Experiment set5IT036 for Methanococcus maripaludis S2

Compare to:

H2 deepwell autotrophic conditions

200 most important genes:

  gene name fitness t score description  
MMP_RS05500 -8.8 -7.1 2-isopropylmalate synthase compare
MMP_RS04605 -8.7 -3.8 cobalt ECF transporter T component CbiQ compare
MMP_RS07845 -8.7 -2.2 LL-diaminopimelate aminotransferase compare
MMP_RS03450 -8.5 -2.2 glycine synthesis protein GlyXS (from data) compare
MMP_RS06270 -7.1 -4.9 TIGR00300 family protein compare
MMP_RS07345 -6.5 -5.8 glycine synthesis protein GlyXL (from data) compare
MMP_RS06120 -6.4 -1.9 UPF0147 family protein compare
MMP_RS09020 -6.4 -1.6 hypothetical protein compare
MMP_RS06625 -6.3 -1.8 DNA primase compare
MMP_RS01020 -6.2 -0.9 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS07630 -6.1 -1.6 ATP-binding cassette domain-containing protein compare
MMP_RS04215 -6.1 -7.9 nickel pincer cofactor biosynthesis protein LarB compare
MMP_RS03435 -6.0 -1.7 ketol-acid reductoisomerase compare
MMP_RS02280 -5.9 -0.9 DUF211 domain-containing protein compare
MMP_RS04620 -5.8 -12.0 cobalt transporter CbiM compare
MMP_RS04615 -5.8 -3.8 PDGLE domain-containing protein compare
MMP_RS08440 -5.8 -2.6 cell division protein SepF compare
MMP_RS08650 -5.7 -2.5 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS07730 -5.7 -1.9 pyruvate synthase subunit beta compare
MMP_RS05060 -5.6 -10.3 AAA family ATPase compare
MMP_RS01175 -5.5 -3.6 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS01455 -5.5 -5.3 nickel pincer cofactor biosynthesis protein LarC compare
MMP_RS05555 -5.4 -1.1 DUF4040 domain-containing protein compare
MMP_RS05085 -5.4 -9.8 AAA family ATPase compare
MMP_RS05070 -5.3 -8.7 4Fe-4S dicluster domain-containing protein compare
MMP_RS06925 -5.3 -2.4 ribonuclease VapC4 compare
MMP_RS08745 -5.3 -7.6 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS06400 -5.3 -1.8 4Fe-4S binding protein compare
MMP_RS03315 -5.2 -1.3 ferrous iron transport protein A compare
MMP_RS05080 -5.1 -11.6 acetyl-CoA decarbonylase/synthase complex subunit delta compare
MMP_RS06975 -5.0 -2.1 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS05095 -5.0 -5.4 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS08720 -5.0 -1.5 4Fe-4S binding protein compare
MMP_RS05100 -4.9 -20.5 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMP_RS06375 -4.9 -3.7 ATP-dependent sacrificial sulfur transferase LarE compare
MMP_RS01755 -4.8 -1.0 DUF2097 domain-containing protein compare
MMP_RS05075 -4.8 -15.9 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMP_RS04500 -4.8 -16.3 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS03700 -4.7 -10.7 sodium:proton antiporter compare
MMP_RS05925 -4.7 -3.9 small nuclear ribonucleoprotein compare
MMP_RS04685 -4.7 -3.3 DUF126 domain-containing protein compare
MMP_RS01830 -4.6 -1.4 tRNA-Val compare
MMP_RS01955 -4.6 -3.1 hypothetical protein compare
MMP_RS05090 -4.6 -8.3 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS01385 -4.6 -0.7 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS00300 -4.6 -0.7 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS06370 -4.6 -4.8 biotin synthase BioB compare
