Experiment set5IT031 for Methanococcus maripaludis S2

Compare to:

Formate with cyanide 50 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS03315 -4.7 -2.8 ferrous iron transport protein A compare
MMP_RS01175 -3.6 -8.5 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS06700 -3.6 -24.2 hypothetical protein compare
MMP_RS06680 -3.3 -19.6 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS00300 -3.2 -1.7 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS06685 -3.1 -14.7 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS08820 -2.9 -10.1 hypothetical protein compare
MMP_RS01020 -2.8 -2.8 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS01005 -2.7 -2.7 riboflavin synthase compare
MMP_RS07575 -2.7 -7.6 RNA ligase partner protein compare
MMP_RS06345 -2.5 -13.2 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS01265 -2.4 -3.0 hypothetical protein compare
MMP_RS00895 -2.4 -7.3 hypothetical protein compare
MMP_RS04780 -2.3 -5.0 ribonuclease P compare
MMP_RS06400 -2.3 -3.8 4Fe-4S binding protein compare
MMP_RS00115 -2.3 -15.9 radical SAM protein compare
MMP_RS01225 -2.3 -7.6 DUF5379 domain-containing protein compare
MMP_RS01755 -2.2 -2.9 DUF2097 domain-containing protein compare
MMP_RS02010 -2.2 -11.5 PHP domain-containing protein compare
MMP_RS07380 -2.2 -5.4 transcription elongation factor Spt5 compare
MMP_RS07845 -2.1 -5.7 LL-diaminopimelate aminotransferase compare
MMP_RS06295 -2.1 -9.9 methanogenesis marker 14 protein compare
MMP_RS07635 -2.1 -8.7 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS03015 -2.1 -15.4 GTP 3' 8-cyclase MoaA compare
MMP_RS06730 -2.1 -3.3 phosphopantothenate/pantothenate synthetase compare
MMP_RS05515 -2.0 -8.3 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS06715 -2.0 -14.5 cache domain-containing protein compare
MMP_RS08745 -2.0 -9.7 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS06355 -2.0 -5.0 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS08720 -1.9 -1.7 4Fe-4S binding protein compare
MMP_RS06720 -1.9 -12.6 response regulator transcription factor compare
MMP_RS06105 -1.9 -9.4 hydrogenase maturation peptidase HycI compare
MMP_RS06350 -1.9 -6.4 HesA/MoeB/ThiF family protein compare
MMP_RS08300 -1.8 -2.4 metal-sulfur cluster assembly factor compare
MMP_RS01220 -1.8 -11.9 hypothetical protein compare
MMP_RS08460 -1.8 -4.2 proteasome-activating nucleotidase compare
MMP_RS04685 -1.8 -4.8 DUF126 domain-containing protein compare
MMP_RS01500 -1.8 -3.4 CBS domain-containing protein compare
MMP_RS02280 -1.8 -2.1 DUF211 domain-containing protein compare
MMP_RS08210 -1.8 -3.1 phosphatidylglycerophosphatase A compare
MMP_RS06705 -1.7 -7.4 formate/nitrite transporter family protein compare
MMP_RS03600 -1.7 -4.0 triose-phosphate isomerase compare
MMP_RS00305 -1.7 -2.8 phosphoribosyl-ATP diphosphatase compare
MMP_RS02195 -1.7 -6.7 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS03025 -1.7 -9.3 molybdenum cofactor guanylyltransferase compare
MMP_RS02900 -1.6 -1.1 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS04775 -1.6 -5.2 adenosylhomocysteinase compare
MMP_RS03400 -1.6 -4.0 archease compare
MMP_RS05245 -1.6 -10.7 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS07445 -1.5 -6.9 helix-turn-helix domain-containing protein compare
MMP_RS00695 -1.5 -1.2 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS06625 -1.5 -2.4 DNA primase compare
MMP_RS07545 -1.5 -2.6 HTH domain-containing protein compare
MMP_RS08715 -1.5 -3.3 formylmethanofuran dehydrogenase subunit B compare
MMP_RS00685 -1.5 -5.7 2-phospho-L-lactate guanylyltransferase compare
MMP_RS02355 -1.4 -5.1 30S ribosomal protein S27ae compare
MMP_RS08200 -1.4 -11.8 archaeosine synthase subunit alpha compare
MMP_RS00295 -1.4 -2.9 gamma carbonic anhydrase family protein compare
MMP_RS02135 -1.4 -4.4 DUF5612 domain-containing protein compare
MMP_RS04890 -1.4 -1.2 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS06630 -1.4 -1.6 UPF0058 family protein compare
MMP_RS07730 -1.3 -2.5 pyruvate synthase subunit beta compare
MMP_RS00110 -1.3 -4.2 hypothetical protein compare
MMP_RS03445 -1.3 -1.9 methanogenesis marker 17 protein compare
MMP_RS07525 -1.3 -7.8 4Fe-4S binding protein compare
MMP_RS06230 -1.3 -3.2 helix-turn-helix domain-containing protein compare
MMP_RS06020 -1.3 -5.1 archaeoflavoprotein AfpA compare
MMP_RS09020 -1.3 -2.7 hypothetical protein compare
MMP_RS07600 -1.3 -3.1 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS05875 -1.3 -4.2 hydroxyethylthiazole kinase compare
MMP_RS06340 -1.3 -7.8 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS02235 -1.3 -8.7 CBS domain-containing protein compare
MMP_RS06285 -1.3 -3.4 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS06270 -1.3 -4.4 TIGR00300 family protein compare
MMP_RS03580 -1.2 -3.7 signal recognition particle-docking protein FtsY compare
MMP_RS01365 -1.2 -3.8 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS02240 -1.2 -3.0 methanogenesis marker 7 protein compare
MMP_RS01250 -1.2 -5.9 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS05550 -1.2 -1.3 cation:proton antiporter compare
MMP_RS04585 -1.1 -6.7 AIR synthase related protein compare
MMP_RS03640 -1.1 -4.2 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS02165 -1.1 -9.1 tRNA-dihydrouridine synthase compare
MMP_RS06110 -1.1 -4.6 ATP-dependent protease LonB compare
MMP_RS05430 -1.1 -5.4 TIGR00288 family NYN domain-containing protein compare
MMP_RS00515 -1.1 -1.5 DUF655 domain-containing protein compare
MMP_RS02800 -1.1 -5.0 nucleotidyltransferase domain-containing protein compare
MMP_RS07765 -1.0 -6.4 sodium:alanine symporter family protein compare
MMP_RS02145 -1.0 -5.8 winged helix-turn-helix transcriptional regulator compare
MMP_RS07005 -1.0 -0.9 4Fe-4S binding protein compare
MMP_RS01720 -1.0 -1.0 replication factor C large subunit compare
MMP_RS07735 -1.0 -1.5 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS08635 -1.0 -1.9 UbiA family prenyltransferase compare
MMP_RS01985 -1.0 -4.2 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS08645 -1.0 -5.8 UPF0179 family protein compare
MMP_RS07755 -1.0 -1.7 DUF555 domain-containing protein compare
MMP_RS02190 -0.9 -2.6 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS01325 -0.9 -2.6 dihydroneopterin aldolase family protein compare
MMP_RS03470 -0.9 -7.4 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS03960 -0.9 -1.1 hypothetical protein compare
MMP_RS07200 -0.9 -4.7 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS05920 -0.9 -1.0 50S ribosomal protein L37e compare
MMP_RS07365 -0.9 -7.2 2-phosphoglycerate kinase compare
MMP_RS05540 -0.9 -2.8 hypothetical protein compare
MMP_RS04955 -0.9 -3.8 DNA topoisomerase I compare
MMP_RS05815 -0.9 -2.4 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS01980 -0.9 -7.3 trimeric intracellular cation channel family protein compare
MMP_RS04710 -0.9 -1.8 hypothetical protein compare
MMP_RS07580 -0.9 -2.9 DUF356 domain-containing protein compare
MMP_RS07385 -0.9 -1.4 protein translocase SEC61 complex subunit gamma compare
MMP_RS00620 -0.9 -4.8 4Fe-4S binding protein compare
MMP_RS03435 -0.9 -1.7 ketol-acid reductoisomerase compare
MMP_RS08650 -0.8 -2.3 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS01610 -0.8 -2.8 hypothetical protein compare
MMP_RS03155 -0.8 -5.2 precorrin-6A reductase compare
MMP_RS02345 -0.8 -2.4 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS06940 -0.8 -2.6 polyprenyl diphosphate synthase compare
MMP_RS03035 -0.8 -2.4 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS04605 -0.8 -4.6 cobalt ECF transporter T component CbiQ compare
MMP_RS01800 -0.8 -3.0 TIGR00303 family protein compare
MMP_RS05765 -0.8 -3.5 M42 family metallopeptidase compare
MMP_RS06475 -0.7 -2.8 FAD-dependent oxidoreductase compare
MMP_RS01795 -0.7 -2.0 methanogenesis marker 6 protein compare
MMP_RS03555 -0.7 -4.1 transcriptional regulator compare
MMP_RS01240 -0.7 -0.8 7-cyano-7-deazaguanine synthase QueC compare
MMP_RS05445 -0.7 -4.5 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS07630 -0.7 -1.9 ATP-binding cassette domain-containing protein compare
MMP_RS06895 -0.7 -1.9 selenocysteine-specific translation elongation factor compare
MMP_RS03210 -0.7 -5.9 tRNA guanosine(15) transglycosylase TgtA compare
MMP_RS08165 -0.7 -1.4 phosphoglycerate dehydrogenase compare
MMP_RS07390 -0.7 -1.9 cell division protein FtsZ compare
MMP_RS06975 -0.7 -2.1 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS06925 -0.7 -1.8 ribonuclease VapC4 compare
