Experiment set5IT046 for Klebsiella michiganensis M5al

Compare to:

Sodium L-Lactate carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS11965 -8.1 -5.6 orotidine-5'-phosphate decarboxylase compare
BWI76_RS04675 -7.6 -5.3 3-isopropylmalate dehydrogenase compare
BWI76_RS18930 -7.0 -4.5 histidinol-phosphate transaminase compare
BWI76_RS20965 -6.9 -5.6 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS18925 -6.9 -6.7 histidinol dehydrogenase compare
BWI76_RS04470 -6.8 -8.1 carbamoyl phosphate synthase large subunit compare
BWI76_RS04465 -6.6 -4.6 carbamoyl-phosphate synthase small subunit compare
BWI76_RS01615 -6.6 -7.9 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS23920 -6.4 -4.4 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS00805 -6.3 -6.2 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS02815 -6.3 -4.3 fructose-bisphosphatase class I compare
BWI76_RS20355 -6.3 -4.5 colicin V production protein compare
BWI76_RS18935 -6.3 -8.3 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS05835 -6.2 -4.3 gamma-glutamyl-phosphate reductase compare
BWI76_RS04670 -6.0 -10.1 3-isopropylmalate dehydratase large subunit compare
BWI76_RS08385 -5.9 -3.3 citrate (Si)-synthase compare
BWI76_RS09760 -5.9 -5.2 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS04255 -5.9 -9.0 threonine synthase compare
BWI76_RS02995 -5.8 -6.8 aspartate carbamoyltransferase compare
BWI76_RS11855 -5.8 -6.4 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS00855 -5.8 -8.8 argininosuccinate lyase compare
BWI76_RS07070 -5.7 -5.5 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS04665 -5.6 -20.2 3-isopropylmalate dehydratase small subunit compare
BWI76_RS21265 -5.6 -14.9 phosphoribosylformylglycinamidine synthase compare
BWI76_RS26085 -5.5 -3.7 3-dehydroquinate synthase compare
BWI76_RS11860 -5.4 -9.6 anthranilate synthase component I compare
BWI76_RS18955 -5.4 -5.1 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS09755 -5.4 -8.6 phosphoserine transaminase compare
BWI76_RS00985 -5.3 -6.3 transcriptional regulator IlvY compare
BWI76_RS23365 -5.3 -7.2 LysR family transcriptional regulator compare
BWI76_RS00845 -5.2 -10.5 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS00980 -5.1 -11.1 PLP-dependent threonine dehydratase compare
BWI76_RS23360 -5.1 -5.0 diaminopimelate decarboxylase compare
BWI76_RS00850 -5.1 -6.9 acetylglutamate kinase compare
BWI76_RS20350 -5.0 -4.7 amidophosphoribosyltransferase compare
BWI76_RS04645 -5.0 -7.3 3-dehydroquinase compare
BWI76_RS04685 -5.0 -11.4 putative leucine operon leader peptide compare
BWI76_RS04250 -5.0 -8.1 homoserine kinase compare
BWI76_RS04245 -5.0 -11.9 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS11840 -5.0 -4.0 tryptophan synthase subunit alpha compare
BWI76_RS11850 -5.0 -7.5 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS04160 -4.9 -7.8 phosphoserine phosphatase compare
BWI76_RS21475 -4.9 -6.4 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS05840 -4.8 -4.4 glutamate 5-kinase compare
BWI76_RS00975 -4.8 -9.0 dihydroxy-acid dehydratase compare
BWI76_RS22690 -4.7 -3.9 adenylyl-sulfate kinase compare
BWI76_RS04705 -4.7 -7.2 DNA-binding transcriptional regulator FruR compare
BWI76_RS00965 -4.7 -1.9 acetolactate synthase 2 small subunit compare
