Experiment set5IT032 for Methanococcus maripaludis S2

Compare to:

Formate with cyanide 50 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS03315 -5.5 -3.1 ferrous iron transport protein A compare
MMP_RS01175 -3.9 -7.1 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS01020 -3.5 -2.6 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS06685 -3.2 -17.5 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS06700 -3.2 -17.8 hypothetical protein compare
MMP_RS07005 -3.0 -1.4 4Fe-4S binding protein compare
MMP_RS06680 -2.9 -16.3 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS06105 -2.8 -12.1 hydrogenase maturation peptidase HycI compare
MMP_RS00300 -2.7 -1.5 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS08820 -2.5 -9.5 hypothetical protein compare
MMP_RS08635 -2.5 -3.5 UbiA family prenyltransferase compare
MMP_RS01005 -2.5 -3.0 riboflavin synthase compare
MMP_RS02280 -2.5 -2.3 DUF211 domain-containing protein compare
MMP_RS01755 -2.5 -2.7 DUF2097 domain-containing protein compare
MMP_RS06355 -2.4 -4.1 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS08745 -2.4 -8.9 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS06345 -2.3 -12.0 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS01365 -2.2 -5.4 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS07380 -2.2 -3.0 transcription elongation factor Spt5 compare
MMP_RS04685 -2.1 -6.7 DUF126 domain-containing protein compare
MMP_RS07635 -2.1 -11.7 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS07575 -2.1 -5.0 RNA ligase partner protein compare
MMP_RS09020 -2.1 -2.5 hypothetical protein compare
MMP_RS04780 -2.1 -4.6 ribonuclease P compare
MMP_RS00515 -2.0 -1.9 DUF655 domain-containing protein compare
MMP_RS00115 -2.0 -14.4 radical SAM protein compare
MMP_RS01225 -2.0 -7.1 DUF5379 domain-containing protein compare
MMP_RS05515 -1.9 -10.9 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS03025 -1.9 -9.1 molybdenum cofactor guanylyltransferase compare
MMP_RS06400 -1.9 -3.7 4Fe-4S binding protein compare
MMP_RS06295 -1.9 -7.3 methanogenesis marker 14 protein compare
MMP_RS01265 -1.9 -3.5 hypothetical protein compare
MMP_RS02195 -1.9 -5.5 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS01500 -1.9 -4.6 CBS domain-containing protein compare
MMP_RS08210 -1.9 -3.6 phosphatidylglycerophosphatase A compare
MMP_RS03400 -1.8 -4.7 archease compare
MMP_RS07525 -1.8 -8.9 4Fe-4S binding protein compare
MMP_RS08720 -1.7 -2.4 4Fe-4S binding protein compare
MMP_RS06285 -1.7 -3.8 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS08715 -1.7 -2.9 formylmethanofuran dehydrogenase subunit B compare
MMP_RS06715 -1.7 -13.5 cache domain-containing protein compare
MMP_RS06720 -1.7 -11.9 response regulator transcription factor compare
MMP_RS07445 -1.7 -7.2 helix-turn-helix domain-containing protein compare
MMP_RS06895 -1.7 -3.1 selenocysteine-specific translation elongation factor compare
MMP_RS06350 -1.7 -8.0 HesA/MoeB/ThiF family protein compare
MMP_RS06270 -1.6 -6.2 TIGR00300 family protein compare
MMP_RS05920 -1.6 -1.5 50S ribosomal protein L37e compare
MMP_RS02010 -1.6 -9.7 PHP domain-containing protein compare
MMP_RS00685 -1.6 -5.6 2-phospho-L-lactate guanylyltransferase compare
MMP_RS06340 -1.6 -7.4 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS06705 -1.6 -6.2 formate/nitrite transporter family protein compare
MMP_RS03015 -1.6 -9.4 GTP 3' 8-cyclase MoaA compare
MMP_RS08460 -1.6 -3.3 proteasome-activating nucleotidase compare
MMP_RS06630 -1.5 -1.9 UPF0058 family protein compare
MMP_RS03600 -1.5 -2.8 triose-phosphate isomerase compare
MMP_RS06730 -1.5 -2.4 phosphopantothenate/pantothenate synthetase compare
MMP_RS00895 -1.5 -4.0 hypothetical protein compare
MMP_RS06120 -1.5 -2.9 UPF0147 family protein compare
MMP_RS06020 -1.5 -4.6 archaeoflavoprotein AfpA compare
MMP_RS02135 -1.4 -5.1 DUF5612 domain-containing protein compare
MMP_RS01220 -1.4 -6.8 hypothetical protein compare
MMP_RS05875 -1.4 -4.1 hydroxyethylthiazole kinase compare
MMP_RS03640 -1.4 -5.6 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS07845 -1.3 -3.1 LL-diaminopimelate aminotransferase compare
MMP_RS02235 -1.3 -10.9 CBS domain-containing protein compare
MMP_RS01325 -1.3 -2.9 dihydroneopterin aldolase family protein compare
MMP_RS06475 -1.3 -5.2 FAD-dependent oxidoreductase compare
MMP_RS07385 -1.2 -2.0 protein translocase SEC61 complex subunit gamma compare
MMP_RS07765 -1.2 -6.6 sodium:alanine symporter family protein compare
MMP_RS04585 -1.2 -7.5 AIR synthase related protein compare
MMP_RS05845 -1.2 -2.8 tRNA-intron lyase compare
MMP_RS05540 -1.2 -3.7 hypothetical protein compare
MMP_RS02240 -1.1 -4.1 methanogenesis marker 7 protein compare
MMP_RS06230 -1.1 -2.1 helix-turn-helix domain-containing protein compare
MMP_RS01380 -1.1 -5.1 PHP domain-containing protein compare
MMP_RS08650 -1.1 -2.5 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS03445 -1.1 -1.6 methanogenesis marker 17 protein compare
MMP_RS06865 -1.1 -1.8 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS00305 -1.1 -1.7 phosphoribosyl-ATP diphosphatase compare
MMP_RS02355 -1.1 -2.6 30S ribosomal protein S27ae compare
MMP_RS03205 -1.0 -1.7 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS00695 -1.0 -1.4 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS07600 -1.0 -2.6 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS00295 -1.0 -3.1 gamma carbonic anhydrase family protein compare
MMP_RS02145 -1.0 -4.3 winged helix-turn-helix transcriptional regulator compare
MMP_RS05245 -1.0 -7.1 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS00320 -1.0 -2.4 class I SAM-dependent methyltransferase compare
MMP_RS04710 -1.0 -2.2 hypothetical protein compare
MMP_RS00110 -1.0 -3.8 hypothetical protein compare
MMP_RS01720 -1.0 -1.0 replication factor C large subunit compare
MMP_RS07390 -1.0 -2.4 cell division protein FtsZ compare
MMP_RS06110 -0.9 -2.5 ATP-dependent protease LonB compare
MMP_RS05815 -0.9 -2.1 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS01250 -0.9 -4.5 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS04955 -0.9 -4.2 DNA topoisomerase I compare
MMP_RS04775 -0.9 -2.9 adenosylhomocysteinase compare
MMP_RS01795 -0.9 -2.1 methanogenesis marker 6 protein compare
MMP_RS04890 -0.9 -1.1 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS00620 -0.9 -4.6 4Fe-4S binding protein compare
MMP_RS01985 -0.9 -4.2 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS06625 -0.9 -2.4 DNA primase compare
MMP_RS03580 -0.9 -3.1 signal recognition particle-docking protein FtsY compare
MMP_RS05765 -0.9 -5.3 M42 family metallopeptidase compare
MMP_RS06315 -0.9 -1.3 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS02165 -0.9 -4.3 tRNA-dihydrouridine synthase compare
MMP_RS03475 -0.9 -0.7 hypothetical protein compare
MMP_RS03555 -0.9 -6.3 transcriptional regulator compare
MMP_RS01545 -0.9 -1.1 CBS domain-containing protein compare
MMP_RS03435 -0.8 -1.7 ketol-acid reductoisomerase compare
MMP_RS00810 -0.8 -4.3 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS07545 -0.8 -0.8 HTH domain-containing protein compare
MMP_RS01960 -0.8 -0.9 hypothetical protein compare
MMP_RS03960 -0.8 -0.9 hypothetical protein compare
MMP_RS05835 -0.8 -1.1 secondary thiamine-phosphate synthase enzyme YjbQ compare
MMP_RS07365 -0.8 -5.8 2-phosphoglycerate kinase compare
MMP_RS02340 -0.8 -1.7 DNA-directed RNA polymerase subunit E'' compare
MMP_RS03035 -0.8 -2.9 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS05430 -0.8 -3.5 TIGR00288 family NYN domain-containing protein compare
MMP_RS02345 -0.8 -2.2 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS08200 -0.7 -6.4 archaeosine synthase subunit alpha compare
MMP_RS07200 -0.7 -3.8 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS05315 -0.7 -1.4 hypothetical protein compare
MMP_RS01610 -0.7 -2.3 hypothetical protein compare
MMP_RS08915 -0.7 -2.3 2 5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase compare
MMP_RS01180 -0.7 -0.9 XTP/dITP diphosphatase compare
MMP_RS02190 -0.7 -1.4 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS03095 -0.6 -4.2 diphthine synthase compare
MMP_RS05510 -0.6 -3.4 Rrf2 family transcriptional regulator compare
MMP_RS01800 -0.6 -3.0 TIGR00303 family protein compare
MMP_RS07850 -0.6 -2.3 prephenate dehydratase compare
MMP_RS02930 -0.6 -2.3 class I SAM-dependent methyltransferase compare
MMP_RS02170 -0.6 -3.1 CBS domain-containing protein compare
MMP_RS01865 -0.6 -1.5 GPR1/FUN34/YaaH family transporter compare
MMP_RS05550 -0.6 -0.8 cation:proton antiporter compare
