Experiment set5IT039 for Methanococcus maripaludis S2

200 most detrimental genes:

gene	name	fitness	t score	description
MMP_RS07820		+1.1	5.3	UPF0104 family protein
MMP_RS01370		+0.8	6.6	acetate--CoA ligase family protein
MMP_RS07875		+0.7	3.6	hypothetical protein
MMP_RS01960		+0.7	0.6	hypothetical protein
MMP_RS01540		+0.7	3.4	DUF504 domain-containing protein
MMP_RS01545		+0.6	1.1	CBS domain-containing protein
MMP_RS00450		+0.5	0.9	4Fe-4S binding protein
MMP_RS07860		+0.5	0.8	hypothetical protein
MMP_RS07330		+0.5	4.6	membrane protein
MMP_RS06555		+0.5	2.4	cupin domain-containing protein
MMP_RS07115		+0.5	4.2	MBL fold metallo-hydrolase
MMP_RS01775		+0.5	1.6	TIGR00297 family protein
MMP_RS07345		+0.5	3.1	glycine synthesis protein GlyXL (from data)
MMP_RS07125		+0.5	3.2	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS06290		+0.5	2.6	DNA repair and recombination protein RadA
MMP_RS06545		+0.4	3.3	ferredoxin family protein
MMP_RS07130		+0.4	3.1	coenzyme F420 hydrogenase subunit gamma
MMP_RS07120		+0.4	3.6	coenzyme F420 hydrogenase subunit alpha
MMP_RS01525		+0.4	1.6	nucleoside-diphosphate kinase
MMP_RS05535		+0.4	1.9	hypothetical protein
MMP_RS00520		+0.4	0.9	RNA polymerase Rpb4 family protein
MMP_RS06155		+0.4	1.0	DUF4186 domain-containing protein
MMP_RS05580		+0.4	3.6	glycosyltransferase
MMP_RS00530		+0.4	3.1	tRNA pseudouridine(54/55) synthase Pus10
MMP_RS07095		+0.4	1.0	PspC domain-containing protein
MMP_RS04520		+0.4	2.0	nucleoside deaminase
MMP_RS00740		+0.4	1.3	cyclase family protein
MMP_RS02475		+0.4	1.8	hypothetical protein
MMP_RS03215		+0.4	2.8	MBL fold metallo-hydrolase
MMP_RS02310		+0.4	1.3	RimK-like ATPgrasp N-terminal domain-containing protein
MMP_RS09025		+0.4	0.9	hypothetical protein
MMP_RS06435		+0.4	2.4	CBS domain-containing protein
MMP_RS03535		+0.4	1.8	helix-turn-helix transcriptional regulator
MMP_RS08155		+0.4	2.1	hypothetical protein
MMP_RS06540		+0.4	1.6	3-methyl-2-oxobutanoate dehydrogenase subunit VorB
MMP_RS07135		+0.3	2.7	coenzyme F420 hydrogenase subunit beta
MMP_RS06600		+0.3	0.8	class III signal peptide-containing protein
MMP_RS00945		+0.3	0.8	PadR family transcriptional regulator
MMP_RS00825		+0.3	1.5	fumarylacetoacetate hydrolase family protein
MMP_RS00395		+0.3	1.2	MGMT family protein
MMP_RS08275		+0.3	2.9	hypothetical protein
MMP_RS05635		+0.3	2.0	NAD-dependent epimerase/dehydratase family protein
MMP_RS06535		+0.3	1.5	2-oxoacid:acceptor oxidoreductase family protein
MMP_RS05640		+0.3	1.9	UTP--glucose-1-phosphate uridylyltransferase GalU
MMP_RS08315		+0.3	1.2	S-methyl-5-thioribose-1-phosphate isomerase
MMP_RS03245		+0.3	2.2	DNA repair and recombination protein RadB
MMP_RS04985		+0.3	1.2	DUF2180 family protein
