Experiment set5IT032 for Klebsiella michiganensis M5al

Compare to:

D-Maltose monohydrate carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS18930 -8.8 -6.1 histidinol-phosphate transaminase compare
BWI76_RS04465 -6.8 -4.7 carbamoyl-phosphate synthase small subunit compare
BWI76_RS18920 -6.5 -4.5 ATP phosphoribosyltransferase compare
BWI76_RS09755 -6.2 -7.4 phosphoserine transaminase compare
BWI76_RS20355 -6.2 -4.7 colicin V production protein compare
BWI76_RS23920 -6.0 -5.8 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS18940 -5.9 -7.0 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS04160 -5.9 -5.9 phosphoserine phosphatase compare
BWI76_RS20895 -5.9 -5.8 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS23360 -5.9 -4.1 diaminopimelate decarboxylase compare
BWI76_RS05840 -5.8 -6.2 glutamate 5-kinase compare
BWI76_RS26085 -5.8 -4.0 3-dehydroquinate synthase compare
BWI76_RS00980 -5.8 -12.8 PLP-dependent threonine dehydratase compare
BWI76_RS00990 -5.8 -10.3 ketol-acid reductoisomerase compare
BWI76_RS08385 -5.7 -3.4 citrate (Si)-synthase compare
BWI76_RS18935 -5.7 -9.5 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS04250 -5.6 -10.0 homoserine kinase compare
BWI76_RS04470 -5.6 -11.3 carbamoyl phosphate synthase large subunit compare
BWI76_RS02995 -5.4 -8.6 aspartate carbamoyltransferase compare
BWI76_RS04645 -5.4 -6.6 3-dehydroquinase compare
BWI76_RS00805 -5.3 -5.4 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS23220 -5.2 -9.2 amino-acid N-acetyltransferase compare
BWI76_RS00965 -5.1 -2.2 acetolactate synthase 2 small subunit compare
BWI76_RS00855 -5.1 -10.3 argininosuccinate lyase compare
BWI76_RS17720 -5.1 -2.2 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS04675 -5.0 -7.3 3-isopropylmalate dehydrogenase compare
BWI76_RS00835 -5.0 -14.8 phosphoenolpyruvate carboxylase compare
BWI76_RS27385 -4.9 -8.2 orotate phosphoribosyltransferase compare
BWI76_RS18955 -4.9 -6.1 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS04245 -4.8 -14.6 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS09645 -4.8 -2.1 thioredoxin-disulfide reductase compare
BWI76_RS04685 -4.7 -10.6 putative leucine operon leader peptide compare
BWI76_RS18950 -4.7 -4.3 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS01210 -4.7 -4.1 tyrosine recombinase XerC compare
BWI76_RS04665 -4.7 -20.1 3-isopropylmalate dehydratase small subunit compare
BWI76_RS03010 -4.6 -8.0 ornithine carbamoyltransferase compare
BWI76_RS20350 -4.6 -8.4 amidophosphoribosyltransferase compare
BWI76_RS04255 -4.6 -12.5 threonine synthase compare
BWI76_RS01655 -4.5 -8.5 homoserine O-succinyltransferase compare
BWI76_RS26460 -4.5 -8.0 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS21310 -4.5 -2.0 DNA repair protein RecO compare
BWI76_RS00850 -4.4 -8.7 acetylglutamate kinase compare
BWI76_RS00785 -4.4 -7.2 cystathionine gamma-synthase compare
BWI76_RS26165 -4.4 -12.3 Glycogen phosphorylase (EC 2.4.1.1) (from data) conserved
BWI76_RS00845 -4.3 -10.6 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS04670 -4.3 -11.5 3-isopropylmalate dehydratase large subunit compare
BWI76_RS11860 -4.3 -7.6 anthranilate synthase component I compare
BWI76_RS11850 -4.3 -10.3 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS26160 -4.3 -12.7 4-alpha-glucanotransferase (EC 2.4.1.25) (from data) conserved
BWI76_RS18925 -4.2 -6.0 histidinol dehydrogenase compare
BWI76_RS22755 -4.2 -8.6 phosphoadenosine phosphosulfate reductase compare
BWI76_RS21475 -4.1 -7.0 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS11855 -4.1 -6.6 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS21465 -4.1 -5.8 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS22760 -4.0 -8.6 sulfite reductase subunit beta compare
BWI76_RS26455 -3.9 -3.6 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS11965 -3.9 -4.9 orotidine-5'-phosphate decarboxylase compare
BWI76_RS22805 -3.9 -9.8 GTP diphosphokinase compare
BWI76_RS24285 -3.9 -9.1 cystathionine beta-lyase compare
BWI76_RS04680 -3.9 -10.8 2-isopropylmalate synthase compare
BWI76_RS11840 -3.9 -5.9 tryptophan synthase subunit alpha compare
BWI76_RS01615 -3.9 -9.0 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS01800 -3.8 -5.2 glucose-6-phosphate isomerase compare
BWI76_RS09910 -3.8 -17.3 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS00400 -3.8 -2.6 glutamine synthetase compare
BWI76_RS05835 -3.8 -3.9 gamma-glutamyl-phosphate reductase compare
BWI76_RS04240 -3.8 -3.4 thr operon leader peptide compare
BWI76_RS20435 -3.7 -2.3 chorismate synthase compare
BWI76_RS00985 -3.7 -8.0 transcriptional regulator IlvY compare
BWI76_RS22765 -3.6 -13.7 sulfite reductase subunit alpha compare
BWI76_RS07070 -3.6 -7.2 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS21265 -3.6 -13.5 phosphoribosylformylglycinamidine synthase compare
BWI76_RS02735 -3.5 -5.3 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS01610 -3.5 -7.1 phosphoribosylamine--glycine ligase compare
BWI76_RS10990 -3.5 -2.9 dihydroorotase compare
BWI76_RS23365 -3.4 -5.8 LysR family transcriptional regulator compare
BWI76_RS07065 -3.4 -10.7 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS00975 -3.4 -6.5 dihydroxy-acid dehydratase compare
BWI76_RS25115 -3.3 -7.1 argininosuccinate synthase compare
BWI76_RS09760 -3.3 -4.5 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS20965 -3.3 -7.2 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS05200 -3.3 -3.8 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS15825 -3.2 -3.9 hypothetical protein compare
BWI76_RS02410 -3.2 -2.2 EF-P beta-lysylation protein EpmB compare
BWI76_RS01185 -3.2 -3.1 adenylate cyclase compare
BWI76_RS22690 -3.1 -3.3 adenylyl-sulfate kinase compare
BWI76_RS27430 -2.9 -2.5 (p)ppGpp synthetase compare
BWI76_RS10745 -2.9 -1.8 hypothetical protein compare
BWI76_RS09660 -2.9 -2.7 DNA translocase FtsK compare
BWI76_RS11845 -2.8 -3.8 tryptophan synthase subunit beta compare
BWI76_RS00345 -2.8 -4.6 protein disulfide oxidoreductase DsbA compare
BWI76_RS01825 -2.8 -9.8 maltose ABC transporter, permease component 1 (MalF) (from data) conserved
BWI76_RS05015 -2.8 -3.7 transcriptional regulator compare
BWI76_RS20650 -2.8 -1.9 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS21370 -2.8 -2.9 ATP-dependent RNA helicase SrmB compare
BWI76_RS23240 -2.7 -4.4 exonuclease V subunit gamma compare
BWI76_RS26055 -2.5 -9.0 siroheme synthase compare
BWI76_RS26170 -2.5 -12.9 transcriptional regulator MalT conserved
BWI76_RS23230 -2.5 -4.3 exodeoxyribonuclease V subunit beta compare
BWI76_RS01840 -2.4 -3.9 maltose ABC transporter, ATPase component (MalK) (from data) compare
BWI76_RS01820 -2.4 -12.7 maltose ABC transporter, permease component 2 (MalG) (from data) conserved
BWI76_RS00180 -2.4 -2.8 F0F1 ATP synthase subunit epsilon compare
BWI76_RS25645 -2.2 -7.8 shikimate dehydrogenase compare
BWI76_RS15760 -2.1 -2.3 hypothetical protein compare
BWI76_RS01830 -2.1 -7.0 maltose ABC transporter, substrate-binding component MalE (from data) conserved
BWI76_RS25320 -2.0 -6.9 glutamate synthase compare
BWI76_RS04705 -2.0 -6.7 DNA-binding transcriptional regulator FruR compare
BWI76_RS20440 -2.0 -1.3 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS27390 -2.0 -3.5 ribonuclease PH compare
BWI76_RS01835 -1.9 -5.3 chemotaxis protein CheW compare
BWI76_RS02530 -1.9 -2.4 tRNA dimethylallyltransferase compare
BWI76_RS03665 -1.9 -2.7 ABC transporter ATP-binding protein compare
BWI76_RS16315 -1.8 -2.6 SirA-like protein compare
BWI76_RS26570 -1.8 -4.1 anion permease compare
BWI76_RS26000 -1.7 -5.9 aspartate aminotransferase family protein compare
BWI76_RS23265 -1.7 -4.5 hypothetical protein compare
BWI76_RS06185 -1.7 -7.6 shikimate kinase II compare
BWI76_RS23480 -1.7 -9.8 EAL domain-containing protein compare
BWI76_RS20380 -1.7 -1.6 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS08405 -1.7 -3.9 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS20640 -1.7 -4.1 cysteine synthase A compare
BWI76_RS09670 -1.6 -4.5 recombination factor protein RarA compare
BWI76_RS27875 -1.5 -2.1 membrane protein compare
BWI76_RS06525 -1.5 -3.6 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS08980 -1.5 -1.5 DNA starvation/stationary phase protection protein compare
BWI76_RS00960 -1.5 -4.4 acetolactate synthase 2 catalytic subunit compare
BWI76_RS27440 -1.5 -3.9 DNA helicase RecG compare
BWI76_RS04715 -1.5 -2.2 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS00385 -1.4 -6.8 nitrogen assimilation regulatory protein compare
BWI76_RS25335 -1.4 -2.1 stringent starvation protein A compare
BWI76_RS18165 -1.4 -2.0 NUDIX pyrophosphatase compare
BWI76_RS12070 -1.4 -1.1 hypothetical protein compare
BWI76_RS25315 -1.3 -8.5 glutamate synthase large subunit compare
BWI76_RS11820 -1.3 -1.5 short-chain dehydrogenase/reductase SDR compare
BWI76_RS15830 -1.3 -2.8 hypothetical protein compare
BWI76_RS19325 -1.3 -2.0 mandelate racemase compare
BWI76_RS00390 -1.3 -3.9 two-component system sensor histidine kinase NtrB compare
BWI76_RS22695 -1.2 -4.5 sulfate adenylyltransferase compare
BWI76_RS02990 -1.2 -3.8 aspartate carbamoyltransferase regulatory subunit compare
BWI76_RS20510 -1.2 -4.2 glucokinase compare
BWI76_RS26075 -1.2 -3.6 DNA adenine methylase compare
BWI76_RS23020 -1.2 -1.8 cobalamin biosynthesis protein CbiQ compare
BWI76_RS18605 -1.2 -1.5 oxidoreductase molybdopterin-binding protein compare
BWI76_RS18770 -1.2 -0.9 DNA gyrase inhibitor compare
BWI76_RS20785 -1.1 -1.2 ethanolamine utilization protein EutJ compare
BWI76_RS09150 -1.1 -3.2 DNA-binding transcriptional repressor DeoR compare
BWI76_RS07780 -1.1 -1.5 hypothetical protein compare
BWI76_RS17375 -1.1 -1.9 nitrate ABC transporter, permease protein compare
BWI76_RS06485 -1.1 -2.4 cytochrome o ubiquinol oxidase subunit III compare
BWI76_RS03105 -1.1 -1.1 myo-inosose-2 dehydratase compare
BWI76_RS12090 -1.1 -2.4 HNH endonuclease compare
BWI76_RS22700 -1.1 -3.8 sulfate adenylyltransferase subunit 2 compare
BWI76_RS21140 -1.0 -2.6 molecular chaperone HscA compare
BWI76_RS24900 -1.0 -1.8 DeoR family transcriptional regulator compare
BWI76_RS13070 -1.0 -2.3 hypothetical protein compare
BWI76_RS09530 -1.0 -1.1 hypothetical protein compare
BWI76_RS24075 -1.0 -3.1 glutathione synthase compare
BWI76_RS06530 -1.0 -3.1 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS04525 -1.0 -1.9 4-hydroxythreonine-4-phosphate dehydrogenase PdxA compare
BWI76_RS14065 -1.0 -1.6 hypothetical protein compare
BWI76_RS19375 -1.0 -1.5 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase compare
BWI76_RS23885 -1.0 -1.7 2-octaprenylphenol hydroxylase compare
BWI76_RS17675 -1.0 -1.7 hypothetical protein compare
BWI76_RS01200 -1.0 -1.5 diaminopimelate epimerase compare
BWI76_RS08315 -1.0 -1.7 K+-transporting ATPase subunit B compare
BWI76_RS02985 -1.0 -4.4 reactive intermediate/imine deaminase compare
BWI76_RS09635 -1.0 -1.3 amino acid ABC transporter ATP-binding protein compare
BWI76_RS15835 -1.0 -0.6 hypothetical protein compare
BWI76_RS22120 -1.0 -3.3 glutamate--cysteine ligase compare
BWI76_RS10330 -0.9 -1.6 TetR family transcriptional regulator compare
BWI76_RS07380 -0.9 -2.1 hypothetical protein compare
BWI76_RS18675 -0.9 -2.2 fimbrial protein compare
BWI76_RS21505 -0.9 -1.1 hypothetical protein compare
BWI76_RS24385 -0.9 -5.1 phosphodiesterase compare
BWI76_RS11435 -0.9 -1.3 hypothetical protein compare
BWI76_RS15840 -0.9 -2.2 prophage protein compare
BWI76_RS13320 -0.9 -1.9 putative LpxA-like enzyme compare
BWI76_RS20000 -0.9 -1.6 competence/damage-inducible protein A compare
BWI76_RS27310 -0.9 -4.5 glycosyltransferase compare
BWI76_RS12895 -0.9 -1.9 hypothetical protein compare
BWI76_RS17155 -0.9 -1.2 hypothetical protein compare
BWI76_RS07160 -0.9 -2.1 MBL fold hydrolase compare
BWI76_RS18430 -0.9 -2.9 hypothetical protein compare
BWI76_RS10245 -0.9 -2.3 aspartate aminotransferase compare
BWI76_RS15850 -0.9 -1.0 DUF1317 domain-containing protein compare
BWI76_RS14435 -0.9 -1.2 glutamine ABC transporter ATP-binding protein compare
BWI76_RS06295 -0.9 -4.3 S-adenosylmethionine:tRNA ribosyltransferase-isomerase compare
BWI76_RS15650 -0.9 -2.4 gp5 compare
BWI76_RS00940 -0.9 -4.2 transcriptional regulator HdfR compare
BWI76_RS01275 -0.9 -2.9 LysR family transcriptional regulator compare
BWI76_RS04570 -0.9 -3.5 RNA polymerase-associated protein RapA compare
BWI76_RS15980 -0.8 -1.6 lysine transporter LysE compare
BWI76_RS20970 -0.8 -1.3 phosphoribosylglycinamide formyltransferase compare
BWI76_RS21580 -0.8 -1.1 SsrA-binding protein compare
BWI76_RS07640 -0.8 -1.3 short chain dehydrogenase compare
BWI76_RS04530 -0.8 -1.4 peptidylprolyl isomerase SurA compare
BWI76_RS05880 -0.8 -1.9 AraC-type DNA-binding domain-containing protein compare
BWI76_RS21560 -0.8 -2.2 DNA repair protein RecN compare
BWI76_RS22475 -0.8 -2.2 heme ABC transporter ATP-binding protein compare
BWI76_RS01385 -0.8 -1.2 potassium transporter compare


Specific Phenotypes

For 7 genes in this experiment

For carbon source D-Maltose monohydrate in Klebsiella michiganensis M5al

For carbon source D-Maltose monohydrate across organisms