endopeptidase compare
BWI76_RS08120 +0.4 2.4 cobalt transporter compare
BWI76_RS08450 +0.4 2.2 fumarate hydratase compare
BWI76_RS13755 +0.4 1.0 hypothetical protein compare
BWI76_RS22815 +0.4 2.6 hybrid sensor histidine kinase/response regulator compare
BWI76_RS26215 +0.4 2.5 glycogen-branching enzyme compare
BWI76_RS15410 +0.4 2.0 N-acetyltransferase compare
BWI76_RS12330 +0.4 1.3 hypothetical protein compare
BWI76_RS00560 +0.4 2.3 hypothetical protein compare
BWI76_RS06165 +0.4 1.5 phosphate starvation-inducible protein PsiF compare
BWI76_RS02855 +0.4 1.5 cytochrome B562 compare
BWI76_RS15120 +0.4 1.6 hypothetical protein compare
BWI76_RS21910 +0.4 0.9 glyoxylate/hydroxypyruvate reductase A compare
BWI76_RS11890 +0.4 1.6 glycosyl hydrolase compare
BWI76_RS09935 +0.4 1.7 paraquat-inducible membrane protein A compare
BWI76_RS01580 +0.4 0.9 hypothetical protein compare
BWI76_RS06885 +0.4 0.7 TonB family protein compare
BWI76_RS26870 +0.4 1.3 dipeptide ABC transporter ATP-binding protein compare
BWI76_RS13050 +0.4 1.1 transcriptional regulator compare
BWI76_RS23690 +0.4 0.8 putative glyoxalase/bleomycin resistance protein/dioxygenase compare
BWI76_RS00740 +0.4 1.1 ribonuclease E activity regulator RraA compare
BWI76_RS25285 +0.4 0.5 HPr family phosphocarrier protein compare
BWI76_RS04260 +0.4 2.0 peroxide stress protein YaaA compare
BWI76_RS27520 +0.4 1.9 sodium/glutamate symporter compare
BWI76_RS21995 +0.4 2.4 transcriptional regulator compare
BWI76_RS16690 +0.4 1.8 peptide ABC transporter permease compare
BWI76_RS13415 +0.4 1.2 spermidine/putrescine ABC transporter permease compare
BWI76_RS03515 +0.4 1.9 hypothetical protein compare
BWI76_RS20735 +0.4 1.9 N-acetylmuramoyl-L-alanine amidase compare
BWI76_RS21245 +0.4 0.9 nitrogen regulatory protein P-II compare
BWI76_RS26630 +0.4 1.6 pimeloyl-[acyl-carrier protein] methyl ester esterase compare
BWI76_RS17525 +0.4 0.7 XshC-Cox1-family protein compare
BWI76_RS16035 +0.4 1.5 biotin-independent malonate decarboxylase subunit beta compare


Specific Phenotypes

For 3 genes in this experiment

For carbon source Sodium D,L-Lactate in Klebsiella michiganensis M5al

For carbon source Sodium D,L-Lactate across organisms