Experiment set5IT018 for Klebsiella michiganensis M5al

Compare to:

D-Alanine carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS04160 -7.4 -7.2 phosphoserine phosphatase compare
BWI76_RS04670 -7.3 -7.1 3-isopropylmalate dehydratase large subunit compare
BWI76_RS26460 -7.0 -4.8 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS05840 -6.9 -4.8 glutamate 5-kinase compare
BWI76_RS20965 -6.9 -5.7 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS18920 -6.8 -4.7 ATP phosphoribosyltransferase compare
BWI76_RS04675 -6.8 -6.5 3-isopropylmalate dehydrogenase compare
BWI76_RS11965 -6.7 -5.6 orotidine-5'-phosphate decarboxylase compare
BWI76_RS04465 -6.7 -4.6 carbamoyl-phosphate synthase small subunit compare
BWI76_RS04250 -6.6 -7.8 homoserine kinase compare
BWI76_RS04685 -6.5 -8.9 putative leucine operon leader peptide compare
BWI76_RS18935 -6.5 -6.8 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS20270 -6.5 -7.7 hypothetical protein compare
BWI76_RS02815 -6.3 -4.4 fructose-bisphosphatase class I compare
BWI76_RS08395 -6.3 -2.6 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS18925 -6.2 -8.5 histidinol dehydrogenase compare
BWI76_RS11850 -6.2 -11.0 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS04645 -6.1 -7.2 3-dehydroquinase compare
BWI76_RS04470 -6.0 -10.1 carbamoyl phosphate synthase large subunit compare
BWI76_RS08385 -6.0 -3.4 citrate (Si)-synthase compare
BWI76_RS04680 -5.9 -12.5 2-isopropylmalate synthase compare
BWI76_RS09755 -5.9 -7.7 phosphoserine transaminase compare
BWI76_RS01615 -5.8 -11.2 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS23360 -5.8 -4.0 diaminopimelate decarboxylase compare
BWI76_RS00980 -5.8 -10.4 PLP-dependent threonine dehydratase compare
BWI76_RS00850 -5.7 -10.9 acetylglutamate kinase compare
BWI76_RS22240 -5.7 -6.3 transcriptional regulator compare
BWI76_RS18940 -5.7 -7.3 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS21265 -5.7 -13.2 phosphoribosylformylglycinamidine synthase compare
BWI76_RS26455 -5.6 -3.1 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS23365 -5.6 -6.6 LysR family transcriptional regulator compare
BWI76_RS07070 -5.6 -5.4 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS20355 -5.5 -3.7 colicin V production protein compare
BWI76_RS23920 -5.5 -6.5 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS26085 -5.5 -3.8 3-dehydroquinate synthase compare
BWI76_RS01655 -5.4 -8.9 homoserine O-succinyltransferase compare
BWI76_RS01210 -5.4 -4.3 tyrosine recombinase XerC compare
BWI76_RS04665 -5.3 -17.1 3-isopropylmalate dehydratase small subunit compare
BWI76_RS09910 -5.3 -18.0 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS21475 -5.2 -6.1 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS04245 -5.2 -14.6 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS01610 -5.2 -8.0 phosphoribosylamine--glycine ligase compare
BWI76_RS27475 -5.2 -11.0 regulatory protein GntR family protein compare
BWI76_RS05015 -5.1 -4.1 transcriptional regulator compare
BWI76_RS25115 -5.1 -7.0 argininosuccinate synthase compare
BWI76_RS09645 -5.1 -2.1 thioredoxin-disulfide reductase compare
BWI76_RS00990 -5.1 -7.3 ketol-acid reductoisomerase compare
BWI76_RS04705 -5.0 -6.8 DNA-binding transcriptional regulator FruR compare
BWI76_RS18950 -5.0 -3.9 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS04255 -4.9 -10.9 threonine synthase compare
BWI76_RS00805 -4.9 -5.4 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS23220 -4.8 -9.2 amino-acid N-acetyltransferase compare
BWI76_RS20895 -4.8 -6.6 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS27385 -4.8 -7.3 orotate phosphoribosyltransferase compare
BWI76_RS00835 -4.8 -15.0 phosphoenolpyruvate carboxylase compare
BWI76_RS07065 -4.7 -10.5 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS00855 -4.7 -7.3 argininosuccinate lyase compare
BWI76_RS00965 -4.7 -1.9 acetolactate synthase 2 small subunit compare
BWI76_RS03010 -4.6 -7.4 ornithine carbamoyltransferase compare
BWI76_RS05835 -4.5 -2.8 gamma-glutamyl-phosphate reductase compare
BWI76_RS00140 -4.5 -1.8 phosphate transport system regulator PhoU compare
BWI76_RS08205 -4.5 -5.6 DNA-binding transcriptional dual regulator NagC compare
BWI76_RS02700 -4.4 -11.0 D-serine/D-alanine/glycine transporter conserved
BWI76_RS18955 -4.3 -5.3 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS11840 -4.3 -6.5 tryptophan synthase subunit alpha compare
BWI76_RS18930 -4.3 -8.1 histidinol-phosphate transaminase compare
BWI76_RS03080 -4.3 -4.1 (Fe-S)-cluster assembly protein compare
BWI76_RS26570 -4.3 -4.1 anion permease compare
BWI76_RS11855 -4.2 -9.3 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS20350 -4.2 -6.8 amidophosphoribosyltransferase compare
BWI76_RS25420 -4.2 -9.3 malate dehydrogenase compare
BWI76_RS26175 -4.2 -6.3 DeoR/GlpR family transcriptional regulator compare
BWI76_RS11860 -4.1 -8.1 anthranilate synthase component I compare
BWI76_RS24900 -4.1 -2.8 DeoR family transcriptional regulator compare
BWI76_RS27170 -4.1 -6.6 MltR family transcriptional regulator compare
BWI76_RS08405 -4.1 -3.3 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS02995 -4.1 -6.0 aspartate carbamoyltransferase compare
BWI76_RS09760 -4.1 -3.1 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS09660 -4.0 -2.7 DNA translocase FtsK compare
BWI76_RS05120 -4.0 -8.7 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS17720 -4.0 -2.3 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS00845 -4.0 -9.4 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS11845 -4.0 -3.2 tryptophan synthase subunit beta compare
BWI76_RS10990 -4.0 -2.5 dihydroorotase compare
BWI76_RS24285 -3.9 -8.6 cystathionine beta-lyase compare
BWI76_RS00975 -3.9 -6.4 dihydroxy-acid dehydratase compare
BWI76_RS03415 -3.9 -5.3 LacI family transcriptional regulator compare
BWI76_RS27390 -3.8 -4.8 ribonuclease PH compare
BWI76_RS17735 -3.8 -6.8 D-amino acid dehydrogenase small subunit conserved
BWI76_RS20435 -3.8 -2.2 chorismate synthase compare
BWI76_RS05200 -3.7 -3.6 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS21465 -3.7 -4.3 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS17065 -3.6 -8.2 phosphoenolpyruvate synthase compare
BWI76_RS00785 -3.6 -6.2 cystathionine gamma-synthase compare
BWI76_RS06495 -3.5 -9.1 cytochrome ubiquinol oxidase subunit II compare
BWI76_RS08520 -3.5 -4.1 colicin transporter TolQ compare
BWI76_RS06730 -3.5 -3.9 lac repressor compare
BWI76_RS06485 -3.5 -3.0 cytochrome o ubiquinol oxidase subunit III compare
BWI76_RS00400 -3.4 -2.2 glutamine synthetase compare
BWI76_RS09640 -3.4 -5.4 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD compare
BWI76_RS02970 -3.4 -6.7 trehalose operon repressor compare
BWI76_RS23240 -3.4 -4.0 exonuclease V subunit gamma compare
BWI76_RS22765 -3.4 -12.9 sulfite reductase subunit alpha compare
BWI76_RS22420 -3.4 -3.8 LacI family transcriptional regulator compare
BWI76_RS06525 -3.4 -5.5 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS23230 -3.3 -2.3 exodeoxyribonuclease V subunit beta compare
BWI76_RS22755 -3.3 -5.9 phosphoadenosine phosphosulfate reductase compare
BWI76_RS00180 -3.2 -2.4 F0F1 ATP synthase subunit epsilon compare
BWI76_RS01185 -3.2 -2.2 adenylate cyclase compare
BWI76_RS08210 -3.2 -2.3 N-acetylglucosamine-6-phosphate deacetylase compare
BWI76_RS06185 -3.0 -6.2 shikimate kinase II compare
BWI76_RS02410 -3.0 -2.0 EF-P beta-lysylation protein EpmB compare
BWI76_RS20650 -2.9 -2.0 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS04240 -2.9 -1.7 thr operon leader peptide compare
BWI76_RS00240 -2.9 -3.3 FMN-binding protein MioC compare
BWI76_RS07675 -2.9 -4.4 DeoR family transcriptional regulator compare
BWI76_RS20640 -2.8 -6.7 cysteine synthase A compare
BWI76_RS22690 -2.8 -2.7 adenylyl-sulfate kinase compare
BWI76_RS00985 -2.7 -6.1 transcriptional regulator IlvY compare
BWI76_RS15825 -2.7 -2.3 hypothetical protein compare
BWI76_RS11155 -2.7 -1.7 penicillin-binding protein activator LpoB compare
BWI76_RS08425 -2.6 -5.2 succinyl-CoA ligase subunit beta compare
BWI76_RS01800 -2.5 -3.8 glucose-6-phosphate isomerase compare
BWI76_RS02735 -2.5 -3.8 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS27430 -2.5 -2.0 (p)ppGpp synthetase compare
BWI76_RS22760 -2.5 -7.0 sulfite reductase subunit beta compare
BWI76_RS23915 -2.5 -2.8 5-formyltetrahydrofolate cyclo-ligase compare
BWI76_RS24850 -2.5 -9.1 DeoR family transcriptional regulator compare
BWI76_RS02610 -2.4 -6.9 transcriptional regulator compare
BWI76_RS03225 -2.4 -9.6 transcriptional regulator compare
BWI76_RS07120 -2.4 -9.1 LacI family transcriptional regulator compare
BWI76_RS08430 -2.3 -6.4 succinate--CoA ligase subunit alpha compare
BWI76_RS20995 -2.3 -4.9 RNA degradosome polyphosphate kinase compare
BWI76_RS07435 -2.3 -5.6 LacI family transcriptional regulator compare
BWI76_RS01205 -2.2 -2.5 DUF484 family protein compare
BWI76_RS26055 -2.2 -7.7 siroheme synthase compare
BWI76_RS06490 -2.2 -5.9 cytochrome ubiquinol oxidase subunit I compare
BWI76_RS23355 -2.2 -3.8 LacI family transcriptional regulator compare
BWI76_RS01200 -2.2 -2.9 diaminopimelate epimerase compare
BWI76_RS27075 -2.2 -5.0 IclR family transcriptional regulator compare
BWI76_RS21100 -2.2 -3.8 nucleoside-diphosphate kinase compare
BWI76_RS26940 -2.1 -8.2 transcriptional regulator compare
BWI76_RS09615 -2.1 -2.6 ATP-dependent Clp protease ATP-binding subunit ClpA compare
BWI76_RS06530 -2.1 -5.7 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS01115 -2.1 -3.4 dTDP-4-amino-4,6-dideoxygalactose transaminase compare
BWI76_RS01110 -2.1 -3.7 TDP-fucosamine acetyltransferase compare
BWI76_RS26890 -2.1 -2.0 hypothetical protein compare
BWI76_RS23830 -2.0 -6.3 hypothetical protein compare
BWI76_RS08530 -2.0 -3.3 protein TolA compare
BWI76_RS25335 -2.0 -1.8 stringent starvation protein A compare
BWI76_RS01125 -2.0 -5.6 4-alpha-L-fucosyltransferase compare
BWI76_RS23885 -1.9 -2.3 2-octaprenylphenol hydroxylase compare
BWI76_RS06535 -1.9 -4.3 endopeptidase La compare
BWI76_RS04510 -1.9 -2.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS08215 -1.8 -5.0 glucosamine-6-phosphate deaminase compare
BWI76_RS09635 -1.8 -3.4 amino acid ABC transporter ATP-binding protein compare
BWI76_RS19705 -1.8 -2.9 kinase compare
BWI76_RS26245 -1.8 -3.5 transcriptional regulator compare
BWI76_RS16235 -1.7 -4.6 membrane protein compare
BWI76_RS13575 -1.7 -5.8 sugar binding transcriptional regulator, LacI family protein compare
BWI76_RS06475 -1.7 -1.6 protoheme IX farnesyltransferase compare
BWI76_RS15955 -1.7 -7.2 transcriptional regulator compare
BWI76_RS02985 -1.7 -3.5 reactive intermediate/imine deaminase compare
BWI76_RS25060 -1.7 -3.2 lipoprotein NlpI compare
BWI76_RS02530 -1.7 -2.1 tRNA dimethylallyltransferase compare
BWI76_RS08535 -1.7 -1.5 translocation protein TolB compare
BWI76_RS05680 -1.7 -4.2 LacI family transcriptional regulator compare
BWI76_RS25600 -1.7 -1.3 tRNA-Thr compare
BWI76_RS15835 -1.6 -1.1 hypothetical protein compare
BWI76_RS07305 -1.6 -4.2 sucrose operon repressor compare
BWI76_RS23420 -1.6 -8.1 LacI family transcriptional regulator compare
BWI76_RS21140 -1.6 -2.4 molecular chaperone HscA compare
BWI76_RS20440 -1.6 -1.6 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS20160 -1.6 -2.5 NADH-quinone oxidoreductase subunit H compare
BWI76_RS23480 -1.6 -8.3 EAL domain-containing protein compare
BWI76_RS07820 -1.6 -2.5 S-methyl-5-thioribose kinase compare
BWI76_RS00345 -1.5 -3.4 protein disulfide oxidoreductase DsbA compare
BWI76_RS04530 -1.5 -1.5 peptidylprolyl isomerase SurA compare
BWI76_RS08525 -1.5 -2.9 colicin transporter compare
BWI76_RS25645 -1.5 -5.8 shikimate dehydrogenase compare
BWI76_RS16360 -1.5 -1.8 electron transport complex subunit RsxB compare
BWI76_RS26405 -1.5 -1.3 16S rRNA (guanine(966)-N(2))-methyltransferase compare
BWI76_RS00600 -1.4 -5.0 LacI family transcriptional regulator compare
BWI76_RS24740 -1.4 -2.9 GntR family transcriptional regulator compare
BWI76_RS20190 -1.4 -6.3 NADH-quinone oxidoreductase subunit A compare
BWI76_RS14075 -1.4 -2.0 TetR family transcriptional regulator compare
BWI76_RS03880 -1.4 -3.3 homoprotocatechuate degradation operon regulator, HpaR compare
BWI76_RS26620 -1.4 -1.3 Fe-S biogenesis protein NfuA compare
BWI76_RS25065 -1.4 -2.5 polyribonucleotide nucleotidyltransferase compare
BWI76_RS00065 -1.4 -3.9 MurR/RpiR family transcriptional regulator compare
BWI76_RS24605 -1.4 -7.3 dihydroxyacetone kinase subunit DhaM compare
BWI76_RS01135 -1.4 -3.4 lipopolysaccharide N-acetylmannosaminouronosyltransferase compare
BWI76_RS08390 -1.4 -1.8 hypothetical protein compare
BWI76_RS20135 -1.3 -3.7 NADH-quinone oxidoreductase subunit M compare
BWI76_RS22805 -1.3 -5.2 GTP diphosphokinase compare
BWI76_RS20130 -1.3 -5.1 NADH-quinone oxidoreductase subunit N compare
BWI76_RS25870 -1.3 -1.7 elongation factor Tu compare
BWI76_RS17300 -1.3 -1.6 tRNA-Tyr compare
BWI76_RS24635 -1.3 -2.3 autoinducer-2 (AI-2) modifying protein LsrG compare
BWI76_RS26310 -1.3 -7.0 IclR family transcriptional regulator compare


Specific Phenotypes

For 7 genes in this experiment

For carbon source D-Alanine in Klebsiella michiganensis M5al

For carbon source D-Alanine across organisms