MMP_RS08455		+0.3	2.0	multiprotein bridging factor aMBF1
MMP_RS06530		+0.3	1.8	bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
MMP_RS08705		+0.3	2.4	sulfopyruvate decarboxylase subunit beta
MMP_RS07925		+0.3	1.6	haloacid dehalogenase
MMP_RS01165		+0.3	1.8	DUF434 domain-containing protein
MMP_RS00565		+0.3	1.3	CBS domain-containing protein
MMP_RS02085		+0.3	2.0	inosine/xanthosine triphosphatase
MMP_RS08415		+0.3	1.2	radical SAM protein
MMP_RS01940		+0.3	1.5	MoxR family ATPase
MMP_RS03910		+0.3	0.7	hypothetical protein
MMP_RS01110		+0.3	1.5	FmdE family protein
MMP_RS02805		+0.3	0.8	HEPN domain-containing protein
MMP_RS00145		+0.3	1.8	ATP-dependent Clp protease proteolytic subunit
MMP_RS01650		+0.3	0.7	sulfurtransferase TusA family protein
MMP_RS01185		+0.3	1.6	hypothetical protein
MMP_RS06570		+0.3	0.9	DUF190 domain-containing protein
MMP_RS07410		+0.3	2.2	4-demethylwyosine synthase TYW1
MMP_RS02495		+0.3	1.3	hypothetical protein
MMP_RS08995		+0.3	0.8	hypothetical protein
MMP_RS06550		+0.3	2.0	AMP-binding protein
MMP_RS01270		+0.3	2.5	prepilin peptidase
MMP_RS02290		+0.3	1.8	MBL fold metallo-hydrolase
MMP_RS07890		+0.3	0.6	OB-fold nucleic acid binding domain-containing protein
MMP_RS00325		+0.3	0.5	RNA-binding protein
MMP_RS08855		+0.3	1.9	hypothetical protein
MMP_RS03450		+0.3	0.7	glycine synthesis protein GlyXS (from data)
MMP_RS02360		+0.3	1.5	hypothetical protein
MMP_RS07895		+0.3	1.7	cytochrome c
MMP_RS02455		+0.2	1.8	hypothetical protein
MMP_RS03340		+0.2	0.4	ABC transporter ATP-binding protein
MMP_RS00660		+0.2	1.9	alkaline phosphatase family protein
MMP_RS06325		+0.2	0.7	hypothetical protein
MMP_RS03440		+0.2	0.6	MoaD/ThiS family protein
MMP_RS00535		+0.2	1.3	TIGR00375 family protein
MMP_RS03065		+0.2	1.0	AzlC family ABC transporter permease
MMP_RS02725		+0.2	1.7	molybdate ABC transporter permease subunit
MMP_RS08400		+0.2	1.5	MJ0307 family thioredoxin
MMP_RS04035		+0.2	0.9	hypothetical protein
MMP_RS07435		+0.2	0.7	GMP synthase subunit A
MMP_RS01580		+0.2	1.4	PQQ-binding-like beta-propeller repeat protein
MMP_RS03520		+0.2	1.0	YwbE family protein
MMP_RS06610		+0.2	1.5	DUF2334 domain-containing protein
MMP_RS07855		+0.2	1.6	class I SAM-dependent methyltransferase
MMP_RS08660		+0.2	1.2	DHH family phosphoesterase
MMP_RS09035		+0.2	1.0	hypothetical protein
MMP_RS02915		+0.2	1.0	amino acid ABC transporter permease
MMP_RS06575		+0.2	1.2	fluoride efflux transporter CrcB
MMP_RS09050		+0.2	1.4	CAP domain-containing protein
MMP_RS05715		+0.2	1.2	hypothetical protein
MMP_RS08605		+0.2	1.2	flagellar protein E
MMP_RS05180		+0.2	1.8	Nre family DNA repair protein
MMP_RS02110		+0.2	0.7	hypothetical protein
MMP_RS01570		+0.2	0.7	hypothetical protein
