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Experiment set5IT040 for
Methanococcus maripaludis S2
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Formate McCas no stress control 1
200 most important genes:
gene
name
fitness
t score
description
MMP
_RS03315
-4.8
-3.4
ferrous iron transport protein A
compare
MMP
_RS01175
-3.9
-9.4
triphosphoribosyl-dephospho-CoA synthase
compare
MMP
_RS06700
-3.9
-21.4
hypothetical protein
compare
MMP
_RS06680
-3.4
-23.6
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
compare
MMP
_RS02280
-3.1
-2.3
DUF211 domain-containing protein
compare
MMP
_RS06685
-2.7
-16.1
formate dehydrogenase H subunit alpha selenocysteine-containing
compare
MMP
_RS06355
-2.7
-5.3
molybdenum cofactor biosynthesis protein MoaE
compare
MMP
_RS01005
-2.6
-3.3
riboflavin synthase
compare
MMP
_RS07635
-2.6
-9.8
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMP
_RS06715
-2.6
-18.7
cache domain-containing protein
compare
MMP
_RS08820
-2.5
-8.2
hypothetical protein
compare
MMP
_RS06345
-2.4
-16.9
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMP
_RS03015
-2.4
-14.8
GTP 3' 8-cyclase MoaA
compare
MMP
_RS02010
-2.4
-11.6
PHP domain-containing protein
compare
MMP
_RS06720
-2.4
-8.9
response regulator transcription factor
compare
MMP
_RS05515
-2.4
-15.8
cyclic pyranopterin monophosphate synthase MoaC
compare
MMP
_RS00300
-2.3
-1.5
6 7-dimethyl-8-ribityllumazine synthase
compare
MMP
_RS01755
-2.3
-2.7
DUF2097 domain-containing protein
compare
MMP
_RS06350
-2.3
-12.6
HesA/MoeB/ThiF family protein
compare
MMP
_RS06730
-2.2
-4.3
phosphopantothenate/pantothenate synthetase
compare
MMP
_RS06295
-2.2
-8.5
methanogenesis marker 14 protein
compare
MMP
_RS01020
-2.2
-2.5
3 4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMP
_RS04780
-2.2
-4.9
ribonuclease P
compare
MMP
_RS00895
-2.1
-6.1
hypothetical protein
compare
MMP
_RS06705
-2.1
-7.2
formate/nitrite transporter family protein
compare
MMP
_RS03025
-2.1
-6.8
molybdenum cofactor guanylyltransferase
compare
MMP
_RS08460
-2.1
-3.7
proteasome-activating nucleotidase
compare
MMP
_RS01500
-2.1
-3.9
CBS domain-containing protein
compare
MMP
_RS01265
-2.0
-3.8
hypothetical protein
compare
MMP
_RS07600
-2.0
-5.8
Ni-sirohydrochlorin a c-diamide synthase
compare
MMP
_RS02355
-2.0
-4.5
30S ribosomal protein S27ae
compare
MMP
_RS07445
-1.9
-6.4
helix-turn-helix domain-containing protein
compare
MMP
_RS02195
-1.9
-6.6
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
compare
MMP
_RS00115
-1.9
-14.6
radical SAM protein
compare
MMP
_RS00695
-1.8
-1.6
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMP
_RS07575
-1.8
-7.1
RNA ligase partner protein
compare
MMP
_RS00685
-1.8
-6.1
2-phospho-L-lactate guanylyltransferase
compare
MMP
_RS00110
-1.8
-3.3
hypothetical protein
compare
MMP
_RS08210
-1.8
-3.8
phosphatidylglycerophosphatase A
compare
MMP
_RS06625
-1.7
-4.1
DNA primase
compare
MMP
_RS06315
-1.7
-2.0
cobalt-precorrin-7 (C(5))-methyltransferase
compare
MMP
_RS03435
-1.7
-3.5
ketol-acid reductoisomerase
compare
MMP
_RS08300
-1.7
-2.2
metal-sulfur cluster assembly factor
compare
MMP
_RS05875
-1.7
-5.3
hydroxyethylthiazole kinase
compare
MMP
_RS05555
-1.7
-2.9
DUF4040 domain-containing protein
compare
MMP
_RS08745
-1.7
-7.1
CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMP
_RS05550
-1.7
-1.5
cation:proton antiporter
compare
MMP
_RS06230
-1.7
