Experiment set5IT044 for Klebsiella michiganensis M5al

Compare to:

Trisodium citrate dihydrate carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS20355 -8.3 -5.7 colicin V production protein compare
BWI76_RS18930 -7.7 -6.6 histidinol-phosphate transaminase compare
BWI76_RS08430 -7.6 -5.3 succinate--CoA ligase subunit alpha compare
BWI76_RS05840 -7.0 -4.9 glutamate 5-kinase compare
BWI76_RS18925 -7.0 -6.8 histidinol dehydrogenase compare
BWI76_RS04160 -6.8 -8.1 phosphoserine phosphatase compare
BWI76_RS04465 -6.7 -4.6 carbamoyl-phosphate synthase small subunit compare
BWI76_RS04645 -6.6 -6.4 3-dehydroquinase compare
BWI76_RS18955 -6.5 -6.4 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS02815 -6.4 -4.4 fructose-bisphosphatase class I compare
BWI76_RS04470 -6.3 -9.7 carbamoyl phosphate synthase large subunit compare
BWI76_RS18940 -6.3 -7.5 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS21475 -6.0 -8.0 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS04685 -6.0 -10.7 putative leucine operon leader peptide compare
BWI76_RS23360 -5.9 -4.1 diaminopimelate decarboxylase compare
BWI76_RS00990 -5.9 -9.0 ketol-acid reductoisomerase compare
BWI76_RS01655 -5.8 -9.0 homoserine O-succinyltransferase compare
BWI76_RS04250 -5.8 -8.9 homoserine kinase compare
BWI76_RS04670 -5.7 -10.3 3-isopropylmalate dehydratase large subunit compare
BWI76_RS10990 -5.7 -3.4 dihydroorotase compare
BWI76_RS09755 -5.6 -8.4 phosphoserine transaminase compare
BWI76_RS26085 -5.6 -3.8 3-dehydroquinate synthase compare
BWI76_RS27385 -5.5 -5.4 orotate phosphoribosyltransferase compare
BWI76_RS04255 -5.5 -9.3 threonine synthase compare
BWI76_RS18920 -5.5 -4.8 ATP phosphoribosyltransferase compare
BWI76_RS01615 -5.5 -10.6 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS00855 -5.5 -9.2 argininosuccinate lyase compare
BWI76_RS00980 -5.3 -11.8 PLP-dependent threonine dehydratase compare
BWI76_RS04680 -5.1 -12.7 2-isopropylmalate synthase compare
BWI76_RS11855 -5.1 -9.7 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS00805 -5.1 -6.5 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS21265 -5.1 -11.4 phosphoribosylformylglycinamidine synthase compare
BWI76_RS11860 -5.0 -9.4 anthranilate synthase component I compare
BWI76_RS08405 -4.9 -4.8 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS08395 -4.9 -2.8 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS04675 -4.9 -7.3 3-isopropylmalate dehydrogenase compare
BWI76_RS20895 -4.9 -7.4 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS04245 -4.9 -16.7 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS02995 -4.8 -7.6 aspartate carbamoyltransferase compare
BWI76_RS00965 -4.7 -1.9 acetolactate synthase 2 small subunit compare
BWI76_RS11850 -4.7 -10.1 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS18950 -4.7 -3.7 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS21465 -4.7 -5.3 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS20350 -4.7 -7.4 amidophosphoribosyltransferase compare
BWI76_RS04665 -4.7 -13.4 3-isopropylmalate dehydratase small subunit compare
BWI76_RS09760 -4.6 -4.7 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS18935 -4.6 -6.5 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS07065 -4.5 -5.4 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS08425 -4.5 -5.1 succinyl-CoA ligase subunit beta compare
BWI76_RS20965 -4.4 -4.2 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS24285 -4.4 -7.1 cystathionine beta-lyase compare
BWI76_RS11965 -4.4 -3.9 orotidine-5'-phosphate decarboxylase compare
BWI76_RS23365 -4.4 -7.8 LysR family transcriptional regulator compare
BWI76_RS23830 -4.4 -9.1 hypothetical protein compare
BWI76_RS07070 -4.4 -6.6 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS22690 -4.4 -4.7 adenylyl-sulfate kinase compare
BWI76_RS09910 -4.3 -17.9 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS23920 -4.2 -7.9 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS22765 -4.1 -15.5 sulfite reductase subunit alpha compare
BWI76_RS00985 -4.1 -8.2 transcriptional regulator IlvY compare
BWI76_RS03010 -4.1 -6.8 ornithine carbamoyltransferase compare
BWI76_RS22755 -4.0 -7.1 phosphoadenosine phosphosulfate reductase compare
BWI76_RS05835 -4.0 -4.2 gamma-glutamyl-phosphate reductase compare
BWI76_RS00850 -3.9 -10.6 acetylglutamate kinase compare
BWI76_RS04240 -3.9 -2.6 thr operon leader peptide compare
BWI76_RS22760 -3.9 -8.4 sulfite reductase subunit beta compare
BWI76_RS20435 -3.9 -2.2 chorismate synthase compare
BWI76_RS25115 -3.9 -6.4 argininosuccinate synthase compare
BWI76_RS00785 -3.8 -7.0 cystathionine gamma-synthase compare
BWI76_RS08390 -3.8 -5.6 hypothetical protein compare
BWI76_RS00975 -3.8 -6.5 dihydroxy-acid dehydratase compare
BWI76_RS11845 -3.7 -3.6 tryptophan synthase subunit beta compare
BWI76_RS00845 -3.6 -7.9 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS01610 -3.6 -5.5 phosphoribosylamine--glycine ligase compare
BWI76_RS21140 -3.6 -4.8 molecular chaperone HscA compare
BWI76_RS00400 -3.5 -2.2 glutamine synthetase compare
BWI76_RS17720 -3.4 -2.4 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS27390 -3.4 -3.4 ribonuclease PH compare
BWI76_RS23220 -3.4 -7.5 amino-acid N-acetyltransferase compare
BWI76_RS23230 -3.4 -2.3 exodeoxyribonuclease V subunit beta compare
BWI76_RS20640 -3.4 -7.5 cysteine synthase A compare
BWI76_RS02735 -3.1 -6.2 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS01210 -3.1 -2.2 tyrosine recombinase XerC compare
BWI76_RS09645 -3.0 -2.1 thioredoxin-disulfide reductase compare
BWI76_RS11840 -3.0 -3.1 tryptophan synthase subunit alpha compare
BWI76_RS09660 -2.9 -3.1 DNA translocase FtsK compare
BWI76_RS25355 -2.7 -9.6 cell division protein ZapE compare
BWI76_RS04705 -2.7 -4.7 DNA-binding transcriptional regulator FruR compare
BWI76_RS01185 -2.6 -2.5 adenylate cyclase compare
BWI76_RS15825 -2.5 -3.7 hypothetical protein compare
BWI76_RS06185 -2.4 -9.6 shikimate kinase II compare
BWI76_RS01200 -2.3 -2.9 diaminopimelate epimerase compare
BWI76_RS23240 -2.3 -4.3 exonuclease V subunit gamma compare
BWI76_RS05015 -2.3 -4.1 transcriptional regulator compare
BWI76_RS16275 -2.3 -3.5 fumarate hydratase FumA compare
BWI76_RS26570 -2.3 -4.1 anion permease compare
BWI76_RS11520 -2.3 -1.5 hypothetical protein compare
BWI76_RS26055 -2.2 -5.9 siroheme synthase compare
BWI76_RS08520 -2.2 -4.2 colicin transporter TolQ compare
BWI76_RS00180 -2.2 -1.9 F0F1 ATP synthase subunit epsilon compare
BWI76_RS23480 -2.2 -11.4 EAL domain-containing protein compare
BWI76_RS09190 -2.2 -4.4 hypothetical protein compare
BWI76_RS26455 -2.2 -3.9 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS25320 -2.1 -7.0 glutamate synthase compare
BWI76_RS00960 -2.0 -7.3 acetolactate synthase 2 catalytic subunit compare
BWI76_RS08525 -2.0 -4.3 colicin transporter compare
BWI76_RS00140 -2.0 -1.5 phosphate transport system regulator PhoU compare
BWI76_RS20910 -1.8 -8.3 glycine cleavage system transcriptional repressor compare
BWI76_RS27820 -1.8 -1.9 ilvB operon leader peptide IvbL compare
BWI76_RS25315 -1.8 -9.6 glutamate synthase large subunit compare
BWI76_RS00345 -1.7 -3.6 protein disulfide oxidoreductase DsbA compare
BWI76_RS26460 -1.6 -4.2 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS17065 -1.6 -9.9 phosphoenolpyruvate synthase compare
BWI76_RS01070 -1.6 -5.6 thiol reductase thioredoxin compare
BWI76_RS27430 -1.6 -1.5 (p)ppGpp synthetase compare
BWI76_RS04555 -1.6 -10.3 citrate/acetate antiporter conserved
BWI76_RS17975 -1.6 -4.2 tail-specific protease compare
BWI76_RS27440 -1.6 -3.0 DNA helicase RecG compare
BWI76_RS00970 -1.5 -3.2 branched chain amino acid aminotransferase compare
BWI76_RS26075 -1.5 -4.5 DNA adenine methylase compare
BWI76_RS04545 -1.5 -6.9 two-component response regulator for citrate compare
BWI76_RS08530 -1.5 -2.7 protein TolA compare
BWI76_RS25925 -1.5 -3.5 hypothetical protein compare
BWI76_RS02530 -1.5 -1.6 tRNA dimethylallyltransferase compare
BWI76_RS23895 -1.5 -1.6 Xaa-Pro aminopeptidase compare
BWI76_RS19700 -1.5 -2.1 deoxyribonuclease IV compare
BWI76_RS07465 -1.4 -3.1 TetR family transcriptional regulator compare
BWI76_RS08980 -1.4 -1.5 DNA starvation/stationary phase protection protein compare
BWI76_RS27815 -1.4 -8.1 acetolactate synthase catalytic subunit compare
BWI76_RS14065 -1.4 -1.9 hypothetical protein compare
BWI76_RS25280 -1.4 -2.0 RNase adaptor protein RapZ compare
BWI76_RS05200 -1.4 -2.2 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS04550 -1.4 -6.7 two-component sensor kinase compare
BWI76_RS22805 -1.4 -5.8 GTP diphosphokinase compare
BWI76_RS17980 -1.3 -4.3 RNA chaperone ProQ compare
BWI76_RS25870 -1.3 -1.8 elongation factor Tu compare
BWI76_RS04530 -1.3 -2.2 peptidylprolyl isomerase SurA compare
BWI76_RS19600 -1.3 -6.2 hypothetical protein compare
BWI76_RS25420 -1.3 -4.5 malate dehydrogenase compare
BWI76_RS09870 -1.3 -5.0 aromatic amino acid aminotransferase compare
BWI76_RS22695 -1.2 -4.1 sulfate adenylyltransferase compare
BWI76_RS08535 -1.2 -2.2 translocation protein TolB compare
BWI76_RS21685 -1.2 -1.5 hypothetical protein compare
BWI76_RS22700 -1.2 -3.8 sulfate adenylyltransferase subunit 2 compare
BWI76_RS21325 -1.2 -3.4 hypothetical protein compare
BWI76_RS20440 -1.2 -1.5 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS09025 -1.2 -2.3 GntR family transcriptional regulator compare
BWI76_RS15830 -1.2 -2.6 hypothetical protein compare
BWI76_RS21370 -1.2 -2.0 ATP-dependent RNA helicase SrmB compare
BWI76_RS21480 -1.2 -2.6 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS23970 -1.2 -1.6 mechanosensitive ion channel protein MscS compare
BWI76_RS21100 -1.2 -2.2 nucleoside-diphosphate kinase compare
