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Experiment set5IT027 for
Methanococcus maripaludis S2
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Formate McCas no stress control 1
200 most important genes:
gene
name
fitness
t score
description
MMP
_RS06700
-4.0
-20.9
hypothetical protein
compare
MMP
_RS01175
-3.5
-9.3
triphosphoribosyl-dephospho-CoA synthase
compare
MMP
_RS01020
-3.4
-2.7
3 4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMP
_RS06355
-3.4
-6.3
molybdenum cofactor biosynthesis protein MoaE
compare
MMP
_RS03475
-3.4
-1.4
hypothetical protein
compare
MMP
_RS06685
-3.2
-17.5
formate dehydrogenase H subunit alpha selenocysteine-containing
compare
MMP
_RS06680
-3.2
-21.1
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
compare
MMP
_RS05515
-3.0
-13.7
cyclic pyranopterin monophosphate synthase MoaC
compare
MMP
_RS05920
-3.0
-1.8
50S ribosomal protein L37e
compare
MMP
_RS07635
-2.9
-9.4
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMP
_RS05550
-2.8
-1.9
cation:proton antiporter
compare
MMP
_RS06345
-2.8
-17.9
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMP
_RS08820
-2.7
-7.5
hypothetical protein
compare
MMP
_RS03015
-2.7
-14.3
GTP 3' 8-cyclase MoaA
compare
MMP
_RS06350
-2.6
-10.9
HesA/MoeB/ThiF family protein
compare
MMP
_RS06715
-2.5
-18.9
cache domain-containing protein
compare
MMP
_RS06720
-2.5
-11.4
response regulator transcription factor
compare
MMP
_RS03600
-2.5
-3.4
triose-phosphate isomerase
compare
MMP
_RS02010
-2.5
-10.7
PHP domain-containing protein
compare
MMP
_RS08720
-2.5
-3.8
4Fe-4S binding protein
compare
MMP
_RS01005
-2.4
-2.3
riboflavin synthase
compare
MMP
_RS01265
-2.3
-3.9
hypothetical protein
compare
MMP
_RS07845
-2.2
-5.9
LL-diaminopimelate aminotransferase
compare
MMP
_RS00895
-2.2
-6.4
hypothetical protein
compare
MMP
_RS01755
-2.1
-2.6
DUF2097 domain-containing protein
compare
MMP
_RS07600
-2.1
-5.0
Ni-sirohydrochlorin a c-diamide synthase
compare
MMP
_RS01500
-2.1
-4.8
CBS domain-containing protein
compare
MMP
_RS07445
-2.0
-6.9
helix-turn-helix domain-containing protein
compare
MMP
_RS07575
-2.0
-8.2
RNA ligase partner protein
compare
MMP
_RS06705
-2.0
-7.6
formate/nitrite transporter family protein
compare
MMP
_RS05555
-2.0
-2.3
DUF4040 domain-containing protein
compare
MMP
_RS03315
-2.0
-1.4
ferrous iron transport protein A
compare
MMP
_RS03025
-2.0
-9.3
molybdenum cofactor guanylyltransferase
compare
MMP
_RS06400
-2.0
-3.8
4Fe-4S binding protein
compare
MMP
_RS04780
-1.9
-5.0
ribonuclease P
compare
MMP
_RS06295
-1.9
-10.2
methanogenesis marker 14 protein
compare
MMP
_RS02800
-1.9
-7.3
nucleotidyltransferase domain-containing protein
compare
MMP
_RS08745
-1.9
-8.8
CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMP
_RS00115
-1.9
-16.0
radical SAM protein
compare
MMP
_RS02195
-1.9
-7.3
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
compare
MMP
_RS02355
-1.9
-5.3
30S ribosomal protein S27ae
compare
MMP
_RS00295
-1.8
-5.2
gamma carbonic anhydrase family protein
compare
MMP
_RS02280
-1.8
-2.1
DUF211 domain-containing protein
compare
MMP
_RS08210
-1.8
-3.3
phosphatidylglycerophosphatase A
compare
MMP
_RS00300
-1.8
-1.4
6 7-dimethyl-8-ribityllumazine synthase
compare
MMP
_RS02240
-1.8
-4.5
methanogenesis marker 7 protein
compare
MMP
_RS08460
-1.8
-3.6
proteasome-activating nucleotidase
compare
MMP
_RS04775
-1.8
-4.4
adenosylhomocysteinase
compare
MMP
_RS04890
-1.8
-1.4
adenylyltransferase/cytidyltransferase family protein
compare
MMP
_RS04685
-1.8
-6.1
DUF126 domain-containing protein
compare
MMP
_RS05875
-1.7
-7.0
hydroxyethylthiazole kinase
compare
MMP
_RS08635
-1.7
-3.5
UbiA family prenyltransferase
compare
MMP
_RS06625
-1.6
-3.6
DNA primase
compare
MMP
_RS00110
-1.6
-5.6
hypothetical protein
compare
MMP
_RS07525
-1.6
-8.0
4Fe-4S binding protein
compare
MMP
_RS06285
-1.6
-3.5
precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
compare
MMP
_RS00685
-1.6
-5.8
2-phospho-L-lactate guanylyltransferase
compare
MMP
_RS07735
-1.6
-1.5
2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
compare
MMP
_RS01220
-1.6
-7.1
hypothetical protein
compare
MMP
_RS07730
-1.5
-3.3
pyruvate synthase subunit beta
compare
MMP
_RS06340
-1.5
-7.2
phosphoadenosine phosphosulfate reductase family protein
compare
MMP
_RS06270
-1.5
-7.6
TIGR00300 family protein
compare
MMP
_RS04585
-1.5
-7.7
AIR synthase related protein
compare
MMP
_RS08300
-1.5
-2.0
metal-sulfur cluster assembly factor
compare
MMP
_RS06020
-1.4
-5.8
archaeoflavoprotein AfpA
compare
MMP
_RS06315
-1.4
-1.4
cobalt-precorrin-7 (C(5))-methyltransferase
compare
MMP
_RS00695
-1.4
-1.6
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMP
_RS08320
-1.4
-9.4
molybdopterin molybdotransferase MoeA
compare
MMP
_RS05815
-1.4
-2.3
NOL1/NOP2/sun family putative RNA methylase
compare
MMP
_RS00515
-1.3
-1.6
DUF655 domain-containing protein
compare
MMP
_RS05540
-1.3
-3.7
hypothetical protein
compare
MMP
_RS09020
-1.3
-2.8
hypothetical protein
compare
MMP
_RS01795
-1.3
-2.3
methanogenesis marker 6 protein
compare
MMP
_RS07765
-1.3
-7.5
sodium:alanine symporter family protein
compare
MMP
_RS08645
-1.3
-7.5
UPF0179 family protein
compare
MMP
_RS01610
-1.3
-4.5
hypothetical protein
compare
MMP
_RS01225
-1.3
-7.1
DUF5379 domain-containing protein
compare
MMP
_RS02875
-1.3
-7.7
chorismate pyruvate-lyase family protein
compare
MMP
_RS03960
-1.2
-1.3
hypothetical protein
compare
MMP
_RS03400
-1.2
-3.9
archease
compare
MMP
_RS07545
-1.2
-1.7
HTH domain-containing protein
compare
MMP
_RS02235
-1.2
-9.1
CBS domain-containing protein
compare
MMP
_RS03640
-1.1
-3.3
archaeal proteasome endopeptidase complex subunit beta
compare
MMP
_RS06475
-1.1
-5.0
FAD-dependent oxidoreductase
compare
MMP
_RS06730
-1.1
-2.4
phosphopantothenate/pantothenate synthetase
compare
MMP
_RS05245
-1.1
-7.8
archaeosine biosynthesis radical SAM protein RaSEA
compare
MMP
_RS06120
-1.1
-2.7
UPF0147 family protein
compare
MMP
_RS03445
-1.1
-1.6
methanogenesis marker 17 protein
compare
MMP
_RS01250
-1.1
-4.6
tRNA (guanine(26)-N(2))-dimethyltransferase
compare
MMP
_RS02135
-1.1
-3.6
DUF5612 domain-containing protein
compare
MMP
_RS07755
-1.0
-1.9
DUF555 domain-containing protein
compare
MMP
_RS01800
-1.0
-4.0
TIGR00303 family protein
compare
MMP
_RS08790
-1.0
-2.6
translation initiation factor IF-2 subunit alpha
compare
MMP
_RS01325
-1.0
-2.1
dihydroneopterin aldolase family protein
compare
MMP
_RS04615
-1.0
-4.5
PDGLE domain-containing protein
compare
MMP
_RS02245
-1.0
-4.7
hypothetical protein
compare
MMP
_RS06105
-1.0
-5.9
hydrogenase maturation peptidase HycI
compare
MMP
_RS07350
-1.0
-2.8
preprotein translocase subunit Sec61beta
compare
MMP
_RS02165
-1.0
-4.9
tRNA-dihydrouridine synthase
compare
MMP
_RS06895
-1.0
-2.0
selenocysteine-specific translation elongation factor
compare
MMP
_RS02345
-1.0
-3.2
GTP-dependent dephospho-CoA kinase family protein
compare
MMP
_RS00320
-1.0
-2.7
class I SAM-dependent methyltransferase
compare
MMP
_RS08650
-1.0
-2.7
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMP
_RS04605
-1.0
-4.7
cobalt ECF transporter T component CbiQ
compare
MMP
_RS06925
-1.0
-2.3
ribonuclease VapC4
compare
MMP
_RS08200
-1.0
-7.8
archaeosine synthase subunit alpha
compare
MMP
_RS06230
-1.0
-2.3
helix-turn-helix domain-containing protein
compare
MMP
_RS07380
-1.0
-2.6
transcription elongation factor Spt5
compare
MMP
_RS00060
-1.0
-2.1
3-dehydroquinate synthase II
compare
MMP
_RS03435
-1.0
-2.6
ketol-acid reductoisomerase
compare
MMP
_RS02190
-0.9
-2.0
sulfopyruvate decarboxylase subunit alpha
compare
MMP
_RS07750
-0.9
-3.7
DUF357 domain-containing protein
compare
MMP
_RS03035
-0.9
-3.1
4-hydroxy-tetrahydrodipicolinate synthase
compare
MMP
_RS00290
-0.9
-4.2
hypothetical protein
compare
MMP
_RS01385
-0.9
-0.9
imidazole glycerol phosphate synthase subunit HisH
compare
MMP
_RS08725
-0.9
-2.7
Ni/Fe hydrogenase subunit alpha
compare
MMP
_RS01980
-0.9
-7.4
trimeric intracellular cation channel family protein
compare
MMP
_RS06175
-0.9
-5.8
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS04850
-0.9
-7.5
UPF0254 family protein
compare
MMP
_RS07630
-0.9
-1.5
ATP-binding cassette domain-containing protein
compare
MMP
_RS07700
-0.9
-5.5
DUF1188 domain-containing protein
compare
MMP
_RS05265
-0.9
-1.9
2-isopropylmalate synthase
compare
MMP
_RS00730
-0.9
-3.8
5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
compare
MMP
_RS01720
-0.9
-1.2
replication factor C large subunit
compare
MMP
_RS07555
-0.8
-1.0
monovalent cation/H+ antiporter subunit E
compare
MMP
_RS02885
-0.8
-6.9
molybdopterin biosynthesis protein
compare
MMP
_RS07005
-0.8
-0.7
4Fe-4S binding protein
compare
MMP
_RS03155
-0.8
-5.9
precorrin-6A reductase
compare
MMP
_RS06200
-0.8
-6.1
M24 family metallopeptidase
compare
MMP
_RS01890
-0.8
-3.2
nucleotide sugar dehydrogenase
compare
MMP
_RS07200
-0.8
-3.9
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMP
_RS06865
-0.8
-1.8
HypC/HybG/HupF family hydrogenase formation chaperone
compare
MMP
_RS05345
-0.8
-3.9
hypothetical protein
compare
MMP
_RS05445
-0.8
-5.2
CoB--CoM heterodisulfide reductase subunit B
compare
MMP
_RS07435
-0.8
-2.4
GMP synthase subunit A
compare
MMP
_RS03580
-0.8
-2.6
signal recognition particle-docking protein FtsY
compare
MMP
_RS07535
-0.8
-5.7
4Fe-4S binding protein
compare
MMP
_RS06395
-0.8
-3.6
ThiF family adenylyltransferase
compare
MMP
_RS08915
-0.8
-1.9
2 5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase
compare
MMP
_RS05430
-0.8
-4.1
TIGR00288 family NYN domain-containing protein
compare
MMP
_RS08715
-0.8
-2.1
formylmethanofuran dehydrogenase subunit B
compare
MMP
_RS03555
-0.8
-4.8
transcriptional regulator
compare
MMP
_RS01335
-0.8
-3.0
prefoldin subunit beta
compare
MMP
_RS00315
-0.8
-4.3
Nif3-like dinuclear metal center hexameric protein
compare
MMP
_RS00305
-0.8
-1.0
phosphoribosyl-ATP diphosphatase
compare
MMP
_RS04870
-0.8
-3.0
TIGR02253 family HAD-type hydrolase
compare
MMP
_RS06370
-0.7
-3.5
biotin synthase BioB
compare
MMP
_RS01240
-0.7
-1.1
7-cyano-7-deazaguanine synthase QueC
compare
MMP
_RS01365
-0.7
-3.3
archaeal proteasome endopeptidase complex subunit alpha
compare
MMP
_RS02145
-0.7
-3.1
