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Experiment set5IT024 for
Methanococcus maripaludis S2
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H2 deepwell autotrophic conditions
200 most important genes:
gene
name
fitness
t score
description
MMP
_RS03315
-5.4
-1.7
ferrous iron transport protein A
compare
MMP
_RS03475
-4.5
-0.8
hypothetical protein
compare
MMP
_RS07735
-2.8
-1.2
2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
compare
MMP
_RS05515
-2.4
-10.5
cyclic pyranopterin monophosphate synthase MoaC
compare
MMP
_RS07630
-2.4
-2.1
ATP-binding cassette domain-containing protein
compare
MMP
_RS03450
-2.4
-3.1
glycine synthesis protein GlyXS
(from data)
compare
MMP
_RS03435
-2.3
-2.4
ketol-acid reductoisomerase
compare
MMP
_RS05550
-2.3
-1.0
cation:proton antiporter
compare
MMP
_RS03015
-2.2
-11.5
GTP 3' 8-cyclase MoaA
compare
MMP
_RS06355
-2.2
-3.4
molybdenum cofactor biosynthesis protein MoaE
compare
MMP
_RS05425
-2.2
-5.5
monovalent cation/H+ antiporter complex subunit F
compare
MMP
_RS05555
-2.2
-1.8
DUF4040 domain-containing protein
compare
MMP
_RS07555
-2.1
-0.9
monovalent cation/H+ antiporter subunit E
compare
MMP
_RS02010
-2.1
-9.3
PHP domain-containing protein
compare
MMP
_RS02195
-2.0
-5.0
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
compare
MMP
_RS09020
-2.0
-2.0
hypothetical protein
compare
MMP
_RS06350
-2.0
-8.3
HesA/MoeB/ThiF family protein
compare
MMP
_RS00695
-2.0
-1.1
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMP
_RS04605
-2.0
-5.8
cobalt ECF transporter T component CbiQ
compare
MMP
_RS04620
-2.0
-11.7
cobalt transporter CbiM
compare
MMP
_RS07845
-2.0
-3.1
LL-diaminopimelate aminotransferase
compare
MMP
_RS05500
-2.0
-8.1
2-isopropylmalate synthase
compare
MMP
_RS07635
-1.9
-7.8
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMP
_RS01175
-1.9
-4.8
triphosphoribosyl-dephospho-CoA synthase
compare
MMP
_RS07345
-1.9
-6.0
glycine synthesis protein GlyXL
(from data)
compare
MMP
_RS06270
-1.9
-7.7
TIGR00300 family protein
compare
MMP
_RS01005
-1.8
-1.6
riboflavin synthase
compare
MMP
_RS06370
-1.8
-5.2
biotin synthase BioB
compare
MMP
_RS06485
-1.8
-1.2
zinc ribbon domain-containing protein
compare
MMP
_RS00110
-1.7
-3.6
hypothetical protein
compare
MMP
_RS07575
-1.7
-4.4
RNA ligase partner protein
compare
MMP
_RS03035
-1.7
-3.7
4-hydroxy-tetrahydrodipicolinate synthase
compare
MMP
_RS03445
-1.7
-1.2
methanogenesis marker 17 protein
compare
MMP
_RS08745
-1.7
-6.1
CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMP
_RS03420
-1.7
-4.5
acetolactate synthase small subunit
compare
MMP
_RS05920
-1.7
-0.8
50S ribosomal protein L37e
compare
MMP
_RS04615
-1.7
-4.7
PDGLE domain-containing protein
compare
MMP
_RS01225
-1.7
-4.4
DUF5379 domain-containing protein
compare
MMP
_RS05060
-1.7
-10.9
AAA family ATPase
compare
MMP
_RS01455
-1.7
-6.7
nickel pincer cofactor biosynthesis protein LarC
compare
MMP
_RS06295
-1.6
-7.6
methanogenesis marker 14 protein
compare
MMP
_RS01755
-1.6
-1.5
DUF2097 domain-containing protein
compare
MMP
_RS06730
-1.6
-1.9
phosphopantothenate/pantothenate synthetase
compare
MMP
_RS02885
-1.6
-11.2
molybdopterin biosynthesis protein
compare
MMP
_RS06680
-1.6
-8.7
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
compare
MMP
_RS05080
-1.5
-9.9
acetyl-CoA decarbonylase/synthase complex subunit delta
compare
MMP
_RS08725
-1.5
-2.5
Ni/Fe hydrogenase subunit alpha
compare
MMP
_RS05100
-1.5
-12.0
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
compare
MMP
_RS04500
-1.5
-10.7
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
MMP
_RS07185
-1.5
-10.9
pyridoxal phosphate-dependent aminotransferase
compare
MMP
_RS07730
-1.5
-2.1
pyruvate synthase subunit beta
compare
MMP
_RS08320
-1.5
-6.2
molybdopterin molybdotransferase MoeA
compare
MMP
_RS06340
-1.5
-6.1
phosphoadenosine phosphosulfate reductase family protein
compare
MMP
_RS05095
-1.5
-7.5
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMP
_RS04215
-1.4
-8.6
nickel pincer cofactor biosynthesis protein LarB
compare
MMP
_RS01265
-1.4
-2.3
hypothetical protein
compare
MMP
_RS03390
-1.4
-7.2
malate dehydrogenase
compare
MMP
_RS08360
-1.4
-4.3
hypothetical protein
compare
MMP
_RS04780
-1.4
-3.0
ribonuclease P
compare
MMP
_RS07645
-1.4
-5.9
aldehyde dehydrogenase family protein
compare
MMP
_RS02280
-1.4
-1.0
DUF211 domain-containing protein
compare
MMP
_RS05090
-1.4
-7.8
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
MMP
_RS06400
-1.4
-1.5
4Fe-4S binding protein
compare
MMP
_RS05075
-1.4
-10.6
acetyl-CoA decarbonylase/synthase complex subunit gamma
compare
MMP
_RS08105
-1.4
-6.3
6-carboxyhexanoate--CoA ligase
compare
MMP
_RS08330
-1.4
-6.0
NADH-quinone oxidoreductase subunit H
compare
MMP
_RS02235
-1.4
-7.0
CBS domain-containing protein
compare
MMP
_RS05065
-1.4
-4.8
CooT family nickel-binding protein
compare
MMP
_RS08095
-1.4
-5.9
dethiobiotin synthase
compare
MMP
_RS06105
-1.4
-7.1
hydrogenase maturation peptidase HycI
compare
MMP
_RS01220
-1.4
-6.6
hypothetical protein
compare
MMP
_RS08100
-1.4
-7.4
8-amino-7-oxononanoate synthase
compare
MMP
_RS01960
-1.4
-0.7
hypothetical protein
compare
MMP
_RS01020
-1.3
-1.1
3 4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMP
_RS01800
-1.3
-4.2
TIGR00303 family protein
compare
MMP
_RS03600
-1.3
-1.9
triose-phosphate isomerase
compare
MMP
_RS01610
-1.3
-3.1
hypothetical protein
compare
MMP
_RS05055
-1.3
-8.7
DUF166 domain-containing protein
compare
MMP
_RS06700
-1.3
-7.0
hypothetical protein
compare
MMP
_RS06705
-1.3
-5.1
formate/nitrite transporter family protein
compare
MMP
_RS06345
-1.3
-5.5
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMP
_RS08335
-1.3
-6.7
NADH-quinone oxidoreductase subunit B family protein
compare
MMP
_RS02355
-1.3
-2.3
30S ribosomal protein S27ae
compare
MMP
_RS05070
-1.3
-7.1
4Fe-4S dicluster domain-containing protein
compare
MMP
_RS07955
-1.3
-5.3
FumA C-terminus/TtdB family hydratase beta subunit
compare
MMP
_RS00735
-1.3
-3.5
5 10-methenyltetrahydromethanopterin hydrogenase
compare
MMP
_RS00750
-1.3
-2.1
fumarate hydratase
compare
MMP
_RS05085
-1.3
-6.0
AAA family ATPase
compare
MMP
_RS00130
-1.2
-1.0
nickel-responsive transcriptional regulator NikR
compare
MMP
_RS02135
-1.2
-4.8
DUF5612 domain-containing protein
compare
MMP
_RS04790
-1.2
-8.5
4-hydroxy-tetrahydrodipicolinate reductase
compare
MMP
_RS02900
-1.2
-0.5
imidazoleglycerol-phosphate dehydratase HisB
compare
MMP
_RS08165
-1.2
-1.5
phosphoglycerate dehydrogenase
compare
MMP
_RS07355
-1.2
-0.9
transcription factor S
compare
MMP
_RS06375
-1.2
-4.8
ATP-dependent sacrificial sulfur transferase LarE
compare
MMP
_RS04685
-1.2
-2.9
DUF126 domain-containing protein
compare
MMP
_RS06925
-1.2
-2.3
ribonuclease VapC4
compare
MMP
_RS08995
-1.2
-1.4
hypothetical protein
compare
MMP
_RS07525
-1.2
-6.4
4Fe-4S binding protein
compare
MMP
_RS00685
-1.2
-3.9
2-phospho-L-lactate guanylyltransferase
compare
MMP
_RS08300
-1.2
-1.1
metal-sulfur cluster assembly factor
compare
MMP
_RS04720
-1.2
-2.3
DedA family protein
compare
MMP
_RS06685
-1.2
-6.9
formate dehydrogenase H subunit alpha selenocysteine-containing
compare
MMP
_RS05540
-1.2
-2.8
hypothetical protein
compare
MMP
_RS01700
-1.2
-0.8
dihydroxy-acid dehydratase
compare
MMP
_RS07195
-1.1
-6.9
M20 family metallo-hydrolase
compare
MMP
_RS03145
-1.1
-3.4
fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
compare
MMP
_RS04890
-1.1
-0.7
adenylyltransferase/cytidyltransferase family protein
compare
MMP
_RS08715
-1.1
-1.2
formylmethanofuran dehydrogenase subunit B
compare
MMP
_RS03700
-1.1
-5.8
sodium:proton antiporter
compare
MMP
_RS04875
-1.1
-3.2
energy-converting hydrogenase B subunit P
compare
MMP
_RS01380
-1.1
-2.4
PHP domain-containing protein
compare
MMP
_RS06865
-1.1
-1.6
HypC/HybG/HupF family hydrogenase formation chaperone
compare
MMP
_RS08240
-1.1
-4.1
methanogenesis marker 16 metalloprotein
compare
MMP
_RS05265
-1.1
-1.7
2-isopropylmalate synthase
compare
MMP
_RS04775
-1.1
-2.5
adenosylhomocysteinase
compare
MMP
_RS03250
-1.1
-3.5
MJ1244 family protein
compare
MMP
_RS06475
-1.1
-4.1
FAD-dependent oxidoreductase
compare
MMP
_RS04710
-1.1
-1.3
hypothetical protein
compare
MMP
_RS08645
-1.1
-4.9
UPF0179 family protein
compare
MMP
_RS03095
-1.1
-5.0
diphthine synthase
compare
MMP
_RS03155
-1.1
-4.7
precorrin-6A reductase
compare
MMP
_RS06020
-1.0
-3.7
archaeoflavoprotein AfpA
compare
MMP
_RS08210
-1.0
-1.9
phosphatidylglycerophosphatase A
compare
MMP
_RS03140
-1.0
-5.8
hypothetical protein
compare
MMP
_RS02875
-1.0
-5.3
chorismate pyruvate-lyase family protein
compare
MMP
_RS05875
-1.0
-4.0
hydroxyethylthiazole kinase
compare
MMP
_RS07445
-1.0
-3.7
helix-turn-helix domain-containing protein
compare
MMP
_RS03025
-1.0
-4.0
molybdenum cofactor guanylyltransferase
compare
MMP
_RS06630
-1.0
-0.7
UPF0058 family protein
compare
MMP
_RS07545
-1.0
-0.8
HTH domain-containing protein
compare
MMP
_RS02800
-1.0
-3.0
nucleotidyltransferase domain-containing protein
compare
MMP
_RS08340
-1.0
-3.0
4Fe-4S binding protein
compare
MMP
_RS06885
-1.0
-1.9
50S ribosome-binding GTPase
compare
MMP
_RS04055
-1.0
-1.4
hypothetical protein
compare
MMP
_RS02240
-0.9
-2.1
methanogenesis marker 7 protein
compare
MMP
_RS07390
-0.9
-1.4
cell division protein FtsZ
compare
MMP
_RS07580
-0.9
-2.3
DUF356 domain-containing protein
compare
MMP
_RS07750
-0.9
-3.2
DUF357 domain-containing protein
compare
MMP
_RS07720
-0.9
-6.3
4Fe-4S binding protein
compare
MMP
_RS03400
-0.9
-2.0
archease
compare
MMP
_RS02045
-0.9
-1.4
tRNA-Met
compare
MMP
_RS01240
-0.9
-1.7
7-cyano-7-deazaguanine synthase QueC
compare
MMP
_RS05950
-0.9
-4.4
nickel-dependent hydrogenase large subunit
compare
MMP
_RS01500
-0.9
-1.5
CBS domain-containing protein
compare
MMP
_RS08350
-0.9
-0.8
hypothetical protein
compare
MMP
_RS08365
-0.9
-2.4
energy conserving hydrogenase EhbF
compare
MMP
_RS07600
-0.9
-1.6
Ni-sirohydrochlorin a c-diamide synthase
compare
MMP
_RS02245
-0.9
-2.8
hypothetical protein
compare
MMP
_RS01195
-0.9
-1.0
metalloregulator ArsR/SmtB family transcription factor
compare
MMP
_RS00345
-0.9
-2.2
DUF2666 domain-containing protein
compare
MMP
_RS02805
-0.9
-1.0
HEPN domain-containing protein
compare
MMP
_RS06285
-0.9
-1.5
precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
compare
MMP
_RS06625
-0.9
-1.4
DNA primase
compare
MMP
_RS05445
-0.9
-4.3
CoB--CoM heterodisulfide reductase subunit B
compare
MMP
_RS01775
-0.9
-1.2
TIGR00297 family protein
compare
MMP
_RS00120
-0.9
-2.8
LysR family transcriptional regulator
compare
MMP
_RS02935
-0.8
-3.7
A24 family peptidase
compare
MMP
_RS03640
-0.8
-2.5
archaeal proteasome endopeptidase complex subunit beta
compare
MMP
_RS08415
-0.8
-2.5
radical SAM protein
compare
MMP
_RS03485
-0.8
-1.8
TIGR00267 family protein
compare
MMP
_RS05815
-0.8
-1.2
NOL1/NOP2/sun family putative RNA methylase
compare
MMP
_RS06495
-0.8
-2.6
YkgJ family cysteine cluster protein
compare
MMP
_RS08820
-0.8
-2.2
hypothetical protein
compare
MMP
_RS01260
-0.8
-3.2
HDIG domain-containing protein
compare
MMP
_RS05925
-0.8
-2.0
small nuclear ribonucleoprotein
compare
MMP
_RS07710
-0.8
-4.7
cell division protein FtsZ
compare
MMP
_RS02345
-0.8
-1.8
GTP-dependent dephospho-CoA kinase family protein
compare
MMP
_RS08635
-0.8
-1.3
UbiA family prenyltransferase
compare
MMP
_RS04785
-0.8
-5.2
hypothetical protein
compare
MMP
_RS01905
-0.8
-5.7
glycosyltransferase
compare
MMP
_RS08355
-0.8
-2.8
Na(+)/H(+) antiporter subunit B
compare
MMP
_RS02175
-0.8
-0.6
DUF1611 domain-containing protein
compare
MMP
_RS07350
-0.8
-1.1
preprotein translocase subunit Sec61beta
compare
MMP
_RS06290
-0.8
-3.0
DNA repair and recombination protein RadA
compare
MMP
_RS03440
-0.8
-0.8
MoaD/ThiS family protein
compare
MMP
_RS01795
-0.8
-1.0
methanogenesis marker 6 protein
compare
MMP
_RS01545
-0.8
-0.5
CBS domain-containing protein
compare
MMP
_RS04695
-0.8
-4.1
selenide water dikinase SelD
compare
MMP
_RS07755
-0.7
-0.8
DUF555 domain-containing protein
compare
MMP
_RS04850
-0.7
-5.9
UPF0254 family protein
compare
MMP
_RS06895
-0.7
-0.9
selenocysteine-specific translation elongation factor
compare
MMP
_RS00895
-0.7
-2.2
hypothetical protein
compare
MMP
_RS06670
-0.7
-2.3
glucose-6-phosphate isomerase
compare
MMP
_RS02610
-0.7
-2.7
DUF2162 domain-containing protein
compare
MMP
_RS07425
-0.7
-2.7
GTP-binding protein
compare
MMP
_RS05835
-0.7
-0.6
secondary thiamine-phosphate synthase enzyme YjbQ
compare
MMP
_RS06120
-0.7
-1.3
UPF0147 family protein
compare
MMP
_RS01910
-0.7
-4.3
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMP
_RS06720
-0.7
-2.9
response regulator transcription factor
compare
MMP
_RS00315
-0.7
-2.4
Nif3-like dinuclear metal center hexameric protein
compare
MMP
_RS08345
-0.7
-4.6
4Fe-4S binding protein
compare
MMP
_RS00720
-0.7
-3.9
metal-dependent hydrolase
compare
MMP
_RS06215
-0.7
-0.9
30S ribosomal protein S6e
compare
MMP
_RS01420
-0.7
-1.2
hypothetical protein
compare
MMP
_RS04420
-0.7
-2.7
LysE family translocator
compare
MMP
_RS01915
-0.7
-5.1
DUF354 domain-containing protein
compare
MMP
_RS08445
-0.7
-2.7
DUF2099 family protein
compare
MMP
_RS07860
-0.7
-0.4
hypothetical protein
compare
MMP
_RS05420
-0.6
-2.6
DUF61 family protein
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis S2 in nutrient t1 experiments