Experiment set5IT040 for Klebsiella michiganensis M5al

Compare to:

D-Gluconic Acid sodium salt carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS18930 -9.0 -5.5 histidinol-phosphate transaminase compare
BWI76_RS04160 -8.5 -5.9 phosphoserine phosphatase compare
BWI76_RS18935 -8.3 -5.7 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS22755 -7.9 -5.5 phosphoadenosine phosphosulfate reductase compare
BWI76_RS23220 -7.6 -5.3 amino-acid N-acetyltransferase compare
BWI76_RS18950 -7.6 -5.2 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS00805 -7.5 -5.2 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS18925 -7.4 -5.1 histidinol dehydrogenase compare
BWI76_RS09755 -7.3 -5.0 phosphoserine transaminase compare
BWI76_RS02995 -6.9 -6.7 aspartate carbamoyltransferase compare
BWI76_RS05840 -6.9 -4.7 glutamate 5-kinase compare
BWI76_RS25115 -6.7 -6.5 argininosuccinate synthase compare
BWI76_RS21475 -6.7 -7.8 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS00990 -6.5 -7.7 ketol-acid reductoisomerase compare
BWI76_RS23920 -6.4 -4.4 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS21465 -6.4 -6.2 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS04250 -6.4 -7.5 homoserine kinase compare
BWI76_RS04675 -6.3 -7.5 3-isopropylmalate dehydrogenase compare
BWI76_RS00855 -6.2 -7.4 argininosuccinate lyase compare
BWI76_RS05835 -6.2 -4.3 gamma-glutamyl-phosphate reductase compare
BWI76_RS04470 -6.1 -10.3 carbamoyl phosphate synthase large subunit compare
BWI76_RS20895 -6.0 -5.9 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS04680 -5.9 -13.7 2-isopropylmalate synthase compare
BWI76_RS08385 -5.8 -3.1 citrate (Si)-synthase compare
BWI76_RS04245 -5.7 -14.1 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS07070 -5.6 -5.4 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS01615 -5.6 -11.8 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS00835 -5.6 -13.9 phosphoenolpyruvate carboxylase compare
BWI76_RS20355 -5.5 -3.9 colicin V production protein compare
BWI76_RS26085 -5.5 -3.5 3-dehydroquinate synthase compare
BWI76_RS04465 -5.4 -5.2 carbamoyl-phosphate synthase small subunit compare
BWI76_RS09760 -5.4 -6.9 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS10990 -5.4 -3.0 dihydroorotase compare
BWI76_RS27385 -5.4 -6.4 orotate phosphoribosyltransferase compare
BWI76_RS24285 -5.3 -7.5 cystathionine beta-lyase compare
BWI76_RS11840 -5.3 -2.6 tryptophan synthase subunit alpha compare
BWI76_RS04255 -5.3 -6.5 threonine synthase compare
BWI76_RS18940 -5.2 -6.2 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS04685 -5.2 -9.9 putative leucine operon leader peptide compare
BWI76_RS11855 -5.1 -6.6 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS07065 -5.1 -8.1 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS00845 -5.1 -6.7 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS11850 -5.1 -8.0 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS04665 -5.0 -14.3 3-isopropylmalate dehydratase small subunit compare
BWI76_RS09645 -4.9 -1.8 thioredoxin-disulfide reductase compare
BWI76_RS18955 -4.9 -4.4 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS00850 -4.8 -7.2 acetylglutamate kinase compare
