Experiment set5IT018 for Methanococcus maripaludis S2

Compare to:

Formate with Bacitracin 15.6 uM

200 most important genes:

  gene name fitness t score description  
MMP_RS02280 -3.4 -0.9 DUF211 domain-containing protein compare
MMP_RS05555 -3.0 -1.1 DUF4040 domain-containing protein compare
MMP_RS06525 -2.3 -1.2 YciI family protein compare
MMP_RS02605 -2.3 -0.9 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS03300 -2.2 -0.8 TOBE domain-containing protein compare
MMP_RS05975 -2.1 -1.4 hypothetical protein compare
MMP_RS07425 -2.0 -4.3 GTP-binding protein compare
MMP_RS01240 -2.0 -1.7 7-cyano-7-deazaguanine synthase QueC compare
MMP_RS02805 -1.7 -1.0 HEPN domain-containing protein compare
MMP_RS06325 -1.7 -1.2 hypothetical protein compare
MMP_RS05315 -1.6 -1.7 hypothetical protein compare
MMP_RS00395 -1.4 -1.2 MGMT family protein compare
MMP_RS06760 -1.4 -2.6 hypothetical protein compare
MMP_RS07815 -1.4 -1.0 DUF2120 domain-containing protein compare
MMP_RS02745 -1.3 -1.7 hypothetical protein compare
MMP_RS03465 -1.3 -0.8 adenine phosphoribosyltransferase compare
MMP_RS03345 -1.3 -7.6 hypothetical protein compare
MMP_RS06870 -1.3 -4.0 DedA family protein compare
MMP_RS06840 -1.2 -0.7 DNA-directed RNA polymerase subunit N compare
MMP_RS04055 -1.2 -1.1 hypothetical protein compare
MMP_RS06340 -1.2 -4.0 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS07125 -1.2 -1.8 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS02720 -1.2 -2.2 molybdate ABC transporter substrate-binding protein compare
MMP_RS08370 -1.2 -0.4 cation:proton antiporter subunit C compare
MMP_RS02190 -1.1 -1.7 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS07840 -1.1 -2.0 ribonuclease III compare
MMP_RS03550 -1.1 -1.3 DUF2124 domain-containing protein compare
MMP_RS08860 -1.1 -2.7 MinD/ParA family protein compare
MMP_RS05140 -1.1 -2.3 helix-turn-helix transcriptional regulator compare
MMP_RS02765 -1.1 -3.4 ABC transporter ATP-binding protein compare
MMP_RS07880 -1.1 -4.1 AAA family ATPase compare
MMP_RS02755 -1.0 -4.8 ABC transporter permease compare
MMP_RS04145 -1.0 -1.0 hypothetical protein compare
MMP_RS01005 -1.0 -0.6 riboflavin synthase compare
MMP_RS07130 -1.0 -3.4 coenzyme F420 hydrogenase subunit gamma compare
MMP_RS03440 -0.9 -0.7 MoaD/ThiS family protein compare
MMP_RS07385 -0.9 -1.5 protein translocase SEC61 complex subunit gamma compare
MMP_RS06485 -0.9 -0.6 zinc ribbon domain-containing protein compare
MMP_RS02170 -0.9 -2.6 CBS domain-containing protein compare
MMP_RS08165 -0.9 -1.1 phosphoglycerate dehydrogenase compare
MMP_RS01335 -0.9 -1.0 prefoldin subunit beta compare
MMP_RS08235 -0.9 -2.7 hypothetical protein compare
MMP_RS06310 -0.9 -2.8 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS06335 -0.8 -2.2 HAD family hydrolase compare
MMP_RS05970 -0.8 -1.8 class II SORL domain-containing protein compare
MMP_RS00670 -0.8 -2.2 TIM barrel protein compare
MMP_RS02100 -0.8 -1.9 metallophosphoesterase compare
MMP_RS05430 -0.8 -2.9 TIGR00288 family NYN domain-containing protein compare
MMP_RS03910 -0.8 -0.9 hypothetical protein compare
MMP_RS06610 -0.8 -2.0 DUF2334 domain-containing protein compare
MMP_RS02175 -0.8 -0.4 DUF1611 domain-containing protein compare
MMP_RS07535 -0.8 -3.7 4Fe-4S binding protein compare
MMP_RS00900 -0.7 -0.7 50S ribosomal protein L39e compare
MMP_RS01260 -0.7 -2.1 HDIG domain-containing protein compare
MMP_RS01155 -0.7 -2.0 XRE family transcriptional regulator compare
MMP_RS00950 -0.7 -2.8 site-2 protease family protein compare
MMP_RS04015 -0.7 -1.3 hypothetical protein compare
MMP_RS07115 -0.7 -2.6 MBL fold metallo-hydrolase compare
MMP_RS07765 -0.7 -2.4 sodium:alanine symporter family protein compare
MMP_RS05815 -0.7 -0.7 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS05925 -0.7 -1.5 small nuclear ribonucleoprotein compare
MMP_RS07005 -0.7 -0.3 4Fe-4S binding protein compare
MMP_RS02230 -0.7 -3.0 sodium-dependent transporter compare
MMP_RS07350 -0.7 -0.6 preprotein translocase subunit Sec61beta compare
MMP_RS06900 -0.7 -1.2 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS06590 -0.7 -1.5 GNAT family N-acetyltransferase compare
MMP_RS00320 -0.7 -0.8 class I SAM-dependent methyltransferase compare
MMP_RS01650 -0.7 -0.5 sulfurtransferase TusA family protein compare
MMP_RS05795 -0.7 -1.7 redox-regulated ATPase YchF compare
MMP_RS02785 -0.6 -2.5 MarR family transcriptional regulator compare
MMP_RS03840 -0.6 -1.1 hypothetical protein compare
MMP_RS05965 -0.6 -1.4 carboxymuconolactone decarboxylase family protein compare
MMP_RS01020 -0.6 -0.4 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS06055 -0.6 -2.3 peroxiredoxin compare
MMP_RS01750 -0.6 -4.0 DUF63 family protein compare
MMP_RS07095 -0.6 -0.7 PspC domain-containing protein compare
MMP_RS02045 -0.6 -0.7 tRNA-Met compare
MMP_RS01380 -0.6 -1.3 PHP domain-containing protein compare
MMP_RS00315 -0.6 -2.4 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS01645 -0.6 -1.3 SWIM zinc finger family protein compare
MMP_RS01630 -0.6 -2.7 N-glycosylase/DNA lyase compare
MMP_RS05365 -0.6 -0.8 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH compare
MMP_RS00110 -0.6 -1.1 hypothetical protein compare
MMP_RS00570 -0.6 -0.8 protein-L-isoaspartate O-methyltransferase compare
MMP_RS05290 -0.6 -2.4 TetR/AcrR family transcriptional regulator compare
MMP_RS03585 -0.6 -1.3 Hsp20/alpha crystallin family protein compare
MMP_RS08430 -0.6 -2.1 HAD family hydrolase compare
MMP_RS07770 -0.6 -1.9 alanine racemase compare
MMP_RS07890 -0.6 -0.8 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS03575 -0.6 -3.0 ECF transporter S component compare
MMP_RS01570 -0.6 -0.6 hypothetical protein compare
MMP_RS07885 -0.6 -1.1 tripartite tricarboxylate transporter permease compare
MMP_RS02735 -0.6 -1.8 MBL fold metallo-hydrolase compare
MMP_RS07420 -0.6 -1.3 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS07725 -0.6 -1.4 4Fe-4S dicluster domain-containing protein compare
MMP_RS00290 -0.6 -1.6 hypothetical protein compare
MMP_RS07850 -0.6 -1.2 prephenate dehydratase compare
MMP_RS03305 -0.6 -1.8 winged helix-turn-helix domain-containing protein compare
MMP_RS06305 -0.5 -2.7 transporter substrate-binding domain-containing protein compare
MMP_RS06015 -0.5 -2.1 flavodoxin family protein compare
MMP_RS00125 -0.5 -0.6 DUF2798 domain-containing protein compare
MMP_RS00625 -0.5 -1.8 hypothetical protein compare
MMP_RS03795 -0.5 -2.8 YqhA family protein compare
MMP_RS06280 -0.5 -1.7 alpha-glucan family phosphorylase compare
MMP_RS03145 -0.5 -1.2 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS07135 -0.5 -2.6 coenzyme F420 hydrogenase subunit beta compare
MMP_RS07845 -0.5 -0.7 LL-diaminopimelate aminotransferase compare
MMP_RS08345 -0.5 -2.6 4Fe-4S binding protein compare
MMP_RS08380 -0.5 -1.6 phosphatase PAP2 family protein compare
MMP_RS07835 -0.5 -1.4 TldD/PmbA family protein compare
MMP_RS08995 -0.5 -0.5 hypothetical protein compare
MMP_RS00830 -0.5 -0.8 purine phosphoribosyltransferase family protein compare
MMP_RS08830 -0.5 -1.8 GTP-binding protein compare
MMP_RS04610 -0.5 -1.2 Dabb family protein compare
MMP_RS02760 -0.5 -2.7 COG1361 S-layer family protein compare
MMP_RS09050 -0.5 -1.2 CAP domain-containing protein compare
MMP_RS03335 -0.5 -1.7 ABC transporter permease compare
MMP_RS00105 -0.5 -2.3 hypothetical protein compare
MMP_RS08240 -0.5 -2.0 methanogenesis marker 16 metalloprotein compare
MMP_RS08250 -0.5 -2.1 pyruvate kinase compare
MMP_RS05765 -0.5 -1.3 M42 family metallopeptidase compare
MMP_RS04875 -0.5 -1.3 energy-converting hydrogenase B subunit P compare
MMP_RS05945 -0.5 -1.4 CBS domain-containing protein compare
MMP_RS07555 -0.5 -0.3 monovalent cation/H+ antiporter subunit E compare
MMP_RS04775 -0.5 -0.9 adenosylhomocysteinase compare
MMP_RS06660 -0.5 -2.0 glycosyltransferase family 4 protein compare
MMP_RS00140 -0.5 -1.7 DUF192 domain-containing protein compare
MMP_RS08395 -0.5 -1.8 DsrE family protein compare
MMP_RS08460 -0.5 -0.7 proteasome-activating nucleotidase compare
MMP_RS01195 -0.5 -0.4 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS06200 -0.5 -2.2 M24 family metallopeptidase compare
MMP_RS02200 -0.5 -2.6 methyl-accepting chemotaxis protein compare
MMP_RS06650 -0.4 -2.5 glycoside hydrolase family 57 protein compare
MMP_RS01660 -0.4 -1.1 hypothetical protein compare
MMP_RS06365 -0.4 -0.8 hypothetical protein compare
MMP_RS01100 -0.4 -0.5 ABC transporter ATP-binding protein compare
MMP_RS04405 -0.4 -1.7 hypothetical protein compare
MMP_RS08200 -0.4 -2.7 archaeosine synthase subunit alpha compare
MMP_RS02315 -0.4 -1.9 RimK family alpha-L-glutamate ligase compare
MMP_RS00335 -0.4 -1.3 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMP_RS06500 -0.4 -1.7 ATP-binding protein compare
MMP_RS03265 -0.4 -2.3 sugar phosphate isomerase/epimerase compare
MMP_RS04335 -0.4 -2.1 GTP-binding protein compare
MMP_RS08930 -0.4 -0.5 hypothetical protein compare
MMP_RS03420 -0.4 -0.7 acetolactate synthase small subunit compare
MMP_RS01785 -0.4 -2.0 hypothetical protein compare
MMP_RS06005 -0.4 -0.9 heavy-metal-associated domain-containing protein compare
MMP_RS08290 -0.4 -1.4 DNA-binding protein Alba compare
MMP_RS03220 -0.4 -0.5 RNA 2' 3'-cyclic phosphodiesterase compare
MMP_RS06170 -0.4 -1.3 ABC transporter ATP-binding protein compare
MMP_RS01675 -0.4 -0.5 hypothetical protein compare
MMP_RS02015 -0.4 -1.4 amidohydrolase compare
MMP_RS00990 -0.4 -1.0 hypothetical protein compare
MMP_RS02020 -0.4 -1.1 gamma-glutamylcyclotransferase compare
MMP_RS01030 -0.4 -1.1 MTAP family purine nucleoside phosphorylase compare
MMP_RS02815 -0.4 -0.4 hypothetical protein compare
MMP_RS05505 -0.4 -1.5 class IV adenylate cyclase compare
MMP_RS01225 -0.4 -0.7 DUF5379 domain-containing protein compare
MMP_RS03330 -0.4 -2.2 rubrerythrin family protein compare
MMP_RS08640 -0.4 -1.5 TIM barrel protein compare
MMP_RS07120 -0.4 -1.5 coenzyme F420 hydrogenase subunit alpha compare
MMP_RS02265 -0.4 -0.8 nitroreductase family protein compare
MMP_RS07530 -0.4 -1.6 4Fe-4S binding protein compare
MMP_RS05235 -0.4 -1.7 exodeoxyribonuclease III compare
MMP_RS05310 -0.4 -1.8 hypothetical protein compare
MMP_RS08990 -0.4 -1.4 hypothetical protein compare
MMP_RS08670 -0.4 -1.6 metallophosphoesterase compare
MMP_RS04840 -0.4 -1.9 response regulator compare
MMP_RS01280 -0.4 -1.9 DUF515 domain-containing protein compare
MMP_RS04595 -0.4 -1.2 hypothetical protein compare
MMP_RS08605 -0.4 -1.6 flagellar protein E compare
MMP_RS08535 -0.4 -1.8 bis-aminopropyl spermidine synthase family protein compare
MMP_RS03140 -0.4 -1.3 hypothetical protein compare
MMP_RS08655 -0.4 -2.0 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS07790 -0.4 -2.1 segregation/condensation protein A compare
MMP_RS08080 -0.4 -1.9 YchF/TatD family DNA exonuclease compare
MMP_RS06385 -0.4 -0.9 hypothetical protein compare
MMP_RS01255 -0.4 -1.3 amino acid ABC transporter ATP-binding protein compare
MMP_RS03520 -0.4 -0.4 YwbE family protein compare
MMP_RS07695 -0.4 -1.3 DUF3236 domain-containing protein compare
MMP_RS01990 -0.4 -0.9 hypothetical protein compare
MMP_RS05150 -0.4 -1.4 hypothetical protein compare
MMP_RS02960 -0.4 -1.6 class I SAM-dependent methyltransferase family protein compare
MMP_RS04030 -0.3 -1.2 hypothetical protein compare
MMP_RS02300 -0.3 -0.8 NAD(P)H-dependent oxidoreductase compare
MMP_RS02390 -0.3 -1.1 NifB/NifX family molybdenum-iron cluster-binding protein compare
MMP_RS01290 -0.3 -1.6 class III signal peptide-containing protein compare
MMP_RS01765 -0.3 -1.2 HIT family protein compare
MMP_RS00310 -0.3 -1.7 CBS domain-containing protein compare
MMP_RS08355 -0.3 -1.1 Na(+)/H(+) antiporter subunit B compare
MMP_RS03090 -0.3 -1.5 cation:proton antiporter compare
MMP_RS03685 -0.3 -1.2 Mrp/NBP35 family ATP-binding protein compare
MMP_RS02895 -0.3 -1.5 DHH family phosphoesterase compare
MMP_RS00705 -0.3 -0.6 hypothetical protein compare
MMP_RS01200 -0.3 -0.7 hypothetical protein compare
MMP_RS05280 -0.3 -1.7 COG1361 S-layer family protein compare
MMP_RS00730 -0.3 -0.9 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS01870 -0.3 -1.2 acyl-CoA dehydratase activase compare
MMP_RS08555 -0.3 -0.8 hypothetical protein compare
MMP_RS03410 -0.3 -1.6 hypothetical protein compare


Specific Phenotypes

For 2 genes in this experiment

For stress Bacitracin in Methanococcus maripaludis S2

For stress Bacitracin across organisms