Experiment set5IT018 for Klebsiella michiganensis M5al

Compare to:

D-Alanine carbon source

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS24575 +2.5 4.0 hypothetical protein compare
BWI76_RS01585 +1.4 8.6 transcriptional regulator compare
BWI76_RS15015 +1.3 2.2 DUF2132 domain-containing protein compare
BWI76_RS04305 +1.2 1.2 molecular chaperone DnaJ compare
BWI76_RS19770 +1.2 2.0 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase compare
BWI76_RS20750 +1.1 1.8 carboxysome structural protein EutK compare
BWI76_RS11700 +1.1 1.8 hypothetical protein compare
BWI76_RS18770 +1.1 1.5 DNA gyrase inhibitor compare
BWI76_RS18060 +1.1 2.0 hypothetical protein compare
BWI76_RS11010 +1.0 3.9 30S ribosomal protein S5 alanine N-acetyltransferase compare
BWI76_RS25285 +1.0 1.3 HPr family phosphocarrier protein compare
BWI76_RS00715 +1.0 3.6 two-component sensor histidine kinase compare
BWI76_RS21565 +1.0 1.6 outer membrane protein assembly factor BamE compare
BWI76_RS10060 +1.0 2.0 acylphosphatase compare
BWI76_RS15940 +1.0 3.1 DMSO reductase maturation protein DsmD compare
BWI76_RS10735 +1.0 2.7 hypothetical protein compare
BWI76_RS01540 +1.0 1.7 thiamine biosynthesis protein ThiS compare
BWI76_RS22935 +1.0 1.1 L-fucose mutarotase compare
BWI76_RS03105 +0.9 1.4 myo-inosose-2 dehydratase compare
BWI76_RS09655 +0.9 3.7 leucine-responsive regulatory protein compare
BWI76_RS05555 +0.9 3.3 Crl family RNA polymerase assembly factor compare
BWI76_RS16485 +0.9 1.9 ribonuclease T compare
BWI76_RS20720 +0.9 0.9 hypothetical protein compare
BWI76_RS15295 +0.9 4.6 MDR efflux pump AcrAB transcriptional activator MarA compare
BWI76_RS03665 +0.9 1.9 ABC transporter ATP-binding protein compare
BWI76_RS12585 +0.9 3.4 transcriptional regulator compare
BWI76_RS08380 +0.9 1.5 endonuclease VIII compare
BWI76_RS06075 +0.8 2.6 taurine transporter subunit compare
BWI76_RS00720 +0.8 1.9 DNA-binding response regulator compare
BWI76_RS03045 +0.8 1.2 hypothetical protein compare
BWI76_RS19835 +0.8 2.5 nucleoid-associated protein YejK compare
BWI76_RS00740 +0.8 2.5 ribonuclease E activity regulator RraA compare
BWI76_RS16895 +0.8 1.7 3-(3-hydroxy-phenyl)propionate transporter MhpT compare
BWI76_RS06540 +0.8 2.0 DNA-binding protein HU-beta compare
BWI76_RS25375 +0.8 2.5 hypothetical protein compare
BWI76_RS18230 +0.7 1.8 trehalose-6-phosphate synthase compare
BWI76_RS06740 +0.7 2.7 50S ribosomal protein L36 compare
BWI76_RS06130 +0.7 1.6 extensin family protein compare
BWI76_RS06665 +0.7 1.6 membrane protein compare
BWI76_RS07645 +0.7 1.6 short-chain dehydrogenase/reductase compare
BWI76_RS23745 +0.7 2.4 arsenate reductase compare
BWI76_RS01995 +0.7 1.0 AraC family transcriptional regulator compare
BWI76_RS16935 +0.7 1.1 shikimate dehydrogenase compare
BWI76_RS17350 +0.7 2.2 DNA-binding response regulator compare
BWI76_RS13175 +0.7 2.1 NodT family RND efflux system outer membrane lipoprotein compare
BWI76_RS20230 +0.7 0.8 hypothetical protein compare
BWI76_RS18810 +0.7 1.9 nitrogenase iron protein compare
BWI76_RS16015 +0.7 2.2 pheromone autoinducer 2 transporter compare
BWI76_RS24385 +0.7 4.4 phosphodiesterase compare
BWI76_RS11435 +0.7 1.0 hypothetical protein compare
BWI76_RS05465 +0.7 1.1 amidohydrolase compare
BWI76_RS01580 +0.7 1.9 hypothetical protein compare
BWI76_RS13135 +0.7 1.9 3-oxoadipyl-CoA thiolase compare
BWI76_RS05785 +0.7 2.7 CI repressor compare
BWI76_RS06405 +0.7 1.1 2-dehydropantoate 2-reductase compare
BWI76_RS08840 +0.7 1.5 hypothetical protein compare
BWI76_RS17945 +0.7 1.0 hypothetical protein compare
BWI76_RS06630 +0.7 1.4 hypothetical protein compare
BWI76_RS03610 +0.7 2.1 hypothetical protein compare
BWI76_RS00440 +0.7 1.3 CopG family transcriptional regulator compare
BWI76_RS05235 +0.7 1.1 hypothetical protein compare
BWI76_RS24885 +0.7 1.0 PTS galactitol transporter subunit IIB compare
BWI76_RS13785 +0.7 1.8 ABC transporter permease compare
BWI76_RS16785 +0.7 1.9 peptidase M20 compare
BWI76_RS05500 +0.6 2.5 NADH:ubiquinone reductase (Na(+)-transporting) subunit C compare
BWI76_RS25915 +0.6 1.4 protein SlyX compare
BWI76_RS25865 +0.6 2.6 ferredoxin compare
BWI76_RS08765 +0.6 1.4 8-amino-7-oxononanoate synthase compare
BWI76_RS09080 +0.6 2.1 molybdopterin-synthase adenylyltransferase MoeB compare
BWI76_RS07855 +0.6 1.4 PucR family transcriptional regulator compare
BWI76_RS26285 +0.6 2.5 glycerophosphodiester phosphodiesterase compare
BWI76_RS13685 +0.6 1.8 IclR family transcriptional regulator compare
BWI76_RS09490 +0.6 1.5 DNA-binding response regulator compare
BWI76_RS17890 +0.6 2.5 PTS mannose transporter subunit EIIAB compare
BWI76_RS09650 +0.6 4.0 hypothetical protein compare
BWI76_RS00655 +0.6 2.4 inner-membrane translocator compare
BWI76_RS07895 +0.6 1.9 sugar ABC transporter ATPase compare
BWI76_RS12170 +0.6 1.7 hypothetical protein compare
BWI76_RS08275 +0.6 1.1 LexA regulated protein compare
BWI76_RS25435 +0.6 2.8 membrane protein compare
BWI76_RS07730 +0.6 1.1 iron-enterobactin transporter membrane protein compare
BWI76_RS09860 +0.6 2.4 hypothetical protein compare
BWI76_RS27860 +0.6 3.7 D-serine dehydratase compare
BWI76_RS27670 +0.6 1.7 LysR family transcriptional regulator compare
BWI76_RS16075 +0.6 1.0 oxidoreductase compare
BWI76_RS26575 +0.6 2.0 universal stress protein B compare
BWI76_RS11775 +0.6 1.6 2-deoxy-D-gluconate 3-dehydrogenase compare
BWI76_RS21040 +0.6 3.1 peptidase M4 compare
BWI76_RS16920 +0.6 1.0 3-(2,3-dihydroxyphenyl)propionate dioxygenase compare
BWI76_RS11920 +0.6 2.5 hypothetical protein compare
BWI76_RS27865 +0.6 1.7 hypothetical protein compare
BWI76_RS14980 +0.6 1.4 hypothetical protein compare
BWI76_RS21190 +0.6 3.1 stationary phase inducible protein CsiE compare
BWI76_RS06445 +0.6 3.5 FAD-dependent oxidoreductase compare
BWI76_RS20925 +0.6 2.1 peptidase M48 compare
BWI76_RS27780 +0.6 1.2 hypothetical protein compare
BWI76_RS02825 +0.6 2.7 putative acyltransferase domain protein compare
BWI76_RS24180 +0.6 0.8 hypothetical protein compare
BWI76_RS16900 +0.6 1.4 4-hydroxy-2-oxovalerate aldolase compare
BWI76_RS16325 +0.6 2.6 adenosine deaminase compare
BWI76_RS03025 +0.6 1.6 N-acetyltransferase compare
BWI76_RS15445 +0.6 1.8 hypothetical protein compare
BWI76_RS13755 +0.5 1.4 hypothetical protein compare
BWI76_RS20795 +0.5 0.7 ethanolamine catabolic microcompartment shell protein EutN compare
BWI76_RS12790 +0.5 0.9 lactate dehydrogenase compare
BWI76_RS11170 +0.5 0.9 hypothetical protein compare
BWI76_RS15150 +0.5 1.9 outer membrane efflux protein compare
BWI76_RS08330 +0.5 1.0 hypothetical protein compare
BWI76_RS10575 +0.5 0.9 polar amino acid ABC transporter permease compare
BWI76_RS14510 +0.5 1.1 MFS transporter compare
BWI76_RS19865 +0.5 0.8 ecotin compare
BWI76_RS10840 +0.5 1.7 membrane protein compare
BWI76_RS06165 +0.5 2.2 phosphate starvation-inducible protein PsiF compare
BWI76_RS11380 +0.5 2.2 iron-dicitrate transporter substrate-binding subunit compare
BWI76_RS03180 +0.5 1.8 phage transcriptional regulator, AlpA compare
BWI76_RS26010 +0.5 2.5 cell filamentation protein Fic compare
BWI76_RS07705 +0.5 1.4 enterochelin esterase compare
BWI76_RS23710 +0.5 1.4 3-keto-2-deoxy-D-ribonyl-CoA thiolase (from data) compare
BWI76_RS14155 +0.5 1.2 transketolase compare
BWI76_RS00090 +0.5 2.6 multidrug transporter subunit MdtL compare
BWI76_RS20610 +0.5 2.0 LysR family transcriptional regulator compare
BWI76_RS14005 +0.5 1.1 TetR family transcriptional regulator compare
BWI76_RS06285 +0.5 2.5 peroxiredoxin compare
BWI76_RS20290 +0.5 1.7 thiol:disulfide oxidoreductase compare
BWI76_RS10275 +0.5 1.8 ABC transporter compare
BWI76_RS12860 +0.5 0.8 hypothetical protein compare
BWI76_RS18335 +0.5 3.5 DNA-binding response regulator compare
BWI76_RS18270 +0.5 1.4 hypothetical protein compare
BWI76_RS08315 +0.5 1.3 K+-transporting ATPase subunit B compare
BWI76_RS14840 +0.5 2.5 hypothetical protein compare
BWI76_RS11390 +0.5 1.6 iron dicitrate transport regulator FecR compare
BWI76_RS21105 +0.5 2.6 penicillin-binding protein 1C compare
BWI76_RS06680 +0.5 0.7 hypothetical protein compare
BWI76_RS15440 +0.5 1.4 hypothetical protein compare
BWI76_RS01595 +0.5 1.3 zinc resistance protein compare
BWI76_RS16370 +0.5 2.7 electron transport complex subunit D compare
BWI76_RS24470 +0.5 2.7 hypothetical protein compare
BWI76_RS08640 +0.5 1.1 multidrug efflux pump-associated protein, AcrZ family compare
BWI76_RS13960 +0.5 0.8 urea ABC transporter periplasmic protein compare
BWI76_RS13560 +0.5 0.7 amino acid ABC transporter substrate-binding subunit compare
BWI76_RS23970 +0.5 1.6 mechanosensitive ion channel protein MscS compare
BWI76_RS09765 +0.5 1.4 metalloprotease compare
BWI76_RS04600 +0.5 1.2 inner membrane protein compare
BWI76_RS12610 +0.5 1.2 LysR family transcriptional regulator compare
BWI76_RS23535 +0.5 0.9 hypothetical protein compare
BWI76_RS26630 +0.5 2.1 pimeloyl-[acyl-carrier protein] methyl ester esterase compare
BWI76_RS08705 +0.5 2.3 putative LuxR family regulatory protein compare
BWI76_RS19405 +0.5 1.1 LysR family transcriptional regulator compare
BWI76_RS21715 +0.5 1.2 transcriptional regulator compare
BWI76_RS01010 +0.5 1.8 uridine phosphorylase compare
BWI76_RS14850 +0.5 1.8 LacI family transcriptional regulator compare
BWI76_RS16120 +0.5 1.0 4-carboxymuconolactone decarboxylase compare
