Experiment set5IT039 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS01175		-4.4	-6.5	triphosphoribosyl-dephospho-CoA synthase
MMP_RS06700		-3.9	-18.0	hypothetical protein
MMP_RS02280		-3.6	-2.5	DUF211 domain-containing protein
MMP_RS01020		-3.4	-2.8	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS06680		-3.4	-21.8	Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
MMP_RS06685		-3.3	-20.8	formate dehydrogenase H subunit alpha selenocysteine-containing
MMP_RS06730		-3.1	-4.3	phosphopantothenate/pantothenate synthetase
MMP_RS00305		-3.0	-3.8	phosphoribosyl-ATP diphosphatase
MMP_RS05515		-2.9	-11.8	cyclic pyranopterin monophosphate synthase MoaC
MMP_RS08720		-2.8	-3.6	4Fe-4S binding protein
MMP_RS06355		-2.8	-6.0	molybdenum cofactor biosynthesis protein MoaE
MMP_RS06345		-2.8	-15.8	formate dehydrogenase accessory sulfurtransferase FdhD
MMP_RS07005		-2.7	-1.4	4Fe-4S binding protein
MMP_RS03315		-2.7	-2.1	ferrous iron transport protein A
MMP_RS03015		-2.7	-12.8	GTP 3' 8-cyclase MoaA
MMP_RS06715		-2.6	-18.4	cache domain-containing protein
MMP_RS07635		-2.6	-10.7	MogA/MoaB family molybdenum cofactor biosynthesis protein
MMP_RS06720		-2.6	-11.1	response regulator transcription factor
MMP_RS02010		-2.5	-12.2	PHP domain-containing protein
MMP_RS06350		-2.5	-11.6	HesA/MoeB/ThiF family protein
MMP_RS08820		-2.5	-7.3	hypothetical protein
MMP_RS01005		-2.3	-3.4	riboflavin synthase
MMP_RS00300		-2.3	-1.5	6 7-dimethyl-8-ribityllumazine synthase
MMP_RS06295		-2.3	-9.2	methanogenesis marker 14 protein
MMP_RS08300		-2.2	-2.5	metal-sulfur cluster assembly factor
MMP_RS06120		-2.2	-4.6	UPF0147 family protein
MMP_RS08460		-2.2	-4.7	proteasome-activating nucleotidase
MMP_RS07445		-2.1	-7.2	helix-turn-helix domain-containing protein
MMP_RS01265		-2.1	-3.6	hypothetical protein
MMP_RS08210		-2.1	-5.2	phosphatidylglycerophosphatase A
MMP_RS07545		-2.1	-2.9	HTH domain-containing protein
MMP_RS01220		-2.1	-10.3	hypothetical protein
MMP_RS04890		-2.1	-1.7	adenylyltransferase/cytidyltransferase family protein
MMP_RS01500		-2.1	-4.1	CBS domain-containing protein
MMP_RS08745		-2.1	-8.7	CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
MMP_RS08635		-2.1	-3.2	UbiA family prenyltransferase
MMP_RS06705		-2.0	-9.7	formate/nitrite transporter family protein
MMP_RS00685		-2.0	-6.3	2-phospho-L-lactate guanylyltransferase
MMP_RS04780		-2.0	-5.2	ribonuclease P
MMP_RS02355		-2.0	-5.0	30S ribosomal protein S27ae
MMP_RS00110		-2.0	-5.3	hypothetical protein
MMP_RS05550		-2.0	-1.7	cation:proton antiporter
MMP_RS02195		-1.9	-6.4	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
MMP_RS06895		-1.9	-2.4	selenocysteine-specific translation elongation factor
MMP_RS00115		-1.9	-13.2	radical SAM protein
MMP_RS00895		-1.9	-4.9	hypothetical protein
MMP_RS04685		-1.8	-6.3	DUF126 domain-containing protein
MMP_RS04775		-1.8	-4.0	adenosylhomocysteinase
MMP_RS06925		-1.8	-3.7	ribonuclease VapC4
MMP_RS05875		-1.7	-6.2	hydroxyethylthiazole kinase
MMP_RS07845		-1.7	-4.1	LL-diaminopimelate aminotransferase
MMP_RS02800		-1.7	-7.8	nucleotidyltransferase domain-containing protein
MMP_RS07575		-1.7	-7.9	RNA ligase partner protein
MMP_RS04585		-1.7	-10.2	AIR synthase related protein
MMP_RS06400		-1.7	-2.5	4Fe-4S binding protein
MMP_RS03445		-1.7	-2.2	methanogenesis marker 17 protein
MMP_RS00295		-1.7	-4.2	gamma carbonic anhydrase family protein
MMP_RS02135		-1.7	-6.0	DUF5612 domain-containing protein
MMP_RS07525		-1.6	-10.3	4Fe-4S binding protein
MMP_RS05920		-1.6	-1.5	50S ribosomal protein L37e
MMP_RS06630		-1.6	-1.7	UPF0058 family protein
MMP_RS01755		-1.6	-1.3	DUF2097 domain-containing protein
MMP_RS03025		-1.6	-6.1	molybdenum cofactor guanylyltransferase
MMP_RS01830		-1.5	-2.9	tRNA-Val
MMP_RS06270		-1.5	-6.3	TIGR00300 family protein
MMP_RS06340		-1.5	-9.4	phosphoadenosine phosphosulfate reductase family protein
MMP_RS01225		-1.5	-6.2	DUF5379 domain-containing protein
MMP_RS03600		-1.5	-2.8	triose-phosphate isomerase
MMP_RS06475		-1.5	-4.3	FAD-dependent oxidoreductase
MMP_RS06625		-1.5	-3.1	DNA primase
MMP_RS07735		-1.5	-2.0	2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
MMP_RS03475		-1.4	-1.1	hypothetical protein
MMP_RS03640		-1.4	-4.1	archaeal proteasome endopeptidase complex subunit beta
MMP_RS05540		-1.4	-4.3	hypothetical protein
MMP_RS02875		-1.4	-8.5	chorismate pyruvate-lyase family protein
MMP_RS06285		-1.4	-3.4	precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
MMP_RS07600		-1.4	-5.2	Ni-sirohydrochlorin a c-diamide synthase
MMP_RS08790		-1.3	-2.3	translation initiation factor IF-2 subunit alpha
MMP_RS03400		-1.3	-3.8	archease
MMP_RS07765		-1.3	-8.3	sodium:alanine symporter family protein
MMP_RS06865		-1.3	-2.4	HypC/HybG/HupF family hydrogenase formation chaperone
MMP_RS03035		-1.3	-4.5	4-hydroxy-tetrahydrodipicolinate synthase
MMP_RS01365		-1.3	-4.4	archaeal proteasome endopeptidase complex subunit alpha
MMP_RS08645		-1.3	-7.4	UPF0179 family protein
MMP_RS01250		-1.3	-6.0	tRNA (guanine(26)-N(2))-dimethyltransferase
MMP_RS02345		-1.2	-3.6	GTP-dependent dephospho-CoA kinase family protein
MMP_RS08435		-1.2	-2.5	Era-like GTP-binding protein
MMP_RS07755		-1.2	-2.2	DUF555 domain-containing protein
MMP_RS07380		-1.2	-3.2	transcription elongation factor Spt5
MMP_RS06020		-1.2	-5.6	archaeoflavoprotein AfpA
MMP_RS00695		-1.2	-1.5	biotin--[acetyl-CoA-carboxylase] ligase
MMP_RS00290		-1.2	-5.2	hypothetical protein
MMP_RS01325		-1.1	-3.3	dihydroneopterin aldolase family protein
MMP_RS05445		-1.1	-6.3	CoB--CoM heterodisulfide reductase subunit B
MMP_RS06885		-1.1	-3.2	50S ribosome-binding GTPase
MMP_RS07555		-1.1	-1.2	monovalent cation/H+ antiporter subunit E
MMP_RS02240		-1.1	-3.9	methanogenesis marker 7 protein
MMP_RS04605		-1.1	-6.6	cobalt ECF transporter T component CbiQ
MMP_RS01800		-1.1	-4.2	TIGR00303 family protein
MMP_RS02165		-1.1	-6.1	tRNA-dihydrouridine synthase
MMP_RS00735		-1.1	-5.2	5 10-methenyltetrahydromethanopterin hydrogenase
MMP_RS01610		-1.1	-3.9	hypothetical protein
MMP_RS05555		-1.1	-2.6	DUF4040 domain-containing protein
MMP_RS09020		-1.1	-1.9	hypothetical protein
MMP_RS08320		-1.1	-6.3	molybdopterin molybdotransferase MoeA
MMP_RS06230		-1.0	-1.6	helix-turn-helix domain-containing protein
MMP_RS07750		-1.0	-3.2	DUF357 domain-containing protein
MMP_RS04615		-1.0	-5.3	PDGLE domain-containing protein
MMP_RS05845		-1.0	-1.9	tRNA-intron lyase
MMP_RS07730		-1.0	-1.8	pyruvate synthase subunit beta
MMP_RS00315		-1.0	-4.6	Nif3-like dinuclear metal center hexameric protein
MMP_RS06105		-1.0	-6.5	hydrogenase maturation peptidase HycI
MMP_RS01980		-1.0	-7.7	trimeric intracellular cation channel family protein
MMP_RS02235		-1.0	-7.6	CBS domain-containing protein
MMP_RS02190		-1.0	-1.6	sulfopyruvate decarboxylase subunit alpha
MMP_RS08165		-0.9	-1.8	phosphoglycerate dehydrogenase
MMP_RS07580		-0.9	-3.8	DUF356 domain-containing protein
MMP_RS02885		-0.9	-8.0	molybdopterin biosynthesis protein
MMP_RS05510		-0.9	-4.3	Rrf2 family transcriptional regulator
MMP_RS01795		-0.9	-2.2	methanogenesis marker 6 protein
MMP_RS08715		-0.9	-1.4	formylmethanofuran dehydrogenase subunit B
MMP_RS08725		-0.9	-2.1	Ni/Fe hydrogenase subunit alpha
MMP_RS07200		-0.9	-4.4	[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
MMP_RS08915		-0.9	-2.0	2 5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase
MMP_RS08330		-0.9	-4.8	NADH-quinone oxidoreductase subunit H
MMP_RS04850		-0.9	-7.3	UPF0254 family protein
MMP_RS08200		-0.8	-7.3	archaeosine synthase subunit alpha
MMP_RS04620		-0.8	-6.1	cobalt transporter CbiM
MMP_RS07700		-0.8	-5.4	DUF1188 domain-containing protein
MMP_RS05545		-0.8	-4.2	pyridoxal phosphate-dependent aminotransferase
MMP_RS03095		-0.8	-6.2	diphthine synthase
MMP_RS07630		-0.8	-2.0	ATP-binding cassette domain-containing protein
MMP_RS06175		-0.8	-5.0	winged helix-turn-helix transcriptional regulator
MMP_RS03555		-0.8	-3.9	transcriptional regulator
MMP_RS02245		-0.8	-3.1	hypothetical protein
MMP_RS01700		-0.8	-1.0	dihydroxy-acid dehydratase
MMP_RS06485		-0.8	-1.3	zinc ribbon domain-containing protein
MMP_RS05245		-0.8	-5.7	archaeosine biosynthesis radical SAM protein RaSEA
MMP_RS05090		-0.8	-5.0	CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
MMP_RS05765		-0.8	-4.3	M42 family metallopeptidase
MMP_RS01385		-0.8	-0.8	imidazole glycerol phosphate synthase subunit HisH
MMP_RS01725		-0.8	-2.4	class I SAM-dependent methyltransferase family protein
MMP_RS07425		-0.7	-4.1	GTP-binding protein
MMP_RS05815		-0.7	-2.2	NOL1/NOP2/sun family putative RNA methylase
MMP_RS06200		-0.7	-5.4	M24 family metallopeptidase
MMP_RS05345		-0.7	-3.7	hypothetical protein
MMP_RS03580		-0.7	-3.4	signal recognition particle-docking protein FtsY
MMP_RS05315		-0.7	-2.3	hypothetical protein
MMP_RS05430		-0.7	-3.0	TIGR00288 family NYN domain-containing protein
MMP_RS00620		-0.7	-4.3	4Fe-4S binding protein
MMP_RS03960		-0.7	-0.9	hypothetical protein
MMP_RS07605		-0.7	-1.8	diadenylate cyclase
MMP_RS05060		-0.7	-5.7	AAA family ATPase
MMP_RS04870		-0.7	-2.3	TIGR02253 family HAD-type hydrolase
MMP_RS09055		-0.7	-1.2	CAP domain-containing protein
MMP_RS05425		-0.7	-3.2	monovalent cation/H+ antiporter complex subunit F
MMP_RS03155		-0.7	-3.5	precorrin-6A reductase
MMP_RS00730		-0.7	-3.5	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
MMP_RS06930		-0.7	-5.3	MBL fold metallo-hydrolase
MMP_RS07695		-0.7	-4.1	DUF3236 domain-containing protein
MMP_RS04500		-0.7	-5.6	adenosylmethionine--8-amino-7-oxononanoate transaminase
MMP_RS05450		-0.7	-4.1	CoB--CoM heterodisulfide reductase subunit C
MMP_RS07535		-0.7	-4.5	4Fe-4S binding protein
MMP_RS07685		-0.7	-4.4	TIGR01212 family radical SAM protein
MMP_RS04875		-0.7	-2.5	energy-converting hydrogenase B subunit P
MMP_RS07365		-0.7	-5.0	2-phosphoglycerate kinase
MMP_RS02145		-0.7	-3.0	winged helix-turn-helix transcriptional regulator
MMP_RS06525		-0.7	-1.5	YciI family protein
MMP_RS00515		-0.7	-0.6	DUF655 domain-containing protein
MMP_RS01985		-0.6	-2.8	F420-dependent methylenetetrahydromethanopterin dehydrogenase
MMP_RS02175		-0.6	-0.9	DUF1611 domain-containing protein
MMP_RS07625		-0.6	-3.3	cobalt ECF transporter T component CbiQ
MMP_RS00050		-0.6	-3.2	AarF/UbiB family protein
MMP_RS00810		-0.6	-3.8	topoisomerase DNA-binding C4 zinc finger domain-containing protein
MMP_RS08650		-0.6	-1.4	glutamine--fructose-6-phosphate transaminase (isomerizing)
MMP_RS01600		-0.6	-1.4	50S ribosomal protein L15e
MMP_RS05925		-0.6	-1.7	small nuclear ribonucleoprotein
MMP_RS05100		-0.6	-5.2	CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
MMP_RS00120		-0.6	-3.5	LysR family transcriptional regulator
MMP_RS07775		-0.6	-3.8	alanine dehydrogenase
MMP_RS05070		-0.6	-3.3	4Fe-4S dicluster domain-containing protein
MMP_RS05440		-0.6	-3.8	winged helix-turn-helix transcriptional regulator
MMP_RS05080		-0.6	-4.7	acetyl-CoA decarbonylase/synthase complex subunit delta
MMP_RS00060		-0.6	-1.0	3-dehydroquinate synthase II
MMP_RS08445		-0.6	-2.5	DUF2099 family protein
MMP_RS01335		-0.6	-2.1	prefoldin subunit beta
MMP_RS01030		-0.6	-1.8	MTAP family purine nucleoside phosphorylase
MMP_RS05265		-0.5	-1.3	2-isopropylmalate synthase
MMP_RS03305		-0.5	-3.9	winged helix-turn-helix domain-containing protein
MMP_RS07790		-0.5	-4.3	segregation/condensation protein A
MMP_RS00320		-0.5	-1.5	class I SAM-dependent methyltransferase
MMP_RS03435		-0.5	-1.2	ketol-acid reductoisomerase
MMP_RS06315		-0.5	-0.9	cobalt-precorrin-7 (C(5))-methyltransferase
MMP_RS08070		-0.5	-2.9	DUF2096 domain-containing protein
MMP_RS05095		-0.5	-4.2	CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
MMP_RS06395		-0.5	-2.4	ThiF family adenylyltransferase
MMP_RS03385		-0.5	-1.0	cation diffusion facilitator family transporter
MMP_RS08105		-0.5	-3.1	6-carboxyhexanoate--CoA ligase
MMP_RS02130		-0.5	-1.8	zinc metalloprotease HtpX
MMP_RS00725		-0.5	-2.2	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments