Experiment set5IT017 for Klebsiella michiganensis M5al

Compare to:

D-Serine carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS18930 -9.2 -6.3 histidinol-phosphate transaminase compare
BWI76_RS01210 -7.5 -5.2 tyrosine recombinase XerC compare
BWI76_RS00990 -7.1 -6.9 ketol-acid reductoisomerase compare
BWI76_RS18920 -6.8 -4.7 ATP phosphoribosyltransferase compare
BWI76_RS18950 -6.6 -6.4 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS02815 -6.4 -4.4 fructose-bisphosphatase class I compare
BWI76_RS21475 -6.4 -6.8 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS04250 -6.3 -8.6 homoserine kinase compare
BWI76_RS05840 -6.3 -6.1 glutamate 5-kinase compare
BWI76_RS21465 -6.2 -6.0 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS18935 -6.1 -6.4 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS00785 -6.1 -4.2 cystathionine gamma-synthase compare
BWI76_RS04645 -6.0 -7.1 3-dehydroquinase compare
BWI76_RS08385 -6.0 -3.5 citrate (Si)-synthase compare
BWI76_RS04665 -5.8 -20.3 3-isopropylmalate dehydratase small subunit compare
BWI76_RS00805 -5.8 -6.2 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS18940 -5.8 -6.8 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS20895 -5.7 -5.9 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS04470 -5.7 -10.3 carbamoyl phosphate synthase large subunit compare
BWI76_RS04670 -5.7 -10.9 3-isopropylmalate dehydratase large subunit compare
BWI76_RS04680 -5.7 -13.5 2-isopropylmalate synthase compare
BWI76_RS26085 -5.6 -3.8 3-dehydroquinate synthase compare
BWI76_RS20965 -5.5 -4.7 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS17720 -5.5 -2.3 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS04255 -5.4 -10.4 threonine synthase compare
BWI76_RS11860 -5.3 -9.3 anthranilate synthase component I compare
BWI76_RS26460 -5.3 -7.2 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS11850 -5.2 -9.1 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS17065 -5.2 -10.1 phosphoenolpyruvate synthase compare
BWI76_RS01615 -5.1 -12.4 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS09645 -5.1 -2.1 thioredoxin-disulfide reductase compare
BWI76_RS00850 -5.1 -7.6 acetylglutamate kinase compare
BWI76_RS09755 -5.1 -7.6 phosphoserine transaminase compare
BWI76_RS04675 -5.1 -5.9 3-isopropylmalate dehydrogenase compare
BWI76_RS23220 -5.0 -9.6 amino-acid N-acetyltransferase compare
BWI76_RS18955 -5.0 -7.6 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS04685 -4.9 -8.9 putative leucine operon leader peptide compare
BWI76_RS10990 -4.9 -4.7 dihydroorotase compare
BWI76_RS04465 -4.9 -5.2 carbamoyl-phosphate synthase small subunit compare
BWI76_RS22755 -4.8 -7.2 phosphoadenosine phosphosulfate reductase compare
BWI76_RS23360 -4.8 -5.7 diaminopimelate decarboxylase compare
BWI76_RS05835 -4.8 -4.0 gamma-glutamyl-phosphate reductase compare
BWI76_RS18925 -4.8 -6.3 histidinol dehydrogenase compare
BWI76_RS25115 -4.7 -9.0 argininosuccinate synthase compare
BWI76_RS20355 -4.7 -4.6 colicin V production protein compare
BWI76_RS04245 -4.7 -14.7 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS00975 -4.7 -8.4 dihydroxy-acid dehydratase compare
BWI76_RS11855 -4.7 -8.9 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS01655 -4.6 -7.7 homoserine O-succinyltransferase compare
BWI76_RS03010 -4.6 -7.6 ornithine carbamoyltransferase compare
BWI76_RS21265 -4.4 -15.7 phosphoribosylformylglycinamidine synthase compare
BWI76_RS11965 -4.4 -5.4 orotidine-5'-phosphate decarboxylase compare
BWI76_RS11840 -4.3 -6.6 tryptophan synthase subunit alpha compare
BWI76_RS00855 -4.3 -7.6 argininosuccinate lyase compare
BWI76_RS27385 -4.3 -7.2 orotate phosphoribosyltransferase compare
BWI76_RS04240 -4.3 -2.0 thr operon leader peptide compare
BWI76_RS09760 -4.2 -5.9 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS05120 -4.2 -7.5 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS20350 -4.2 -7.3 amidophosphoribosyltransferase compare
BWI76_RS00845 -4.0 -6.8 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS24285 -4.0 -8.2 cystathionine beta-lyase compare
BWI76_RS07065 -3.8 -8.1 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS20435 -3.8 -2.2 chorismate synthase compare
BWI76_RS04160 -3.8 -10.1 phosphoserine phosphatase compare
BWI76_RS02995 -3.8 -10.1 aspartate carbamoyltransferase compare
BWI76_RS09910 -3.8 -17.0 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS02735 -3.8 -6.7 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS27860 -3.7 -7.5 D-serine dehydratase conserved
BWI76_RS26455 -3.6 -4.1 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS23365 -3.6 -9.3 LysR family transcriptional regulator compare
BWI76_RS04705 -3.5 -7.2 DNA-binding transcriptional regulator FruR compare
BWI76_RS00400 -3.5 -2.3 glutamine synthetase compare
BWI76_RS01610 -3.5 -6.3 phosphoribosylamine--glycine ligase compare
BWI76_RS05015 -3.5 -4.3 transcriptional regulator compare
BWI76_RS09660 -3.4 -3.2 DNA translocase FtsK compare
BWI76_RS23920 -3.3 -6.6 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS22690 -3.3 -4.6 adenylyl-sulfate kinase compare
BWI76_RS01200 -3.3 -3.1 diaminopimelate epimerase compare
BWI76_RS01185 -3.3 -2.2 adenylate cyclase compare
BWI76_RS00980 -3.2 -8.1 PLP-dependent threonine dehydratase compare
BWI76_RS00835 -3.2 -11.1 phosphoenolpyruvate carboxylase compare
BWI76_RS22760 -3.2 -6.8 sulfite reductase subunit beta compare
BWI76_RS27390 -3.2 -5.3 ribonuclease PH compare
BWI76_RS23230 -3.2 -3.1 exodeoxyribonuclease V subunit beta compare
BWI76_RS07070 -3.2 -7.3 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS23240 -3.1 -4.2 exonuclease V subunit gamma compare
BWI76_RS15825 -3.1 -4.1 hypothetical protein compare
BWI76_RS25645 -3.1 -8.6 shikimate dehydrogenase compare
BWI76_RS22765 -3.0 -10.7 sulfite reductase subunit alpha compare
BWI76_RS00985 -3.0 -8.2 transcriptional regulator IlvY compare
BWI76_RS00960 -2.8 -6.1 acetolactate synthase 2 catalytic subunit compare
BWI76_RS05200 -2.7 -4.0 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS22805 -2.7 -9.8 GTP diphosphokinase compare
BWI76_RS11845 -2.7 -1.3 tryptophan synthase subunit beta compare
BWI76_RS21070 -2.4 -2.7 outer membrane protein assembly factor BamB compare
BWI76_RS08405 -2.2 -2.6 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS20970 -2.2 -2.2 phosphoribosylglycinamide formyltransferase compare
BWI76_RS08395 -2.2 -2.8 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS26000 -2.2 -9.1 aspartate aminotransferase family protein compare
BWI76_RS00965 -2.2 -1.8 acetolactate synthase 2 small subunit compare
BWI76_RS06475 -2.0 -1.3 protoheme IX farnesyltransferase compare
BWI76_RS27430 -2.0 -1.9 (p)ppGpp synthetase compare
BWI76_RS02410 -2.0 -2.3 EF-P beta-lysylation protein EpmB compare
BWI76_RS08210 -1.9 -2.4 N-acetylglucosamine-6-phosphate deacetylase compare
BWI76_RS26055 -1.9 -8.1 siroheme synthase compare
BWI76_RS25960 -1.8 -5.0 NUDIX hydrolase compare
BWI76_RS01350 -1.8 -1.2 NAD(P)H-flavin reductase compare
BWI76_RS08425 -1.8 -4.9 succinyl-CoA ligase subunit beta compare
BWI76_RS27850 -1.7 -4.9 DNA-binding transcriptional regulator DsdC compare
BWI76_RS20440 -1.7 -1.9 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS02985 -1.6 -5.2 reactive intermediate/imine deaminase compare
BWI76_RS05450 -1.6 -1.8 ribonuclease HI compare
BWI76_RS21140 -1.6 -3.4 molecular chaperone HscA compare
BWI76_RS08430 -1.5 -3.2 succinate--CoA ligase subunit alpha compare
BWI76_RS20640 -1.5 -4.1 cysteine synthase A compare
BWI76_RS23480 -1.5 -8.3 EAL domain-containing protein compare
BWI76_RS01195 -1.4 -1.9 membrane protein compare
BWI76_RS10575 -1.4 -1.9 polar amino acid ABC transporter permease compare
BWI76_RS00390 -1.4 -2.9 two-component system sensor histidine kinase NtrB compare
BWI76_RS11520 -1.4 -1.2 hypothetical protein compare
BWI76_RS01325 -1.4 -2.8 twin-arginine translocase subunit TatB compare
BWI76_RS26075 -1.4 -2.4 DNA adenine methylase compare
BWI76_RS27440 -1.4 -4.3 DNA helicase RecG compare
BWI76_RS06185 -1.3 -5.6 shikimate kinase II compare
BWI76_RS20650 -1.3 -2.5 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS19010 -1.3 -3.2 polysaccharide pyruvyl transferase yvff compare
BWI76_RS06490 -1.3 -5.5 cytochrome ubiquinol oxidase subunit I compare
BWI76_RS25280 -1.3 -2.0 RNase adaptor protein RapZ compare
BWI76_RS04530 -1.3 -2.4 peptidylprolyl isomerase SurA compare
BWI76_RS15830 -1.3 -3.0 hypothetical protein compare
BWI76_RS23580 -1.3 -2.7 hypothetical protein compare
BWI76_RS21480 -1.3 -3.2 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS16275 -1.2 -2.4 fumarate hydratase FumA compare
BWI76_RS25355 -1.2 -6.0 cell division protein ZapE compare
BWI76_RS09195 -1.2 -2.1 N-acetyltransferase compare
BWI76_RS09255 -1.2 -2.2 hypothetical protein compare
BWI76_RS14835 -1.2 -1.2 hypothetical protein compare
BWI76_RS00025 -1.2 -1.0 hypothetical protein compare
BWI76_RS25600 -1.2 -1.1 tRNA-Thr compare
BWI76_RS19670 -1.2 -2.8 S-formylglutathione hydrolase compare
BWI76_RS21580 -1.2 -1.6 SsrA-binding protein compare
BWI76_RS09625 -1.1 -1.6 hypothetical protein compare
BWI76_RS07605 -1.1 -3.1 N-acetyltransferase GCN5 compare
BWI76_RS15850 -1.1 -1.6 DUF1317 domain-containing protein compare
BWI76_RS11155 -1.1 -2.4 penicillin-binding protein activator LpoB compare
BWI76_RS07645 -1.1 -1.8 short-chain dehydrogenase/reductase compare
BWI76_RS04715 -1.1 -1.8 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS15835 -1.1 -0.8 hypothetical protein compare
BWI76_RS15840 -1.1 -2.8 prophage protein compare
BWI76_RS26395 -1.1 -4.3 cell division protein FtsE compare
BWI76_RS25335 -1.1 -1.6 stringent starvation protein A compare