MMP_RS01980 -0.6 -4.5 trimeric intracellular cation channel family protein compare
MMP_RS04605 -0.6 -2.1 cobalt ECF transporter T component CbiQ compare
MMP_RS04870 -0.6 -2.6 TIGR02253 family HAD-type hydrolase compare
MMP_RS03155 -0.6 -3.6 precorrin-6A reductase compare
MMP_RS02130 -0.6 -2.4 zinc metalloprotease HtpX compare
MMP_RS08300 -0.6 -0.8 metal-sulfur cluster assembly factor compare
MMP_RS03385 -0.5 -1.0 cation diffusion facilitator family transporter compare
MMP_RS08435 -0.5 -1.4 Era-like GTP-binding protein compare
MMP_RS02800 -0.5 -2.9 nucleotidyltransferase domain-containing protein compare
MMP_RS00290 -0.5 -4.2 hypothetical protein compare
MMP_RS00120 -0.5 -2.7 LysR family transcriptional regulator compare
MMP_RS02230 -0.5 -3.8 sodium-dependent transporter compare
MMP_RS04305 -0.5 -1.9 hypothetical protein compare
MMP_RS00720 -0.5 -3.2 metal-dependent hydrolase compare
MMP_RS07535 -0.5 -3.4 4Fe-4S binding protein compare
MMP_RS07580 -0.5 -1.8 DUF356 domain-containing protein compare
MMP_RS07730 -0.5 -1.4 pyruvate synthase subunit beta compare
MMP_RS07605 -0.5 -2.1 diadenylate cyclase compare
MMP_RS03110 -0.5 -2.3 glycosyltransferase family 2 protein compare
MMP_RS02875 -0.5 -3.7 chorismate pyruvate-lyase family protein compare
MMP_RS08790 -0.5 -0.7 translation initiation factor IF-2 subunit alpha compare
MMP_RS08165 -0.5 -0.6 phosphoglycerate dehydrogenase compare
MMP_RS03700 -0.5 -2.9 sodium:proton antiporter compare
MMP_RS00570 -0.5 -2.2 protein-L-isoaspartate O-methyltransferase compare
MMP_RS00315 -0.5 -2.7 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS08645 -0.5 -2.6 UPF0179 family protein compare
MMP_RS05445 -0.4 -3.1 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS00060 -0.4 -0.7 3-dehydroquinate synthase II compare
MMP_RS00475 -0.4 -3.5 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS06860 -0.4 -1.6 4Fe-4S binding protein compare
MMP_RS05535 -0.4 -2.4 hypothetical protein compare
MMP_RS06200 -0.4 -3.3 M24 family metallopeptidase compare
MMP_RS01240 -0.4 -0.6 7-cyano-7-deazaguanine synthase QueC compare
MMP_RS05925 -0.4 -2.3 small nuclear ribonucleoprotein compare
MMP_RS06885 -0.4 -1.3 50S ribosome-binding GTPase compare
MMP_RS07875 -0.4 -2.2 hypothetical protein compare
MMP_RS03470 -0.4 -3.2 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS00675 -0.4 -0.8 nitroreductase family protein compare
MMP_RS00455 -0.4 -3.3 orotate phosphoribosyltransferase-like protein compare
MMP_RS01780 -0.4 -3.1 TrmJ/YjtD family RNA methyltransferase compare
MMP_RS00945 -0.4 -0.8 PadR family transcriptional regulator compare
MMP_RS08320 -0.4 -2.2 molybdopterin molybdotransferase MoeA compare
MMP_RS07755 -0.4 -0.9 DUF555 domain-containing protein compare
MMP_RS00985 -0.4 -2.4 CDC48 family AAA ATPase compare
MMP_RS07710 -0.4 -2.6 cell division protein FtsZ compare
MMP_RS05545 -0.4 -1.8 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS01665 -0.4 -1.7 DUF2111 domain-containing protein compare
MMP_RS03685 -0.4 -3.0 Mrp/NBP35 family ATP-binding protein compare
MMP_RS07620 -0.4 -1.5 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS07735 -0.4 -0.6 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS01150 -0.4 -1.4 aldo/keto reductase compare
MMP_RS02900 -0.4 -0.3 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS01600 -0.4 -0.7 50S ribosomal protein L15e compare
MMP_RS09055 -0.4 -0.7 CAP domain-containing protein compare
MMP_RS05555 -0.4 -1.0 DUF4040 domain-containing protein compare
MMP_RS01495 -0.4 -3.0 TraB/GumN family protein compare
MMP_RS00520 -0.4 -1.0 RNA polymerase Rpb4 family protein compare
MMP_RS04875 -0.4 -1.8 energy-converting hydrogenase B subunit P compare
MMP_RS01155 -0.4 -1.6 XRE family transcriptional regulator compare
MMP_RS06310 -0.4 -2.0 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS07750 -0.4 -1.4 DUF357 domain-containing protein compare
MMP_RS04620 -0.4 -2.5 cobalt transporter CbiM compare
MMP_RS08940 -0.4 -0.8 MetS family NSS transporter small subunit compare
MMP_RS00915 -0.4 -2.2 DUF116 domain-containing protein compare
MMP_RS06365 -0.4 -1.3 hypothetical protein compare
MMP_RS06770 -0.4 -2.6 DHH family phosphoesterase compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Sodium cyanide across organisms