Experiment set5IT030 for Methanococcus maripaludis S2

Compare to:

Formate with ticarcillin 50 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS00735 -3.4 -8.5 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS00730 -3.4 -12.9 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS03315 -3.3 -2.0 ferrous iron transport protein A compare
MMP_RS00725 -3.1 -14.0 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS07695 -3.0 -9.3 DUF3236 domain-containing protein compare
MMP_RS04850 -2.9 -23.6 UPF0254 family protein compare
MMP_RS01175 -2.8 -9.7 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS07700 -2.7 -14.3 DUF1188 domain-containing protein compare
MMP_RS06700 -2.7 -16.2 hypothetical protein compare
MMP_RS06395 -2.4 -5.9 ThiF family adenylyltransferase compare
MMP_RS06355 -2.4 -5.7 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS01265 -2.4 -6.4 hypothetical protein compare
MMP_RS01755 -2.3 -2.8 DUF2097 domain-containing protein compare
MMP_RS05515 -2.3 -14.3 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS06685 -2.2 -15.8 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS08820 -2.1 -6.4 hypothetical protein compare
MMP_RS06680 -2.1 -15.5 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS01020 -2.1 -2.5 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS07635 -2.0 -7.6 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS08300 -2.0 -2.9 metal-sulfur cluster assembly factor compare
MMP_RS08720 -2.0 -3.2 4Fe-4S binding protein compare
MMP_RS01500 -2.0 -4.0 CBS domain-containing protein compare
MMP_RS07845 -1.9 -4.9 LL-diaminopimelate aminotransferase compare
MMP_RS06350 -1.9 -8.5 HesA/MoeB/ThiF family protein compare
MMP_RS00315 -1.8 -10.1 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS08635 -1.8 -3.9 UbiA family prenyltransferase compare
MMP_RS03015 -1.8 -11.2 GTP 3' 8-cyclase MoaA compare
MMP_RS06295 -1.8 -9.2 methanogenesis marker 14 protein compare
MMP_RS02280 -1.8 -2.0 DUF211 domain-containing protein compare
MMP_RS07575 -1.8 -4.6 RNA ligase partner protein compare
MMP_RS00115 -1.8 -12.8 radical SAM protein compare
MMP_RS06345 -1.7 -11.5 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS04585 -1.7 -10.0 AIR synthase related protein compare
MMP_RS03600 -1.7 -4.1 triose-phosphate isomerase compare
MMP_RS02010 -1.7 -10.1 PHP domain-containing protein compare
MMP_RS02145 -1.7 -7.4 winged helix-turn-helix transcriptional regulator compare
MMP_RS00895 -1.7 -5.0 hypothetical protein compare
MMP_RS03445 -1.7 -2.1 methanogenesis marker 17 protein compare
MMP_RS00300 -1.6 -1.3 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS04685 -1.6 -5.2 DUF126 domain-containing protein compare
MMP_RS08745 -1.6 -7.2 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS00305 -1.6 -2.8 phosphoribosyl-ATP diphosphatase compare
MMP_RS06400 -1.6 -2.7 4Fe-4S binding protein compare
MMP_RS00515 -1.6 -1.5 DUF655 domain-containing protein compare
MMP_RS01225 -1.5 -5.1 DUF5379 domain-containing protein compare
MMP_RS01005 -1.5 -2.8 riboflavin synthase compare
MMP_RS02195 -1.5 -7.1 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS08460 -1.5 -4.3 proteasome-activating nucleotidase compare
MMP_RS05430 -1.5 -4.8 TIGR00288 family NYN domain-containing protein compare
MMP_RS08650 -1.4 -3.1 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS06720 -1.4 -7.9 response regulator transcription factor compare
MMP_RS07380 -1.4 -3.8 transcription elongation factor Spt5 compare
MMP_RS08210 -1.4 -3.5 phosphatidylglycerophosphatase A compare
MMP_RS06715 -1.4 -10.6 cache domain-containing protein compare
MMP_RS03960 -1.4 -1.4 hypothetical protein compare
MMP_RS06285 -1.4 -3.6 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS05245 -1.4 -9.6 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS02240 -1.3 -4.0 methanogenesis marker 7 protein compare
MMP_RS04890 -1.3 -1.4 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS08715 -1.3 -1.8 formylmethanofuran dehydrogenase subunit B compare
MMP_RS07445 -1.3 -6.0 helix-turn-helix domain-containing protein compare
MMP_RS07005 -1.3 -1.0 4Fe-4S binding protein compare
MMP_RS01325 -1.3 -2.6 dihydroneopterin aldolase family protein compare
MMP_RS03025 -1.2 -7.0 molybdenum cofactor guanylyltransferase compare
MMP_RS06270 -1.2 -3.4 TIGR00300 family protein compare
MMP_RS00295 -1.2 -3.3 gamma carbonic anhydrase family protein compare
MMP_RS01220 -1.2 -5.7 hypothetical protein compare
MMP_RS07200 -1.2 -5.4 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS05920 -1.2 -1.2 50S ribosomal protein L37e compare
MMP_RS04775 -1.2 -3.2 adenosylhomocysteinase compare
MMP_RS06230 -1.1 -2.6 helix-turn-helix domain-containing protein compare
MMP_RS02800 -1.1 -6.6 nucleotidyltransferase domain-containing protein compare
MMP_RS07525 -1.1 -7.3 4Fe-4S binding protein compare
MMP_RS06730 -1.1 -2.8 phosphopantothenate/pantothenate synthetase compare
MMP_RS05540 -1.1 -3.9 hypothetical protein compare
MMP_RS02235 -1.1 -7.6 CBS domain-containing protein compare
MMP_RS08200 -1.1 -8.1 archaeosine synthase subunit alpha compare
MMP_RS06020 -1.0 -4.8 archaeoflavoprotein AfpA compare
MMP_RS01610 -1.0 -4.3 hypothetical protein compare
MMP_RS06340 -1.0 -5.5 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS06705 -1.0 -5.0 formate/nitrite transporter family protein compare
MMP_RS04780 -1.0 -2.2 ribonuclease P compare
MMP_RS07545 -1.0 -1.9 HTH domain-containing protein compare
MMP_RS06475 -1.0 -4.3 FAD-dependent oxidoreductase compare
MMP_RS05875 -1.0 -3.0 hydroxyethylthiazole kinase compare
MMP_RS08435 -0.9 -2.8 Era-like GTP-binding protein compare
MMP_RS01365 -0.9 -4.3 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS06110 -0.9 -2.6 ATP-dependent protease LonB compare
MMP_RS06865 -0.9 -2.0 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS07630 -0.9 -1.6 ATP-binding cassette domain-containing protein compare
MMP_RS00110 -0.9 -3.3 hypothetical protein compare
MMP_RS06625 -0.8 -1.8 DNA primase compare
MMP_RS03385 -0.8 -1.4 cation diffusion facilitator family transporter compare
MMP_RS00695 -0.8 -1.2 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS05555 -0.8 -1.4 DUF4040 domain-containing protein compare
MMP_RS03435 -0.8 -1.8 ketol-acid reductoisomerase compare
MMP_RS07625 -0.8 -3.2 cobalt ECF transporter T component CbiQ compare
MMP_RS00685 -0.8 -2.9 2-phospho-L-lactate guanylyltransferase compare
MMP_RS04955 -0.8 -3.3 DNA topoisomerase I compare