MMP_RS08320 -0.7 -4.2 molybdopterin molybdotransferase MoeA compare
MMP_RS08790 -0.7 -0.9 translation initiation factor IF-2 subunit alpha compare
MMP_RS00915 -0.7 -4.2 DUF116 domain-containing protein compare
MMP_RS01380 -0.7 -2.6 PHP domain-containing protein compare
MMP_RS05510 -0.6 -4.9 Rrf2 family transcriptional regulator compare
MMP_RS02245 -0.6 -2.4 hypothetical protein compare
MMP_RS07625 -0.6 -2.1 cobalt ECF transporter T component CbiQ compare
MMP_RS06885 -0.6 -2.3 50S ribosome-binding GTPase compare
MMP_RS06855 -0.6 -4.0 hypothetical protein compare
MMP_RS01955 -0.6 -2.4 hypothetical protein compare
MMP_RS06310 -0.6 -2.9 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS08725 -0.6 -2.3 Ni/Fe hydrogenase subunit alpha compare
MMP_RS06315 -0.6 -0.9 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS00290 -0.6 -3.4 hypothetical protein compare
MMP_RS00810 -0.6 -3.3 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS05545 -0.6 -2.5 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS07075 -0.6 -2.4 phosphomannomutase/phosphoglucomutase compare
MMP_RS01890 -0.6 -2.0 nucleotide sugar dehydrogenase compare
MMP_RS08915 -0.6 -1.2 2 5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase compare
MMP_RS06200 -0.6 -4.1 M24 family metallopeptidase compare
MMP_RS07605 -0.6 -1.2 diadenylate cyclase compare
MMP_RS00520 -0.6 -0.8 RNA polymerase Rpb4 family protein compare
MMP_RS00345 -0.6 -3.1 DUF2666 domain-containing protein compare
MMP_RS08435 -0.6 -1.7 Era-like GTP-binding protein compare
MMP_RS07425 -0.6 -2.3 GTP-binding protein compare
MMP_RS06865 -0.6 -1.7 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS08290 -0.6 -4.5 DNA-binding protein Alba compare
MMP_RS02130 -0.5 -2.0 zinc metalloprotease HtpX compare
MMP_RS05250 -0.5 -1.1 NFYB/HAP3 family transcription factor subunit compare
MMP_RS05845 -0.5 -1.3 tRNA-intron lyase compare
MMP_RS00985 -0.5 -2.5 CDC48 family AAA ATPase compare
MMP_RS01100 -0.5 -1.3 ABC transporter ATP-binding protein compare
MMP_RS02885 -0.5 -4.4 molybdopterin biosynthesis protein compare
MMP_RS01830 -0.5 -0.9 tRNA-Val compare
MMP_RS01725 -0.5 -2.1 class I SAM-dependent methyltransferase family protein compare
MMP_RS02875 -0.5 -3.1 chorismate pyruvate-lyase family protein compare
MMP_RS04305 -0.5 -2.0 hypothetical protein compare
MMP_RS00080 -0.5 -3.3 RecB-family nuclease compare
MMP_RS07750 -0.5 -1.4 DUF357 domain-containing protein compare
MMP_RS07710 -0.5 -2.7 cell division protein FtsZ compare
MMP_RS07190 -0.5 -2.7 chromosome segregation protein SMC compare
MMP_RS05555 -0.5 -1.1 DUF4040 domain-containing protein compare
MMP_RS05265 -0.5 -1.1 2-isopropylmalate synthase compare
MMP_RS07420 -0.5 -2.2 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS06770 -0.4 -3.4 DHH family phosphoesterase compare
MMP_RS00060 -0.4 -1.4 3-dehydroquinate synthase II compare
MMP_RS06120 -0.4 -1.3 UPF0147 family protein compare
MMP_RS00430 -0.4 -3.0 hypothetical protein compare
MMP_RS07535 -0.4 -2.9 4Fe-4S binding protein compare
MMP_RS02265 -0.4 -2.5 nitroreductase family protein compare
MMP_RS01195 -0.4 -1.0 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS03095 -0.4 -2.3 diphthine synthase compare
MMP_RS03685 -0.4 -3.1 Mrp/NBP35 family ATP-binding protein compare
MMP_RS00720 -0.4 -3.1 metal-dependent hydrolase compare
MMP_RS04500 -0.4 -3.4 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS00050 -0.4 -2.3 AarF/UbiB family protein compare
MMP_RS03440 -0.4 -0.9 MoaD/ThiS family protein compare
MMP_RS07350 -0.4 -1.1 preprotein translocase subunit Sec61beta compare
MMP_RS01780 -0.4 -2.6 TrmJ/YjtD family RNA methyltransferase compare
MMP_RS04615 -0.4 -1.6 PDGLE domain-containing protein compare
MMP_RS07775 -0.4 -2.6 alanine dehydrogenase compare
MMP_RS04620 -0.4 -2.9 cobalt transporter CbiM compare
MMP_RS01840 -0.4 -2.4 TIGR00289 family protein compare
MMP_RS01910 -0.4 -2.9 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS06215 -0.4 -1.4 30S ribosomal protein S6e compare
MMP_RS01970 -0.4 -3.1 TIGR04279 domain-containing protein compare
MMP_RS01385 -0.4 -0.4 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS01045 -0.4 -2.3 diphthamide biosynthesis enzyme Dph2 compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Sodium cyanide across organisms