Experiment set5IT023 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS06315		-3.1	-1.3	cobalt-precorrin-7 (C(5))-methyltransferase
MMP_RS07845		-2.5	-3.6	LL-diaminopimelate aminotransferase
MMP_RS06400		-2.5	-2.3	4Fe-4S binding protein
MMP_RS04615		-2.4	-5.5	PDGLE domain-containing protein
MMP_RS01700		-2.2	-1.1	dihydroxy-acid dehydratase
MMP_RS07630		-2.2	-2.0	ATP-binding cassette domain-containing protein
MMP_RS06285		-2.1	-3.0	precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
MMP_RS07755		-2.1	-1.5	DUF555 domain-containing protein
MMP_RS01755		-2.1	-1.7	DUF2097 domain-containing protein
MMP_RS07730		-2.0	-2.7	pyruvate synthase subunit beta
MMP_RS03015		-2.0	-11.7	GTP 3' 8-cyclase MoaA
MMP_RS04605		-2.0	-5.1	cobalt ECF transporter T component CbiQ
MMP_RS02195		-2.0	-4.5	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
MMP_RS03450		-1.9	-3.0	glycine synthesis protein GlyXS (from data)
MMP_RS05515		-1.9	-8.9	cyclic pyranopterin monophosphate synthase MoaC
MMP_RS04620		-1.9	-11.3	cobalt transporter CbiM
MMP_RS07735		-1.9	-1.2	2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
MMP_RS02010		-1.8	-9.4	PHP domain-containing protein
MMP_RS05500		-1.8	-7.6	2-isopropylmalate synthase
MMP_RS07345		-1.8	-6.8	glycine synthesis protein GlyXL (from data)
MMP_RS01005		-1.8	-1.6	riboflavin synthase
MMP_RS06355		-1.7	-3.0	molybdenum cofactor biosynthesis protein MoaE
MMP_RS03435		-1.7	-2.2	ketol-acid reductoisomerase
MMP_RS05550		-1.7	-0.9	cation:proton antiporter
MMP_RS01020		-1.7	-1.3	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS05060		-1.7	-9.6	AAA family ATPase
MMP_RS07600		-1.7	-3.3	Ni-sirohydrochlorin a c-diamide synthase
MMP_RS03640		-1.6	-3.9	archaeal proteasome endopeptidase complex subunit beta
MMP_RS01175		-1.6	-3.7	triphosphoribosyl-dephospho-CoA synthase
MMP_RS06270		-1.6	-5.7	TIGR00300 family protein
MMP_RS07635		-1.6	-6.6	MogA/MoaB family molybdenum cofactor biosynthesis protein
MMP_RS03035		-1.6	-3.4	4-hydroxy-tetrahydrodipicolinate synthase
MMP_RS06370		-1.6	-5.0	biotin synthase BioB
MMP_RS06350		-1.6	-4.6	HesA/MoeB/ThiF family protein
MMP_RS08745		-1.6	-5.0	CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
MMP_RS06860		-1.6	-1.9	4Fe-4S binding protein
MMP_RS01225		-1.5	-5.9	DUF5379 domain-containing protein
MMP_RS03315		-1.5	-1.0	ferrous iron transport protein A
MMP_RS04500		-1.5	-10.7	adenosylmethionine--8-amino-7-oxononanoate transaminase
MMP_RS07005		-1.5	-0.6	4Fe-4S binding protein
MMP_RS05090		-1.5	-9.6	CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
MMP_RS08210		-1.5	-2.7	phosphatidylglycerophosphatase A
MMP_RS02885		-1.5	-10.3	molybdopterin biosynthesis protein
MMP_RS01265		-1.4	-2.3	hypothetical protein
MMP_RS08320		-1.4	-5.2	molybdopterin molybdotransferase MoeA
MMP_RS05095		-1.4	-7.8	CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
MMP_RS01830		-1.4	-1.6	tRNA-Val
MMP_RS02240		-1.4	-3.7	methanogenesis marker 7 protein
MMP_RS01385		-1.3	-0.7	imidazole glycerol phosphate synthase subunit HisH
MMP_RS04780		-1.3	-3.3	ribonuclease P
MMP_RS08105		-1.3	-6.4	6-carboxyhexanoate--CoA ligase
MMP_RS09020		-1.3	-1.4	hypothetical protein
MMP_RS05070		-1.3	-6.6	4Fe-4S dicluster domain-containing protein
MMP_RS05100		-1.3	-10.6	CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
MMP_RS06375		-1.3	-4.0	ATP-dependent sacrificial sulfur transferase LarE
MMP_RS01220		-1.3	-6.2	hypothetical protein
MMP_RS01455		-1.3	-6.3	nickel pincer cofactor biosynthesis protein LarC
MMP_RS06700		-1.3	-8.6	hypothetical protein
MMP_RS05555		-1.3	-1.5	DUF4040 domain-containing protein
MMP_RS07645		-1.3	-4.6	aldehyde dehydrogenase family protein
MMP_RS02135		-1.3	-4.0	DUF5612 domain-containing protein
MMP_RS08330		-1.3	-3.7	NADH-quinone oxidoreductase subunit H
MMP_RS05085		-1.3	-6.3	AAA family ATPase
MMP_RS00750		-1.3	-2.6	fumarate hydratase
MMP_RS05265		-1.3	-2.4	2-isopropylmalate synthase
MMP_RS05055		-1.3	-9.9	DUF166 domain-containing protein
MMP_RS05065		-1.3	-4.0	CooT family nickel-binding protein
MMP_RS06885		-1.3	-2.3	50S ribosome-binding GTPase
MMP_RS08790		-1.3	-1.5	translation initiation factor IF-2 subunit alpha
MMP_RS06105		-1.3	-6.0	hydrogenase maturation peptidase HycI
MMP_RS07575		-1.2	-3.4	RNA ligase partner protein
MMP_RS06340		-1.2	-6.2	phosphoadenosine phosphosulfate reductase family protein
MMP_RS05075		-1.2	-9.7	acetyl-CoA decarbonylase/synthase complex subunit gamma
MMP_RS03400		-1.2	-3.0	archease
MMP_RS07750		-1.2	-3.8	DUF357 domain-containing protein
MMP_RS06680		-1.2	-7.3	Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
MMP_RS03155		-1.2	-5.4	precorrin-6A reductase
MMP_RS05080		-1.2	-8.7	acetyl-CoA decarbonylase/synthase complex subunit delta
MMP_RS02235		-1.2	-6.0	CBS domain-containing protein
MMP_RS05930		-1.2	-1.9	3-isopropylmalate dehydratase large subunit
MMP_RS04790		-1.2	-7.5	4-hydroxy-tetrahydrodipicolinate reductase
MMP_RS07185		-1.2	-8.0	pyridoxal phosphate-dependent aminotransferase
MMP_RS08340		-1.2	-2.9	4Fe-4S binding protein
MMP_RS04710		-1.1	-1.1	hypothetical protein
MMP_RS08095		-1.1	-4.0	dethiobiotin synthase
MMP_RS04685		-1.1	-2.5	DUF126 domain-containing protein
MMP_RS03580		-1.1	-3.3	signal recognition particle-docking protein FtsY
MMP_RS07195		-1.1	-7.5	M20 family metallo-hydrolase
MMP_RS08100		-1.1	-5.1	8-amino-7-oxononanoate synthase
MMP_RS04215		-1.1	-4.9	nickel pincer cofactor biosynthesis protein LarB
MMP_RS00685		-1.1	-2.9	2-phospho-L-lactate guanylyltransferase
MMP_RS03390		-1.1	-5.8	malate dehydrogenase
MMP_RS01960		-1.1	-0.7	hypothetical protein
MMP_RS06345		-1.1	-5.3	formate dehydrogenase accessory sulfurtransferase FdhD
MMP_RS07955		-1.1	-5.1	FumA C-terminus/TtdB family hydratase beta subunit
MMP_RS05425		-1.1	-3.1	monovalent cation/H+ antiporter complex subunit F
MMP_RS07445		-1.1	-5.1	helix-turn-helix domain-containing protein
MMP_RS06925		-1.1	-2.0	ribonuclease VapC4
MMP_RS04775		-1.1	-3.0	adenosylhomocysteinase
MMP_RS02355		-1.0	-2.2	30S ribosomal protein S27ae
MMP_RS07525		-1.0	-5.4	4Fe-4S binding protein
MMP_RS01610		-1.0	-1.9	hypothetical protein
MMP_RS06685		-1.0	-5.9	formate dehydrogenase H subunit alpha selenocysteine-containing
MMP_RS00900		-1.0	-1.8	50S ribosomal protein L39e
MMP_RS03140		-1.0	-6.1	hypothetical protein
MMP_RS03420		-1.0	-2.8	acetolactate synthase small subunit
MMP_RS05540		-1.0	-2.8	hypothetical protein
MMP_RS08240		-1.0	-5.5	methanogenesis marker 16 metalloprotein
MMP_RS07555		-1.0	-0.6	monovalent cation/H+ antiporter subunit E
MMP_RS06865		-1.0	-2.0	HypC/HybG/HupF family hydrogenase formation chaperone
MMP_RS01325		-1.0	-1.6	dihydroneopterin aldolase family protein
MMP_RS08335		-1.0	-4.0	NADH-quinone oxidoreductase subunit B family protein
MMP_RS08725		-1.0	-1.4	Ni/Fe hydrogenase subunit alpha
MMP_RS05925		-0.9	-2.4	small nuclear ribonucleoprotein
MMP_RS08760		-0.9	-1.9	hypothetical protein
MMP_RS02800		-0.9	-3.8	nucleotidyltransferase domain-containing protein
MMP_RS02875		-0.9	-5.6	chorismate pyruvate-lyase family protein
MMP_RS06705		-0.9	-2.7	formate/nitrite transporter family protein
MMP_RS04305		-0.9	-1.9	hypothetical protein
MMP_RS05950		-0.9	-4.5	nickel-dependent hydrogenase large subunit
MMP_RS03700		-0.9	-4.4	sodium:proton antiporter
MMP_RS08300		-0.9	-0.8	metal-sulfur cluster assembly factor
MMP_RS07390		-0.9	-1.7	cell division protein FtsZ
MMP_RS06840		-0.9	-0.8	DNA-directed RNA polymerase subunit N
MMP_RS07380		-0.9	-1.4	transcription elongation factor Spt5
MMP_RS03445		-0.9	-0.8	methanogenesis marker 17 protein
MMP_RS00735		-0.9	-2.9	5 10-methenyltetrahydromethanopterin hydrogenase
MMP_RS06295		-0.9	-3.9	methanogenesis marker 14 protein
MMP_RS08820		-0.9	-2.7	hypothetical protein
MMP_RS00300		-0.9	-0.5	6 7-dimethyl-8-ribityllumazine synthase
MMP_RS07720		-0.9	-6.4	4Fe-4S binding protein
MMP_RS04720		-0.8	-2.1	DedA family protein
MMP_RS08360		-0.8	-2.9	hypothetical protein
MMP_RS03025		-0.8	-2.6	molybdenum cofactor guanylyltransferase
MMP_RS03250		-0.8	-2.3	MJ1244 family protein
MMP_RS00130		-0.8	-0.7	nickel-responsive transcriptional regulator NikR
MMP_RS01500		-0.8	-1.2	CBS domain-containing protein
MMP_RS03095		-0.8	-3.6	diphthine synthase
MMP_RS08350		-0.8	-0.7	hypothetical protein
MMP_RS08650		-0.8	-2.0	glutamine--fructose-6-phosphate transaminase (isomerizing)
MMP_RS02280		-0.8	-0.7	DUF211 domain-containing protein
MMP_RS07545		-0.8	-0.9	HTH domain-containing protein
MMP_RS01195		-0.8	-1.0	metalloregulator ArsR/SmtB family transcription factor
MMP_RS08345		-0.8	-5.3	4Fe-4S binding protein
MMP_RS01725		-0.8	-2.0	class I SAM-dependent methyltransferase family protein
MMP_RS03145		-0.8	-2.2	fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
MMP_RS04875		-0.7	-1.9	energy-converting hydrogenase B subunit P
MMP_RS01800		-0.7	-2.4	TIGR00303 family protein
MMP_RS07625		-0.7	-2.4	cobalt ECF transporter T component CbiQ
MMP_RS06770		-0.7	-3.7	DHH family phosphoesterase
MMP_RS06895		-0.7	-0.9	selenocysteine-specific translation elongation factor
MMP_RS02175		-0.7	-0.6	DUF1611 domain-containing protein
MMP_RS05955		-0.7	-1.4	CoB--CoM heterodisulfide reductase subunit C
MMP_RS08165		-0.7	-1.9	phosphoglycerate dehydrogenase
MMP_RS06730		-0.7	-1.2	phosphopantothenate/pantothenate synthetase
MMP_RS01910		-0.7	-5.0	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
MMP_RS05420		-0.7	-1.9	DUF61 family protein
MMP_RS00520		-0.7	-0.9	RNA polymerase Rpb4 family protein
MMP_RS07580		-0.7	-1.5	DUF356 domain-containing protein
MMP_RS08645		-0.7	-2.9	UPF0179 family protein
MMP_RS07535		-0.7	-4.1	4Fe-4S binding protein
MMP_RS00295		-0.7	-1.4	gamma carbonic anhydrase family protein
MMP_RS05815		-0.7	-1.2	NOL1/NOP2/sun family putative RNA methylase
MMP_RS03475		-0.7	-0.3	hypothetical protein
MMP_RS03395		-0.7	-2.5	hypothetical protein
MMP_RS07075		-0.7	-2.4	phosphomannomutase/phosphoglucomutase
MMP_RS01795		-0.7	-0.8	methanogenesis marker 6 protein
MMP_RS07710		-0.7	-4.5	cell division protein FtsZ
MMP_RS06120		-0.7	-1.0	UPF0147 family protein
MMP_RS04055		-0.7	-1.0	hypothetical protein
MMP_RS05875		-0.7	-2.5	hydroxyethylthiazole kinase
MMP_RS03080		-0.7	-1.5	universal stress protein
MMP_RS06310		-0.6	-2.1	NAD(P)/FAD-dependent oxidoreductase
MMP_RS00985		-0.6	-2.2	CDC48 family AAA ATPase
MMP_RS06930		-0.6	-4.5	MBL fold metallo-hydrolase
MMP_RS03960		-0.6	-0.4	hypothetical protein
MMP_RS02935		-0.6	-1.8	A24 family peptidase
MMP_RS08915		-0.6	-1.5	2 5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase
MMP_RS02130		-0.6	-2.9	zinc metalloprotease HtpX
MMP_RS03555		-0.6	-3.0	transcriptional regulator
MMP_RS01665		-0.6	-2.9	DUF2111 domain-containing protein
MMP_RS07420		-0.6	-2.0	metalloregulator ArsR/SmtB family transcription factor
MMP_RS00720		-0.6	-3.1	metal-dependent hydrolase
MMP_RS07705		-0.6	-3.2	transcriptional regulator
MMP_RS02145		-0.6	-2.9	winged helix-turn-helix transcriptional regulator
MMP_RS01240		-0.6	-1.2	7-cyano-7-deazaguanine synthase QueC
MMP_RS00695		-0.6	-0.5	biotin--[acetyl-CoA-carboxylase] ligase
MMP_RS06720		-0.6	-2.7	response regulator transcription factor
MMP_RS05315		-0.6	-1.3	hypothetical protein
MMP_RS01905		-0.6	-4.7	glycosyltransferase
MMP_RS02410		-0.6	-1.7	ABC transporter substrate-binding protein
MMP_RS01260		-0.6	-2.4	HDIG domain-containing protein
MMP_RS00315		-0.6	-2.5	Nif3-like dinuclear metal center hexameric protein
MMP_RS01380		-0.6	-2.2	PHP domain-containing protein
MMP_RS00965		-0.6	-2.1	hypothetical protein
MMP_RS06475		-0.6	-2.1	FAD-dependent oxidoreductase
MMP_RS02045		-0.6	-1.0	tRNA-Met
MMP_RS08365		-0.6	-1.7	energy conserving hydrogenase EhbF
MMP_RS00305		-0.6	-0.9	phosphoribosyl-ATP diphosphatase
MMP_RS04785		-0.6	-4.3	hypothetical protein

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments