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Experiment set5IT045 for
Methanococcus maripaludis S2
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H2 deepwell autotrophic conditions
200 most important genes:
gene
name
fitness
t score
description
MMP
_RS07845
-8.4
-2.4
LL-diaminopimelate aminotransferase
compare
MMP
_RS06975
-7.7
-2.2
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMP
_RS05500
-7.7
-7.3
2-isopropylmalate synthase
compare
MMP
_RS01455
-7.7
-6.0
nickel pincer cofactor biosynthesis protein LarC
compare
MMP
_RS08210
-6.8
-2.3
phosphatidylglycerophosphatase A
compare
MMP
_RS06400
-6.5
-1.8
4Fe-4S binding protein
compare
MMP
_RS01795
-6.4
-1.8
methanogenesis marker 6 protein
compare
MMP
_RS07185
-6.4
-13.3
pyridoxal phosphate-dependent aminotransferase
compare
MMP
_RS03450
-6.3
-2.4
glycine synthesis protein GlyXS
(from data)
compare
MMP
_RS03035
-6.2
-2.9
4-hydroxy-tetrahydrodipicolinate synthase
compare
MMP
_RS06885
-6.2
-2.3
50S ribosome-binding GTPase
compare
MMP
_RS00750
-6.2
-2.3
fumarate hydratase
compare
MMP
_RS04710
-6.1
-1.7
hypothetical protein
compare
MMP
_RS05930
-6.1
-2.2
3-isopropylmalate dehydratase large subunit
compare
MMP
_RS05085
-6.0
-9.4
AAA family ATPase
compare
MMP
_RS02135
-6.0
-5.0
DUF5612 domain-containing protein
compare
MMP
_RS01020
-6.0
-1.0
3 4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMP
_RS07630
-5.9
-1.7
ATP-binding cassette domain-containing protein
compare
MMP
_RS04620
-5.9
-13.8
cobalt transporter CbiM
compare
MMP
_RS05095
-5.9
-7.0
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMP
_RS07345
-5.8
-5.3
glycine synthesis protein GlyXL
(from data)
compare
MMP
_RS08095
-5.8
-7.6
dethiobiotin synthase
compare
MMP
_RS01175
-5.8
-4.1
triphosphoribosyl-dephospho-CoA synthase
compare
MMP
_RS03435
-5.7
-1.9
ketol-acid reductoisomerase
compare
MMP
_RS02280
-5.7
-0.9
DUF211 domain-containing protein
compare
MMP
_RS05090
-5.7
-8.3
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
MMP
_RS05070
-5.6
-8.9
4Fe-4S dicluster domain-containing protein
compare
MMP
_RS06370
-5.6
-4.7
biotin synthase BioB
compare
MMP
_RS05060
-5.5
-11.5
AAA family ATPase
compare
MMP
_RS03640
-5.5
-3.9
archaeal proteasome endopeptidase complex subunit beta
compare
MMP
_RS05100
-5.5
-17.5
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
compare
MMP
_RS08790
-5.5
-1.8
translation initiation factor IF-2 subunit alpha
compare
MMP
_RS07730
-5.4
-2.0
pyruvate synthase subunit beta
compare
MMP
_RS04775
-5.4
-3.6
adenosylhomocysteinase
compare
MMP
_RS06270
-5.4
-6.2
TIGR00300 family protein
compare
MMP
_RS08745
-5.3
-7.0
CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMP
_RS05065
-5.3
-4.3
CooT family nickel-binding protein
compare
MMP
_RS04500
-5.2
-15.6
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
MMP
_RS05080
-5.2
-10.0
acetyl-CoA decarbonylase/synthase complex subunit delta
compare
MMP
_RS04685
-5.2
-3.5
DUF126 domain-containing protein
compare
MMP
_RS06355
-5.1
-2.7
molybdenum cofactor biosynthesis protein MoaE
compare
MMP
_RS04215
-5.1
-6.6
nickel pincer cofactor biosynthesis protein LarB
compare
MMP
_RS03960
-5.1
-0.8
hypothetical protein
compare
MMP
_RS05075
-5.1
-16.5
acetyl-CoA decarbonylase/synthase complex subunit gamma
compare
MMP
_RS04605
-5.1
-3.7
cobalt ECF transporter T component CbiQ
compare
MMP
_RS05265
-5.0
-2.0