BWI76_RS15350 +0.5 0.9 hypothetical protein compare
BWI76_RS00560 +0.5 1.0 hypothetical protein compare
BWI76_RS14575 +0.5 1.0 TENA/THI-4 family protein compare
BWI76_RS01290 +0.5 1.6 putative dienelactone hydrolase compare
BWI76_RS17930 +0.5 1.7 cold-shock protein CspC compare
BWI76_RS07860 +0.5 1.6 cytosine permease compare
BWI76_RS06435 +0.5 1.5 MFS transporter compare
BWI76_RS06545 +0.5 1.5 peptidylprolyl isomerase compare
BWI76_RS15985 +0.5 2.5 LysR family transcriptional regulator compare
BWI76_RS27395 +0.5 1.1 hypothetical protein compare
BWI76_RS10570 +0.5 1.5 cysteine ABC transporter substrate-binding protein compare
BWI76_RS01270 +0.5 2.1 hypothetical protein compare
BWI76_RS18300 +0.5 1.4 hypothetical protein compare
BWI76_RS19240 +0.5 1.0 ABC transporter substrate-binding protein compare
BWI76_RS23040 +0.5 2.1 sirohydrochlorin cobaltochelatase compare
BWI76_RS08955 +0.5 2.4 23S rRNA (adenine(1618)-N(6))-methyltransferase compare
BWI76_RS26170 +0.5 2.5 transcriptional regulator MalT compare
BWI76_RS20430 +0.5 1.2 penicillin-insensitive murein endopeptidase compare
BWI76_RS08735 +0.5 1.7 Urocanate hydratase (EC 4.2.1.49) (from data) compare
BWI76_RS19575 +0.5 1.3 maleylacetoacetate isomerase compare
BWI76_RS24240 +0.4 1.0 hypothetical protein compare
BWI76_RS24405 +0.4 2.0 hypothetical protein compare
BWI76_RS16165 +0.4 1.3 peptidase M20 compare
BWI76_RS27565 +0.4 2.3 sugar aldolase compare
BWI76_RS16905 +0.4 2.0 acetaldehyde dehydrogenase (acetylating) compare
BWI76_RS08625 +0.4 1.7 UDP-glucose 4-epimerase GalE compare
BWI76_RS06205 +0.4 1.7 recombination-associated protein RdgC compare
BWI76_RS13150 +0.4 1.2 carnitine operon protein CaiE compare
BWI76_RS15240 +0.4 1.8 alcohol dehydrogenase compare
BWI76_RS17310 +0.4 1.7 AsnC family transcriptional regulator compare
BWI76_RS26020 +0.4 2.4 peptidylprolyl isomerase A compare
BWI76_RS23690 +0.4 0.6 putative glyoxalase/bleomycin resistance protein/dioxygenase compare
BWI76_RS23000 +0.4 1.0 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase compare
BWI76_RS25000 +0.4 0.5 malonate decarboxylase acyl carrier protein compare
BWI76_RS06120 +0.4 1.1 membrane protein compare
BWI76_RS12215 +0.4 1.4 HNH endonuclease compare
BWI76_RS24065 +0.4 1.3 deoxyribonuclease I compare
BWI76_RS06470 +0.4 1.0 hypothetical protein compare
BWI76_RS09065 +0.4 1.6 sugar phosphatase SupH compare
BWI76_RS01935 +0.4 0.6 thiamin phosphate synthase compare
BWI76_RS09695 +0.4 1.8 MFS transporter compare
BWI76_RS11520 +0.4 0.6 hypothetical protein compare
BWI76_RS19470 +0.4 1.1 DNA-binding response regulator compare
BWI76_RS07865 +0.4 1.4 methylthioribulose 1-phosphate dehydratase compare
BWI76_RS21905 +0.4 1.6 class II aldolase compare
BWI76_RS01560 +0.4 1.5 Rsd/AlgQ family anti-sigma factor compare
BWI76_RS17520 +0.4 2.3 carbamate kinase compare
BWI76_RS15000 +0.4 1.6 amino acid ABC transporter ATP-binding protein compare


Specific Phenotypes

For 7 genes in this experiment

For carbon source D-Alanine in Klebsiella michiganensis M5al

For carbon source D-Alanine across organisms