MMP_RS03035 -4.6 -4.0 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS01795 -4.5 -1.8 methanogenesis marker 6 protein compare
MMP_RS07545 -4.5 -0.9 HTH domain-containing protein compare
MMP_RS05055 -4.5 -14.2 DUF166 domain-containing protein compare
MMP_RS03015 -4.5 -9.8 GTP 3' 8-cyclase MoaA compare
MMP_RS06355 -4.4 -2.6 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS02240 -4.4 -3.1 methanogenesis marker 7 protein compare
MMP_RS06230 -4.3 -2.3 helix-turn-helix domain-containing protein compare
MMP_RS06730 -4.3 -2.1 phosphopantothenate/pantothenate synthetase compare
MMP_RS01500 -4.3 -2.1 CBS domain-containing protein compare
MMP_RS01005 -4.2 -1.2 riboflavin synthase compare
MMP_RS00305 -4.2 -1.9 phosphoribosyl-ATP diphosphatase compare
MMP_RS02900 -4.2 -0.6 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS05515 -4.2 -7.0 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS08095 -4.2 -6.3 dethiobiotin synthase compare
MMP_RS05065 -4.1 -5.2 CooT family nickel-binding protein compare
MMP_RS04780 -4.1 -3.5 ribonuclease P compare
MMP_RS05930 -4.1 -2.5 3-isopropylmalate dehydratase large subunit compare
MMP_RS07185 -4.1 -10.0 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS08105 -4.1 -7.9 6-carboxyhexanoate--CoA ligase compare
MMP_RS04710 -4.1 -1.6 hypothetical protein compare
MMP_RS01610 -4.0 -3.3 hypothetical protein compare
MMP_RS02195 -4.0 -3.8 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS03640 -4.0 -3.8 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS05425 -4.0 -5.1 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS03580 -4.0 -3.9 signal recognition particle-docking protein FtsY compare
MMP_RS02135 -4.0 -4.8 DUF5612 domain-containing protein compare
MMP_RS06315 -3.9 -0.8 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS08100 -3.9 -6.5 8-amino-7-oxononanoate synthase compare
MMP_RS03960 -3.9 -0.8 hypothetical protein compare
MMP_RS01265 -3.9 -2.7 hypothetical protein compare
MMP_RS06295 -3.9 -7.6 methanogenesis marker 14 protein compare
MMP_RS01700 -3.8 -0.8 dihydroxy-acid dehydratase compare
MMP_RS07735 -3.8 -0.8 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS06350 -3.8 -7.7 HesA/MoeB/ThiF family protein compare
MMP_RS05640 -3.8 -7.7 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS02145 -3.7 -6.9 winged helix-turn-helix transcriptional regulator compare
MMP_RS03025 -3.7 -5.9 molybdenum cofactor guanylyltransferase compare
MMP_RS01925 -3.7 -11.2 DUF1616 domain-containing protein compare
MMP_RS08790 -3.7 -1.7 translation initiation factor IF-2 subunit alpha compare
MMP_RS01800 -3.6 -4.2 TIGR00303 family protein compare
MMP_RS07555 -3.6 -0.7 monovalent cation/H+ antiporter subunit E compare
MMP_RS06340 -3.6 -7.8 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS02345 -3.6 -3.6 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS05845 -3.6 -1.8 tRNA-intron lyase compare
MMP_RS08715 -3.5 -1.8 formylmethanofuran dehydrogenase subunit B compare
MMP_RS07635 -3.5 -5.9 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS07600 -3.5 -2.4 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS04890 -3.4 -0.7 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS01380 -3.4 -4.3 PHP domain-containing protein compare
MMP_RS01900 -3.4 -14.5 hypothetical protein compare
MMP_RS06895 -3.4 -1.7 selenocysteine-specific translation elongation factor compare
MMP_RS07195 -3.4 -10.7 M20 family metallo-hydrolase compare
MMP_RS07645 -3.4 -5.2 aldehyde dehydrogenase family protein compare
MMP_RS01905 -3.4 -15.3 glycosyltransferase compare
MMP_RS01545 -3.3 -0.8 CBS domain-containing protein compare
MMP_RS05265 -3.3 -2.7 2-isopropylmalate synthase compare
MMP_RS08330 -3.3 -3.8 NADH-quinone oxidoreductase subunit H compare
MMP_RS02010 -3.2 -8.3 PHP domain-containing protein compare
MMP_RS06285 -3.2 -2.3 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS07575 -3.2 -3.4 RNA ligase partner protein compare
MMP_RS04790 -3.2 -12.9 4-hydroxy-tetrahydrodipicolinate reductase compare
MMP_RS01910 -3.1 -9.7 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS01960 -3.1 -0.6 hypothetical protein compare
MMP_RS08210 -3.1 -2.3 phosphatidylglycerophosphatase A compare
MMP_RS07955 -3.1 -4.8 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS00695 -3.1 -0.9 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS06630 -3.1 -0.9 UPF0058 family protein compare
MMP_RS03390 -3.0 -8.3 malate dehydrogenase compare
MMP_RS03600 -3.0 -2.2 triose-phosphate isomerase compare
MMP_RS07200 -3.0 -7.6 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS06475 -3.0 -4.4 FAD-dependent oxidoreductase compare
MMP_RS02875 -3.0 -10.5 chorismate pyruvate-lyase family protein compare
MMP_RS07380 -3.0 -2.0 transcription elongation factor Spt5 compare
MMP_RS03140 -2.9 -10.6 hypothetical protein compare
MMP_RS00750 -2.9 -2.4 fumarate hydratase compare
MMP_RS01915 -2.9 -15.8 DUF354 domain-containing protein compare
MMP_RS08165 -2.9 -2.1 phosphoglycerate dehydrogenase compare
MMP_RS07625 -2.9 -3.7 cobalt ECF transporter T component CbiQ compare
MMP_RS03145 -2.9 -6.8 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS08240 -2.9 -6.6 methanogenesis marker 16 metalloprotein compare
MMP_RS06105 -2.8 -8.1 hydrogenase maturation peptidase HycI compare
MMP_RS02355 -2.8 -3.0 30S ribosomal protein S27ae compare
MMP_RS07075 -2.8 -4.6 phosphomannomutase/phosphoglucomutase compare
MMP_RS06930 -2.8 -10.5 MBL fold metallo-hydrolase compare
MMP_RS00515 -2.8 -1.0 DUF655 domain-containing protein compare
MMP_RS07755 -2.8 -1.1 DUF555 domain-containing protein compare
MMP_RS00895 -2.8 -3.1 hypothetical protein compare
MMP_RS07750 -2.7 -5.1 DUF357 domain-containing protein compare
MMP_RS07365 -2.7 -8.8 2-phosphoglycerate kinase compare
MMP_RS07875 -2.7 -4.4 hypothetical protein compare
MMP_RS06310 -2.7 -5.3 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS01225 -2.7 -4.4 DUF5379 domain-containing protein compare
MMP_RS05550 -2.7 -0.8 cation:proton antiporter compare
MMP_RS08320 -2.6 -5.6 molybdopterin molybdotransferase MoeA compare
MMP_RS03445 -2.6 -1.1 methanogenesis marker 17 protein compare
MMP_RS08635 -2.5 -1.9 UbiA family prenyltransferase compare
MMP_RS00685 -2.5 -2.8 2-phospho-L-lactate guanylyltransferase compare
MMP_RS08820 -2.5 -4.4 hypothetical protein compare
MMP_RS04775 -2.5 -3.4 adenosylhomocysteinase compare
MMP_RS07525 -2.5 -7.7 4Fe-4S binding protein compare