BWI76_RS09910 -4.7 -18.4 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS22755 -4.6 -7.6 phosphoadenosine phosphosulfate reductase compare
BWI76_RS01655 -4.5 -7.7 homoserine O-succinyltransferase compare
BWI76_RS23220 -4.5 -6.3 amino-acid N-acetyltransferase compare
BWI76_RS27195 -4.5 -6.4 alpha-hydroxy-acid oxidizing enzyme compare
BWI76_RS04680 -4.5 -8.8 2-isopropylmalate synthase compare
BWI76_RS25115 -4.5 -7.6 argininosuccinate synthase compare
BWI76_RS00785 -4.5 -6.8 cystathionine gamma-synthase compare
BWI76_RS17065 -4.3 -7.8 phosphoenolpyruvate synthase compare
BWI76_RS18950 -4.3 -6.0 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS20895 -4.2 -5.7 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS18920 -4.2 -3.3 ATP phosphoribosyltransferase compare
BWI76_RS00835 -4.2 -12.2 phosphoenolpyruvate carboxylase compare
BWI76_RS27385 -4.1 -6.9 orotate phosphoribosyltransferase compare
BWI76_RS07065 -4.0 -7.6 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS09660 -3.9 -2.7 DNA translocase FtsK compare
BWI76_RS18940 -3.9 -4.0 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS24285 -3.9 -8.6 cystathionine beta-lyase compare
BWI76_RS04240 -3.9 -2.6 thr operon leader peptide compare
BWI76_RS01350 -3.8 -1.5 NAD(P)H-flavin reductase compare
BWI76_RS20435 -3.8 -2.1 chorismate synthase compare
BWI76_RS27390 -3.8 -4.1 ribonuclease PH compare
BWI76_RS00990 -3.7 -6.9 ketol-acid reductoisomerase compare
BWI76_RS22765 -3.7 -11.6 sulfite reductase subunit alpha compare
BWI76_RS03010 -3.7 -6.2 ornithine carbamoyltransferase compare
BWI76_RS21465 -3.6 -4.0 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS01210 -3.6 -3.3 tyrosine recombinase XerC compare
BWI76_RS22760 -3.6 -6.5 sulfite reductase subunit beta compare
BWI76_RS00400 -3.4 -2.1 glutamine synthetase compare
BWI76_RS01610 -3.2 -7.0 phosphoribosylamine--glycine ligase compare
BWI76_RS08395 -3.2 -2.8 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS11845 -3.2 -1.3 tryptophan synthase subunit beta compare
BWI76_RS02530 -3.2 -3.7 tRNA dimethylallyltransferase compare
BWI76_RS01185 -3.1 -2.2 adenylate cyclase compare
BWI76_RS23885 -3.1 -2.4 2-octaprenylphenol hydroxylase compare
BWI76_RS27185 -3.1 -9.0 L-lactate/D-lactate permease (from data) conserved
BWI76_RS23240 -2.9 -4.4 exonuclease V subunit gamma compare
BWI76_RS10990 -2.9 -1.8 dihydroorotase compare
BWI76_RS27190 -2.8 -4.4 transcriptional regulator LldR conserved
BWI76_RS19010 -2.7 -5.0 polysaccharide pyruvyl transferase yvff compare
BWI76_RS02735 -2.7 -5.7 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS23480 -2.6 -11.8 EAL domain-containing protein compare
BWI76_RS05015 -2.6 -2.5 transcriptional regulator compare
BWI76_RS09190 -2.5 -5.1 hypothetical protein compare
BWI76_RS20970 -2.4 -2.1 phosphoribosylglycinamide formyltransferase compare
BWI76_RS09645 -2.4 -1.9 thioredoxin-disulfide reductase compare
BWI76_RS20640 -2.4 -5.7 cysteine synthase A compare
BWI76_RS06185 -2.4 -6.9 shikimate kinase II compare
BWI76_RS08980 -2.3 -1.8 DNA starvation/stationary phase protection protein compare
BWI76_RS23230 -2.3 -4.0 exodeoxyribonuclease V subunit beta compare
BWI76_RS26570 -2.3 -3.6 anion permease compare
