Experiment set5IT035 for Klebsiella michiganensis M5al

Compare to:

D-Raffinose pentahydrate carbon source

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS08625 +7.4 25.5 UDP-glucose 4-epimerase GalE compare
BWI76_RS20090 +5.1 30.2 ribonuclease Z compare
BWI76_RS08615 +5.0 40.2 galactokinase compare
BWI76_RS08620 +4.5 15.7 galactose-1-phosphate uridylyltransferase compare
BWI76_RS01185 +3.2 9.4 adenylate cyclase compare
BWI76_RS19105 +2.7 12.1 GalU regulator GalF compare
BWI76_RS07845 +2.6 11.7 LacI family transcriptional regulator compare
BWI76_RS00940 +2.6 12.7 transcriptional regulator HdfR compare
BWI76_RS24575 +2.5 3.7 hypothetical protein compare
BWI76_RS26620 +2.0 3.7 Fe-S biogenesis protein NfuA compare
BWI76_RS11430 +2.0 2.9 lipoprotein compare
BWI76_RS08610 +2.0 4.8 galactose-1-epimerase compare
BWI76_RS06205 +1.6 3.1 recombination-associated protein RdgC compare
BWI76_RS21245 +1.5 2.4 nitrogen regulatory protein P-II compare
BWI76_RS19490 +1.5 1.7 binding-protein-dependent transport system inner membrane protein compare
BWI76_RS18755 +1.5 2.4 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS15150 +1.3 3.7 outer membrane efflux protein compare
BWI76_RS19575 +1.3 1.0 maleylacetoacetate isomerase compare
BWI76_RS12040 +1.3 2.0 hypothetical protein compare
BWI76_RS18165 +1.3 2.2 NUDIX pyrophosphatase compare
BWI76_RS12200 +1.3 3.1 hypothetical protein compare
BWI76_RS16195 +1.3 1.4 hypothetical protein compare
BWI76_RS27670 +1.2 2.7 LysR family transcriptional regulator compare
BWI76_RS09910 +1.2 10.3 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS12790 +1.2 2.1 lactate dehydrogenase compare
BWI76_RS22975 +1.2 4.6 tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA compare
BWI76_RS06190 +1.2 1.2 hypothetical protein compare
BWI76_RS19730 +1.1 3.2 1-phosphofructokinase compare
BWI76_RS19735 +1.1 7.5 bifunctional PTS fructose transporter subunit IIA/HPr protein compare
BWI76_RS18780 +1.1 2.8 D-alanyl-D-alanine carboxypeptidase compare
BWI76_RS18385 +1.1 2.1 hypothetical protein compare
BWI76_RS16900 +1.1 0.9 4-hydroxy-2-oxovalerate aldolase compare
BWI76_RS06465 +1.1 2.7 IclR family transcriptional regulator compare
BWI76_RS11390 +1.1 2.4 iron dicitrate transport regulator FecR compare
BWI76_RS27550 +1.1 1.7 hypothetical protein compare
BWI76_RS18575 +1.1 2.8 transcriptional regulator compare
BWI76_RS00590 +1.1 1.5 hypothetical protein compare
BWI76_RS14980 +1.1 1.4 hypothetical protein compare
BWI76_RS01995 +1.1 1.4 AraC family transcriptional regulator compare
BWI76_RS27385 +1.1 4.7 orotate phosphoribosyltransferase compare
BWI76_RS16920 +1.0 2.1 3-(2,3-dihydroxyphenyl)propionate dioxygenase compare
BWI76_RS25915 +1.0 2.1 protein SlyX compare
BWI76_RS15920 +1.0 1.9 hypothetical protein compare
BWI76_RS19895 +1.0 3.2 bifunctional transcriptional regulator/O6-methylguanine-DNA methyltransferase compare
BWI76_RS03665 +1.0 1.7 ABC transporter ATP-binding protein compare
BWI76_RS11010 +1.0 1.9 30S ribosomal protein S5 alanine N-acetyltransferase compare
BWI76_RS19725 +1.0 3.8 PTS fructose transporter subunit EIIBC compare
BWI76_RS01585 +1.0 4.9 transcriptional regulator compare
BWI76_RS14970 +1.0 1.8 pyrroline-5-carboxylate reductase compare
BWI76_RS15135 +1.0 2.0 hypothetical protein compare
BWI76_RS14650 +1.0 2.2 helix-turn-helix transcriptional regulator compare
BWI76_RS07865 +1.0 2.1 methylthioribulose 1-phosphate dehydratase compare
BWI76_RS16935 +1.0 1.3 shikimate dehydrogenase compare
BWI76_RS27455 +1.0 2.4 DUF805 domain-containing protein compare
BWI76_RS03310 +1.0 1.5 AraC family transcriptional regulator compare
BWI76_RS00240 +1.0 2.3 FMN-binding protein MioC compare
BWI76_RS25080 +1.0 5.0 tRNA pseudouridine(55) synthase compare
BWI76_RS15290 +1.0 1.5 transcriptional regulator compare
BWI76_RS01195 +0.9 0.9 membrane protein compare
BWI76_RS01630 +0.9 1.3 16S ribosomal RNA compare
BWI76_RS17895 +0.9 2.5 PTS mannose/fructose/sorbose transporter subunit IIC compare
BWI76_RS09450 +0.9 1.4 30S ribosomal protein S6--L-glutamate ligase compare
BWI76_RS25655 +0.9 2.6 DNA topoisomerase type IA zn finger domain-containing protein compare
BWI76_RS08600 +0.9 3.5 3-deoxy-7-phosphoheptulonate synthase compare
BWI76_RS07740 +0.9 1.9 Fe2+-enterobactin ABC transporter substrate-binding protein compare
BWI76_RS24010 +0.9 2.0 hypothetical protein compare
BWI76_RS12420 +0.9 1.3 peptide ABC transporter substrate-binding protein SapA compare
BWI76_RS13685 +0.9 2.0 IclR family transcriptional regulator compare
BWI76_RS25000 +0.9 1.6 malonate decarboxylase acyl carrier protein compare
BWI76_RS12485 +0.9 2.5 TyrR family transcriptional regulator compare
BWI76_RS13125 +0.9 4.2 3-hydroxyacyl-CoA dehydrogenase compare
BWI76_RS11675 +0.9 1.1 arginine N-succinyltransferase compare
BWI76_RS18360 +0.9 2.1 aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase family protein compare
BWI76_RS25280 +0.9 2.0 RNase adaptor protein RapZ compare
BWI76_RS16015 +0.9 1.9 pheromone autoinducer 2 transporter compare
BWI76_RS14680 +0.9 2.3 SefF compare
BWI76_RS06540 +0.8 2.7 DNA-binding protein HU-beta compare
BWI76_RS11365 +0.8 1.5 iron ABC transporter compare
BWI76_RS17350 +0.8 1.9 DNA-binding response regulator compare
BWI76_RS13420 +0.8 1.2 ABC transporter permease compare
BWI76_RS11700 +0.8 1.1 hypothetical protein compare
BWI76_RS16050 +0.8 2.7 malonate decarboxylase holo-ACP synthase compare
BWI76_RS07380 +0.8 2.6 hypothetical protein compare
BWI76_RS19920 +0.8 3.6 hybrid sensor histidine kinase/response regulator compare
BWI76_RS24885 +0.8 1.3 PTS galactitol transporter subunit IIB compare
BWI76_RS18240 +0.8 1.6 L-arabinose ABC transporter permease AraH compare
BWI76_RS15015 +0.8 1.1 DUF2132 domain-containing protein compare
BWI76_RS14665 +0.8 0.7 minor fimbrial subunit YfcQ compare
BWI76_RS15220 +0.8 1.7 L-lactate dehydrogenase compare
BWI76_RS05985 +0.8 2.0 branched-chain amino acid ABC transporter permease compare
BWI76_RS17900 +0.8 2.4 PTS mannose transporter subunit IID compare
BWI76_RS19770 +0.8 1.1 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase compare
BWI76_RS18125 +0.8 2.2 murein DD-endopeptidase MepM compare
BWI76_RS25070 +0.8 1.3 hypothetical protein compare
BWI76_RS18070 +0.8 3.1 DNA polymerase III subunit epsilon compare
BWI76_RS10875 +0.8 1.3 quercetin 2,3-dioxygenase compare
BWI76_RS16690 +0.8 2.3 peptide ABC transporter permease compare
BWI76_RS25285 +0.8 0.9 HPr family phosphocarrier protein compare
BWI76_RS01545 +0.8 1.6 thiamine biosynthesis protein ThiS compare
BWI76_RS16040 +0.8 1.2 biotin-independent malonate decarboxylase subunit gamma compare
BWI76_RS23015 +0.8 1.3 cobalt transporter ATP-binding subunit compare
BWI76_RS20795 +0.8 1.0 ethanolamine catabolic microcompartment shell protein EutN compare
BWI76_RS17805 +0.8 1.0 membrane protein compare
BWI76_RS00225 +0.8 3.3 16S rRNA methyltransferase G compare
BWI76_RS17375 +0.8 1.8 nitrate ABC transporter, permease protein compare
BWI76_RS09240 +0.7 1.3 phosphoadenosine phosphosulfate reductase compare
BWI76_RS16320 +0.7 3.8 methionine ABC transporter substrate-binding protein compare
BWI76_RS14155 +0.7 1.8 transketolase compare
BWI76_RS16470 +0.7 1.2 transcriptional repressor NemR compare
BWI76_RS16315 +0.7 1.8 SirA-like protein compare
BWI76_RS12925 +0.7 2.8 efflux transporter periplasmic adaptor subunit compare
BWI76_RS13175 +0.7 1.6 NodT family RND efflux system outer membrane lipoprotein compare
BWI76_RS11250 +0.7 1.0 spermidine/putrescine ABC transporter permease PotB compare
BWI76_RS19310 +0.7 1.2 ABC transporter permease compare
BWI76_RS13805 +0.7 1.4 inorganic diphosphatase compare
BWI76_RS13730 +0.7 1.5 hypothetical protein compare
BWI76_RS17915 +0.7 2.7 membrane protein compare
BWI76_RS13450 +0.7 2.5 acyl-CoA thioesterase compare
BWI76_RS17890 +0.7 3.1 PTS mannose transporter subunit EIIAB compare
BWI76_RS16485 +0.7 1.2 ribonuclease T compare
BWI76_RS14230 +0.7 1.6 flavin monoamine oxidase family protein compare
BWI76_RS17045 +0.7 0.9 hypothetical protein compare
BWI76_RS26280 +0.7 2.5 hypothetical protein compare
BWI76_RS06630 +0.7 1.8 hypothetical protein compare
BWI76_RS07610 +0.7 2.3 choline dehydrogenase compare
BWI76_RS12470 +0.7 1.1 thiosulfate sulfurtransferase PspE compare
BWI76_RS27390 +0.7 2.3 ribonuclease PH compare
BWI76_RS24460 +0.7 2.4 bifunctional glutamine synthetase adenylyltransferase/deadenyltransferase compare
BWI76_RS27915 +0.7 0.9 YceK/YidQ family lipoprotein compare
BWI76_RS09475 +0.7 1.6 putrescine ABC transporter permease PotI compare
BWI76_RS24035 +0.7 3.4 hypothetical protein compare
BWI76_RS06665 +0.7 0.8 membrane protein compare
BWI76_RS24920 +0.7 1.6 YraN family protein compare
BWI76_RS08630 +0.7 2.4 molybdate ABC transporter ATP-binding protein ModF compare
BWI76_RS24180 +0.7 1.2 hypothetical protein compare
BWI76_RS10255 +0.7 1.5 dihydrodipicolinate synthase family protein compare
BWI76_RS03595 +0.7 0.9 ethanolamine utilization protein EutM compare
BWI76_RS00995 +0.7 2.4 peptidyl-prolyl cis-trans isomerase compare
BWI76_RS25870 +0.7 1.3 elongation factor Tu compare
BWI76_RS20310 +0.6 1.7 hypothetical protein compare
BWI76_RS16870 +0.6 1.3 LysR family transcriptional regulator compare
BWI76_RS17570 +0.6 1.6 iron-sulfur-binding protein compare
BWI76_RS19160 +0.6 3.3 histidine kinase compare
BWI76_RS19235 +0.6 3.0 polar amino acid ABC transporter inner membrane subunit compare
BWI76_RS12910 +0.6 1.0 3,4-dihydroxyphenylacetate 2,3-dioxygenase compare
BWI76_RS00765 +0.6 2.3 DNA-binding transcriptional regulator CytR compare
BWI76_RS21395 +0.6 1.6 DTW domain-containing protein compare
BWI76_RS27825 +0.6 1.5 hypothetical protein compare
BWI76_RS23255 +0.6 1.8 prepilin-type cleavage/methylation domain-containing protein compare
BWI76_RS19750 +0.6 1.5 elongation factor P-like protein YeiP compare
BWI76_RS13110 +0.6 2.2 phenylacetic acid degradation protein compare
