Experiment set5IT042 for Pseudomonas fluorescens FW300-N2E2

Compare to:

LB with Cadmium chloride hemipentahydrate 0.00005 M

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_5069 -4.8 -5.6 putative Cytochrome bd2, subunit II compare
Pf6N2E2_5068 -4.5 -12.3 putative Cytochrome bd2, subunit I compare
Pf6N2E2_5014 -4.1 -2.1 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3948 -4.0 -12.3 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_3658 -3.5 -6.6 Lipid A core - O-antigen ligase and related enzymes compare
Pf6N2E2_3782 -3.1 -4.3 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3839 -3.0 -4.9 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_3610 -2.9 -5.6 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_5527 -2.7 -3.0 Cold shock protein CspC compare
Pf6N2E2_5508 -2.6 -2.5 Formyltetrahydrofolate deformylase (EC 3.5.1.10) compare
Pf6N2E2_3842 -2.5 -3.7 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_2700 -2.5 -6.8 Cysteine synthase (EC 2.5.1.47) compare
Pf6N2E2_2574 -2.4 -2.3 Flagellar synthesis regulator FleN compare
Pf6N2E2_2274 -2.4 -5.5 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_3661 -2.3 -4.4 hypothetical protein compare
Pf6N2E2_5316 -2.3 -1.6 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_3617 -2.3 -5.3 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
Pf6N2E2_2218 -2.2 -4.3 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_2674 -2.1 -1.8 FIG00953856: hypothetical protein compare
Pf6N2E2_3252 -2.0 -5.4 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_2219 -2.0 -1.7 Cell division trigger factor (EC 5.2.1.8) compare
Pf6N2E2_3171 -2.0 -1.7 hypothetical protein compare
Pf6N2E2_2217 -2.0 -4.4 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_3303 -1.9 -4.1 Sensor histidine kinase PrrB (RegB) (EC 2.7.3.-) compare
Pf6N2E2_5727 -1.9 -5.8 FIG00955360: hypothetical protein compare
Pf6N2E2_2080 -1.9 -2.1 hypothetical protein compare
Pf6N2E2_3659 -1.9 -4.6 Protein fixF compare
Pf6N2E2_5342 -1.9 -2.0 21 kDa hemolysin precursor compare
Pf6N2E2_5560 -1.9 -2.6 Sigma-54 dependent transcriptional regulator/sensory box protein compare
Pf6N2E2_5242 -1.8 -2.1 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_2586 -1.8 -2.2 Hpt domain protein compare
Pf6N2E2_2506 -1.8 -9.8 nucleotide sugar epimerase/dehydratase WbpM compare
Pf6N2E2_1089 -1.8 -2.0 Delta 1-piperideine-2-carboxylate reductase (EC 1.5.1.21) / Delta 1-pyrroline-2-carboxylate reductase (EC 1.5.1.1) compare
Pf6N2E2_2320 -1.8 -2.5 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
Pf6N2E2_3251 -1.8 -6.8 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_1056 -1.7 -1.1 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_3264 -1.7 -3.0 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_3460 -1.7 -1.6 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_4584 -1.7 -1.8 Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1) compare
Pf6N2E2_3253 -1.7 -4.3 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_2152 -1.6 -2.1 hypothetical protein compare
Pf6N2E2_5339 -1.6 -5.3 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_6085 -1.6 -1.4 Aha1 domain superfamily compare
Pf6N2E2_5160 -1.6 -2.1 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_4706 -1.5 -2.5 Electron transfer flavoprotein, beta subunit compare
Pf6N2E2_4187 -1.5 -3.5 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_3192 -1.5 -3.6 tRNA:Cm32/Um32 methyltransferase compare
Pf6N2E2_2064 -1.5 -3.7 Cobalt-precorrin-3b C17-methyltransferase compare
Pf6N2E2_6063 -1.5 -5.8 2-methylcitrate dehydratase FeS dependent (EC 4.2.1.79) compare
Pf6N2E2_4451 -1.5 -4.2 FIG139438: lipoprotein B compare
Pf6N2E2_4579 -1.5 -2.2 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_4803 -1.5 -1.7 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_3612 -1.4 -2.0 HflK protein compare
Pf6N2E2_3191 -1.4 -4.2 Serine acetyltransferase (EC 2.3.1.30) compare
Pf6N2E2_1656 -1.4 -2.2 hypothetical protein compare
Pf6N2E2_623 -1.4 -1.5 FIG00954674: hypothetical protein compare
Pf6N2E2_572 -1.4 -2.8 hypothetical protein compare
Pf6N2E2_5705 -1.4 -2.0 Sensor protein PhoQ (EC 2.7.13.3) compare
Pf6N2E2_2012 -1.4 -2.1 hypothetical protein compare
Pf6N2E2_204 -1.4 -1.5 hypothetical protein compare
Pf6N2E2_5052 -1.4 -2.2 Hydrolase in polyol utilization gene cluster, haloacid dehalogenase-like family compare
Pf6N2E2_5430 -1.3 -5.7 Transglycosylase, Slt family compare
Pf6N2E2_4454 -1.3 -4.1 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_3841 -1.3 -4.1 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_2509 -1.3 -2.2 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf6N2E2_4153 -1.3 -1.0 Sensory box histidine kinase compare
Pf6N2E2_2313 -1.3 -2.8 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
Pf6N2E2_2508 -1.3 -2.9 hypothetical protein compare
Pf6N2E2_3783 -1.3 -2.4 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_2870 -1.3 -2.7 Ribonuclease BN (EC 3.1.-.-) compare
Pf6N2E2_5558 -1.3 -6.1 Glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) (from data) compare
Pf6N2E2_451 -1.3 -2.4 transcriptional regulator MvaT, P16 subunit, putative compare
Pf6N2E2_2189 -1.2 -3.2 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_4691 -1.2 -2.0 hypothetical protein compare
Pf6N2E2_625 -1.2 -3.0 MoxR-like ATPase in aerotolerance operon compare
Pf6N2E2_1802 -1.2 -3.7 polysaccharide deacetylase compare
Pf6N2E2_3338 -1.2 -1.4 1-phosphofructokinase (EC 2.7.1.56) compare
Pf6N2E2_2180 -1.2 -2.4 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_649 -1.2 -2.1 General secretion pathway protein L compare
Pf6N2E2_4585 -1.2 -7.3 Cell division protein FtsX compare
Pf6N2E2_5647 -1.2 -4.0 Transcriptional regulator, TetR family compare
Pf6N2E2_1797 -1.2 -2.3 Transcriptional regulator compare
Pf6N2E2_2201 -1.2 -2.5 Transmembrane regulator protein PrtR compare
Pf6N2E2_5172 -1.2 -1.9 FOG: TPR repeat compare
Pf6N2E2_3351 -1.2 -3.3 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_479 -1.2 -3.5 Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase (EC 2.3.1.168) (from data) compare
Pf6N2E2_145 -1.2 -6.4 putative exported protein compare
Pf6N2E2_3261 -1.2 -3.5 hypothetical protein compare
Pf6N2E2_3475 -1.2 -1.4 hypothetical protein compare
Pf6N2E2_5505 -1.2 -2.2 hypothetical protein compare
Pf6N2E2_6064 -1.1 -3.9 2-methylaconitate isomerase compare
Pf6N2E2_4531 -1.1 -1.3 hypothetical protein compare
Pf6N2E2_4556 -1.1 -2.9 FIG00953078: hypothetical protein compare
Pf6N2E2_40 -1.1 -3.9 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_3908 -1.1 -4.1 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_1034 -1.1 -1.3 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_3529 -1.1 -1.7 Toxin A compare
Pf6N2E2_5455 -1.1 -2.8 hypothetical protein compare
Pf6N2E2_4128 -1.1 -2.8 hypothetical protein compare
Pf6N2E2_5605 -1.1 -2.6 FxsA protein compare
Pf6N2E2_2507 -1.1 -3.9 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
Pf6N2E2_5245 -1.1 -3.8 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_144 -1.1 -7.9 Uncharacterized protein YtfM precursor compare
Pf6N2E2_1463 -1.1 -1.9 Isochorismate pyruvate-lyase (EC 4.-.-.-) compare
Pf6N2E2_855 -1.1 -2.6 Transcriptional regulator, IclR family compare
Pf6N2E2_4921 -1.1 -2.6 3,4-dihydroxy-2-butanone 4-phosphate synthase (EC 4.1.99.12) / GTP cyclohydrolase II (EC 3.5.4.25) compare
Pf6N2E2_2312 -1.1 -1.2 Cytochrome c oxidase subunit CcoQ (EC 1.9.3.1) compare
Pf6N2E2_1783 -1.1 -2.2 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf6N2E2_6099 -1.1 -1.1 tRNA-Glu-TTC compare
Pf6N2E2_3349 -1.0 -2.0 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_1509 -1.0 -3.7 FIG00450070: hypothetical protein compare
Pf6N2E2_2261 -1.0 -3.8 VacJ-like lipoprotein precursor compare
Pf6N2E2_2309 -1.0 -2.2 hypothetical protein compare
Pf6N2E2_2527 -1.0 -2.4 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_2013 -1.0 -1.2 hypothetical protein compare
Pf6N2E2_5156 -1.0 -1.7 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_5557 -1.0 -5.2 L-serine ammonia-lyase (EC 4.3.1.17) (from data) compare
Pf6N2E2_1490 -1.0 -2.0 hypothetical protein compare
Pf6N2E2_2693 -1.0 -1.7 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_2479 -1.0 -1.8 Transcription elongation factor GreB compare
Pf6N2E2_5944 -1.0 -3.8 Ribosomal large subunit pseudouridine synthase C (EC 4.2.1.70) compare
Pf6N2E2_3480 -1.0 -1.4 Transcriptional regulator, ArsR family compare
Pf6N2E2_3940 -1.0 -5.3 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4928 -1.0 -1.1 Permeases of the major facilitator superfamily compare
Pf6N2E2_1626 -1.0 -4.0 Putative ATP-binding component of a transport system compare
Pf6N2E2_339 -1.0 -2.2 Glutathione-regulated potassium-efflux system protein KefC compare
Pf6N2E2_1743 -1.0 -2.3 Putrescine transport ATP-binding protein PotA (TC 3.A.1.11.1) compare
Pf6N2E2_4173 -1.0 -3.1 Methionine ABC transporter permease protein compare
Pf6N2E2_2822 -1.0 -4.5 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family compare
Pf6N2E2_3770 -1.0 -1.1 ATP-dependent hsl protease ATP-binding subunit HslU compare
Pf6N2E2_3786 -1.0 -1.7 Twin-arginine translocation protein TatC compare
Pf6N2E2_3573 -1.0 -1.9 HupE-UreJ family metal transporter compare
Pf6N2E2_1347 -1.0 -2.2 Oxidoreductase, short-chain dehydrogenase/reductase family (EC 1.1.1.-) compare
Pf6N2E2_2503 -0.9 -1.6 Glycosyl transferase, group 1 family protein compare
Pf6N2E2_2139 -0.9 -2.1 Paraquat-inducible protein A compare
Pf6N2E2_3257 -0.9 -2.0 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_2714 -0.9 -1.6 transcriptional regulator, Crp/Fnr family compare
Pf6N2E2_2825 -0.9 -2.4 RND efflux system, outer membrane lipoprotein CmeC compare
Pf6N2E2_5835 -0.9 -2.3 Pyruvate kinase (EC 2.7.1.40) compare
Pf6N2E2_302 -0.9 -3.6 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_828 -0.9 -2.8 Transcriptional regulator, TetR family compare
Pf6N2E2_58 -0.9 -1.4 tRNA-dihydrouridine synthase C (EC 1.-.-.-) compare
Pf6N2E2_600 -0.9 -2.0 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases compare
Pf6N2E2_2354 -0.9 -3.1 MxiH protein; Type III secretion cytoplasmic protein (YscF) compare
Pf6N2E2_3641 -0.9 -2.0 ADP-ribose pyrophosphatase (EC 3.6.1.13) compare
Pf6N2E2_4802 -0.9 -2.8 Thiosulfate sulfurtransferase GlpE (EC 2.8.1.1) compare
Pf6N2E2_5555 -0.9 -1.0 Cold shock protein CspA compare
Pf6N2E2_2176 -0.9 -1.4 Amidases related to nicotinamidase compare
Pf6N2E2_5169 -0.9 -2.5 FIG00954216: hypothetical protein compare
Pf6N2E2_5111 -0.9 -1.0 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf6N2E2_3840 -0.9 -2.7 FIG00956267: hypothetical protein compare
Pf6N2E2_82 -0.9 -2.1 hypothetical protein compare
Pf6N2E2_1516 -0.9 -2.6 transcriptional regulator, Crp/Fnr family compare
Pf6N2E2_3199 -0.9 -3.2 S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC 5.-.-.-) compare
Pf6N2E2_1691 -0.9 -1.6 hypothetical protein compare
Pf6N2E2_4263 -0.9 -2.0 Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family compare
Pf6N2E2_5086 -0.9 -1.0 hypothetical protein compare
Pf6N2E2_5338 -0.9 -4.1 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf6N2E2_1294 -0.9 -1.2 Carbon starvation protein A compare
Pf6N2E2_4364 -0.9 -1.4 Protein YicC compare
Pf6N2E2_4638 -0.9 -1.5 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_612 -0.8 -2.5 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) (from data) compare
Pf6N2E2_2755 -0.8 -1.2 Sigma factor RpoE negative regulatory protein RseA compare
Pf6N2E2_280 -0.8 -2.0 hypothetical protein compare
Pf6N2E2_4732 -0.8 -1.1 hypothetical protein compare
Pf6N2E2_5950 -0.8 -2.0 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_2125 -0.8 -1.4 hypothetical protein compare
Pf6N2E2_5331 -0.8 -3.2 ATPase, AFG1 family compare
Pf6N2E2_4159 -0.8 -2.1 Cytochrome c4 compare
Pf6N2E2_4372 -0.8 -2.2 FIG00460773: hypothetical protein compare
Pf6N2E2_2682 -0.8 -1.8 Transcriptional regulator, LysR family compare
Pf6N2E2_5103 -0.8 -0.9 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_5049 -0.8 -1.3 acetyltransferase, GNAT family compare
Pf6N2E2_4206 -0.8 -1.1 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_4775 -0.8 -3.5 Coenzyme PQQ synthesis protein B compare
Pf6N2E2_2984 -0.8 -1.4 LysR family transcriptional regulator PA3398 compare
Pf6N2E2_953 -0.8 -1.6 FIG00958851: hypothetical protein compare
Pf6N2E2_2938 -0.8 -1.7 Outer membrane lipoprotein compare
Pf6N2E2_1508 -0.8 -1.3 DNA-binding response regulator compare
Pf6N2E2_3847 -0.8 -2.2 FIG001341: Probable Fe(2+)-trafficking protein YggX compare
Pf6N2E2_5584 -0.8 -1.7 Bacterioferritin-associated ferredoxin compare
Pf6N2E2_955 -0.8 -2.0 FIG00953508: hypothetical protein compare
Pf6N2E2_4889 -0.8 -3.0 Putative transport protein compare
Pf6N2E2_3778 -0.8 -1.6 FIG00954300: hypothetical protein compare
Pf6N2E2_114 -0.8 -1.8 Polysaccharide biosynthesis protein compare
Pf6N2E2_5679 -0.8 -1.9 hypothetical protein compare
Pf6N2E2_1812 -0.8 -1.5 peptide ABC transporter, ATP-binding protein compare
Pf6N2E2_2514 -0.8 -2.5 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_4276 -0.8 -2.6 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_4362 -0.8 -0.9 DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) compare
Pf6N2E2_2424 -0.8 -2.5 Molybdopterin-guanine dinucleotide biosynthesis protein MobA compare
Pf6N2E2_3534 -0.8 -1.7 Cobalamin biosynthesis protein CobG compare
Pf6N2E2_1162 -0.8 -1.0 Transmembrane amino acid efflux protein compare
Pf6N2E2_3282 -0.8 -1.3 FIG005080: Possible exported protein compare
Pf6N2E2_1169 -0.8 -1.5 TnpR protein compare
Pf6N2E2_1634 -0.8 -2.4 ABC-type Fe3+-siderophore transport system, permease component compare
Pf6N2E2_4125 -0.8 -2.3 Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake compare
Pf6N2E2_3373 -0.8 -1.7 Outer membrane lipoprotein SmpA, a component of the essential YaeT outer-membrane protein assembly complex compare
Pf6N2E2_1636 -0.8 -3.7 Ferrichrome-iron receptor compare
Pf6N2E2_2124 -0.8 -0.8 Mg(2+) transport ATPase protein C compare


Specific Phenotypes

For 3 genes in this experiment

For stress Cadmium chloride hemipentahydrate in Pseudomonas fluorescens FW300-N2E2

For stress Cadmium chloride hemipentahydrate across organisms