BWI76_RS01610 -4.8 -6.6 phosphoribosylamine--glycine ligase compare
BWI76_RS00965 -4.8 -1.8 acetolactate synthase 2 small subunit compare
BWI76_RS11965 -4.7 -4.3 orotidine-5'-phosphate decarboxylase compare
BWI76_RS04670 -4.6 -7.1 3-isopropylmalate dehydratase large subunit compare
BWI76_RS09910 -4.6 -16.1 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS22765 -4.5 -12.5 sulfite reductase subunit alpha compare
BWI76_RS03010 -4.4 -6.5 ornithine carbamoyltransferase compare
BWI76_RS00785 -4.4 -6.7 cystathionine gamma-synthase compare
BWI76_RS18920 -4.4 -4.1 ATP phosphoribosyltransferase compare
BWI76_RS21265 -4.3 -10.0 phosphoribosylformylglycinamidine synthase compare
BWI76_RS22760 -4.3 -10.0 sulfite reductase subunit beta compare
BWI76_RS04240 -4.3 -1.8 thr operon leader peptide compare
BWI76_RS23365 -4.3 -7.2 LysR family transcriptional regulator compare
BWI76_RS00985 -4.2 -8.0 transcriptional regulator IlvY compare
BWI76_RS01655 -4.2 -6.6 homoserine O-succinyltransferase compare
BWI76_RS00980 -4.2 -11.6 PLP-dependent threonine dehydratase compare
BWI76_RS20965 -4.2 -5.1 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS23360 -4.1 -2.5 diaminopimelate decarboxylase compare
BWI76_RS11860 -4.0 -7.0 anthranilate synthase component I compare
BWI76_RS00975 -4.0 -5.4 dihydroxy-acid dehydratase compare
BWI76_RS01200 -4.0 -2.7 diaminopimelate epimerase compare
BWI76_RS09660 -3.8 -2.6 DNA translocase FtsK compare
BWI76_RS20350 -3.7 -8.0 amidophosphoribosyltransferase compare
BWI76_RS23240 -3.6 -3.4 exonuclease V subunit gamma compare
BWI76_RS04645 -3.5 -3.5 3-dehydroquinase compare
BWI76_RS27390 -3.5 -4.2 ribonuclease PH compare
BWI76_RS11845 -3.5 -3.2 tryptophan synthase subunit beta compare
BWI76_RS00400 -3.4 -2.0 glutamine synthetase compare
BWI76_RS22690 -3.4 -5.0 adenylyl-sulfate kinase compare
BWI76_RS25645 -3.3 -8.2 shikimate dehydrogenase compare
BWI76_RS02735 -3.2 -5.5 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS20970 -3.2 -2.1 phosphoribosylglycinamide formyltransferase compare
BWI76_RS05015 -3.2 -3.1 transcriptional regulator compare
BWI76_RS01185 -3.2 -2.2 adenylate cyclase compare
BWI76_RS23230 -3.1 -3.0 exodeoxyribonuclease V subunit beta compare
BWI76_RS26000 -3.1 -8.8 aspartate aminotransferase family protein compare
BWI76_RS22805 -3.1 -9.1 GTP diphosphokinase compare
BWI76_RS01210 -2.9 -2.0 tyrosine recombinase XerC compare
BWI76_RS04270 -2.7 -4.7 transaldolase compare
BWI76_RS26055 -2.7 -7.6 siroheme synthase compare
BWI76_RS25320 -2.7 -6.1 glutamate synthase compare
BWI76_RS00180 -2.6 -2.0 F0F1 ATP synthase subunit epsilon compare
BWI76_RS02580 -2.6 -2.0 23S rRNA (guanosine(2251)-2'-O)-methyltransferase compare
BWI76_RS25315 -2.5 -9.8 glutamate synthase large subunit compare
BWI76_RS09670 -2.5 -4.1 recombination factor protein RarA compare
BWI76_RS26615 -2.4 -6.6 gluconate:H+ symporter (from data) conserved
BWI76_RS00140 -2.4 -1.5 phosphate transport system regulator PhoU compare
BWI76_RS21070 -2.2 -2.5 outer membrane protein assembly factor BamB compare
BWI76_RS02530 -2.1 -2.3 tRNA dimethylallyltransferase compare
BWI76_RS06185 -2.1 -6.0 shikimate kinase II compare
BWI76_RS15825 -2.1 -3.0 hypothetical protein compare
BWI76_RS00960 -2.0 -7.4 acetolactate synthase 2 catalytic subunit compare
BWI76_RS07725 -2.0 -1.6 iron-enterobactin transporter permease compare
BWI76_RS23480 -2.0 -10.4 EAL domain-containing protein compare
BWI76_RS20440 -2.0 -2.0 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS00390 -2.0 -4.4 two-component system sensor histidine kinase NtrB compare
BWI76_RS00385 -1.9 -7.2 nitrogen assimilation regulatory protein compare
BWI76_RS18100 -1.9 -8.2 phosphogluconate dehydratase conserved
BWI76_RS20375 -1.9 -2.6 membrane protein compare
BWI76_RS25960 -1.9 -4.8 NUDIX hydrolase compare
BWI76_RS20640 -1.9 -4.0 cysteine synthase A compare
BWI76_RS10745 -1.8 -1.3 hypothetical protein compare
BWI76_RS26570 -1.8 -3.2 anion permease compare
BWI76_RS16315 -1.8 -2.3 SirA-like protein compare
BWI76_RS04530 -1.8 -2.3 peptidylprolyl isomerase SurA compare
BWI76_RS07465 -1.7 -2.9 TetR family transcriptional regulator compare
BWI76_RS21140 -1.7 -3.2 molecular chaperone HscA compare
BWI76_RS02985 -1.7 -2.6 reactive intermediate/imine deaminase compare
BWI76_RS00345 -1.7 -3.0 protein disulfide oxidoreductase DsbA compare
BWI76_RS15845 -1.6 -1.4 hypothetical protein compare
BWI76_RS08205 -1.6 -4.6 DNA-binding transcriptional dual regulator NagC compare
BWI76_RS22695 -1.6 -4.2 sulfate adenylyltransferase compare
BWI76_RS26890 -1.5 -1.1 hypothetical protein compare
BWI76_RS20650 -1.5 -1.8 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS19025 -1.5 -7.2 phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating) compare
BWI76_RS05200 -1.5 -2.3 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS26075 -1.5 -2.0 DNA adenine methylase compare
BWI76_RS27440 -1.5 -3.6 DNA helicase RecG compare
BWI76_RS17980 -1.5 -5.3 RNA chaperone ProQ compare
BWI76_RS26455 -1.4 -2.7 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS27875 -1.4 -1.5 membrane protein compare
BWI76_RS22700 -1.4 -5.5 sulfate adenylyltransferase subunit 2 compare
BWI76_RS01275 -1.4 -4.5 LysR family transcriptional regulator compare
BWI76_RS15215 -1.4 -1.0 N-acetyltransferase compare
BWI76_RS18165 -1.4 -1.4 NUDIX pyrophosphatase compare
BWI76_RS04955 -1.3 -1.4 hypoxanthine phosphoribosyltransferase compare
BWI76_RS23265 -1.3 -2.9 hypothetical protein compare
BWI76_RS01675 -1.3 -2.4 putative cytoplasmic protein compare
BWI76_RS13980 -1.3 -1.4 hypothetical protein compare
BWI76_RS20995 -1.3 -2.6 RNA degradosome polyphosphate kinase compare
BWI76_RS04715 -1.2 -1.6 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS21115 -1.2 -3.1 3-mercaptopyruvate sulfurtransferase compare
BWI76_RS27430 -1.2 -1.1 (p)ppGpp synthetase compare
BWI76_RS06525 -1.2 -3.2 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS17805 -1.2 -1.0 membrane protein compare
BWI76_RS21285 -1.2 -1.5 HAD family hydrolase compare
BWI76_RS17100 -1.2 -1.9 glutathione peroxidase compare
BWI76_RS25160 -1.2 -1.5 transcription elongation factor GreA compare
BWI76_RS02410 -1.2 -1.6 EF-P beta-lysylation protein EpmB compare
BWI76_RS22125 -1.2 -3.2 membrane protein compare
BWI76_RS20435 -1.2 -1.0 chorismate synthase compare
BWI76_RS11040 -1.2 -2.7 ribonuclease E compare
BWI76_RS25505 -1.2 -3.5 RNase E specificity factor CsrD compare
BWI76_RS26460 -1.1 -2.5 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS17975 -1.1 -2.6 tail-specific protease compare
BWI76_RS18565 -1.1 -1.8 pemk protein compare
BWI76_RS18870 -1.1 -1.1 protein NifZ compare
BWI76_RS19690 -1.1 -1.6 LysR family transcriptional regulator compare
BWI76_RS21480 -1.1 -2.7 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS26805 -1.1 -1.4 cellulose biosynthesis protein BcsF compare
BWI76_RS09050 -1.1 -1.6 MFS transporter compare
BWI76_RS04705 -1.1 -2.3 DNA-binding transcriptional regulator FruR compare
BWI76_RS15835 -1.1 -0.7 hypothetical protein compare
BWI76_RS27350 -1.1 -3.2 hypothetical protein compare
BWI76_RS19240 -1.1 -1.4 ABC transporter substrate-binding protein compare
BWI76_RS25600 -1.1 -0.9 tRNA-Thr compare
BWI76_RS11430 -1.0 -0.8 lipoprotein compare
BWI76_RS04915 -1.0 -2.8 hypothetical protein compare
BWI76_RS00450 -1.0 -2.3 formate dehydrogenase accessory protein FdhE compare
BWI76_RS16455 -1.0 -1.6 superoxide dismutase compare
BWI76_RS12070 -1.0 -0.9 hypothetical protein compare
BWI76_RS26015 -1.0 -1.8 DUF2559 domain-containing protein compare
BWI76_RS11170 -1.0 -1.0 hypothetical protein compare
BWI76_RS17195 -1.0 -1.9 hypothetical protein compare
BWI76_RS16760 -1.0 -2.2 lipase compare
BWI76_RS17300 -1.0 -1.7 tRNA-Tyr compare
BWI76_RS02420 -1.0 -2.3 entericidin EcnAB compare
BWI76_RS19850 -1.0 -2.0 tRNA-Pro compare
BWI76_RS02855 -1.0 -2.0 cytochrome B562 compare
BWI76_RS06545 -1.0 -2.9 peptidylprolyl isomerase compare
BWI76_RS11435 -1.0 -1.2 hypothetical protein compare
BWI76_RS27820 -1.0 -1.1 ilvB operon leader peptide IvbL compare
BWI76_RS17290 -1.0 -2.9 formyltetrahydrofolate deformylase compare
BWI76_RS15955 -1.0 -5.4 transcriptional regulator compare
BWI76_RS17775 -1.0 -2.5 hypothetical protein compare
BWI76_RS21660 -1.0 -1.2 antirestriction protein compare
BWI76_RS22960 -1.0 -1.8 YgdI/YgdR family lipoprotein compare
BWI76_RS10040 -0.9 -1.5 heat-shock protein HspQ compare
BWI76_RS16920 -0.9 -1.2 3-(2,3-dihydroxyphenyl)propionate dioxygenase compare
BWI76_RS04525 -0.9 -1.5 4-hydroxythreonine-4-phosphate dehydrogenase PdxA compare
BWI76_RS06080 -0.9 -2.0 taurine dioxygenase compare
BWI76_RS20695 -0.9 -1.5 sulfate/thiosulfate transporter permease subunit compare
BWI76_RS00060 -0.9 -2.0 N-acetylneuraminate lyase compare
BWI76_RS08405 -0.9 -1.3 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS09530 -0.9 -0.9 hypothetical protein compare
BWI76_RS18605 -0.9 -1.6 oxidoreductase molybdopterin-binding protein compare
BWI76_RS06400 -0.9 -1.4 oxidative-stress-resistance chaperone compare
BWI76_RS01775 -0.9 -0.9 hypothetical protein compare
BWI76_RS04605 -0.9 -1.0 thiamine ABC transporter ATP-binding protein compare
BWI76_RS10755 -0.9 -1.0 pyrimidine utilization flavin reductase protein F compare
BWI76_RS09630 -0.9 -1.9 leucyl/phenylalanyl-tRNA--protein transferase compare
BWI76_RS15340 -0.9 -2.4 urea ABC transporter substrate-binding protein compare
BWI76_RS26395 -0.9 -2.0 cell division protein FtsE compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source D-Gluconic Acid sodium salt in Klebsiella michiganensis M5al

For carbon source D-Gluconic Acid sodium salt across organisms