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS05510
-0.7
-4.3
Rrf2 family transcriptional regulator
compare
MMP
_RS06215
-0.7
-3.1
30S ribosomal protein S6e
compare
MMP
_RS06885
-0.7
-2.5
50S ribosome-binding GTPase
compare
MMP
_RS08330
-0.7
-4.3
NADH-quinone oxidoreductase subunit H
compare
MMP
_RS05545
-0.7
-2.6
pyridoxal phosphate-dependent aminotransferase
compare
MMP
_RS07580
-0.7
-1.6
DUF356 domain-containing protein
compare
MMP
_RS07605
-0.7
-2.0
diadenylate cyclase
compare
MMP
_RS03470
-0.7
-5.0
phosphoadenosine phosphosulfate reductase family protein
compare
MMP
_RS05060
-0.7
-5.4
AAA family ATPase
compare
MMP
_RS00120
-0.7
-4.5
LysR family transcriptional regulator
compare
MMP
_RS04875
-0.7
-3.4
energy-converting hydrogenase B subunit P
compare
MMP
_RS01180
-0.7
-0.9
XTP/dITP diphosphatase
compare
MMP
_RS00620
-0.7
-4.9
4Fe-4S binding protein
compare
MMP
_RS01985
-0.7
-3.0
F420-dependent methylenetetrahydromethanopterin dehydrogenase
compare
MMP
_RS04710
-0.7
-1.7
hypothetical protein
compare
MMP
_RS07695
-0.7
-3.9
DUF3236 domain-containing protein
compare
MMP
_RS06975
-0.7
-1.3
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMP
_RS00735
-0.7
-2.2
5 10-methenyltetrahydromethanopterin hydrogenase
compare
MMP
_RS01030
-0.7
-1.4
MTAP family purine nucleoside phosphorylase
compare
MMP
_RS01780
-0.6
-3.8
TrmJ/YjtD family RNA methyltransferase
compare
MMP
_RS05450
-0.6
-3.7
CoB--CoM heterodisulfide reductase subunit C
compare
MMP
_RS02340
-0.6
-1.0
DNA-directed RNA polymerase subunit E''
compare
MMP
_RS05925
-0.6
-2.9
small nuclear ribonucleoprotein
compare
MMP
_RS00050
-0.6
-3.5
AarF/UbiB family protein
compare
MMP
_RS05765
-0.6
-3.4
M42 family metallopeptidase
compare
MMP
_RS00810
-0.6
-3.8
topoisomerase DNA-binding C4 zinc finger domain-containing protein
compare
MMP
_RS05100
-0.6
-5.5
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
compare
MMP
_RS07530
-0.6
-4.3
4Fe-4S binding protein
compare
MMP
_RS07365
-0.6
-4.8
2-phosphoglycerate kinase
compare
MMP
_RS05440
-0.6
-4.5
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS05095
-0.6
-4.2
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMP
_RS08095
-0.6
-3.3
dethiobiotin synthase
compare
MMP
_RS08070
-0.6
-3.6
DUF2096 domain-containing protein
compare
MMP
_RS04500
-0.6
-4.9
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
MMP
_RS02265
-0.6
-3.0
nitroreductase family protein
compare
MMP
_RS04620
-0.6
-4.5
cobalt transporter CbiM
compare
MMP
_RS07685
-0.6
-3.9
TIGR01212 family radical SAM protein
compare
MMP
_RS05850
-0.6
-2.5
Ldh family oxidoreductase
compare
MMP
_RS05070
-0.6
-3.1
4Fe-4S dicluster domain-containing protein
compare
MMP
_RS00720
-0.6
-4.0
metal-dependent hydrolase
compare
MMP
_RS07425
-0.6
-3.2
GTP-binding protein
compare
MMP
_RS03095
-0.6
-3.8
diphthine synthase
compare
MMP
_RS08100
-0.6
-3.9
8-amino-7-oxononanoate synthase
compare
MMP
_RS05065
-0.6
-2.3
CooT family nickel-binding protein
compare
MMP
_RS06860
-0.6
-1.8
4Fe-4S binding protein
compare
MMP
_RS00725
-0.5
-2.6
5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
compare
MMP
_RS08370
-0.5
-0.6
cation:proton antiporter subunit C
compare
MMP
_RS05425
-0.5
-3.0
monovalent cation/H+ antiporter complex subunit F
compare
MMP
_RS06525
-0.5
-1.2
YciI family protein
compare
MMP
_RS07775
-0.5
-3.6
alanine dehydrogenase
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis S2 in stress experiments