MMP_RS01875 -2.5 -9.1 N-acetyltransferase compare
MMP_RS07615 -2.4 -7.1 energy-coupling factor ABC transporter permease compare
MMP_RS05815 -2.4 -1.9 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS08300 -2.4 -1.0 metal-sulfur cluster assembly factor compare
MMP_RS03420 -2.4 -2.7 acetolactate synthase small subunit compare
MMP_RS01970 -2.4 -12.4 TIGR04279 domain-containing protein compare
MMP_RS01885 -2.4 -7.9 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS04720 -2.3 -3.0 DedA family protein compare
MMP_RS08335 -2.3 -5.8 NADH-quinone oxidoreductase subunit B family protein compare
MMP_RS08760 -2.3 -1.8 hypothetical protein compare
MMP_RS08460 -2.3 -2.1 proteasome-activating nucleotidase compare
MMP_RS01895 -2.3 -10.4 flippase compare
MMP_RS00985 -2.2 -4.4 CDC48 family AAA ATPase compare
MMP_RS07720 -2.2 -14.4 4Fe-4S binding protein compare
MMP_RS01920 -2.2 -12.6 glycosyltransferase family 2 protein compare
MMP_RS08355 -2.2 -4.8 Na(+)/H(+) antiporter subunit B compare
MMP_RS02885 -2.2 -13.4 molybdopterin biosynthesis protein compare
MMP_RS00110 -2.2 -2.4 hypothetical protein compare
MMP_RS06885 -2.2 -2.1 50S ribosome-binding GTPase compare
MMP_RS00520 -2.1 -1.6 RNA polymerase Rpb4 family protein compare
MMP_RS08340 -2.1 -3.3 4Fe-4S binding protein compare
MMP_RS05950 -2.1 -7.6 nickel-dependent hydrogenase large subunit compare
MMP_RS05540 -2.1 -3.2 hypothetical protein compare
MMP_RS06020 -2.1 -3.8 archaeoflavoprotein AfpA compare
MMP_RS01890 -2.1 -3.6 nucleotide sugar dehydrogenase compare
MMP_RS02800 -2.1 -5.1 nucleotidyltransferase domain-containing protein compare
MMP_RS06700 -2.1 -8.5 hypothetical protein compare
MMP_RS01325 -2.1 -1.9 dihydroneopterin aldolase family protein compare
MMP_RS03155 -2.1 -6.3 precorrin-6A reductase compare
MMP_RS08645 -2.1 -5.7 UPF0179 family protein compare
MMP_RS07005 -2.1 -0.5 4Fe-4S binding protein compare
MMP_RS01220 -2.0 -4.9 hypothetical protein compare
MMP_RS01975 -2.0 -11.5 hypothetical protein compare
MMP_RS01880 -2.0 -5.8 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS02245 -2.0 -2.9 hypothetical protein compare
MMP_RS07445 -1.9 -3.6 helix-turn-helix domain-containing protein compare
MMP_RS03475 -1.9 -0.5 hypothetical protein compare
MMP_RS08345 -1.9 -9.8 4Fe-4S binding protein compare
MMP_RS01720 -1.9 -1.9 replication factor C large subunit compare
MMP_RS05920 -1.9 -0.6 50S ribosomal protein L37e compare
MMP_RS06130 -1.8 -3.3 peptidylprolyl isomerase compare
MMP_RS07390 -1.8 -1.8 cell division protein FtsZ compare
MMP_RS00050 -1.8 -6.4 AarF/UbiB family protein compare
MMP_RS06290 -1.8 -3.2 DNA repair and recombination protein RadA compare
MMP_RS08350 -1.8 -0.8 hypothetical protein compare
MMP_RS07710 -1.8 -4.9 cell division protein FtsZ compare
MMP_RS07580 -1.8 -2.2 DUF356 domain-containing protein compare
MMP_RS03095 -1.8 -5.1 diphthine synthase compare
MMP_RS03400 -1.8 -1.4 archease compare
MMP_RS00735 -1.7 -3.4 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS08365 -1.7 -3.6 energy conserving hydrogenase EhbF compare
MMP_RS01725 -1.7 -3.5 class I SAM-dependent methyltransferase family protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t2 experiments