-3.7
helix-turn-helix domain-containing protein
compare
MMP
_RS07765
-1.6
-10.2
sodium:alanine symporter family protein
compare
MMP
_RS07005
-1.6
-1.1
4Fe-4S binding protein
compare
MMP
_RS07630
-1.6
-2.5
ATP-binding cassette domain-containing protein
compare
MMP
_RS04775
-1.6
-4.7
adenosylhomocysteinase
compare
MMP
_RS00295
-1.6
-4.5
gamma carbonic anhydrase family protein
compare
MMP
_RS01610
-1.6
-5.0
hypothetical protein
compare
MMP
_RS03600
-1.5
-3.3
triose-phosphate isomerase
compare
MMP
_RS03035
-1.5
-4.6
4-hydroxy-tetrahydrodipicolinate synthase
compare
MMP
_RS04890
-1.5
-1.2
adenylyltransferase/cytidyltransferase family protein
compare
MMP
_RS01220
-1.5
-8.6
hypothetical protein
compare
MMP
_RS06270
-1.5
-5.4
TIGR00300 family protein
compare
MMP
_RS02240
-1.5
-5.3
methanogenesis marker 7 protein
compare
MMP
_RS02800
-1.5
-6.1
nucleotidyltransferase domain-containing protein
compare
MMP
_RS01325
-1.4
-3.3
dihydroneopterin aldolase family protein
compare
MMP
_RS02135
-1.4
-3.6
DUF5612 domain-containing protein
compare
MMP
_RS07845
-1.4
-3.5
LL-diaminopimelate aminotransferase
compare
MMP
_RS04585
-1.4
-7.8
AIR synthase related protein
compare
MMP
_RS07755
-1.4
-2.0
DUF555 domain-containing protein
compare
MMP
_RS07735
-1.4
-1.6
2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
compare
MMP
_RS07525
-1.4
-7.6
4Fe-4S binding protein
compare
MMP
_RS03640
-1.4
-5.6
archaeal proteasome endopeptidase complex subunit beta
compare
MMP
_RS07545
-1.4
-1.8
HTH domain-containing protein
compare
MMP
_RS07380
-1.4
-2.8
transcription elongation factor Spt5
compare
MMP
_RS01385
-1.4
-1.2
imidazole glycerol phosphate synthase subunit HisH
compare
MMP
_RS06340
-1.3
-6.5
phosphoadenosine phosphosulfate reductase family protein
compare
MMP
_RS05510
-1.3
-5.3
Rrf2 family transcriptional regulator
compare
MMP
_RS06865
-1.3
-2.5
HypC/HybG/HupF family hydrogenase formation chaperone
compare
MMP
_RS02900
-1.3
-0.9
imidazoleglycerol-phosphate dehydratase HisB
compare
MMP
_RS00320
-1.3
-2.4
class I SAM-dependent methyltransferase
compare
MMP
_RS03400
-1.3
-3.0
archease
compare
MMP
_RS06925
-1.3
-3.0
ribonuclease VapC4
compare
MMP
_RS05845
-1.3
-2.4
tRNA-intron lyase
compare
MMP
_RS08320
-1.2
-8.1
molybdopterin molybdotransferase MoeA
compare
MMP
_RS06020
-1.2
-4.7
archaeoflavoprotein AfpA
compare
MMP
_RS07580
-1.2
-3.0
DUF356 domain-containing protein
compare
MMP
_RS01980
-1.2
-9.2
trimeric intracellular cation channel family protein
compare
MMP
_RS00735
-1.2
-4.0
5 10-methenyltetrahydromethanopterin hydrogenase
compare
MMP
_RS05540
-1.2
-3.7
hypothetical protein
compare
MMP
_RS04685
-1.2
-3.8
DUF126 domain-containing protein
compare
MMP
_RS02235
-1.2
-8.9
CBS domain-containing protein
compare
MMP
_RS05920
-1.1
-1.1
50S ribosomal protein L37e
compare
MMP
_RS06885
-1.1
-2.8
50S ribosome-binding GTPase
compare
MMP
_RS08720
-1.1
-1.8
4Fe-4S binding protein
compare
MMP
_RS06475
-1.1
-3.6
FAD-dependent oxidoreductase
compare
MMP
_RS00515
-1.1
-1.5
DUF655 domain-containing protein
compare
MMP
_RS01225
-1.1
-5.1
DUF5379 domain-containing protein
compare
MMP
_RS02165
-1.1
-5.7
tRNA-dihydrouridine synthase
compare
MMP
_RS06105
-1.1
-7.5
hydrogenase maturation peptidase HycI
compare
MMP
_RS01365
-1.1
-3.3
archaeal proteasome endopeptidase complex subunit alpha
compare
MMP
_RS03475
-1.1
-0.8
hypothetical protein
compare
MMP
_RS07385