BWI76_RS18165 -1.2 -1.9 NUDIX pyrophosphatase compare
BWI76_RS12790 -1.2 -1.4 lactate dehydrogenase compare
BWI76_RS17195 -1.1 -2.5 hypothetical protein compare
BWI76_RS01800 -1.1 -2.9 glucose-6-phosphate isomerase compare
BWI76_RS26000 -1.1 -4.9 aspartate aminotransferase family protein compare
BWI76_RS19605 -1.1 -2.8 CidB/LrgB family autolysis modulator compare
BWI76_RS01275 -1.1 -3.2 LysR family transcriptional regulator compare
BWI76_RS06735 -1.1 -1.8 50S ribosomal protein L31 compare
BWI76_RS25645 -1.1 -4.0 shikimate dehydrogenase compare
BWI76_RS15810 -1.0 -5.0 hypothetical protein compare
BWI76_RS15760 -1.0 -1.7 hypothetical protein compare
BWI76_RS10530 -1.0 -1.5 GntR family transcriptional regulator with compare
BWI76_RS03225 -1.0 -4.9 transcriptional regulator compare
BWI76_RS08700 -1.0 -4.0 helix-turn-helix-type transcriptional regulator compare
BWI76_RS21810 -1.0 -1.7 universal stress protein compare
BWI76_RS16315 -1.0 -2.0 SirA-like protein compare
BWI76_RS07380 -1.0 -2.4 hypothetical protein compare
BWI76_RS04270 -1.0 -3.2 transaldolase compare
BWI76_RS09635 -1.0 -2.5 amino acid ABC transporter ATP-binding protein compare
BWI76_RS20650 -1.0 -1.6 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS20970 -1.0 -1.4 phosphoribosylglycinamide formyltransferase compare
BWI76_RS24955 -1.0 -1.9 hypothetical protein compare
BWI76_RS25920 -1.0 -1.8 peptidylprolyl isomerase compare
BWI76_RS23265 -1.0 -2.5 hypothetical protein compare
BWI76_RS05010 -0.9 -2.2 tRNA glutamyl-Q synthetase compare
BWI76_RS01350 -0.9 -0.8 NAD(P)H-flavin reductase compare
BWI76_RS01060 -0.9 -5.8 guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase compare
BWI76_RS26620 -0.9 -1.0 Fe-S biogenesis protein NfuA compare
BWI76_RS24900 -0.9 -1.4 DeoR family transcriptional regulator compare
BWI76_RS06530 -0.9 -3.9 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS27305 -0.9 -3.7 glycosyl transferase compare
BWI76_RS24485 -0.9 -1.5 bifunctional dihydroneopterin aldolase/7,8-dihydroneopterin epimerase compare
BWI76_RS21690 -0.9 -1.6 hypothetical protein compare
BWI76_RS16470 -0.9 -1.2 transcriptional repressor NemR compare
BWI76_RS06535 -0.9 -3.3 endopeptidase La compare
BWI76_RS08210 -0.9 -1.4 N-acetylglucosamine-6-phosphate deacetylase compare
BWI76_RS21000 -0.9 -3.9 exopolyphosphatase compare
BWI76_RS23930 -0.9 -3.1 transcriptional regulator ArgP compare
BWI76_RS27875 -0.9 -1.1 membrane protein compare
BWI76_RS15955 -0.9 -6.2 transcriptional regulator compare
BWI76_RS19010 -0.9 -2.1 polysaccharide pyruvyl transferase yvff compare
BWI76_RS17290 -0.9 -3.3 formyltetrahydrofolate deformylase compare
BWI76_RS16805 -0.9 -1.6 basic amino acid ABC transporter substrate-binding protein compare
BWI76_RS08975 -0.9 -1.8 amino acid ABC transporter substrate-binding protein compare
BWI76_RS15630 -0.9 -2.5 hypothetical protein compare
BWI76_RS15680 -0.9 -3.0 hypothetical protein compare
BWI76_RS00390 -0.9 -2.2 two-component system sensor histidine kinase NtrB compare
BWI76_RS01325 -0.9 -1.4 twin-arginine translocase subunit TatB compare


Specific Phenotypes

For 6 genes in this experiment

For carbon source Trisodium citrate dihydrate in Klebsiella michiganensis M5al

For carbon source Trisodium citrate dihydrate across organisms