MMP_RS07835		+0.2	1.0	TldD/PmbA family protein
MMP_RS02770		+0.2	0.8	hypothetical protein
MMP_RS02480		+0.2	0.9	hypothetical protein
MMP_RS01130		+0.2	1.8	flavoprotein
MMP_RS05940		+0.2	1.4	corrinoid protein
MMP_RS01655		+0.2	1.0	DsrE family protein
MMP_RS00545		+0.2	1.3	XRE family transcriptional regulator
MMP_RS05660		+0.2	1.4	phosphate ABC transporter substrate-binding protein
MMP_RS01930		+0.2	1.6	hypothetical protein
MMP_RS03890		+0.2	1.4	DUF2540 domain-containing protein
MMP_RS03320		+0.2	0.8	metal-dependent transcriptional regulator
MMP_RS08860		+0.2	1.0	MinD/ParA family protein
MMP_RS04480		+0.2	1.9	lysine 2 3-aminomutase
MMP_RS04105		+0.2	1.0	MarR family transcriptional regulator
MMP_RS01415		+0.2	1.1	DUF2067 domain-containing protein
MMP_RS02720		+0.2	0.6	molybdate ABC transporter substrate-binding protein
MMP_RS01140		+0.2	1.1	molybdate ABC transporter permease subunit
MMP_RS03765		+0.2	1.0	CopG family ribbon-helix-helix protein
MMP_RS08890		+0.2	1.6	glycosyltransferase family 4 protein
MMP_RS08590		+0.2	1.3	flagellin
MMP_RS02790		+0.2	0.4	class III signal peptide-containing protein
MMP_RS06140		+0.2	0.6	radical SAM protein
MMP_RS07090		+0.2	1.2	tRNA (adenine-N1)-methyltransferase
MMP_RS02045		+0.2	0.6	tRNA-Met
MMP_RS04715		+0.2	1.1	CBS domain-containing protein
MMP_RS07355		+0.2	0.4	transcription factor S
MMP_RS06185		+0.2	1.2	thermonuclease family protein
MMP_RS00940		+0.2	1.5	daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein
MMP_RS08470		+0.2	1.5	ATP-binding cassette domain-containing protein
MMP_RS01310		+0.2	1.6	hypothetical protein
MMP_RS05295		+0.2	1.4	minichromosome maintenance protein MCM
MMP_RS01470		+0.2	1.0	ATP-binding cassette domain-containing protein
MMP_RS01945		+0.2	1.1	DUF4350 domain-containing protein
MMP_RS05985		+0.2	1.0	hypothetical protein
MMP_RS04790		+0.2	1.2	4-hydroxy-tetrahydrodipicolinate reductase
MMP_RS04055		+0.2	0.6	hypothetical protein
MMP_RS02255		+0.2	1.2	hypothetical protein
MMP_RS08215		+0.2	0.9	DUF483 domain-containing protein
MMP_RS01950		+0.2	1.3	hypothetical protein
MMP_RS08555		+0.2	0.7	hypothetical protein
MMP_RS08595		+0.2	0.3	flagellar protein C
MMP_RS01010		+0.2	1.4	DUF4352 domain-containing protein
MMP_RS00240		+0.2	1.5	type II secretion system F family protein
MMP_RS03130		+0.2	1.2	hypothetical protein
MMP_RS06745		+0.2	1.1	DUF2119 domain-containing protein
MMP_RS02225		+0.2	1.4	carbohydrate kinase family protein
MMP_RS06165		+0.2	1.0	ABC transporter permease
MMP_RS00635		+0.2	1.3	energy-coupling factor transporter transmembrane protein EcfT
MMP_RS00055		+0.2	1.3	DUF2254 domain-containing protein
MMP_RS06480		+0.2	1.0	ABC transporter substrate-binding protein
MMP_RS08760		+0.2	0.7	hypothetical protein