-1.1
-1.9
protein translocase SEC61 complex subunit gamma
compare
MMP
_RS01800
-1.0
-3.6
TIGR00303 family protein
compare
MMP
_RS07750
-1.0
-4.3
DUF357 domain-containing protein
compare
MMP
_RS00315
-1.0
-5.8
Nif3-like dinuclear metal center hexameric protein
compare
MMP
_RS07700
-1.0
-6.5
DUF1188 domain-containing protein
compare
MMP
_RS02875
-1.0
-6.2
chorismate pyruvate-lyase family protein
compare
MMP
_RS03580
-1.0
-3.5
signal recognition particle-docking protein FtsY
compare
MMP
_RS08645
-1.0
-5.3
UPF0179 family protein
compare
MMP
_RS06285
-1.0
-3.0
precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
compare
MMP
_RS06400
-1.0
-1.9
4Fe-4S binding protein
compare
MMP
_RS02885
-1.0
-7.9
molybdopterin biosynthesis protein
compare
MMP
_RS08435
-1.0
-2.7
Era-like GTP-binding protein
compare
MMP
_RS07200
-0.9
-4.3
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMP
_RS06120
-0.9
-1.8
UPF0147 family protein
compare
MMP
_RS00730
-0.9
-5.4
5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
compare
MMP
_RS08715
-0.9
-1.9
formylmethanofuran dehydrogenase subunit B
compare
MMP
_RS08330
-0.9
-4.9
NADH-quinone oxidoreductase subunit H
compare
MMP
_RS04605
-0.9
-4.6
cobalt ECF transporter T component CbiQ
compare
MMP
_RS07775
-0.9
-5.4
alanine dehydrogenase
compare
MMP
_RS09020
-0.9
-1.8
hypothetical protein
compare
MMP
_RS05245
-0.9
-5.9
archaeosine biosynthesis radical SAM protein RaSEA
compare
MMP
_RS01720
-0.9
-1.0
replication factor C large subunit
compare
MMP
_RS06895
-0.9
-2.1
selenocysteine-specific translation elongation factor
compare
MMP
_RS07730
-0.9
-1.3
pyruvate synthase subunit beta
compare
MMP
_RS08725
-0.9
-1.9
Ni/Fe hydrogenase subunit alpha
compare
MMP
_RS01380
-0.9
-2.7
PHP domain-containing protein
compare
MMP
_RS03305
-0.8
-5.0
winged helix-turn-helix domain-containing protein
compare
MMP
_RS00290
-0.8
-4.2
hypothetical protein
compare
MMP
_RS08915
-0.8
-1.7
2 5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase
compare
MMP
_RS07605
-0.8
-2.8
diadenylate cyclase
compare
MMP
_RS01250
-0.8
-4.0
tRNA (guanine(26)-N(2))-dimethyltransferase
compare
MMP
_RS03960
-0.8
-0.9
hypothetical protein
compare
MMP
_RS05765
-0.8
-3.5
M42 family metallopeptidase
compare
MMP
_RS08165
-0.8
-1.3
phosphoglycerate dehydrogenase
compare
MMP
_RS03555
-0.8
-5.6
transcriptional regulator
compare
MMP
_RS04850
-0.8
-6.8
UPF0254 family protein
compare
MMP
_RS08200
-0.8
-7.4
archaeosine synthase subunit alpha
compare
MMP
_RS05545
-0.8
-5.2
pyridoxal phosphate-dependent aminotransferase
compare
MMP
_RS00305
-0.8
-1.7
phosphoribosyl-ATP diphosphatase
compare
MMP
_RS01985
-0.8
-4.6
F420-dependent methylenetetrahydromethanopterin dehydrogenase
compare
MMP
_RS01795
-0.8
-1.8
methanogenesis marker 6 protein
compare
MMP
_RS03205
-0.8
-0.9
peptidyl-tRNA hydrolase Pth2
compare
MMP
_RS07625
-0.8
-2.1
cobalt ECF transporter T component CbiQ
compare
MMP
_RS02190
-0.7
-1.5
sulfopyruvate decarboxylase subunit alpha
compare
MMP
_RS06630
-0.7
-1.1
UPF0058 family protein
compare
MMP
_RS00725
-0.7
-4.0
5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
compare
MMP
_RS03445
-0.7
-1.2
methanogenesis marker 17 protein
compare
MMP
_RS04615
-0.7
-3.4
PDGLE domain-containing protein
compare
MMP
_RS06200
-0.7
-4.9
M24 family metallopeptidase
compare
MMP
_RS05445
-0.7
-4.5
CoB--CoM heterodisulfide reductase subunit B
compare
MMP
_RS00720
-0.7
-4.6
metal-dependent hydrolase
compare
MMP
_RS06175
-0.7
-4.9
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS06215
-0.7
-2.0
30S ribosomal protein S6e
compare
MMP
_RS05430
-0.7
-3.8
TIGR00288 family NYN domain-containing protein
compare
MMP
_RS04875
-0.7
-2.4
energy-converting hydrogenase B subunit P
compare
MMP
_RS00620
-0.7
-5.5
4Fe-4S binding protein
compare
MMP
_RS04870
-0.7
-2.1
TIGR02253 family HAD-type hydrolase
compare
MMP
_RS07535
-0.7
-4.2
4Fe-4S binding protein
compare
MMP
_RS06395
-0.7
-2.9
ThiF family adenylyltransferase
compare
MMP
_RS05345
-0.7
-3.6
hypothetical protein
compare
MMP
_RS02145
-0.7
-2.9
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS03095
-0.7
-3.6
diphthine synthase
compare
MMP
_RS07425
-0.7
-3.6
GTP-binding protein
compare
MMP
_RS08070
-0.7
-3.3
DUF2096 domain-containing protein
compare
MMP
_RS01195
-0.7
-1.4
metalloregulator ArsR/SmtB family transcription factor
compare
MMP
_RS04955
-0.7
-2.9
DNA topoisomerase I
compare
MMP
_RS03155
-0.7
-4.3
precorrin-6A reductase
compare
MMP
_RS00120
-0.7
-4.2
LysR family transcriptional regulator
compare
MMP
_RS07350
-0.6
-1.8
preprotein translocase subunit Sec61beta
compare
MMP
_RS08790
-0.6
-1.2
translation initiation factor IF-2 subunit alpha
compare
MMP
_RS07695
-0.6
-3.0
DUF3236 domain-containing protein
compare
MMP
_RS03490
-0.6
-1.9
DUF2115 domain-containing protein
compare
MMP
_RS01240
-0.6
-0.7
7-cyano-7-deazaguanine synthase QueC
compare
MMP
_RS05095
-0.6
-4.0
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMP
_RS08635
-0.6
-1.2
UbiA family prenyltransferase
compare
MMP
_RS05815
-0.6
-2.0
NOL1/NOP2/sun family putative RNA methylase
compare
MMP
_RS00050
-0.6
-3.9
AarF/UbiB family protein
compare
MMP
_RS01030
-0.6
-2.4
MTAP family purine nucleoside phosphorylase
compare
MMP
_RS01180
-0.6
-0.9
XTP/dITP diphosphatase
compare
MMP
_RS04720
-0.6
-1.5
DedA family protein
compare
MMP
_RS05440
-0.6
-3.8
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS02340
-0.6
-1.2
DNA-directed RNA polymerase subunit E''
compare
MMP
_RS05060
-0.6
-4.8
AAA family ATPase
compare
MMP
_RS01665
-0.6
-2.1
DUF2111 domain-containing protein
compare
MMP
_RS04620
-0.5
-4.0
cobalt transporter CbiM
compare
MMP
_RS05265
-0.5
-1.6
2-isopropylmalate synthase
compare
MMP
_RS00475
-0.5
-3.1
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
compare
MMP
_RS00915
-0.5
-2.7
DUF116 domain-containing protein
compare
MMP
_RS07365
-0.5
-4.1
2-phosphoglycerate kinase
compare
MMP
_RS07555
-0.5
-0.6
monovalent cation/H+ antiporter subunit E
compare
MMP
_RS01830
-0.5
-1.4
tRNA-Val
compare
MMP
_RS01100
-0.5
-1.3
ABC transporter ATP-binding protein
compare
MMP
_RS03300
-0.5
-0.8
TOBE domain-containing protein
compare
MMP
_RS01780
-0.5
-4.2
TrmJ/YjtD family RNA methyltransferase
compare
MMP
_RS01700
-0.5
-0.7
dihydroxy-acid dehydratase
compare
MMP
_RS05930
-0.5
-1.7
3-isopropylmalate dehydratase large subunit
compare
MMP
_RS06855
-0.5
-3.5
hypothetical protein
compare
MMP
_RS08240
-0.5
-3.3
methanogenesis marker 16 metalloprotein
compare
MMP
_RS05055
-0.5
-4.5
DUF166 domain-containing protein
compare
MMP
_RS05090
-0.5
-4.3
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
MMP
_RS02245
-0.5
-2.1
hypothetical protein
compare
MMP
_RS06370
-0.5
-1.9
biotin synthase BioB
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis S2 in stress experiments