MMP_RS03470 -0.8 -4.6 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS07755 -0.8 -1.5 DUF555 domain-containing protein compare
MMP_RS08165 -0.8 -1.5 phosphoglycerate dehydrogenase compare
MMP_RS07730 -0.8 -1.8 pyruvate synthase subunit beta compare
MMP_RS07075 -0.8 -4.2 phosphomannomutase/phosphoglucomutase compare
MMP_RS00720 -0.7 -5.0 metal-dependent hydrolase compare
MMP_RS08725 -0.7 -2.5 Ni/Fe hydrogenase subunit alpha compare
MMP_RS02230 -0.7 -4.9 sodium-dependent transporter compare
MMP_RS01890 -0.7 -3.6 nucleotide sugar dehydrogenase compare
MMP_RS07600 -0.7 -2.5 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS03640 -0.7 -2.8 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS05250 -0.7 -1.3 NFYB/HAP3 family transcription factor subunit compare
MMP_RS00620 -0.7 -4.6 4Fe-4S binding protein compare
MMP_RS09020 -0.7 -1.3 hypothetical protein compare
MMP_RS08320 -0.7 -4.0 molybdopterin molybdotransferase MoeA compare
MMP_RS06770 -0.7 -5.3 DHH family phosphoesterase compare
MMP_RS02190 -0.7 -2.4 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS03300 -0.7 -1.1 TOBE domain-containing protein compare
MMP_RS00675 -0.7 -1.3 nitroreductase family protein compare
MMP_RS02885 -0.7 -5.6 molybdopterin biosynthesis protein compare
MMP_RS00060 -0.7 -1.4 3-dehydroquinate synthase II compare
MMP_RS01795 -0.7 -1.6 methanogenesis marker 6 protein compare
MMP_RS07615 -0.7 -5.0 energy-coupling factor ABC transporter permease compare
MMP_RS02135 -0.7 -2.3 DUF5612 domain-containing protein compare
MMP_RS02245 -0.6 -2.5 hypothetical protein compare
MMP_RS02355 -0.6 -2.5 30S ribosomal protein S27ae compare
MMP_RS06630 -0.6 -1.0 UPF0058 family protein compare
MMP_RS07765 -0.6 -4.5 sodium:alanine symporter family protein compare
MMP_RS08240 -0.6 -3.6 methanogenesis marker 16 metalloprotein compare
MMP_RS01665 -0.6 -3.1 DUF2111 domain-containing protein compare
MMP_RS08350 -0.6 -1.0 hypothetical protein compare
MMP_RS06105 -0.6 -3.7 hydrogenase maturation peptidase HycI compare
MMP_RS08195 -0.6 -4.6 hypothetical protein compare
MMP_RS03205 -0.6 -1.0 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS04720 -0.6 -1.5 DedA family protein compare
MMP_RS00520 -0.6 -1.4 RNA polymerase Rpb4 family protein compare
MMP_RS04695 -0.6 -4.1 selenide water dikinase SelD compare
MMP_RS03210 -0.6 -4.9 tRNA guanosine(15) transglycosylase TgtA compare
MMP_RS03700 -0.6 -3.3 sodium:proton antiporter compare
MMP_RS03580 -0.5 -1.8 signal recognition particle-docking protein FtsY compare
MMP_RS03250 -0.5 -2.2 MJ1244 family protein compare
MMP_RS01240 -0.5 -1.1 7-cyano-7-deazaguanine synthase QueC compare
MMP_RS01800 -0.5 -2.7 TIGR00303 family protein compare
MMP_RS05445 -0.5 -3.8 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS07390 -0.5 -1.0 cell division protein FtsZ compare
MMP_RS02875 -0.5 -3.1 chorismate pyruvate-lyase family protein compare
MMP_RS01900 -0.5 -4.3 hypothetical protein compare
MMP_RS06525 -0.5 -1.2 YciI family protein compare
MMP_RS06175 -0.5 -3.8 winged helix-turn-helix transcriptional regulator compare
MMP_RS02130 -0.5 -2.2 zinc metalloprotease HtpX compare
MMP_RS03035 -0.5 -1.4 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS01905 -0.5 -4.3 glycosyltransferase compare