2-isopropylmalate synthase
compare
MMP
_RS03015
-5.0
-9.5
GTP 3' 8-cyclase MoaA
compare
MMP
_RS03315
-5.0
-1.4
ferrous iron transport protein A
compare
MMP
_RS08105
-4.9
-6.5
6-carboxyhexanoate--CoA ligase
compare
MMP
_RS03400
-4.9
-3.1
archease
compare
MMP
_RS08650
-4.8
-3.3
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMP
_RS06230
-4.8
-2.1
helix-turn-helix domain-containing protein
compare
MMP
_RS01005
-4.8
-1.1
riboflavin synthase
compare
MMP
_RS06625
-4.8
-2.1
DNA primase
compare
MMP
_RS09020
-4.8
-1.8
hypothetical protein
compare
MMP
_RS04780
-4.7
-3.7
ribonuclease P
compare
MMP
_RS08300
-4.7
-1.3
metal-sulfur cluster assembly factor
compare
MMP
_RS05515
-4.7
-7.7
cyclic pyranopterin monophosphate synthase MoaC
compare
MMP
_RS07390
-4.7
-2.6
cell division protein FtsZ
compare
MMP
_RS07380
-4.6
-2.3
transcription elongation factor Spt5
compare
MMP
_RS01755
-4.6
-1.1
DUF2097 domain-containing protein
compare
MMP
_RS03700
-4.6
-10.7
sodium:proton antiporter
compare
MMP
_RS06375
-4.6
-4.1
ATP-dependent sacrificial sulfur transferase LarE
compare
MMP
_RS03445
-4.5
-1.1
methanogenesis marker 17 protein
compare
MMP
_RS05055
-4.5
-12.3
DUF166 domain-containing protein
compare
MMP
_RS04615
-4.5
-4.1
PDGLE domain-containing protein
compare
MMP
_RS05425
-4.5
-5.2
monovalent cation/H+ antiporter complex subunit F
compare
MMP
_RS03600
-4.5
-2.3
triose-phosphate isomerase
compare
MMP
_RS08100
-4.5
-6.4
8-amino-7-oxononanoate synthase
compare
MMP
_RS00300
-4.4
-0.7
6 7-dimethyl-8-ribityllumazine synthase
compare
MMP
_RS05250
-4.4
-1.4
NFYB/HAP3 family transcription factor subunit
compare
MMP
_RS08715
-4.4
-1.9
formylmethanofuran dehydrogenase subunit B
compare
MMP
_RS07545
-4.4
-1.0
HTH domain-containing protein
compare
MMP
_RS08440
-4.3
-3.0
cell division protein SepF
compare
MMP
_RS08635
-4.3
-1.7
UbiA family prenyltransferase
compare
MMP
_RS07645
-4.2
-5.7
aldehyde dehydrogenase family protein
compare
MMP
_RS01325
-4.2
-2.2
dihydroneopterin aldolase family protein
compare
MMP
_RS02145
-4.2
-9.3
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS01800
-4.2
-4.3
TIGR00303 family protein
compare
MMP
_RS06475
-4.2
-5.1
FAD-dependent oxidoreductase
compare
MMP
_RS08460
-4.1
-2.7
proteasome-activating nucleotidase
compare
MMP
_RS03580
-4.1
-3.9
signal recognition particle-docking protein FtsY
compare
MMP
_RS00515
-4.1
-0.9
DUF655 domain-containing protein
compare
MMP
_RS02900
-4.0
-0.7
imidazoleglycerol-phosphate dehydratase HisB
compare
MMP
_RS07600
-4.0
-2.6
Ni-sirohydrochlorin a c-diamide synthase
compare
MMP
_RS02240
-3.8
-3.7
methanogenesis marker 7 protein
compare
MMP
_RS01500
-3.8
-2.2
CBS domain-containing protein
compare
MMP
_RS07200
-3.7
-6.0
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMP
_RS06630
-3.7
-0.9
UPF0058 family protein
compare
MMP
_RS06340
-3.7
-9.0
phosphoadenosine phosphosulfate reductase family protein
compare
MMP
_RS01910
-3.7
-10.6
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMP
_RS06925
-3.7
-2.3
ribonuclease VapC4
compare
MMP
_RS00110
-3.6
-3.0
hypothetical protein
compare
MMP
_RS05925
-3.6
-3.8
small nuclear ribonucleoprotein
compare
MMP
_RS06020
-3.6
-5.1
archaeoflavoprotein AfpA
compare
MMP
_RS07735
-3.6
-0.8
2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
compare
MMP
_RS06350
-3.6
-6.7
HesA/MoeB/ThiF family protein
compare
MMP
_RS07195
-3.6
-9.9