BWI76_RS16190 +0.6 1.5 universal stress protein UspE compare
BWI76_RS16200 +0.6 1.5 NAD(P) transhydrogenase subunit beta compare
BWI76_RS04975 +0.6 0.8 PTS fructose subfamily transporter subunit IIA compare
BWI76_RS13710 +0.6 2.3 benzoate 1,2-dioxygenase small subunit compare
BWI76_RS08640 +0.6 1.3 multidrug efflux pump-associated protein, AcrZ family compare
BWI76_RS14320 +0.6 1.5 hypothetical protein compare
BWI76_RS14095 +0.6 2.1 hypothetical protein compare
BWI76_RS26285 +0.6 2.7 glycerophosphodiester phosphodiesterase compare
BWI76_RS22375 +0.6 1.1 pectin acetylesterase compare
BWI76_RS17390 +0.6 0.6 DsrE family protein compare
BWI76_RS16260 +0.6 1.3 two-component sensor histidine kinase compare
BWI76_RS19835 +0.6 2.9 nucleoid-associated protein YejK compare
BWI76_RS14515 +0.6 1.9 yersiniabactin-iron ABC transporter permease ATP-binding protein YbtQ compare
BWI76_RS06405 +0.6 0.9 2-dehydropantoate 2-reductase compare
BWI76_RS09570 +0.6 1.5 hydroxylamine reductase compare
BWI76_RS02940 +0.6 2.8 RpiR family transcriptional regulator compare
BWI76_RS12205 +0.6 1.8 hypothetical protein compare
BWI76_RS08275 +0.6 0.8 LexA regulated protein compare
BWI76_RS12295 +0.6 1.9 hypothetical protein compare
BWI76_RS00095 +0.6 1.4 DNA-binding transcriptional regulator compare
BWI76_RS10645 +0.6 1.9 phytanoyl-CoA dioxygenase compare
BWI76_RS00640 +0.6 1.5 L-rhamnose mutarotase compare
BWI76_RS14525 +0.6 2.0 AraC family transcriptional regulator compare
BWI76_RS07945 +0.6 2.6 alkyl hydroperoxide reductase subunit F compare
BWI76_RS24470 +0.6 3.0 hypothetical protein compare
BWI76_RS13870 +0.6 1.0 hypothetical protein compare
BWI76_RS07230 +0.6 2.1 transcriptional regulator compare
BWI76_RS17380 +0.6 0.8 nitrate transporter component compare
BWI76_RS11135 +0.6 2.2 ferric-rhodotorulic acid/ferric-coprogen receptor FhuE compare
BWI76_RS06740 +0.6 0.9 50S ribosomal protein L36 compare
BWI76_RS11780 +0.6 1.2 2-deoxyglucose-6-phosphatase compare
BWI76_RS21905 +0.6 1.8 class II aldolase compare
BWI76_RS11125 +0.6 0.8 metal-dependent hydrolase compare
BWI76_RS17910 +0.6 1.8 hypothetical protein compare
BWI76_RS13330 +0.6 0.9 tellurite resistance methyltransferase TehB compare
BWI76_RS19145 +0.6 1.2 formate dehydrogenase cytochrome b556 subunit compare
BWI76_RS19325 +0.6 0.9 mandelate racemase compare
BWI76_RS15965 +0.6 1.6 MFS transporter compare
BWI76_RS23670 +0.6 1.2 alkaline phosphatase compare
BWI76_RS00720 +0.6 1.1 DNA-binding response regulator compare
BWI76_RS01530 +0.6 1.6 2-iminoacetate synthase ThiH compare
BWI76_RS07540 +0.6 2.0 dipeptide ABC transporter ATP-binding protein DppD compare
BWI76_RS20390 +0.6 0.7 erythronate-4-phosphate dehydrogenase compare
BWI76_RS20605 +0.6 2.7 purine-nucleoside phosphorylase compare
BWI76_RS24080 +0.6 0.9 DUF179 domain-containing protein compare
BWI76_RS08800 +0.6 1.6 phosphoethanolamine transferase EptA compare
BWI76_RS17565 +0.6 1.3 hypothetical protein compare
BWI76_RS07745 +0.6 1.9 isochorismate synthase EntC compare
BWI76_RS13800 +0.6 2.0 zinc-dependent alcohol dehydrogenase compare


Specific Phenotypes

For 9 genes in this experiment

For carbon source D-Raffinose pentahydrate in Klebsiella michiganensis M5al

For carbon source D-Raffinose pentahydrate across organisms