Experiment set5IT016 for Klebsiella michiganensis M5al

Compare to:

L-Alanine carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS18935 -7.6 -7.4 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS04255 -7.1 -4.9 threonine synthase compare
BWI76_RS09755 -6.8 -6.7 phosphoserine transaminase compare
BWI76_RS04670 -6.6 -9.1 3-isopropylmalate dehydratase large subunit compare
BWI76_RS01615 -6.4 -10.7 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS05835 -6.3 -4.4 gamma-glutamyl-phosphate reductase compare
BWI76_RS18950 -6.3 -4.3 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS00855 -6.3 -8.6 argininosuccinate lyase compare
BWI76_RS05840 -6.3 -6.1 glutamate 5-kinase compare
BWI76_RS04250 -6.3 -8.6 homoserine kinase compare
BWI76_RS00980 -6.1 -10.3 PLP-dependent threonine dehydratase compare
BWI76_RS00990 -6.0 -10.0 ketol-acid reductoisomerase compare
BWI76_RS21475 -6.0 -8.2 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS23360 -5.9 -4.1 diaminopimelate decarboxylase compare
BWI76_RS00850 -5.9 -12.7 acetylglutamate kinase compare
BWI76_RS04245 -5.9 -15.3 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS18925 -5.9 -7.0 histidinol dehydrogenase compare
BWI76_RS04470 -5.7 -11.0 carbamoyl phosphate synthase large subunit compare
BWI76_RS00805 -5.7 -6.7 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS04160 -5.6 -6.3 phosphoserine phosphatase compare
BWI76_RS17735 -5.6 -7.6 D-amino acid dehydrogenase small subunit conserved
BWI76_RS00845 -5.5 -10.6 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS03010 -5.5 -9.7 ornithine carbamoyltransferase compare
BWI76_RS18920 -5.5 -4.1 ATP phosphoribosyltransferase compare
BWI76_RS20895 -5.4 -7.3 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS17065 -5.4 -10.9 phosphoenolpyruvate synthase compare
BWI76_RS20965 -5.3 -6.4 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS23220 -5.3 -8.8 amino-acid N-acetyltransferase compare
BWI76_RS05015 -5.1 -5.0 transcriptional regulator compare
BWI76_RS08385 -5.1 -4.8 citrate (Si)-synthase compare
BWI76_RS18930 -5.0 -6.3 histidinol-phosphate transaminase compare
BWI76_RS04645 -5.0 -5.2 3-dehydroquinase compare
BWI76_RS09645 -5.0 -2.0 thioredoxin-disulfide reductase compare
BWI76_RS00965 -5.0 -2.0 acetolactate synthase 2 small subunit compare
BWI76_RS21265 -5.0 -12.7 phosphoribosylformylglycinamidine synthase compare
BWI76_RS23920 -4.9 -7.5 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS11840 -4.9 -4.0 tryptophan synthase subunit alpha compare
BWI76_RS04465 -4.9 -4.9 carbamoyl-phosphate synthase small subunit compare
BWI76_RS25115 -4.9 -5.4 argininosuccinate synthase compare
BWI76_RS04665 -4.8 -18.3 3-isopropylmalate dehydratase small subunit compare
BWI76_RS04675 -4.8 -5.2 3-isopropylmalate dehydrogenase compare
BWI76_RS01655 -4.8 -9.7 homoserine O-succinyltransferase compare
BWI76_RS11850 -4.7 -9.7 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS10990 -4.7 -4.6 dihydroorotase compare
BWI76_RS02995 -4.7 -9.2 aspartate carbamoyltransferase compare
BWI76_RS18955 -4.6 -4.2 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS18940 -4.5 -6.4 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS11965 -4.5 -3.8 orotidine-5'-phosphate decarboxylase compare
BWI76_RS09760 -4.5 -7.4 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS00785 -4.4 -7.9 cystathionine gamma-synthase compare
BWI76_RS11855 -4.4 -9.4 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS20350 -4.4 -5.5 amidophosphoribosyltransferase compare
BWI76_RS26085 -4.4 -3.8 3-dehydroquinate synthase compare
BWI76_RS01210 -4.4 -3.3 tyrosine recombinase XerC compare
BWI76_RS15825 -4.3 -2.8 hypothetical protein compare
BWI76_RS00975 -4.2 -6.9 dihydroxy-acid dehydratase compare
BWI76_RS00835 -4.2 -16.4 phosphoenolpyruvate carboxylase compare
BWI76_RS20355 -4.1 -3.9 colicin V production protein compare
BWI76_RS01610 -4.1 -4.9 phosphoribosylamine--glycine ligase compare
BWI76_RS04240 -4.0 -2.7 thr operon leader peptide compare
BWI76_RS27385 -4.0 -8.8 orotate phosphoribosyltransferase compare
BWI76_RS04680 -3.9 -10.5 2-isopropylmalate synthase compare
BWI76_RS09910 -3.9 -14.7 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS09660 -3.9 -2.7 DNA translocase FtsK compare
BWI76_RS04685 -3.9 -8.4 putative leucine operon leader peptide compare
BWI76_RS07070 -3.9 -3.9 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS04705 -3.8 -6.5 DNA-binding transcriptional regulator FruR compare
BWI76_RS02530 -3.8 -3.7 tRNA dimethylallyltransferase compare
BWI76_RS20435 -3.8 -2.2 chorismate synthase compare
BWI76_RS22755 -3.7 -7.1 phosphoadenosine phosphosulfate reductase compare
BWI76_RS02815 -3.7 -3.1 fructose-bisphosphatase class I compare
BWI76_RS05200 -3.7 -3.6 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS11860 -3.7 -8.3 anthranilate synthase component I compare
BWI76_RS00400 -3.7 -2.4 glutamine synthetase compare
BWI76_RS11845 -3.6 -3.5 tryptophan synthase subunit beta compare
BWI76_RS23240 -3.5 -4.2 exonuclease V subunit gamma compare
BWI76_RS23365 -3.5 -9.3 LysR family transcriptional regulator compare
BWI76_RS21465 -3.3 -3.2 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS23230 -3.2 -3.1 exodeoxyribonuclease V subunit beta compare
BWI76_RS07065 -3.2 -8.2 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS09635 -3.1 -4.3 amino acid ABC transporter ATP-binding protein compare
BWI76_RS09640 -3.1 -5.1 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD compare
BWI76_RS02735 -3.0 -6.6 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS20270 -2.9 -9.5 hypothetical protein compare
BWI76_RS27390 -2.9 -4.5 ribonuclease PH compare
BWI76_RS08535 -2.8 -2.9 translocation protein TolB compare
BWI76_RS08395 -2.7 -2.9 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS08520 -2.6 -3.4 colicin transporter TolQ compare
BWI76_RS23885 -2.5 -2.0 2-octaprenylphenol hydroxylase compare
BWI76_RS20650 -2.5 -2.9 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS17720 -2.4 -2.2 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS22765 -2.4 -11.9 sulfite reductase subunit alpha compare
BWI76_RS24900 -2.4 -2.3 DeoR family transcriptional regulator compare
BWI76_RS06530 -2.4 -5.5 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS06525 -2.3 -5.9 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS00180 -2.3 -2.9 F0F1 ATP synthase subunit epsilon compare
BWI76_RS04530 -2.2 -2.3 peptidylprolyl isomerase SurA compare
BWI76_RS00140 -2.2 -1.7 phosphate transport system regulator PhoU compare
BWI76_RS24285 -2.1 -7.0 cystathionine beta-lyase compare
BWI76_RS02985 -2.1 -6.1 reactive intermediate/imine deaminase compare
BWI76_RS26175 -2.1 -5.2 DeoR/GlpR family transcriptional regulator compare
BWI76_RS06730 -2.0 -3.5 lac repressor compare
BWI76_RS20995 -2.0 -6.1 RNA degradosome polyphosphate kinase compare
BWI76_RS01185 -2.0 -2.9 adenylate cyclase compare
BWI76_RS25425 -2.0 -2.4 arginine repressor compare
BWI76_RS01350 -1.9 -1.3 NAD(P)H-flavin reductase compare
BWI76_RS15760 -1.9 -2.4 hypothetical protein compare
BWI76_RS25600 -1.9 -1.5 tRNA-Thr compare
BWI76_RS26460 -1.9 -4.9 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS26455 -1.9 -4.4 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS25960 -1.9 -5.5 NUDIX hydrolase compare
BWI76_RS03080 -1.9 -4.3 (Fe-S)-cluster assembly protein compare
BWI76_RS22760 -1.8 -5.3 sulfite reductase subunit beta compare
BWI76_RS00345 -1.7 -3.1 protein disulfide oxidoreductase DsbA compare
BWI76_RS13435 -1.7 -2.3 hypothetical protein compare
BWI76_RS22420 -1.6 -2.8 LacI family transcriptional regulator compare
BWI76_RS13980 -1.6 -1.4 hypothetical protein compare
BWI76_RS25420 -1.5 -7.1 malate dehydrogenase compare
BWI76_RS04305 -1.5 -0.8 molecular chaperone DnaJ compare
BWI76_RS08525 -1.5 -2.5 colicin transporter compare
BWI76_RS07465 -1.5 -3.2 TetR family transcriptional regulator compare
BWI76_RS01800 -1.5 -4.0 glucose-6-phosphate isomerase compare
BWI76_RS05450 -1.5 -1.3 ribonuclease HI compare
BWI76_RS25065 -1.5 -3.9 polyribonucleotide nucleotidyltransferase compare
BWI76_RS12185 -1.5 -2.5 hypothetical protein compare
BWI76_RS23480 -1.5 -8.5 EAL domain-containing protein compare
BWI76_RS11610 -1.4 -1.8 glutamate dehydrogenase compare
BWI76_RS20440 -1.4 -2.2 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS22240 -1.4 -4.2 transcriptional regulator compare
BWI76_RS22805 -1.4 -5.5 GTP diphosphokinase compare
BWI76_RS27475 -1.4 -8.0 regulatory protein GntR family protein compare
BWI76_RS00875 -1.3 -5.7 DNA-binding transcriptional regulator FabR compare
BWI76_RS05260 -1.3 -1.8 chaperone compare
BWI76_RS03225 -1.3 -6.1 transcriptional regulator compare
BWI76_RS06185 -1.3 -5.9 shikimate kinase II compare
BWI76_RS21100 -1.3 -3.4 nucleoside-diphosphate kinase compare
BWI76_RS27440 -1.3 -4.3 DNA helicase RecG compare
BWI76_RS15810 -1.3 -3.5 hypothetical protein compare
BWI76_RS20380 -1.3 -1.3 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS08405 -1.3 -1.9 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS09190 -1.3 -3.4 hypothetical protein compare
BWI76_RS06535 -1.3 -4.0 endopeptidase La compare
BWI76_RS02990 -1.3 -3.8 aspartate carbamoyltransferase regulatory subunit compare
BWI76_RS17155 -1.3 -1.9 hypothetical protein compare
BWI76_RS08730 -1.2 -3.1 histidine utilization repressor compare
BWI76_RS19010 -1.2 -3.2 polysaccharide pyruvyl transferase yvff compare
BWI76_RS18165 -1.2 -1.5 NUDIX pyrophosphatase compare
BWI76_RS25975 -1.2 -5.1 phosphoribulokinase compare
BWI76_RS15840 -1.2 -2.3 prophage protein compare
BWI76_RS16230 -1.2 -2.9 dihydromonapterin reductase compare
BWI76_RS22690 -1.2 -3.7 adenylyl-sulfate kinase compare
BWI76_RS25160 -1.2 -1.8 transcription elongation factor GreA compare
BWI76_RS21675 -1.2 -1.4 hypothetical protein compare
BWI76_RS26570 -1.2 -3.0 anion permease compare
BWI76_RS15650 -1.2 -4.6 gp5 compare
BWI76_RS05120 -1.2 -5.0 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS26075 -1.2 -2.6 DNA adenine methylase compare
BWI76_RS19035 -1.1 -5.9 dTDP-rhamnosyl transferase compare
BWI76_RS15955 -1.1 -7.4 transcriptional regulator compare
BWI76_RS12450 -1.1 -1.5 phage shock protein PspA compare
BWI76_RS21165 -1.1 -1.8 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS11300 -1.1 -1.3 cupin compare
BWI76_RS04510 -1.1 -1.9 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS01095 -1.1 -2.6 UDP-N-acetyl-D-mannosamine dehydrogenase compare
BWI76_RS02725 -1.1 -1.0 HxlR family transcriptional regulator compare
BWI76_RS27075 -1.1 -4.0 IclR family transcriptional regulator compare
BWI76_RS02970 -1.1 -3.8 trehalose operon repressor compare
BWI76_RS09655 -1.1 -3.1 leucine-responsive regulatory protein compare
BWI76_RS21310 -1.1 -1.1 DNA repair protein RecO compare
BWI76_RS04715 -1.1 -1.6 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS09650 -1.0 -4.5 hypothetical protein compare
BWI76_RS24925 -1.0 -1.2 DnaA initiator-associating protein DiaA compare
BWI76_RS00065 -1.0 -4.4 MurR/RpiR family transcriptional regulator compare
BWI76_RS18605 -1.0 -1.4 oxidoreductase molybdopterin-binding protein compare
BWI76_RS00985 -1.0 -3.7 transcriptional regulator IlvY compare
BWI76_RS10330 -1.0 -2.1 TetR family transcriptional regulator compare
BWI76_RS03415 -1.0 -3.4 LacI family transcriptional regulator compare
BWI76_RS11255 -1.0 -1.2 putrescine/spermidine ABC transporter ATP-binding protein compare
BWI76_RS15830 -1.0 -1.7 hypothetical protein compare
BWI76_RS00240 -1.0 -2.1 FMN-binding protein MioC compare
BWI76_RS08425 -1.0 -3.7 succinyl-CoA ligase subunit beta compare
BWI76_RS06735 -0.9 -1.7 50S ribosomal protein L31 compare
BWI76_RS11430 -0.9 -0.9 lipoprotein compare
BWI76_RS27430 -0.9 -1.2 (p)ppGpp synthetase compare
BWI76_RS23265 -0.9 -2.7 hypothetical protein compare
BWI76_RS16275 -0.9 -1.7 fumarate hydratase FumA compare
BWI76_RS14075 -0.9 -1.4 TetR family transcriptional regulator compare
BWI76_RS12495 -0.9 -1.4 2-Cys peroxiredoxin compare
BWI76_RS24080 -0.9 -1.1 DUF179 domain-containing protein compare
BWI76_RS00430 -0.9 -2.4 GNAT family N-acetyltransferase compare
BWI76_RS08205 -0.9 -3.4 DNA-binding transcriptional dual regulator NagC compare
BWI76_RS10770 -0.9 -1.1 pyrimidine utilization protein C compare
BWI76_RS18195 -0.9 -3.2 tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB compare
BWI76_RS05885 -0.9 -2.5 anion permease compare
BWI76_RS15060 -0.9 -1.8 MarR family transcriptional regulator compare
BWI76_RS27875 -0.9 -0.6 membrane protein compare
BWI76_RS01200 -0.9 -1.5 diaminopimelate epimerase compare
BWI76_RS01220 -0.9 -3.7 DNA-dependent helicase II compare
BWI76_RS13110 -0.9 -2.3 phenylacetic acid degradation protein compare
BWI76_RS02610 -0.9 -3.3 transcriptional regulator compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source L-Alanine in Klebsiella michiganensis M5al

For carbon source L-Alanine across organisms