M20 family metallo-hydrolase
compare
MMP
_RS02010
-3.6
-9.9
PHP domain-containing protein
compare
MMP
_RS01905
-3.6
-15.1
glycosyltransferase
compare
MMP
_RS05550
-3.5
-0.8
cation:proton antiporter
compare
MMP
_RS07635
-3.5
-7.9
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMP
_RS01220
-3.5
-7.9
hypothetical protein
compare
MMP
_RS01900
-3.5
-13.5
hypothetical protein
compare
MMP
_RS01610
-3.5
-3.0
hypothetical protein
compare
MMP
_RS03205
-3.5
-1.1
peptidyl-tRNA hydrolase Pth2
compare
MMP
_RS06670
-3.4
-6.4
glucose-6-phosphate isomerase
compare
MMP
_RS07580
-3.4
-2.9
DUF356 domain-containing protein
compare
MMP
_RS05920
-3.3
-0.8
50S ribosomal protein L37e
compare
MMP
_RS07555
-3.3
-0.8
monovalent cation/H+ antiporter subunit E
compare
MMP
_RS04890
-3.3
-0.8
adenylyltransferase/cytidyltransferase family protein
compare
MMP
_RS03140
-3.3
-12.3
hypothetical protein
compare
MMP
_RS04790
-3.2
-11.1
4-hydroxy-tetrahydrodipicolinate reductase
compare
MMP
_RS07955
-3.2
-5.5
FumA C-terminus/TtdB family hydratase beta subunit
compare
MMP
_RS00130
-3.2
-1.0
nickel-responsive transcriptional regulator NikR
compare
MMP
_RS01915
-3.2
-14.2
DUF354 domain-containing protein
compare
MMP
_RS05555
-3.2
-1.6
DUF4040 domain-containing protein
compare
MMP
_RS05845
-3.2
-1.8
tRNA-intron lyase
compare
MMP
_RS06295
-3.1
-5.9
methanogenesis marker 14 protein
compare
MMP
_RS00685
-3.1
-4.2
2-phospho-L-lactate guanylyltransferase
compare
MMP
_RS02345
-3.0
-3.4
GTP-dependent dephospho-CoA kinase family protein
compare
MMP
_RS06930
-3.0
-10.7
MBL fold metallo-hydrolase
compare
MMP
_RS00305
-3.0
-1.8
phosphoribosyl-ATP diphosphatase
compare
MMP
_RS08240
-3.0
-6.3
methanogenesis marker 16 metalloprotein
compare
MMP
_RS01385
-3.0
-0.7
imidazole glycerol phosphate synthase subunit HisH
compare
MMP
_RS06895
-3.0
-1.7
selenocysteine-specific translation elongation factor
compare
MMP
_RS06315
-3.0
-1.0
cobalt-precorrin-7 (C(5))-methyltransferase
compare
MMP
_RS01925
-2.9
-8.1
DUF1616 domain-containing protein
compare
MMP
_RS03420
-2.9
-4.4
acetolactate synthase small subunit
compare
MMP
_RS01960
-2.9
-0.7
hypothetical protein
compare
MMP
_RS01265
-2.9
-1.8
hypothetical protein
compare
MMP
_RS03145
-2.9
-6.0
fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
compare
MMP
_RS06285
-2.9
-2.1
precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
compare
MMP
_RS07525
-2.9
-7.7
4Fe-4S binding protein
compare
MMP
_RS02195
-2.9
-3.6
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
compare
MMP
_RS08820
-2.8
-5.7
hypothetical protein
compare
MMP
_RS07435
-2.8
-2.1
GMP synthase subunit A
compare
MMP
_RS01225
-2.8
-4.8
DUF5379 domain-containing protein
compare
MMP
_RS08330
-2.8
-4.2
NADH-quinone oxidoreductase subunit H
compare
MMP
_RS02355
-2.8
-2.8
30S ribosomal protein S27ae
compare
MMP
_RS08645
-2.7
-6.8
UPF0179 family protein
compare
MMP
_RS07755
-2.7
-1.0
DUF555 domain-containing protein
compare
MMP
_RS02875
-2.6
-8.5
chorismate pyruvate-lyase family protein
compare
MMP
_RS01970
-2.6
-11.0
TIGR04279 domain-containing protein
compare
MMP
_RS06730
-2.5
-1.9
phosphopantothenate/pantothenate synthetase
compare
MMP
_RS01545
-2.5
-0.8
CBS domain-containing protein
compare
MMP
_RS01895
-2.5
-10.3
flippase
compare
MMP
_RS00895
-2.5
-3.3
hypothetical protein
compare
MMP
_RS03025
-2.5
-3.8
molybdenum cofactor guanylyltransferase
compare
MMP
_RS07365
-2.5
-9.2
2-phosphoglycerate kinase
compare
MMP
_RS00985
-2.5
-4.5
CDC48 family AAA ATPase
compare
MMP
_RS05640
-2.5
-5.8
UTP--glucose-1-phosphate uridylyltransferase GalU
compare
MMP
_RS06310
-2.4
-3.6
NAD(P)/FAD-dependent oxidoreductase
compare
MMP
_RS08335
-2.4
-6.4
NADH-quinone oxidoreductase subunit B family protein
compare
MMP
_RS08720
-2.4
-1.4
4Fe-4S binding protein
compare
MMP
_RS01725
-2.3
-4.1
class I SAM-dependent methyltransferase family protein
compare
MMP
_RS02800
-2.3
-4.8
nucleotidyltransferase domain-containing protein
compare
MMP
_RS06105
-2.3
-7.0
hydrogenase maturation peptidase HycI
compare
MMP
_RS07625
-2.3
-3.2
cobalt ECF transporter T component CbiQ
compare
MMP
_RS03095
-2.3
-5.8
diphthine synthase
compare
MMP
_RS07605
-2.3
-1.8
diadenylate cyclase
compare
MMP
_RS00900
-2.3
-1.9
50S ribosomal protein L39e
compare
MMP
_RS03390
-2.2
-5.9
malate dehydrogenase
compare
MMP
_RS02885
-2.2
-13.4
molybdopterin biosynthesis protein
compare
MMP
_RS01830
-2.2
-1.5
tRNA-Val
compare
MMP
_RS01975
-2.2
-11.7
hypothetical protein
compare
MMP
_RS07720
-2.1
-10.9
4Fe-4S binding protein
compare
MMP
_RS08165
-2.1
-2.4
phosphoglycerate dehydrogenase
compare
MMP
_RS07620
-2.1
-4.1
energy-coupling factor ABC transporter substrate-binding protein
compare
MMP
_RS08360
-2.1
-5.3
hypothetical protein
compare
MMP
_RS01920
-2.1
-11.2
glycosyltransferase family 2 protein
compare
MMP
_RS07615
-2.1
-5.6
energy-coupling factor ABC transporter permease
compare
MMP
_RS07575
-2.1
-3.8
RNA ligase partner protein
compare
MMP
_RS06120
-2.1
-1.5
UPF0147 family protein
compare
MMP
_RS04875
-2.1
-4.5
energy-converting hydrogenase B subunit P
compare
MMP
_RS01700
-2.1
-0.9
dihydroxy-acid dehydratase
compare
MMP
_RS06980
-2.0
-5.8
tRNA 2-thiocytidine biosynthesis TtcA family protein
compare
MMP
_RS08760
-2.0
-1.3
hypothetical protein
compare
MMP
_RS00695
-2.0
-0.7
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMP
_RS05280
-2.0
-7.2
COG1361 S-layer family protein
compare
MMP
_RS08340
-2.0
-4.1
4Fe-4S binding protein
compare
MMP
_RS08365
-1.9
-4.2
energy conserving hydrogenase EhbF
compare
MMP
_RS07710
-1.9
-5.0
cell division protein FtsZ
compare
MMP
_RS08345
-1.9
-10.3
4Fe-4S binding protein
compare
MMP
_RS03155
-1.9
-5.8
precorrin-6A reductase
compare
MMP
_RS01885
-1.9
-5.6
Gfo/Idh/MocA family oxidoreductase
compare
MMP
_RS01380
-1.9
-2.1
PHP domain-containing protein
compare
MMP
_RS08445
-1.8
-3.5
DUF2099 family protein
compare
MMP
_RS01880
-1.8
-3.4
DegT/DnrJ/EryC1/StrS family aminotransferase
compare
MMP
_RS00810
-1.8
-5.3
topoisomerase DNA-binding C4 zinc finger domain-containing protein
compare
MMP
_RS06700
-1.8
-7.6
hypothetical protein
compare
MMP
_RS04585
-1.8
-6.8
AIR synthase related protein
compare
MMP
_RS01875
-1.8
-6.8
N-acetyltransferase
compare
MMP
_RS01665
-1.8
-3.5
DUF2111 domain-containing protein
compare
MMP
_RS05950
-1.8
-7.4
nickel-dependent hydrogenase large subunit
compare
MMP
_RS00315
-1.7
-4.8
Nif3-like dinuclear metal center hexameric protein
compare
MMP
_RS07750
-1.7
-3.7
DUF357 domain-containing protein
compare
MMP
_RS07005
-1.7
-0.5
4Fe-4S binding protein
compare
MMP
_RS08435
-1.7
-1.6
Era-like GTP-binding protein
compare
MMP
_RS08320
-1.7
-4.7
molybdopterin molybdotransferase MoeA
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis S2 in nutrient t2 experiments