Experiment set5IT022 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS03315		-3.3	-1.9	ferrous iron transport protein A
MMP_RS01385		-2.9	-0.9	imidazole glycerol phosphate synthase subunit HisH
MMP_RS00695		-2.9	-1.2	biotin--[acetyl-CoA-carboxylase] ligase
MMP_RS05265		-2.6	-3.0	2-isopropylmalate synthase
MMP_RS07630		-2.6	-2.2	ATP-binding cassette domain-containing protein
MMP_RS07845		-2.5	-3.0	LL-diaminopimelate aminotransferase
MMP_RS07005		-2.5	-0.7	4Fe-4S binding protein
MMP_RS04615		-2.3	-4.1	PDGLE domain-containing protein
MMP_RS05515		-2.2	-10.2	cyclic pyranopterin monophosphate synthase MoaC
MMP_RS02135		-2.1	-5.2	DUF5612 domain-containing protein
MMP_RS07545		-2.1	-1.2	HTH domain-containing protein
MMP_RS08300		-2.0	-1.5	metal-sulfur cluster assembly factor
MMP_RS03450		-2.0	-2.5	glycine synthesis protein GlyXS (from data)
MMP_RS07575		-1.9	-3.8	RNA ligase partner protein
MMP_RS03015		-1.9	-8.9	GTP 3' 8-cyclase MoaA
MMP_RS01265		-1.9	-3.5	hypothetical protein
MMP_RS01830		-1.9	-1.9	tRNA-Val
MMP_RS04605		-1.8	-5.0	cobalt ECF transporter T component CbiQ
MMP_RS05500		-1.7	-9.4	2-isopropylmalate synthase
MMP_RS08360		-1.7	-5.6	hypothetical protein
MMP_RS09020		-1.7	-1.8	hypothetical protein
MMP_RS07730		-1.7	-2.6	pyruvate synthase subunit beta
MMP_RS01225		-1.7	-4.4	DUF5379 domain-containing protein
MMP_RS01020		-1.7	-1.2	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS04620		-1.7	-10.6	cobalt transporter CbiM
MMP_RS02900		-1.6	-0.6	imidazoleglycerol-phosphate dehydratase HisB
MMP_RS03960		-1.6	-0.8	hypothetical protein
MMP_RS02010		-1.6	-9.3	PHP domain-containing protein
MMP_RS03035		-1.6	-3.3	4-hydroxy-tetrahydrodipicolinate synthase
MMP_RS06285		-1.6	-2.6	precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
MMP_RS00515		-1.6	-1.0	DUF655 domain-containing protein
MMP_RS06355		-1.6	-2.6	molybdenum cofactor biosynthesis protein MoaE
MMP_RS01175		-1.6	-4.6	triphosphoribosyl-dephospho-CoA synthase
MMP_RS04500		-1.6	-11.1	adenosylmethionine--8-amino-7-oxononanoate transaminase
MMP_RS01700		-1.5	-1.0	dihydroxy-acid dehydratase
MMP_RS06400		-1.5	-1.9	4Fe-4S binding protein
MMP_RS06350		-1.5	-5.5	HesA/MoeB/ThiF family protein
MMP_RS08330		-1.5	-5.7	NADH-quinone oxidoreductase subunit H
MMP_RS08165		-1.5	-2.8	phosphoglycerate dehydrogenase
MMP_RS02195		-1.5	-4.1	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
MMP_RS02885		-1.5	-10.8	molybdopterin biosynthesis protein
MMP_RS01455		-1.5	-6.4	nickel pincer cofactor biosynthesis protein LarC
MMP_RS05555		-1.5	-1.6	DUF4040 domain-containing protein
MMP_RS08320		-1.5	-5.3	molybdopterin molybdotransferase MoeA
MMP_RS06295		-1.5	-6.1	methanogenesis marker 14 protein
MMP_RS07600		-1.4	-2.6	Ni-sirohydrochlorin a c-diamide synthase
MMP_RS05060		-1.4	-10.0	AAA family ATPase
MMP_RS00750		-1.4	-2.6	fumarate hydratase
MMP_RS07635		-1.4	-5.3	MogA/MoaB family molybdenum cofactor biosynthesis protein
MMP_RS01220		-1.4	-6.5	hypothetical protein
MMP_RS07955		-1.4	-5.0	FumA C-terminus/TtdB family hydratase beta subunit
MMP_RS04215		-1.4	-6.2	nickel pincer cofactor biosynthesis protein LarB
MMP_RS06370		-1.4	-4.7	biotin synthase BioB
MMP_RS07755		-1.4	-1.1	DUF555 domain-containing protein
MMP_RS05090		-1.4	-8.0	CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
MMP_RS08095		-1.4	-6.4	dethiobiotin synthase
MMP_RS08340		-1.4	-4.1	4Fe-4S binding protein
MMP_RS06375		-1.4	-5.4	ATP-dependent sacrificial sulfur transferase LarE
MMP_RS03420		-1.4	-2.9	acetolactate synthase small subunit
MMP_RS03390		-1.4	-5.4	malate dehydrogenase
MMP_RS05100		-1.4	-10.5	CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
MMP_RS05540		-1.4	-3.7	hypothetical protein
MMP_RS07645		-1.4	-5.4	aldehyde dehydrogenase family protein
MMP_RS08100		-1.4	-5.8	8-amino-7-oxononanoate synthase
MMP_RS01755		-1.4	-1.0	DUF2097 domain-containing protein
MMP_RS05065		-1.3	-5.1	CooT family nickel-binding protein
MMP_RS05425		-1.3	-5.0	monovalent cation/H+ antiporter complex subunit F
MMP_RS06700		-1.3	-8.5	hypothetical protein
MMP_RS03155		-1.3	-6.0	precorrin-6A reductase
MMP_RS06340		-1.3	-6.3	phosphoadenosine phosphosulfate reductase family protein
MMP_RS02280		-1.3	-0.9	DUF211 domain-containing protein
MMP_RS08745		-1.3	-5.5	CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
MMP_RS05080		-1.3	-9.0	acetyl-CoA decarbonylase/synthase complex subunit delta
MMP_RS06120		-1.3	-1.7	UPF0147 family protein
MMP_RS04790		-1.3	-7.6	4-hydroxy-tetrahydrodipicolinate reductase
MMP_RS02235		-1.3	-7.0	CBS domain-containing protein
MMP_RS07345		-1.3	-4.5	glycine synthesis protein GlyXL (from data)
MMP_RS05055		-1.3	-8.8	DUF166 domain-containing protein
MMP_RS05085		-1.3	-5.1	AAA family ATPase
MMP_RS05550		-1.3	-0.7	cation:proton antiporter
MMP_RS05095		-1.2	-7.4	CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
MMP_RS05075		-1.2	-10.3	acetyl-CoA decarbonylase/synthase complex subunit gamma
MMP_RS07555		-1.2	-0.7	monovalent cation/H+ antiporter subunit E
MMP_RS07195		-1.2	-6.7	M20 family metallo-hydrolase
MMP_RS06105		-1.2	-6.1	hydrogenase maturation peptidase HycI
MMP_RS01610		-1.2	-3.1	hypothetical protein
MMP_RS05070		-1.2	-5.4	4Fe-4S dicluster domain-containing protein
MMP_RS06680		-1.2	-7.0	Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
MMP_RS07525		-1.2	-6.6	4Fe-4S binding protein
MMP_RS02240		-1.2	-3.2	methanogenesis marker 7 protein
MMP_RS03025		-1.2	-4.2	molybdenum cofactor guanylyltransferase
MMP_RS03600		-1.2	-1.8	triose-phosphate isomerase
MMP_RS08335		-1.2	-4.4	NADH-quinone oxidoreductase subunit B family protein
MMP_RS00735		-1.2	-3.2	5 10-methenyltetrahydromethanopterin hydrogenase
MMP_RS08105		-1.1	-5.0	6-carboxyhexanoate--CoA ligase
MMP_RS03145		-1.1	-5.1	fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
MMP_RS00685		-1.1	-3.3	2-phospho-L-lactate guanylyltransferase
MMP_RS06270		-1.1	-4.1	TIGR00300 family protein
MMP_RS06730		-1.1	-1.6	phosphopantothenate/pantothenate synthetase
MMP_RS06705		-1.1	-4.1	formate/nitrite transporter family protein
MMP_RS07185		-1.1	-7.7	pyridoxal phosphate-dependent aminotransferase
MMP_RS06625		-1.1	-1.7	DNA primase
MMP_RS01500		-1.1	-1.8	CBS domain-containing protein
MMP_RS08720		-1.1	-1.3	4Fe-4S binding protein
MMP_RS01720		-1.1	-1.9	replication factor C large subunit
MMP_RS03640		-1.1	-2.9	archaeal proteasome endopeptidase complex subunit beta
MMP_RS06345		-1.1	-5.1	formate dehydrogenase accessory sulfurtransferase FdhD
MMP_RS07750		-1.1	-2.9	DUF357 domain-containing protein
MMP_RS08820		-1.1	-3.3	hypothetical protein
MMP_RS06020		-1.1	-4.2	archaeoflavoprotein AfpA
MMP_RS02355		-1.1	-2.6	30S ribosomal protein S27ae
MMP_RS04875		-1.1	-3.2	energy-converting hydrogenase B subunit P
MMP_RS07445		-1.0	-3.4	helix-turn-helix domain-containing protein
MMP_RS03140		-1.0	-4.8	hypothetical protein
MMP_RS07380		-1.0	-1.7	transcription elongation factor Spt5
MMP_RS02245		-1.0	-2.7	hypothetical protein
MMP_RS03250		-1.0	-3.3	MJ1244 family protein
MMP_RS02800		-1.0	-4.0	nucleotidyltransferase domain-containing protein
MMP_RS04710		-1.0	-0.9	hypothetical protein
MMP_RS01800		-1.0	-3.2	TIGR00303 family protein
MMP_RS08240		-1.0	-5.9	methanogenesis marker 16 metalloprotein
MMP_RS00120		-1.0	-3.3	LysR family transcriptional regulator
MMP_RS05950		-1.0	-4.7	nickel-dependent hydrogenase large subunit
MMP_RS05875		-1.0	-2.6	hydroxyethylthiazole kinase
MMP_RS04720		-1.0	-1.6	DedA family protein
MMP_RS08760		-0.9	-2.2	hypothetical protein
MMP_RS07720		-0.9	-6.9	4Fe-4S binding protein
MMP_RS08345		-0.9	-6.7	4Fe-4S binding protein
MMP_RS05930		-0.9	-1.8	3-isopropylmalate dehydratase large subunit
MMP_RS01005		-0.9	-1.1	riboflavin synthase
MMP_RS00300		-0.9	-0.5	6 7-dimethyl-8-ribityllumazine synthase
MMP_RS03580		-0.9	-2.1	signal recognition particle-docking protein FtsY
MMP_RS03475		-0.9	-0.4	hypothetical protein
MMP_RS06290		-0.9	-3.2	DNA repair and recombination protein RadA
MMP_RS06685		-0.9	-5.4	formate dehydrogenase H subunit alpha selenocysteine-containing
MMP_RS02875		-0.9	-5.1	chorismate pyruvate-lyase family protein
MMP_RS00110		-0.9	-1.8	hypothetical protein
MMP_RS04775		-0.9	-2.2	adenosylhomocysteinase
MMP_RS08725		-0.9	-1.7	Ni/Fe hydrogenase subunit alpha
MMP_RS05975		-0.9	-1.2	hypothetical protein
MMP_RS00900		-0.9	-1.6	50S ribosomal protein L39e
MMP_RS01240		-0.9	-1.1	7-cyano-7-deazaguanine synthase QueC
MMP_RS00060		-0.9	-1.2	3-dehydroquinate synthase II
MMP_RS04685		-0.9	-2.3	DUF126 domain-containing protein
MMP_RS08355		-0.9	-4.1	Na(+)/H(+) antiporter subunit B
MMP_RS05920		-0.9	-0.5	50S ribosomal protein L37e
MMP_RS03700		-0.9	-4.7	sodium:proton antiporter
MMP_RS03445		-0.8	-0.7	methanogenesis marker 17 protein
MMP_RS01380		-0.8	-2.5	PHP domain-containing protein
MMP_RS01910		-0.8	-5.6	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
MMP_RS00895		-0.8	-2.4	hypothetical protein
MMP_RS06975		-0.8	-1.5	sulfide-dependent adenosine diphosphate thiazole synthase
MMP_RS06925		-0.8	-1.5	ribonuclease VapC4
MMP_RS08995		-0.8	-1.0	hypothetical protein
MMP_RS06865		-0.8	-1.6	HypC/HybG/HupF family hydrogenase formation chaperone
MMP_RS03435		-0.8	-1.1	ketol-acid reductoisomerase
MMP_RS08365		-0.8	-3.0	energy conserving hydrogenase EhbF
MMP_RS01795		-0.8	-0.6	methanogenesis marker 6 protein
MMP_RS02495		-0.8	-1.6	hypothetical protein
MMP_RS04780		-0.8	-1.8	ribonuclease P
MMP_RS01675		-0.7	-1.1	hypothetical protein
MMP_RS03400		-0.7	-1.7	archease
MMP_RS08370		-0.7	-0.4	cation:proton antiporter subunit C
MMP_RS08210		-0.7	-1.5	phosphatidylglycerophosphatase A
MMP_RS06630		-0.7	-0.6	UPF0058 family protein
MMP_RS08790		-0.7	-1.2	translation initiation factor IF-2 subunit alpha
MMP_RS01325		-0.7	-0.8	dihydroneopterin aldolase family protein
MMP_RS03555		-0.7	-3.5	transcriptional regulator
MMP_RS08445		-0.7	-1.5	DUF2099 family protein
MMP_RS03095		-0.7	-3.2	diphthine synthase
MMP_RS01250		-0.7	-2.7	tRNA (guanine(26)-N(2))-dimethyltransferase
MMP_RS01150		-0.7	-2.2	aldo/keto reductase
MMP_RS05445		-0.7	-2.8	CoB--CoM heterodisulfide reductase subunit B
MMP_RS05800		-0.7	-2.9	B12-binding domain-containing radical SAM protein
MMP_RS05925		-0.7	-2.1	small nuclear ribonucleoprotein
MMP_RS02190		-0.7	-1.6	sulfopyruvate decarboxylase subunit alpha
MMP_RS02145		-0.7	-3.0	winged helix-turn-helix transcriptional regulator
MMP_RS02130		-0.7	-2.8	zinc metalloprotease HtpX
MMP_RS07350		-0.7	-1.4	preprotein translocase subunit Sec61beta
MMP_RS05955		-0.7	-1.3	CoB--CoM heterodisulfide reductase subunit C
MMP_RS07200		-0.7	-3.0	[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
MMP_RS06840		-0.7	-0.6	DNA-directed RNA polymerase subunit N
MMP_RS00080		-0.7	-2.3	RecB-family nuclease
MMP_RS00345		-0.6	-1.7	DUF2666 domain-containing protein
MMP_RS00620		-0.6	-2.9	4Fe-4S binding protein
MMP_RS01260		-0.6	-1.1	HDIG domain-containing protein
MMP_RS04785		-0.6	-4.3	hypothetical protein
MMP_RS04420		-0.6	-2.6	LysE family translocator
MMP_RS06475		-0.6	-1.8	FAD-dependent oxidoreductase
MMP_RS08750		-0.6	-2.0	hypothetical protein
MMP_RS06930		-0.6	-3.8	MBL fold metallo-hydrolase
MMP_RS00720		-0.6	-2.6	metal-dependent hydrolase
MMP_RS01905		-0.6	-4.1	glycosyltransferase
MMP_RS02170		-0.6	-2.0	CBS domain-containing protein
MMP_RS00810		-0.6	-3.4	topoisomerase DNA-binding C4 zinc finger domain-containing protein
MMP_RS06885		-0.6	-0.8	50S ribosome-binding GTPase
MMP_RS01915		-0.6	-4.2	DUF354 domain-containing protein
MMP_RS00315		-0.6	-1.8	Nif3-like dinuclear metal center hexameric protein
MMP_RS08350		-0.6	-0.5	hypothetical protein
MMP_RS07355		-0.6	-0.5	transcription factor S

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments