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Experiment set5IT024 for
Methanococcus maripaludis S2
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H2 deepwell autotrophic conditions
200 most detrimental genes:
gene
name
fitness
t score
description
MMP
_RS03615
+2.5
18.5
4Fe-4S binding protein
compare
MMP
_RS03620
+2.1
13.7
hypothetical protein
compare
MMP
_RS04550
+1.5
11.7
S-layer protein
compare
MMP
_RS00240
+1.2
8.7
type II secretion system F family protein
compare
MMP
_RS01310
+1.2
7.7
hypothetical protein
compare
MMP
_RS08860
+1.1
4.4
MinD/ParA family protein
compare
MMP
_RS08855
+1.1
5.2
hypothetical protein
compare
MMP
_RS05635
+1.0
6.0
NAD-dependent epimerase/dehydratase family protein
compare
MMP
_RS07330
+1.0
8.2
membrane protein
compare
MMP
_RS01285
+1.0
5.4
hypothetical protein
compare
MMP
_RS01290
+1.0
5.5
class III signal peptide-containing protein
compare
MMP
_RS07125
+0.9
3.5
coenzyme F420-reducing hydrogenase FrhD protein
compare
MMP
_RS01270
+0.9
6.1
prepilin peptidase
compare
MMP
_RS08930
+0.9
2.2
hypothetical protein
compare
MMP
_RS00245
+0.9
7.6
type II secretion system F family protein
compare
MMP
_RS02675
+0.9
2.5
hypothetical protein
compare
MMP
_RS04520
+0.9
2.1
nucleoside deaminase
compare
MMP
_RS01295
+0.9
5.4
hypothetical protein
compare
MMP
_RS02490
+0.9
2.8
hypothetical protein
compare
MMP
_RS01305
+0.9
6.5
hypothetical protein
compare
MMP
_RS00250
+0.8
6.1
Flp pilus assembly complex ATPase component TadA
compare
MMP
_RS06035
+0.8
5.2
glycosyltransferase family 2 protein
compare
MMP
_RS01165
+0.8
2.9
DUF434 domain-containing protein
compare
MMP
_RS06745
+0.7
2.7
DUF2119 domain-containing protein
compare
MMP
_RS08675
+0.7
1.8
class III signal peptide-containing protein
compare
MMP
_RS08775
+0.7
2.7
methanogenesis marker 9 domain-containing protein
compare
MMP
_RS00825
+0.7
1.8
fumarylacetoacetate hydrolase family protein
compare
MMP
_RS08580
+0.7
2.2
flagellin
compare
MMP
_RS03300
+0.7
0.9
TOBE domain-containing protein
compare
MMP
_RS01315
+0.7
6.0
DUF2341 domain-containing protein
compare
MMP
_RS00325
+0.7
1.2
RNA-binding protein
compare
MMP
_RS08665
+0.7
5.2
hypothetical protein
compare
MMP
_RS01280
+0.7
5.5
DUF515 domain-containing protein
compare
MMP
_RS07130
+0.7
3.8
coenzyme F420 hydrogenase subunit gamma
compare
MMP
_RS01370
+0.7
4.4
acetate--CoA ligase family protein
compare
MMP
_RS03520
+0.7
1.9
YwbE family protein
compare
MMP
_RS08785
+0.7
0.8
RNA-protein complex protein Nop10
compare
MMP
_RS00140
+0.7
2.2
DUF192 domain-containing protein
compare
MMP
_RS00675
+0.6
0.9
nitroreductase family protein
compare
MMP
_RS09045
+0.6
4.7
class III signal peptide-containing protein
compare
MMP
_RS03125
+0.6
2.3
cell division ATPase MinD
compare
MMP
_RS05580
+0.6
5.2
glycosyltransferase
compare
MMP
_RS06550
+0.6
2.7
AMP-binding protein
compare
MMP
_RS07890
+0.6
1.6
OB-fold nucleic acid binding domain-containing protein
compare
MMP
_RS09025
+0.6
0.9
hypothetical protein
compare
MMP
_RS02915
+0.6
1.9
amino acid ABC transporter permease
compare
MMP
_RS06500
+0.6
2.5
ATP-binding protein
compare
MMP
_RS06110
+0.6
1.9
ATP-dependent protease LonB
compare
MMP
_RS06070
+0.6
3.7
iron ABC transporter substrate-binding protein
compare
MMP
_RS02475
+0.6
1.2
hypothetical protein
compare
MMP
_RS08215
+0.6
1.0
DUF483 domain-containing protein
compare
MMP
_RS01750
+0.5
3.2
DUF63 family protein
compare
MMP
_RS05250
+0.5
0.6
NFYB/HAP3 family transcription factor subunit
compare
MMP
_RS08130
+0.5
3.1
IGHMBP2 family helicase
compare
MMP
_RS05345
+0.5
3.0
hypothetical protein
compare
MMP
_RS07915
+0.5
1.7
DUF4870 domain-containing protein
compare
MMP
_RS02605
+0.5
0.6
MotA/TolQ/ExbB proton channel family protein
compare
MMP
_RS07895
+0.5
1.8
cytochrome c
compare
MMP
_RS08275
+0.5
2.9
hypothetical protein
compare
MMP
_RS07095
+0.5
1.0
PspC domain-containing protein
compare
MMP
_RS05140
+0.5
1.8
helix-turn-helix transcriptional regulator
compare
MMP
_RS03065
+0.5
1.4
AzlC family ABC transporter permease
compare
MMP
_RS01620
+0.5
1.2
hypothetical protein
compare
MMP
_RS00630
+0.5
2.4
ECF transporter S component
compare
MMP
_RS06530
+0.5
2.1
bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
compare
MMP
_RS03385
+0.5
0.6
cation diffusion facilitator family transporter
compare
MMP
_RS05970
+0.5
1.9
class II SORL domain-containing protein
compare
MMP
_RS02870
+0.4
2.0
hypothetical protein
compare
MMP
_RS07120
+0.4
2.3
coenzyme F420 hydrogenase subunit alpha
compare
MMP
_RS00635
+0.4
1.9
energy-coupling factor transporter transmembrane protein EcfT
compare
MMP
_RS06185
+0.4
1.5
thermonuclease family protein
compare
MMP
_RS08315
+0.4
0.8
S-methyl-5-thioribose-1-phosphate isomerase
compare
MMP
_RS06520
+0.4
2.1
DUF1786 domain-containing protein
compare
MMP
_RS04430
+0.4
1.9
DUF1847 domain-containing protein
compare
MMP
_RS00040
+0.4
2.3
TIGR03576 family pyridoxal phosphate-dependent enzyme
compare
MMP
_RS07815
+0.4
0.7
DUF2120 domain-containing protein
compare
MMP
_RS08090
+0.4
2.1
hypothetical protein
compare
MMP
_RS00990
+0.4
1.8
hypothetical protein
compare
MMP
_RS00395
+0.4
0.8
MGMT family protein
compare
MMP
_RS08670
+0.4
1.5
metallophosphoesterase
compare
MMP
_RS00185
+0.4
3.0
potassium channel protein
compare
MMP
_RS05825
+0.4
1.0
peptidyl-prolyl cis-trans isomerase
compare
MMP
_RS00565
+0.4
1.1
CBS domain-containing protein
compare
MMP
_RS04020
+0.4
1.6
hypothetical protein
compare
MMP
_RS07770
+0.4
2.1
alanine racemase
compare
MMP
_RS06535
+0.4
1.2
2-oxoacid:acceptor oxidoreductase family protein
compare
MMP
_RS03235
+0.4
1.7
tRNA pseudouridine(13) synthase TruD
compare
MMP
_RS03090
+0.4
1.8
cation:proton antiporter
compare
MMP
_RS02595
+0.4
0.7
putative zinc-binding protein
compare
MMP
_RS08620
+0.4
1.7
flagellar accessory protein FlaH
compare
MMP
_RS08410
+0.4
1.4
DUF169 domain-containing protein
compare
MMP
_RS07590
+0.4
2.1
hypothetical protein
compare
MMP
_RS07115
+0.4
2.2
MBL fold metallo-hydrolase
compare
MMP
_RS01660
+0.4
1.3
hypothetical protein
compare
MMP
_RS06910
+0.4
1.8
RlmF-related methyltransferase
compare
MMP
_RS06920
+0.4
2.2
AAA family ATPase
compare
MMP
_RS00450
+0.4
0.7
4Fe-4S binding protein
compare
MMP
_RS07180
+0.4
1.9
DEAD/DEAH box helicase
compare
MMP
_RS05020
+0.4
0.9
hypothetical protein
compare
MMP
_RS05715
+0.4
1.5
hypothetical protein
compare
MMP
_RS01435
+0.4
1.0
DMT family transporter
compare
MMP
_RS07570
+0.4
2.4
nucleotidyltransferase family protein
compare
MMP
_RS07925
+0.4
1.1
haloacid dehalogenase
compare
MMP
_RS01475
+0.4
1.6
phosphosulfolactate synthase
compare
MMP
_RS08470
+0.4
2.0
ATP-binding cassette domain-containing protein
compare
MMP
_RS05720
+0.3
1.7
signal recognition particle subunit SRP19/SEC65 family protein
compare
MMP
_RS08260
+0.3
1.5
DUF99 family protein
compare
MMP
_RS01655
+0.3
0.8
DsrE family protein
compare
MMP
_RS06155
+0.3
1.0
DUF4186 domain-containing protein
compare
MMP
_RS04845
+0.3
1.8
CheF family chemotaxis protein
compare
MMP
_RS00280
+0.3
2.3
DUF2118 domain-containing protein
compare
MMP
_RS05820
+0.3
1.6
RNA-binding transcriptional accessory protein
compare
MMP
_RS03870
+0.3
1.2
purine NTPase
compare
MMP
_RS05695
+0.3
1.7
phospholipase D-like domain-containing protein
compare
MMP
_RS02100
+0.3
1.2
metallophosphoesterase
compare
MMP
_RS01460
+0.3
1.2
hypothetical protein
compare
MMP
_RS07885
+0.3
0.7
tripartite tricarboxylate transporter permease
compare
MMP
_RS01130
+0.3
1.8
flavoprotein
compare
MMP
_RS05785
+0.3
2.3
ATP-binding protein
compare
MMP
_RS02545
+0.3
1.1
hypothetical protein
compare
MMP
_RS00235
+0.3
1.9
HDIG domain-containing protein
compare
MMP
_RS01210
+0.3
1.5
sodium:solute symporter
compare
MMP
_RS05355
+0.3
0.3
hypothetical protein
compare
MMP
_RS08250
+0.3
2.0
pyruvate kinase
compare
MMP
_RS06325
+0.3
0.5
hypothetical protein
compare
MMP
_RS01515
+0.3
1.7
PINc/VapC family ATPase
compare
MMP
_RS06675
+0.3
1.6
ADP-specific phosphofructokinase
compare
MMP
_RS00930
+0.3
1.1
ABC transporter permease
compare
MMP
_RS03900
+0.3
1.6
minichromosome maintenance protein MCM
compare
MMP
_RS00955
+0.3
1.8
coenzyme gamma-F420-2:alpha-L-glutamate ligase
compare
MMP
_RS05675
+0.3
0.7
phosphate ABC transporter ATP-binding protein PstB
compare
MMP
_RS00660
+0.3
1.6
alkaline phosphatase family protein
compare
MMP
_RS08175
+0.3
1.4
7-cyano-7-deazaguanine synthase
compare
MMP
_RS05980
+0.3
1.2
ferritin
compare
MMP
_RS07650
+0.3
1.5
TldD/PmbA family protein
compare
MMP
_RS04105
+0.3
1.2
MarR family transcriptional regulator
compare
MMP
_RS04835
+0.3
1.1
chemotaxis protein CheC
compare
MMP
_RS04090
+0.3
0.7
hypothetical protein
compare
MMP
_RS04475
+0.3
1.0
nitrogen fixation
compare
MMP
_RS00145
+0.3
1.4
ATP-dependent Clp protease proteolytic subunit
compare
MMP
_RS08640
+0.3
1.5
TIM barrel protein
compare
MMP
_RS08200
+0.3
1.9
archaeosine synthase subunit alpha
compare
MMP
_RS06140
+0.3
0.6
radical SAM protein
compare
MMP
_RS06150
+0.3
1.6
hypothetical protein
compare
MMP
_RS08475
+0.3
1.2
ABC transporter permease
compare
MMP
_RS02965
+0.3
1.2
carboxymuconolactone decarboxylase family protein
compare
MMP
_RS00150
+0.3
1.3
AAA family ATPase
compare
MMP
_RS01125
+0.3
1.3
thioredoxin family protein
compare
MMP
_RS08205
+0.3
1.3
stage II sporulation protein M
compare
MMP
_RS01300
+0.3
1.8
hypothetical protein
compare
MMP
_RS02540
+0.3
1.1
DUF2283 domain-containing protein
compare
MMP
_RS04205
+0.3
0.9
carboxymuconolactone decarboxylase family protein
compare
MMP
_RS01095
+0.3
1.0
iron ABC transporter permease
compare
MMP
_RS06365
+0.3
0.5
hypothetical protein
compare
MMP
_RS08625
+0.3
1.5
type II/IV secretion system ATPase subunit
compare
MMP
_RS01185
+0.3
1.0
hypothetical protein
compare
MMP
_RS05790
+0.3
1.1
HDIG domain-containing protein
compare
MMP
_RS05795
+0.3
0.6
redox-regulated ATPase YchF
compare
MMP
_RS02290
+0.3
1.2
MBL fold metallo-hydrolase
compare
MMP
_RS06080
+0.3
1.5
radical SAM protein
compare
MMP
_RS02650
+0.3
1.1
flavodoxin family protein
compare
MMP
_RS07560
+0.2
0.5
prefoldin subunit alpha
compare
MMP
_RS00940
+0.2
1.2
daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein
compare
MMP
_RS06610
+0.2
0.9
DUF2334 domain-containing protein
compare
MMP
_RS07850
+0.2
0.4
prephenate dehydratase
compare
MMP
_RS00960
+0.2
0.8
iron export ABC transporter permease subunit FetB
compare
MMP
_RS06225
+0.2
1.0
DNA double-strand break repair nuclease NurA
compare
MMP
_RS06560
+0.2
1.5
hypothetical protein
compare
MMP
_RS06540
+0.2
0.6
3-methyl-2-oxobutanoate dehydrogenase subunit VorB
compare
MMP
_RS02700
+0.2
1.2
formylmethanofuran dehydrogenase subunit C
compare
MMP
_RS02765
+0.2
0.8
ABC transporter ATP-binding protein
compare
MMP
_RS01075
+0.2
0.2
hypothetical protein
compare
MMP
_RS02340
+0.2
0.3
DNA-directed RNA polymerase subunit E''
compare
MMP
_RS06175
+0.2
0.8
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS01055
+0.2
1.1
hypothetical protein
compare
MMP
_RS03340
+0.2
0.2
ABC transporter ATP-binding protein
compare
MMP
_RS05940
+0.2
0.9
corrinoid protein
compare
MMP
_RS08980
+0.2
0.8
hypothetical protein
compare
MMP
_RS02770
+0.2
0.5
hypothetical protein
compare
MMP
_RS02395
+0.2
1.3
hypothetical protein
compare
MMP
_RS00795
+0.2
1.0
formate dehydrogenase H subunit alpha selenocysteine-containing
compare
MMP
_RS05180
+0.2
1.2
Nre family DNA repair protein
compare
MMP
_RS03895
+0.2
0.6
hypothetical protein
compare
MMP
_RS06085
+0.2
1.7
iron ABC transporter substrate-binding protein
compare
MMP
_RS09065
+0.2
1.6
hypothetical protein
compare
MMP
_RS08705
+0.2
1.2
sulfopyruvate decarboxylase subunit beta
compare
MMP
_RS01060
+0.2
1.3
calcium/sodium antiporter
compare
MMP
_RS04985
+0.2
0.5
DUF2180 family protein
compare
MMP
_RS02710
+0.2
1.1
formylmethanofuran dehydrogenase subunit B
compare
MMP
_RS02360
+0.2
0.7
hypothetical protein
compare
MMP
_RS08385
+0.2
0.8
ABC transporter substrate-binding protein
compare
MMP
_RS01275
+0.2
1.0
class III signal peptide-containing protein
compare
MMP
_RS05910
+0.2
0.6
cell division ATPase MinD
compare
MMP
_RS04700
+0.2
1.0
hypothetical protein
compare
MMP
_RS07550
+0.2
1.2
L-serine ammonia-lyase iron-sulfur-dependent subunit alpha
compare
MMP
_RS05275
+0.2
0.9
AI-2E family transporter
compare
MMP
_RS00700
+0.2
0.8
OB-fold nucleic acid binding domain-containing protein
compare
MMP
_RS02470
+0.2
0.2
helix-turn-helix transcriptional regulator
compare
MMP
_RS01495
+0.2
1.0
TraB/GumN family protein
compare
MMP
_RS00880
+0.2
0.6
ribosome assembly RNA-binding protein YhbY
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis S2 in nutrient t1 experiments