BWI76_RS16335 -1.1 -1.7 division septum protein Blr compare
BWI76_RS01115 -1.1 -1.8 dTDP-4-amino-4,6-dideoxygalactose transaminase compare
BWI76_RS15975 -1.1 -1.1 hypothetical protein compare
BWI76_RS15810 -1.1 -3.9 hypothetical protein compare
BWI76_RS15955 -1.0 -4.9 transcriptional regulator compare
BWI76_RS06485 -1.0 -2.2 cytochrome o ubiquinol oxidase subunit III compare
BWI76_RS26980 -1.0 -1.5 cold-shock protein compare
BWI76_RS23830 -1.0 -3.8 hypothetical protein compare
BWI76_RS16955 -1.0 -1.5 hypothetical protein compare
BWI76_RS26570 -1.0 -2.2 anion permease compare
BWI76_RS12145 -1.0 -1.4 hypothetical protein compare
BWI76_RS00355 -1.0 -2.3 DNA polymerase I compare
BWI76_RS12185 -1.0 -1.9 hypothetical protein compare
BWI76_RS22695 -1.0 -3.0 sulfate adenylyltransferase compare
BWI76_RS06495 -1.0 -5.4 cytochrome ubiquinol oxidase subunit II compare
BWI76_RS27435 -1.0 -4.1 tRNA (guanosine(18)-2'-O)-methyltransferase TrmH compare
BWI76_RS06765 -1.0 -3.0 transcriptional regulator compare
BWI76_RS23265 -1.0 -2.5 hypothetical protein compare
BWI76_RS11820 -1.0 -1.3 short-chain dehydrogenase/reductase SDR compare
BWI76_RS14075 -1.0 -1.0 TetR family transcriptional regulator compare
BWI76_RS20340 -0.9 -2.4 histidine ABC transporter substrate-binding protein HisJ compare
BWI76_RS23895 -0.9 -1.5 Xaa-Pro aminopeptidase compare
BWI76_RS10035 -0.9 -1.7 hypothetical protein compare
BWI76_RS15630 -0.9 -3.0 hypothetical protein compare
BWI76_RS00140 -0.9 -1.0 phosphate transport system regulator PhoU compare
BWI76_RS00180 -0.9 -1.0 F0F1 ATP synthase subunit epsilon compare
BWI76_RS26685 -0.9 -4.0 glutathione-disulfide reductase compare
BWI76_RS25065 -0.9 -2.5 polyribonucleotide nucleotidyltransferase compare
BWI76_RS20165 -0.9 -3.8 NADH-quinone oxidoreductase subunit G compare
BWI76_RS11435 -0.9 -1.3 hypothetical protein compare
BWI76_RS21450 -0.9 -1.8 23S rRNA pseudouridine(1911/1915/1917) synthase compare
BWI76_RS01630 -0.9 -1.0 16S ribosomal RNA compare
BWI76_RS01170 -0.9 -3.4 uroporphyrinogen-III C-methyltransferase compare
BWI76_RS19730 -0.9 -2.0 1-phosphofructokinase compare
BWI76_RS08525 -0.9 -1.8 colicin transporter compare
BWI76_RS09640 -0.9 -2.3 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD compare
BWI76_RS15715 -0.9 -2.2 putative ninG protein compare
BWI76_RS04570 -0.9 -4.1 RNA polymerase-associated protein RapA compare
BWI76_RS24070 -0.9 -2.3 16S rRNA (uracil(1498)-N(3))-methyltransferase compare
BWI76_RS27855 -0.9 -3.0 D-serine transporter DsdX compare
BWI76_RS01100 -0.8 -2.7 dTDP-glucose 4,6-dehydratase compare
BWI76_RS12755 -0.8 -2.5 hypothetical protein compare
BWI76_RS13400 -0.8 -1.7 GntR family transcriptional regulator compare
BWI76_RS20190 -0.8 -4.0 NADH-quinone oxidoreductase subunit A compare
BWI76_RS17370 -0.8 -1.4 nitrate transporter NasD compare
BWI76_RS20170 -0.8 -2.3 NADH-quinone oxidoreductase subunit F compare
BWI76_RS10330 -0.8 -2.9 TetR family transcriptional regulator compare
BWI76_RS25320 -0.8 -5.3 glutamate synthase compare
BWI76_RS23490 -0.8 -4.4 fimbrial protein compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source D-Serine in Klebsiella michiganensis M5al

For carbon source D-Serine across organisms