MMP_RS08945		+0.2	1.3	hypothetical protein
MMP_RS01435		+0.2	1.0	DMT family transporter
MMP_RS07155		+0.2	1.3	MFS transporter
MMP_RS08775		+0.2	1.1	methanogenesis marker 9 domain-containing protein
MMP_RS00850		+0.2	0.8	TIGR01177 family methyltransferase
MMP_RS06900		+0.2	0.6	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS02960		+0.2	1.1	class I SAM-dependent methyltransferase family protein
MMP_RS01865		+0.2	0.5	GPR1/FUN34/YaaH family transporter
MMP_RS05235		+0.2	1.2	exodeoxyribonuclease III
MMP_RS00930		+0.2	0.9	ABC transporter permease
MMP_RS07915		+0.2	0.7	DUF4870 domain-containing protein
MMP_RS02365		+0.2	1.0	nitrogen fixation
MMP_RS07185		+0.2	1.1	pyridoxal phosphate-dependent aminotransferase
MMP_RS02315		+0.1	1.0	RimK family alpha-L-glutamate ligase
MMP_RS08475		+0.1	1.2	ABC transporter permease
MMP_RS06170		+0.1	1.2	ABC transporter ATP-binding protein
MMP_RS02545		+0.1	1.2	hypothetical protein
MMP_RS05980		+0.1	0.8	ferritin
MMP_RS06375		+0.1	1.0	ATP-dependent sacrificial sulfur transferase LarE
MMP_RS06460		+0.1	0.8	pyrimidine dimer DNA glycosylase/endonuclease V
MMP_RS06495		+0.1	0.4	YkgJ family cysteine cluster protein
MMP_RS06300		+0.1	1.2	ABC transporter substrate-binding protein
MMP_RS07725		+0.1	0.8	4Fe-4S dicluster domain-containing protein
MMP_RS06665		+0.1	1.1	glycogen/starch synthase
MMP_RS02970		+0.1	1.1	hypothetical protein
MMP_RS07850		+0.1	0.5	prephenate dehydratase
MMP_RS03790		+0.1	1.1	hypothetical protein
MMP_RS02260		+0.1	1.1	lactate utilization protein
MMP_RS03405		+0.1	1.0	RNA 3'-terminal phosphate cyclase
MMP_RS04740		+0.1	0.8	DUF473 domain-containing protein
MMP_RS01145		+0.1	1.1	ABC transporter ATP-binding protein
MMP_RS06970		+0.1	0.9	ribosomal protein S18-alanine N-acetyltransferase
MMP_RS05960		+0.1	1.2	CoB--CoM heterodisulfide reductase subunit B
MMP_RS06000		+0.1	0.8	divalent-cation tolerance protein CutA
MMP_RS06905		+0.1	0.6	hypothetical protein
MMP_RS01465		+0.1	0.6	hypothetical protein
MMP_RS04145		+0.1	0.5	hypothetical protein
MMP_RS06085		+0.1	1.2	iron ABC transporter substrate-binding protein
MMP_RS00085		+0.1	1.0	DNA cytosine methyltransferase
MMP_RS08580		+0.1	0.5	flagellin
MMP_RS03740		+0.1	0.8	indolepyruvate oxidoreductase subunit beta
MMP_RS01420		+0.1	0.5	hypothetical protein
MMP_RS04265		+0.1	0.5	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS05665		+0.1	0.7	phosphate ABC transporter permease subunit PstC
MMP_RS01300		+0.1	1.1	hypothetical protein
MMP_RS01315		+0.1	1.2	DUF2341 domain-containing protein
MMP_RS06910		+0.1	0.9	RlmF-related methyltransferase
MMP_RS03150		+0.1	1.0	phosphoglycerate mutase
MMP_RS01285		+0.1	1.1	hypothetical protein

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments