Experiment set5IT045 for Klebsiella michiganensis M5al

Compare to:

Sodium D-Lactate carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS18920 -6.7 -4.6 ATP phosphoribosyltransferase compare
BWI76_RS00805 -6.3 -6.2 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS00990 -6.3 -8.6 ketol-acid reductoisomerase compare
BWI76_RS18940 -6.1 -7.2 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS18950 -5.8 -6.4 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS05840 -5.7 -6.7 glutamate 5-kinase compare
BWI76_RS18935 -5.6 -6.1 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS23220 -5.6 -7.6 amino-acid N-acetyltransferase compare
BWI76_RS26085 -5.5 -3.7 3-dehydroquinate synthase compare
BWI76_RS04465 -5.3 -6.3 carbamoyl-phosphate synthase small subunit compare
BWI76_RS04255 -5.3 -10.1 threonine synthase compare
BWI76_RS21465 -5.3 -5.7 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS04670 -5.2 -11.0 3-isopropylmalate dehydratase large subunit compare
BWI76_RS03010 -5.2 -9.9 ornithine carbamoyltransferase compare
BWI76_RS09755 -5.1 -7.7 phosphoserine transaminase compare
BWI76_RS04250 -5.1 -7.4 homoserine kinase compare
BWI76_RS00845 -5.0 -9.2 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS20155 -5.0 -3.4 NADH-quinone oxidoreductase subunit I compare
BWI76_RS09645 -5.0 -2.2 thioredoxin-disulfide reductase compare
BWI76_RS21475 -5.0 -7.5 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS00835 -5.0 -15.2 phosphoenolpyruvate carboxylase compare
BWI76_RS02815 -4.9 -4.6 fructose-bisphosphatase class I compare
BWI76_RS00855 -4.8 -9.1 argininosuccinate lyase compare
BWI76_RS04470 -4.7 -11.1 carbamoyl phosphate synthase large subunit compare
BWI76_RS04685 -4.7 -12.8 putative leucine operon leader peptide compare
BWI76_RS01615 -4.7 -11.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS01655 -4.6 -7.1 homoserine O-succinyltransferase compare
BWI76_RS00850 -4.5 -10.3 acetylglutamate kinase compare
BWI76_RS02995 -4.5 -9.6 aspartate carbamoyltransferase compare
BWI76_RS04665 -4.5 -18.9 3-isopropylmalate dehydratase small subunit compare
BWI76_RS00985 -4.4 -7.3 transcriptional regulator IlvY compare
BWI76_RS04675 -4.4 -7.1 3-isopropylmalate dehydrogenase compare
BWI76_RS21265 -4.4 -16.1 phosphoribosylformylglycinamidine synthase compare
BWI76_RS08385 -4.3 -5.8 citrate (Si)-synthase compare
BWI76_RS04160 -4.3 -6.8 phosphoserine phosphatase compare
BWI76_RS08405 -4.2 -5.0 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS20965 -4.2 -5.5 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS04680 -4.1 -9.5 2-isopropylmalate synthase compare
BWI76_RS24900 -4.1 -2.8 DeoR family transcriptional regulator compare
BWI76_RS05835 -4.1 -4.8 gamma-glutamyl-phosphate reductase compare
BWI76_RS23920 -4.1 -4.6 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS18930 -4.1 -6.6 histidinol-phosphate transaminase compare
BWI76_RS04245 -4.0 -14.6 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS11860 -4.0 -7.5 anthranilate synthase component I compare
BWI76_RS04645 -4.0 -6.5 3-dehydroquinase compare
BWI76_RS18925 -4.0 -6.6 histidinol dehydrogenase compare
BWI76_RS11850 -3.9 -9.2 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS11840 -3.9 -6.5 tryptophan synthase subunit alpha compare
BWI76_RS24285 -3.9 -9.3 cystathionine beta-lyase compare
BWI76_RS27385 -3.8 -8.0 orotate phosphoribosyltransferase compare
BWI76_RS20435 -3.8 -2.3 chorismate synthase compare
BWI76_RS09910 -3.8 -16.3 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS04705 -3.7 -8.3 DNA-binding transcriptional regulator FruR compare
BWI76_RS25115 -3.7 -5.7 argininosuccinate synthase compare
BWI76_RS22765 -3.7 -12.3 sulfite reductase subunit alpha compare
BWI76_RS23240 -3.6 -4.2 exonuclease V subunit gamma compare
BWI76_RS00975 -3.6 -7.1 dihydroxy-acid dehydratase compare
BWI76_RS00980 -3.5 -12.5 PLP-dependent threonine dehydratase compare
BWI76_RS07065 -3.5 -8.5 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS23365 -3.5 -8.9 LysR family transcriptional regulator compare
BWI76_RS01610 -3.5 -6.6 phosphoribosylamine--glycine ligase compare
BWI76_RS00400 -3.4 -2.3 glutamine synthetase compare
BWI76_RS20895 -3.4 -7.2 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS11965 -3.4 -6.7 orotidine-5'-phosphate decarboxylase compare
BWI76_RS11855 -3.3 -8.8 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS07070 -3.3 -7.0 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS09760 -3.3 -5.3 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS03080 -3.3 -4.4 (Fe-S)-cluster assembly protein compare
BWI76_RS18955 -3.2 -3.6 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS01185 -3.2 -2.2 adenylate cyclase compare
BWI76_RS05200 -3.1 -3.7 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS27185 -3.1 -12.3 L-lactate/D-lactate permease (from data) conserved
BWI76_RS23360 -3.1 -5.1 diaminopimelate decarboxylase compare
BWI76_RS22755 -3.0 -5.3 phosphoadenosine phosphosulfate reductase compare
BWI76_RS20350 -3.0 -4.8 amidophosphoribosyltransferase compare
BWI76_RS19515 -3.0 -5.6 D-lactate dehydrogenase (cytochrome c-553) (EC 1.1.2.5) (from data) conserved
BWI76_RS25420 -2.9 -7.8 malate dehydrogenase compare
BWI76_RS11845 -2.9 -2.3 tryptophan synthase subunit beta compare
BWI76_RS23230 -2.9 -3.3 exodeoxyribonuclease V subunit beta compare
BWI76_RS22760 -2.9 -11.9 sulfite reductase subunit beta compare
BWI76_RS20355 -2.8 -4.8 colicin V production protein compare
BWI76_RS05015 -2.8 -2.7 transcriptional regulator compare
BWI76_RS09660 -2.8 -3.0 DNA translocase FtsK compare
BWI76_RS22690 -2.7 -5.1 adenylyl-sulfate kinase compare
BWI76_RS27815 -2.7 -12.0 acetolactate synthase catalytic subunit compare
BWI76_RS00785 -2.7 -5.8 cystathionine gamma-synthase compare
BWI76_RS06185 -2.7 -10.9 shikimate kinase II compare
BWI76_RS08395 -2.6 -3.0 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS20150 -2.6 -2.8 NADH:ubiquinone oxidoreductase subunit J compare
BWI76_RS17065 -2.6 -11.3 phosphoenolpyruvate synthase compare
BWI76_RS20140 -2.5 -7.2 NADH-quinone oxidoreductase subunit L compare
BWI76_RS20145 -2.5 -2.4 NADH-quinone oxidoreductase subunit K compare
BWI76_RS26620 -2.5 -1.9 Fe-S biogenesis protein NfuA compare
BWI76_RS15825 -2.5 -2.6 hypothetical protein compare
BWI76_RS27430 -2.5 -2.1 (p)ppGpp synthetase compare
BWI76_RS26055 -2.4 -9.3 siroheme synthase compare
BWI76_RS20270 -2.4 -6.6 hypothetical protein compare
BWI76_RS02735 -2.4 -6.0 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS08425 -2.4 -4.6 succinyl-CoA ligase subunit beta compare
BWI76_RS01210 -2.4 -3.2 tyrosine recombinase XerC compare
BWI76_RS04240 -2.4 -4.0 thr operon leader peptide compare
BWI76_RS25960 -2.3 -4.7 NUDIX hydrolase compare
BWI76_RS20170 -2.3 -3.8 NADH-quinone oxidoreductase subunit F compare
BWI76_RS21310 -2.3 -1.7 DNA repair protein RecO compare
BWI76_RS26570 -2.3 -3.8 anion permease compare
BWI76_RS27475 -2.2 -9.5 regulatory protein GntR family protein compare
BWI76_RS16275 -2.2 -3.4 fumarate hydratase FumA compare
BWI76_RS10990 -2.2 -2.1 dihydroorotase compare
BWI76_RS19600 -2.1 -7.4 hypothetical protein conserved
BWI76_RS03415 -2.1 -7.3 LacI family transcriptional regulator compare
BWI76_RS20190 -2.1 -7.4 NADH-quinone oxidoreductase subunit A compare
BWI76_RS08390 -2.1 -3.4 hypothetical protein compare
BWI76_RS19605 -2.1 -5.0 CidB/LrgB family autolysis modulator conserved
BWI76_RS22240 -2.1 -6.6 transcriptional regulator compare
BWI76_RS01680 -2.1 -8.9 transcriptional regulator IclR compare
BWI76_RS02095 -2.0 -8.3 acetyl-coenzyme A synthetase compare
BWI76_RS00965 -2.0 -1.7 acetolactate synthase 2 small subunit compare
BWI76_RS26455 -2.0 -4.4 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS12090 -2.0 -1.7 HNH endonuclease compare
BWI76_RS20640 -2.0 -6.2 cysteine synthase A compare
BWI76_RS08430 -2.0 -7.0 succinate--CoA ligase subunit alpha compare
BWI76_RS20135 -2.0 -4.1 NADH-quinone oxidoreductase subunit M compare
BWI76_RS02530 -2.0 -3.0 tRNA dimethylallyltransferase compare
BWI76_RS20165 -2.0 -6.2 NADH-quinone oxidoreductase subunit G compare
BWI76_RS27170 -2.0 -5.7 MltR family transcriptional regulator compare
BWI76_RS20180 -2.0 -6.0 NADH-quinone oxidoreductase subunit C/D compare
BWI76_RS07120 -1.9 -8.4 LacI family transcriptional regulator compare
BWI76_RS20130 -1.9 -4.8 NADH-quinone oxidoreductase subunit N compare
BWI76_RS20160 -1.8 -3.4 NADH-quinone oxidoreductase subunit H compare
BWI76_RS27190 -1.8 -6.7 transcriptional regulator LldR conserved
BWI76_RS06485 -1.8 -3.5 cytochrome o ubiquinol oxidase subunit III compare
BWI76_RS05120 -1.7 -5.8 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS06495 -1.7 -7.0 cytochrome ubiquinol oxidase subunit II compare
BWI76_RS25905 -1.7 -3.0 hypothetical protein compare
BWI76_RS27390 -1.7 -2.1 ribonuclease PH compare
BWI76_RS21480 -1.6 -5.2 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS03225 -1.6 -7.5 transcriptional regulator compare
BWI76_RS05450 -1.6 -2.1 ribonuclease HI compare
BWI76_RS27075 -1.5 -6.4 IclR family transcriptional regulator compare
BWI76_RS26175 -1.5 -2.6 DeoR/GlpR family transcriptional regulator compare
BWI76_RS20650 -1.5 -2.6 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS06765 -1.5 -4.1 transcriptional regulator compare
BWI76_RS09025 -1.5 -2.4 GntR family transcriptional regulator compare
BWI76_RS21985 -1.5 -8.4 acetaldehyde dehydrogenase (EC 1.2.1.3) (from data) compare
BWI76_RS06525 -1.5 -5.5 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS15835 -1.4 -1.0 hypothetical protein compare
BWI76_RS09530 -1.4 -1.4 hypothetical protein compare
BWI76_RS18110 -1.4 -3.8 transcriptional regulator HexR compare
BWI76_RS20380 -1.4 -1.4 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS23830 -1.4 -5.2 hypothetical protein compare
BWI76_RS11980 -1.4 -1.6 DeoR family transcriptional regulator compare
BWI76_RS21990 -1.4 -6.0 ATPase AAA compare
BWI76_RS08980 -1.4 -1.5 DNA starvation/stationary phase protection protein compare
BWI76_RS09190 -1.4 -3.9 hypothetical protein compare
BWI76_RS16235 -1.4 -4.4 membrane protein compare
BWI76_RS20440 -1.3 -3.2 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS00345 -1.3 -3.2 protein disulfide oxidoreductase DsbA compare
BWI76_RS07675 -1.3 -3.3 DeoR family transcriptional regulator compare
BWI76_RS20970 -1.3 -1.7 phosphoribosylglycinamide formyltransferase compare
BWI76_RS20910 -1.3 -4.8 glycine cleavage system transcriptional repressor compare
BWI76_RS22085 -1.3 -2.5 L-valine transporter subunit YgaH compare
BWI76_RS24850 -1.3 -6.5 DeoR family transcriptional regulator compare
BWI76_RS20915 -1.3 -4.2 peroxiredoxin compare
BWI76_RS17720 -1.3 -1.7 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS01885 -1.3 -1.5 CsbD family protein compare
BWI76_RS27820 -1.3 -1.6 ilvB operon leader peptide IvbL compare
BWI76_RS23915 -1.3 -2.3 5-formyltetrahydrofolate cyclo-ligase compare
BWI76_RS01385 -1.3 -2.5 potassium transporter compare
BWI76_RS00180 -1.2 -1.8 F0F1 ATP synthase subunit epsilon compare
BWI76_RS20995 -1.2 -2.3 RNA degradosome polyphosphate kinase compare
BWI76_RS02610 -1.2 -4.9 transcriptional regulator compare
BWI76_RS23520 -1.2 -1.7 hypothetical protein compare
BWI76_RS15955 -1.2 -6.8 transcriptional regulator compare
BWI76_RS15840 -1.2 -2.3 prophage protein compare
BWI76_RS09970 -1.2 -1.9 porin OmpA compare
BWI76_RS10700 -1.2 -2.5 XRE family transcriptional regulator compare
BWI76_RS00960 -1.1 -4.3 acetolactate synthase 2 catalytic subunit compare
BWI76_RS27810 -1.1 -6.8 acetolactate synthase isozyme 1 small subunit compare
BWI76_RS21100 -1.1 -1.2 nucleoside-diphosphate kinase compare
BWI76_RS25335 -1.1 -1.8 stringent starvation protein A compare
BWI76_RS18135 -1.1 -3.1 zinc ABC transporter ATP-binding protein ZnuC compare
BWI76_RS00240 -1.1 -2.0 FMN-binding protein MioC compare
BWI76_RS08520 -1.1 -2.9 colicin transporter TolQ compare
BWI76_RS06490 -1.1 -3.0 cytochrome ubiquinol oxidase subunit I compare
BWI76_RS22695 -1.1 -3.7 sulfate adenylyltransferase compare
BWI76_RS27165 -1.1 -3.0 mannitol-1-phosphate 5-dehydrogenase compare
BWI76_RS25070 -1.1 -1.3 hypothetical protein compare
BWI76_RS26460 -1.1 -3.5 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS26890 -1.1 -1.4 hypothetical protein compare
BWI76_RS16315 -1.1 -2.0 SirA-like protein compare
BWI76_RS22120 -1.1 -5.8 glutamate--cysteine ligase compare
BWI76_RS26075 -1.1 -2.0 DNA adenine methylase compare
BWI76_RS23480 -1.1 -5.5 EAL domain-containing protein compare
BWI76_RS15830 -1.1 -1.7 hypothetical protein compare
BWI76_RS27450 -1.1 -3.9 ferredoxin--NADP(+) reductase compare
BWI76_RS25505 -1.1 -5.9 RNase E specificity factor CsrD compare
BWI76_RS19495 -1.1 -1.4 ABC transporter, quaternary amine uptake transporter (QAT) family, ATP-binding protein compare
BWI76_RS06730 -1.1 -2.2 lac repressor compare
BWI76_RS08730 -1.0 -2.3 histidine utilization repressor compare
BWI76_RS23355 -1.0 -3.2 LacI family transcriptional regulator compare


Specific Phenotypes

For 12 genes in this experiment

For carbon source Sodium D-Lactate in Klebsiella michiganensis M5al

For carbon source Sodium D-Lactate across organisms