MMP_RS01370 -0.5 -3.8 acetate--CoA ligase family protein compare
MMP_RS06120 -0.5 -1.3 UPF0147 family protein compare
MMP_RS02900 -0.5 -0.4 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS06940 -0.5 -1.7 polyprenyl diphosphate synthase compare
MMP_RS06925 -0.5 -1.3 ribonuclease VapC4 compare
MMP_RS00915 -0.5 -3.2 DUF116 domain-containing protein compare
MMP_RS08915 -0.5 -1.1 2 5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase compare
MMP_RS05815 -0.5 -1.4 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS02410 -0.5 -1.5 ABC transporter substrate-binding protein compare
MMP_RS03155 -0.5 -3.0 precorrin-6A reductase compare
MMP_RS06310 -0.5 -2.6 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS01180 -0.5 -1.0 XTP/dITP diphosphatase compare
MMP_RS03555 -0.5 -3.4 transcriptional regulator compare
MMP_RS04870 -0.5 -2.3 TIGR02253 family HAD-type hydrolase compare
MMP_RS05510 -0.4 -3.1 Rrf2 family transcriptional regulator compare
MMP_RS01720 -0.4 -1.4 replication factor C large subunit compare
MMP_RS01250 -0.4 -2.2 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS02165 -0.4 -2.3 tRNA-dihydrouridine synthase compare
MMP_RS03485 -0.4 -2.2 TIGR00267 family protein compare
MMP_RS08440 -0.4 -1.4 cell division protein SepF compare
MMP_RS05355 -0.4 -0.7 hypothetical protein compare
MMP_RS00120 -0.4 -2.2 LysR family transcriptional regulator compare
MMP_RS06895 -0.4 -1.0 selenocysteine-specific translation elongation factor compare
MMP_RS00760 -0.4 -3.0 branched-chain-amino-acid transaminase compare
MMP_RS03020 -0.4 -2.9 peptidylprolyl isomerase compare
MMP_RS00810 -0.4 -2.3 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS05065 -0.4 -1.8 CooT family nickel-binding protein compare
MMP_RS05965 -0.4 -1.7 carboxymuconolactone decarboxylase family protein compare
MMP_RS04605 -0.4 -2.4 cobalt ECF transporter T component CbiQ compare
MMP_RS03685 -0.4 -2.8 Mrp/NBP35 family ATP-binding protein compare
MMP_RS00345 -0.4 -2.5 DUF2666 domain-containing protein compare
MMP_RS07685 -0.4 -2.1 TIGR01212 family radical SAM protein compare
MMP_RS03400 -0.4 -1.5 archease compare
MMP_RS06315 -0.4 -0.6 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS08290 -0.4 -2.8 DNA-binding protein Alba compare
MMP_RS05550 -0.4 -0.5 cation:proton antiporter compare
MMP_RS05700 -0.4 -2.6 TfuA-related McrA-glycine thioamidation protein compare
MMP_RS01895 -0.4 -3.1 flippase compare
MMP_RS05765 -0.4 -2.7 M42 family metallopeptidase compare
MMP_RS01380 -0.3 -1.7 PHP domain-containing protein compare
MMP_RS07735 -0.3 -0.6 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS05315 -0.3 -1.1 hypothetical protein compare
MMP_RS03305 -0.3 -2.6 winged helix-turn-helix domain-containing protein compare
MMP_RS05440 -0.3 -2.1 winged helix-turn-helix transcriptional regulator compare
MMP_RS03590 -0.3 -1.5 METTL5 family protein compare
MMP_RS06485 -0.3 -0.6 zinc ribbon domain-containing protein compare
MMP_RS01940 -0.3 -1.3 MoxR family ATPase compare
MMP_RS00290 -0.3 -1.7 hypothetical protein compare
MMP_RS05975 -0.3 -0.9 hypothetical protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Ticarcillin disodium salt across organisms