BWI76_RS00345 -2.2 -3.2 protein disulfide oxidoreductase DsbA compare
BWI76_RS08405 -2.1 -3.0 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS03595 -2.1 -1.7 ethanolamine utilization protein EutM compare
BWI76_RS15825 -2.0 -2.6 hypothetical protein compare
BWI76_RS25320 -1.9 -6.8 glutamate synthase compare
BWI76_RS19465 -1.9 -3.0 hypothetical protein compare
BWI76_RS26000 -1.8 -6.1 aspartate aminotransferase family protein compare
BWI76_RS25315 -1.8 -9.0 glutamate synthase large subunit compare
BWI76_RS18605 -1.8 -1.9 oxidoreductase molybdopterin-binding protein compare
BWI76_RS20440 -1.7 -1.3 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS08430 -1.7 -6.3 succinate--CoA ligase subunit alpha compare
BWI76_RS08535 -1.7 -2.4 translocation protein TolB compare
BWI76_RS05950 -1.6 -1.8 polar amino acid ABC transporter inner membrane subunit compare
BWI76_RS08425 -1.6 -4.7 succinyl-CoA ligase subunit beta compare
BWI76_RS15760 -1.6 -2.1 hypothetical protein compare
BWI76_RS27440 -1.5 -3.1 DNA helicase RecG compare
BWI76_RS00390 -1.5 -4.5 two-component system sensor histidine kinase NtrB compare
BWI76_RS19840 -1.5 -1.5 hypothetical protein compare
BWI76_RS24900 -1.5 -1.6 DeoR family transcriptional regulator compare
BWI76_RS25160 -1.5 -1.9 transcription elongation factor GreA compare
BWI76_RS21310 -1.5 -1.2 DNA repair protein RecO compare
BWI76_RS13435 -1.5 -2.1 hypothetical protein compare
BWI76_RS21140 -1.4 -2.9 molecular chaperone HscA compare
BWI76_RS07820 -1.4 -2.2 S-methyl-5-thioribose kinase compare
BWI76_RS00025 -1.4 -1.0 hypothetical protein compare
BWI76_RS27875 -1.4 -1.5 membrane protein compare
BWI76_RS15830 -1.4 -2.6 hypothetical protein compare
BWI76_RS26055 -1.3 -4.8 siroheme synthase compare
BWI76_RS05200 -1.3 -2.1 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS00960 -1.3 -4.5 acetolactate synthase 2 catalytic subunit compare
BWI76_RS15810 -1.3 -4.2 hypothetical protein compare
BWI76_RS25600 -1.3 -1.1 tRNA-Thr compare
BWI76_RS16275 -1.3 -2.3 fumarate hydratase FumA compare
BWI76_RS22420 -1.3 -2.4 LacI family transcriptional regulator compare
BWI76_RS27455 -1.3 -2.6 DUF805 domain-containing protein compare
BWI76_RS06465 -1.3 -1.4 IclR family transcriptional regulator compare
BWI76_RS21370 -1.3 -1.8 ATP-dependent RNA helicase SrmB compare
BWI76_RS07640 -1.2 -1.4 short chain dehydrogenase compare
BWI76_RS01540 -1.2 -1.5 thiamine biosynthesis protein ThiS compare
BWI76_RS03080 -1.2 -2.5 (Fe-S)-cluster assembly protein compare
BWI76_RS07160 -1.2 -2.4 MBL fold hydrolase compare
BWI76_RS21565 -1.2 -1.1 outer membrane protein assembly factor BamE compare
BWI76_RS23265 -1.1 -2.8 hypothetical protein compare
BWI76_RS21480 -1.1 -2.5 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS25425 -1.1 -1.5 arginine repressor compare
BWI76_RS03880 -1.1 -2.2 homoprotocatechuate degradation operon regulator, HpaR compare
BWI76_RS13600 -1.1 -2.7 hypothetical protein compare
BWI76_RS02985 -1.1 -2.7 reactive intermediate/imine deaminase compare
BWI76_RS25645 -1.1 -4.0 shikimate dehydrogenase compare
BWI76_RS12460 -1.1 -2.6 envelope stress response membrane protein PspC compare
BWI76_RS01115 -1.0 -2.7 dTDP-4-amino-4,6-dideoxygalactose transaminase compare
BWI76_RS21810 -1.0 -1.6 universal stress protein compare
BWI76_RS09640 -1.0 -3.4 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD compare
BWI76_RS15835 -1.0 -0.7 hypothetical protein compare
BWI76_RS05965 -1.0 -2.1 hypothetical protein compare
BWI76_RS15680 -1.0 -3.1 hypothetical protein compare
BWI76_RS01895 -1.0 -2.3 cupin compare
BWI76_RS26685 -1.0 -4.0 glutathione-disulfide reductase compare
BWI76_RS11300 -1.0 -1.2 cupin compare
BWI76_RS20995 -1.0 -3.1 RNA degradosome polyphosphate kinase compare
BWI76_RS08260 -1.0 -2.1 LysR family transcriptional regulator compare
BWI76_RS07465 -1.0 -2.2 TetR family transcriptional regulator compare
BWI76_RS19495 -1.0 -1.2 ABC transporter, quaternary amine uptake transporter (QAT) family, ATP-binding protein compare
BWI76_RS06485 -1.0 -2.0 cytochrome o ubiquinol oxidase subunit III compare
BWI76_RS20785 -1.0 -1.0 ethanolamine utilization protein EutJ compare
BWI76_RS27915 -1.0 -1.9 YceK/YidQ family lipoprotein compare
BWI76_RS21165 -1.0 -1.6 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS15955 -1.0 -6.2 transcriptional regulator compare
BWI76_RS18190 -1.0 -3.1 carboxy-S-adenosyl-L-methionine synthase CmoA compare
BWI76_RS06475 -1.0 -1.0 protoheme IX farnesyltransferase compare
BWI76_RS26620 -1.0 -1.0 Fe-S biogenesis protein NfuA compare
BWI76_RS26460 -1.0 -2.8 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS11900 -1.0 -1.0 cob(I)yrinic acid a,c-diamide adenosyltransferase compare
BWI76_RS24850 -0.9 -4.1 DeoR family transcriptional regulator compare
BWI76_RS04050 -0.9 -2.2 hydroxamate siderophore iron reductase FhuF compare
BWI76_RS08500 -0.9 -1.3 cytochrome d ubiquinol oxidase subunit 2 compare
BWI76_RS15135 -0.9 -1.9 hypothetical protein compare
BWI76_RS01800 -0.9 -1.8 glucose-6-phosphate isomerase compare
BWI76_RS00385 -0.9 -4.2 nitrogen assimilation regulatory protein compare
BWI76_RS11235 -0.9 -1.1 hypothetical protein compare
BWI76_RS19360 -0.9 -3.0 glucose dehydrogenase compare
BWI76_RS27430 -0.9 -0.9 (p)ppGpp synthetase compare
BWI76_RS02970 -0.9 -2.3 trehalose operon repressor compare
BWI76_RS26395 -0.9 -2.5 cell division protein FtsE compare
BWI76_RS27950 -0.9 -1.4 transcriptional regulator compare
BWI76_RS17675 -0.9 -1.0 hypothetical protein compare
BWI76_RS13755 -0.9 -1.4 hypothetical protein compare
BWI76_RS26065 -0.9 -2.0 phosphoglycolate phosphatase compare
BWI76_RS17720 -0.9 -1.2 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS22805 -0.9 -3.8 GTP diphosphokinase compare
BWI76_RS27820 -0.9 -1.2 ilvB operon leader peptide IvbL compare
BWI76_RS09110 -0.9 -2.5 glutathione ABC transporter permease GsiD compare
BWI76_RS21505 -0.9 -0.9 hypothetical protein compare
BWI76_RS03295 -0.9 -1.4 transposase compare
BWI76_RS22695 -0.9 -2.5 sulfate adenylyltransferase compare
BWI76_RS06810 -0.9 -2.3 hypothetical protein compare
BWI76_RS07380 -0.9 -2.0 hypothetical protein compare
BWI76_RS27170 -0.9 -3.7 MltR family transcriptional regulator compare
BWI76_RS21100 -0.8 -1.7 nucleoside-diphosphate kinase compare
BWI76_RS06735 -0.8 -1.5 50S ribosomal protein L31 compare
BWI76_RS17665 -0.8 -1.5 proteasome-type protease compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source Sodium L-Lactate in Klebsiella michiganensis M5al

For carbon source Sodium L-Lactate across organisms