Experiment set5IT017 for Klebsiella michiganensis M5al

Compare to:

D-Serine carbon source

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS01680 +1.8 6.9 transcriptional regulator IclR compare
BWI76_RS01585 +1.3 5.7 transcriptional regulator compare
BWI76_RS12485 +1.2 4.0 TyrR family transcriptional regulator compare
BWI76_RS15150 +1.2 5.4 outer membrane efflux protein compare
BWI76_RS03045 +1.2 2.0 hypothetical protein compare
BWI76_RS20230 +1.2 1.2 hypothetical protein compare
BWI76_RS15015 +1.0 1.8 DUF2132 domain-containing protein compare
BWI76_RS02180 +1.0 1.4 hypothetical protein compare
BWI76_RS23690 +1.0 2.5 putative glyoxalase/bleomycin resistance protein/dioxygenase compare
BWI76_RS16000 +0.9 1.6 multidrug transporter subunit MdtI compare
BWI76_RS24575 +0.9 1.2 hypothetical protein compare
BWI76_RS08380 +0.9 1.4 endonuclease VIII compare
BWI76_RS07740 +0.9 2.1 Fe2+-enterobactin ABC transporter substrate-binding protein compare
BWI76_RS16355 +0.9 1.4 electron transport complex subunit A compare
BWI76_RS09335 +0.8 1.3 baseplate assembly protein W compare
BWI76_RS05070 +0.8 1.8 type II secretion system protein GspH compare
BWI76_RS06540 +0.8 2.8 DNA-binding protein HU-beta compare
BWI76_RS24270 +0.8 2.0 membrane protein compare
BWI76_RS04985 +0.8 3.6 aspartate 1-decarboxylase compare
BWI76_RS26285 +0.8 2.5 glycerophosphodiester phosphodiesterase compare
BWI76_RS22935 +0.8 1.1 L-fucose mutarotase compare
BWI76_RS11700 +0.8 1.2 hypothetical protein compare
BWI76_RS11010 +0.8 1.8 30S ribosomal protein S5 alanine N-acetyltransferase compare
BWI76_RS05785 +0.8 2.8 CI repressor compare
BWI76_RS15235 +0.8 2.9 hypothetical protein compare
BWI76_RS05570 +0.8 1.3 hypothetical protein compare
BWI76_RS00440 +0.7 1.5 CopG family transcriptional regulator compare
BWI76_RS15030 +0.7 2.3 ABC transporter compare
BWI76_RS05235 +0.7 1.2 hypothetical protein compare
BWI76_RS13195 +0.7 2.0 glutamate dehydrogenase compare
BWI76_RS09440 +0.7 1.7 hypothetical protein compare
BWI76_RS06805 +0.7 1.3 primosomal replication protein N'' compare
BWI76_RS02870 +0.7 2.0 hypothetical protein compare
BWI76_RS26365 +0.7 3.0 branched chain amino acid ABC transporter substrate-binding protein compare
BWI76_RS16015 +0.7 2.2 pheromone autoinducer 2 transporter compare
BWI76_RS01995 +0.7 0.9 AraC family transcriptional regulator compare
BWI76_RS07260 +0.7 1.8 branched chain amino acid ABC transporter substrate-binding protein compare
BWI76_RS18780 +0.7 1.3 D-alanyl-D-alanine carboxypeptidase compare
BWI76_RS17185 +0.7 3.0 fructosamine kinase family protein compare
BWI76_RS15795 +0.7 2.6 bacteriophage CII family protein compare
BWI76_RS23745 +0.7 3.0 arsenate reductase compare
BWI76_RS20560 +0.6 1.6 hypothetical protein compare
BWI76_RS27455 +0.6 1.2 DUF805 domain-containing protein compare
BWI76_RS17390 +0.6 1.3 DsrE family protein compare
BWI76_RS27600 +0.6 1.6 tRNA-Sec compare
BWI76_RS19325 +0.6 0.8 mandelate racemase compare
BWI76_RS19700 +0.6 1.0 deoxyribonuclease IV compare
BWI76_RS18410 +0.6 1.4 drug/metabolite exporter YedA compare
BWI76_RS19835 +0.6 2.3 nucleoid-associated protein YejK compare
BWI76_RS08220 +0.6 2.3 PTS N-acetyl glucosamine transporter subunit IIABC compare
BWI76_RS08735 +0.6 2.4 Urocanate hydratase (EC 4.2.1.49) (from data) compare
BWI76_RS15215 +0.6 0.8 N-acetyltransferase compare
BWI76_RS11285 +0.6 1.3 transcriptional regulator compare
BWI76_RS16645 +0.6 1.8 DeoR family transcriptional regulator compare
BWI76_RS07895 +0.6 1.5 sugar ABC transporter ATPase compare
BWI76_RS02695 +0.6 2.2 peptidyl-prolyl cis-trans isomerase compare
BWI76_RS25915 +0.6 1.2 protein SlyX compare
BWI76_RS19865 +0.6 1.3 ecotin compare
BWI76_RS05160 +0.6 3.4 hypothetical protein compare
BWI76_RS19575 +0.6 1.8 maleylacetoacetate isomerase compare
BWI76_RS00720 +0.6 1.8 DNA-binding response regulator compare
BWI76_RS04565 +0.6 1.8 bifunctional tRNA pseudouridine(32) synthase/ribosomal large subunit pseudouridine synthase RluA compare
BWI76_RS12470 +0.6 1.1 thiosulfate sulfurtransferase PspE compare
BWI76_RS26020 +0.6 1.8 peptidylprolyl isomerase A compare
BWI76_RS22640 +0.6 1.1 hypothetical protein compare
BWI76_RS26350 +0.6 2.5 branched chain amino acid ABC transporter substrate-binding protein compare
BWI76_RS20720 +0.6 0.5 hypothetical protein compare
BWI76_RS06130 +0.6 1.9 extensin family protein compare
BWI76_RS01010 +0.6 2.5 uridine phosphorylase compare
BWI76_RS12870 +0.6 1.1 putative phytanoyl-CoA dioxygenase compare
BWI76_RS21910 +0.6 1.6 glyoxylate/hydroxypyruvate reductase A compare
BWI76_RS09080 +0.6 1.9 molybdopterin-synthase adenylyltransferase MoeB compare
BWI76_RS17770 +0.6 1.5 isomerase/hydrolase compare
BWI76_RS15035 +0.6 0.7 metal ABC transporter permease compare
BWI76_RS08230 +0.5 1.1 hypothetical protein compare
BWI76_RS25435 +0.5 2.8 membrane protein compare
BWI76_RS18360 +0.5 1.3 aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase family protein compare
BWI76_RS15960 +0.5 1.2 LysR family transcriptional regulator compare
BWI76_RS11970 +0.5 1.7 stress response translation initiation inhibitor YciH compare
BWI76_RS26405 +0.5 1.1 16S rRNA (guanine(966)-N(2))-methyltransferase compare
BWI76_RS13890 +0.5 0.9 LysR family transcriptional regulator compare
BWI76_RS16195 +0.5 1.2 hypothetical protein compare
BWI76_RS08765 +0.5 1.1 8-amino-7-oxononanoate synthase compare
BWI76_RS24150 +0.5 2.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB compare
BWI76_RS14680 +0.5 1.6 SefF compare
BWI76_RS26575 +0.5 2.2 universal stress protein B compare
BWI76_RS14980 +0.5 1.3 hypothetical protein compare
BWI76_RS24180 +0.5 0.8 hypothetical protein compare
BWI76_RS12585 +0.5 1.7 transcriptional regulator compare
BWI76_RS18650 +0.5 2.0 fimbrial protein compare
BWI76_RS10435 +0.5 1.3 suppressor for copper-sensitivity C compare
BWI76_RS03800 +0.5 1.6 hypothetical protein compare
BWI76_RS19535 +0.5 1.6 putative integral membrane protein compare
BWI76_RS14935 +0.5 0.9 NIPSNAP family containing protein compare
BWI76_RS24925 +0.5 1.5 DnaA initiator-associating protein DiaA compare
BWI76_RS16325 +0.5 1.6 adenosine deaminase compare
BWI76_RS17765 +0.5 1.6 hypothetical protein compare
BWI76_RS11125 +0.5 0.9 metal-dependent hydrolase compare
BWI76_RS07985 +0.5 0.7 fluoride ion transporter CrcB compare
BWI76_RS11675 +0.5 0.9 arginine N-succinyltransferase compare
BWI76_RS20565 +0.5 0.7 hypothetical protein compare
BWI76_RS20885 +0.5 2.3 tRNA(Met) cytidine acetyltransferase TmcA compare
BWI76_RS20945 +0.5 2.0 uracil phosphoribosyltransferase compare
BWI76_RS02225 +0.5 1.2 phosphonate C-P lyase system protein PhnG compare
BWI76_RS06405 +0.5 1.8 2-dehydropantoate 2-reductase compare
BWI76_RS23535 +0.5 1.9 hypothetical protein compare
BWI76_RS15985 +0.5 2.5 LysR family transcriptional regulator compare
BWI76_RS25510 +0.5 2.0 oxidoreductase compare
BWI76_RS24385 +0.5 2.9 phosphodiesterase compare
BWI76_RS13820 +0.5 1.1 hypothetical protein compare
BWI76_RS24010 +0.5 1.6 hypothetical protein compare
BWI76_RS23125 +0.5 0.9 propanediol dehydratase small subunit compare
BWI76_RS16810 +0.5 1.9 RpiR family transcriptional regulator compare
BWI76_RS20085 +0.5 2.3 GNAT family N-acetyltransferase compare
BWI76_RS15285 +0.5 1.4 stress protection protein MarC compare
BWI76_RS11890 +0.5 1.5 glycosyl hydrolase compare
BWI76_RS15925 +0.5 1.4 dimethyl sulfoxide reductase subunit A compare
BWI76_RS24245 +0.5 2.1 bifunctional glutathionylspermidine amidase/glutathionylspermidine synthase compare
BWI76_RS17970 +0.5 1.4 zinc metalloprotease HtpX compare
BWI76_RS03005 +0.5 1.9 hypothetical protein compare
BWI76_RS14510 +0.5 1.5 MFS transporter compare
BWI76_RS24810 +0.5 1.0 hypothetical protein compare
BWI76_RS25545 +0.5 1.0 hypothetical protein compare
BWI76_RS16400 +0.5 1.5 pyridoxal kinase compare
BWI76_RS16660 +0.5 1.1 SfnB family sulfur acquisition oxidoreductase compare
BWI76_RS08580 +0.5 1.0 quinolinate synthetase compare
BWI76_RS12780 +0.5 1.4 hypothetical protein compare
BWI76_RS13970 +0.5 0.9 ABC transporter compare
BWI76_RS05555 +0.5 1.6 Crl family RNA polymerase assembly factor compare
BWI76_RS19195 +0.5 1.6 nickel ABC transporter permease compare
BWI76_RS01895 +0.5 0.9 cupin compare
BWI76_RS12070 +0.5 0.6 hypothetical protein compare
BWI76_RS23320 +0.5 0.8 hypothetical protein compare
BWI76_RS04955 +0.5 1.0 hypoxanthine phosphoribosyltransferase compare
BWI76_RS00095 +0.4 1.6 DNA-binding transcriptional regulator compare
BWI76_RS09680 +0.4 1.3 dimethyl sulfoxide reductase subunit A compare
BWI76_RS24290 +0.4 1.0 membrane protein compare
BWI76_RS14930 +0.4 1.4 hypothetical protein compare
BWI76_RS22815 +0.4 3.0 hybrid sensor histidine kinase/response regulator compare
BWI76_RS07755 +0.4 1.2 isochorismatase compare
BWI76_RS22325 +0.4 2.4 hydrogenase 3 membrane subunit compare
BWI76_RS25630 +0.4 1.3 hypothetical protein compare
BWI76_RS15045 +0.4 1.5 LysR family transcriptional regulator compare
BWI76_RS16120 +0.4 1.1 4-carboxymuconolactone decarboxylase compare
BWI76_RS21410 +0.4 1.2 lipoprotein compare
BWI76_RS06665 +0.4 0.6 membrane protein compare
BWI76_RS08450 +0.4 1.6 fumarate hydratase compare
BWI76_RS11390 +0.4 1.9 iron dicitrate transport regulator FecR compare
BWI76_RS02875 +0.4 2.3 membrane protein compare
BWI76_RS26505 +0.4 0.9 nickel ABC transporter permease subunit NikB compare
BWI76_RS08750 +0.4 0.8 kinase inhibitor compare
BWI76_RS04895 +0.4 1.2 hypothetical protein compare
BWI76_RS24785 +0.4 2.1 DUF805 domain-containing protein compare
BWI76_RS07450 +0.4 1.2 transcriptional regulator compare
BWI76_RS16675 +0.4 0.6 ABC transporter compare
BWI76_RS03105 +0.4 0.6 myo-inosose-2 dehydratase compare
BWI76_RS07795 +0.4 2.1 oxidoreductase compare
BWI76_RS06075 +0.4 1.4 taurine transporter subunit compare
BWI76_RS16210 +0.4 1.0 hypothetical protein compare
BWI76_RS23285 +0.4 1.5 hypothetical protein compare
BWI76_RS10975 +0.4 1.4 N-methyltryptophan oxidase compare
BWI76_RS07475 +0.4 0.5 DNA-binding transcriptional regulator RamA compare
BWI76_RS08315 +0.4 1.0 K+-transporting ATPase subunit B compare
BWI76_RS22940 +0.4 1.6 DNA-binding transcriptional activator FucR compare
BWI76_RS26300 +0.4 1.5 glycerol-3-phosphate transporter permease compare
BWI76_RS13175 +0.4 1.6 NodT family RND efflux system outer membrane lipoprotein compare
BWI76_RS24065 +0.4 1.9 deoxyribonuclease I compare
BWI76_RS17945 +0.4 1.0 hypothetical protein compare
BWI76_RS13135 +0.4 1.0 3-oxoadipyl-CoA thiolase compare
BWI76_RS10755 +0.4 0.8 pyrimidine utilization flavin reductase protein F compare
BWI76_RS21740 +0.4 1.1 transcriptional regulator, LysR family protein compare
BWI76_RS14770 +0.4 0.7 PTS IIA 2 domain protein compare
BWI76_RS00640 +0.4 1.2 L-rhamnose mutarotase compare
BWI76_RS11360 +0.4 0.9 L-asparaginase compare
BWI76_RS22190 +0.4 2.0 hypothetical protein compare
BWI76_RS18610 +0.4 1.1 transcriptional regulator LysR compare
BWI76_RS11705 +0.4 1.4 hypothetical protein compare
BWI76_RS27565 +0.4 1.9 sugar aldolase compare
BWI76_RS25655 +0.4 1.5 DNA topoisomerase type IA zn finger domain-containing protein compare
BWI76_RS18745 +0.4 1.1 adenosylhomocysteinase compare
BWI76_RS06815 +0.4 1.3 adenine phosphoribosyltransferase compare
BWI76_RS06470 +0.4 1.3 hypothetical protein compare
BWI76_RS14480 +0.4 2.0 hypothetical protein compare
BWI76_RS04990 +0.4 2.3 pantoate--beta-alanine ligase compare
BWI76_RS17570 +0.4 1.0 iron-sulfur-binding protein compare
BWI76_RS21660 +0.4 0.8 antirestriction protein compare
BWI76_RS09330 +0.4 0.7 baseplate assembly protein V compare
BWI76_RS20805 +0.4 1.8 phosphate acetyltransferase compare
BWI76_RS20395 +0.4 1.1 flagella biosynthesis regulator compare
BWI76_RS21915 +0.4 1.9 short-chain dehydrogenase/reductase SDR compare
BWI76_RS20360 +0.4 0.5 cell division protein DedD compare
BWI76_RS01245 +0.4 2.5 DNA helicase RecQ compare
BWI76_RS20310 +0.4 1.5 hypothetical protein compare
BWI76_RS13240 +0.4 0.8 hypothetical protein compare
BWI76_RS13420 +0.4 0.8 ABC transporter permease compare
BWI76_RS21490 +0.4 2.5 GGDEF domain-containing protein compare
BWI76_RS16900 +0.4 0.9 4-hydroxy-2-oxovalerate aldolase compare
BWI76_RS20635 +0.4 1.4 sulfate transporter CysZ compare
BWI76_RS19770 +0.4 0.8 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase compare
BWI76_RS15800 +0.4 1.0 transcriptional regulator compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source D-Serine in Klebsiella michiganensis M5al

For carbon source D-Serine across organisms