Experiment set5IT016 for Klebsiella michiganensis M5al

Compare to:

L-Alanine carbon source

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS18630 +1.6 9.7 nitrogen assimilation transcriptional regulator compare
BWI76_RS01995 +1.2 1.8 AraC family transcriptional regulator compare
BWI76_RS12420 +1.1 2.0 peptide ABC transporter substrate-binding protein SapA compare
BWI76_RS01190 +1.1 3.6 iron donor protein CyaY compare
BWI76_RS01540 +1.0 2.3 thiamine biosynthesis protein ThiS compare
BWI76_RS09870 +1.0 5.4 aromatic amino acid aminotransferase compare
BWI76_RS25285 +1.0 1.4 HPr family phosphocarrier protein compare
BWI76_RS24575 +1.0 1.3 hypothetical protein compare
BWI76_RS04955 +1.0 2.6 hypoxanthine phosphoribosyltransferase compare
BWI76_RS19770 +1.0 2.0 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase compare
BWI76_RS12860 +0.9 1.5 hypothetical protein compare
BWI76_RS15015 +0.9 1.5 DUF2132 domain-containing protein compare
BWI76_RS14770 +0.9 1.6 PTS IIA 2 domain protein compare
BWI76_RS16015 +0.9 3.6 pheromone autoinducer 2 transporter compare
BWI76_RS12585 +0.8 3.7 transcriptional regulator compare
BWI76_RS00720 +0.8 2.3 DNA-binding response regulator compare
BWI76_RS01585 +0.8 4.1 transcriptional regulator compare
BWI76_RS11775 +0.8 2.1 2-deoxy-D-gluconate 3-dehydrogenase compare
BWI76_RS23255 +0.8 2.6 prepilin-type cleavage/methylation domain-containing protein compare
BWI76_RS13970 +0.8 1.7 ABC transporter compare
BWI76_RS25300 +0.8 2.4 hybrid sensor histidine kinase/response regulator compare
BWI76_RS09690 +0.8 2.6 dimethyl sulfoxide reductase compare
BWI76_RS14980 +0.8 1.6 hypothetical protein compare
BWI76_RS05810 +0.8 1.3 hypothetical protein compare
BWI76_RS15950 +0.8 1.8 dethiobiotin synthase compare
BWI76_RS16485 +0.8 1.5 ribonuclease T compare
BWI76_RS17045 +0.8 1.2 hypothetical protein compare
BWI76_RS09860 +0.8 2.9 hypothetical protein compare
BWI76_RS08765 +0.7 2.5 8-amino-7-oxononanoate synthase compare
BWI76_RS11285 +0.7 1.5 transcriptional regulator compare
BWI76_RS22085 +0.7 2.1 L-valine transporter subunit YgaH compare
BWI76_RS10435 +0.7 2.6 suppressor for copper-sensitivity C compare
BWI76_RS12465 +0.7 1.1 phage shock protein D compare
BWI76_RS16150 +0.7 1.7 IclR family transcriptional regulator compare
BWI76_RS26365 +0.7 3.2 branched chain amino acid ABC transporter substrate-binding protein compare
BWI76_RS16900 +0.7 1.9 4-hydroxy-2-oxovalerate aldolase compare
BWI76_RS01330 +0.7 1.7 twin-arginine translocase subunit TatC compare
BWI76_RS11675 +0.7 1.6 arginine N-succinyltransferase compare
BWI76_RS03665 +0.7 1.4 ABC transporter ATP-binding protein compare
BWI76_RS19850 +0.7 2.5 tRNA-Pro compare
BWI76_RS18300 +0.7 1.6 hypothetical protein compare
BWI76_RS11170 +0.7 1.2 hypothetical protein compare
BWI76_RS07760 +0.7 2.7 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase compare
BWI76_RS03045 +0.7 1.0 hypothetical protein compare
BWI76_RS16655 +0.7 3.4 CatA-like O-acetyltransferase compare
BWI76_RS12870 +0.7 1.6 putative phytanoyl-CoA dioxygenase compare
BWI76_RS03005 +0.7 2.6 hypothetical protein compare
BWI76_RS01940 +0.7 1.8 hypothetical protein compare
BWI76_RS14510 +0.7 2.1 MFS transporter compare
BWI76_RS09155 +0.7 3.2 undecaprenyl-diphosphatase compare
BWI76_RS07705 +0.7 2.8 enterochelin esterase compare
BWI76_RS17570 +0.7 2.0 iron-sulfur-binding protein compare
BWI76_RS18770 +0.7 0.8 DNA gyrase inhibitor compare
BWI76_RS15235 +0.6 2.4 hypothetical protein compare
BWI76_RS06330 +0.6 1.5 DNA-binding transcriptional regulator compare
BWI76_RS20805 +0.6 1.9 phosphate acetyltransferase compare
BWI76_RS23125 +0.6 1.5 propanediol dehydratase small subunit compare
BWI76_RS06880 +0.6 2.3 biopolymer transport protein ExbD/TolR compare
BWI76_RS27745 +0.6 1.7 PTS sugar transporter subunit IIB compare
BWI76_RS02050 +0.6 1.5 CidA/LrgA family protein compare
BWI76_RS13095 +0.6 1.0 phenylacetate-CoA oxygenase subunit PaaB compare
BWI76_RS04560 +0.6 2.4 holo-ACP synthase CitX compare
BWI76_RS25935 +0.6 1.8 glutathione-regulated potassium-efflux system ancillary protein KefG compare
BWI76_RS16400 +0.6 2.0 pyridoxal kinase compare
BWI76_RS23140 +0.6 1.3 carboxysome shell protein compare
BWI76_RS27600 +0.6 1.5 tRNA-Sec compare
BWI76_RS12485 +0.6 1.5 TyrR family transcriptional regulator compare
BWI76_RS14575 +0.6 1.5 TENA/THI-4 family protein compare
BWI76_RS08735 +0.6 2.5 Urocanate hydratase (EC 4.2.1.49) (from data) compare
BWI76_RS21140 +0.6 1.3 molecular chaperone HscA compare
BWI76_RS21375 +0.6 1.1 autonomous glycyl radical cofactor GrcA compare
BWI76_RS08230 +0.6 1.9 hypothetical protein compare
BWI76_RS11435 +0.6 0.9 hypothetical protein compare
BWI76_RS13405 +0.6 3.1 spermidine/putrescine ABC transporter substrate-binding protein compare
BWI76_RS20230 +0.6 0.6 hypothetical protein compare
BWI76_RS20560 +0.6 1.4 hypothetical protein compare
BWI76_RS14780 +0.6 1.2 phosphotriesterase compare
BWI76_RS21325 +0.6 1.2 hypothetical protein compare
BWI76_RS08585 +0.6 1.9 nicotinamide riboside transporter PnuC compare
BWI76_RS21995 +0.6 2.1 transcriptional regulator compare
BWI76_RS04200 +0.6 2.7 phosphoglycerate mutase GpmB compare
BWI76_RS11260 +0.6 1.5 hypothetical protein compare
BWI76_RS00285 +0.6 2.0 D-ribose ABC transporter substrate-binding protein compare
BWI76_RS26750 +0.6 2.5 PfkB domain-containing protein compare
BWI76_RS20375 +0.6 1.0 membrane protein compare
BWI76_RS09515 +0.6 1.7 arginine ABC transporter substrate-binding protein compare
BWI76_RS00715 +0.6 1.9 two-component sensor histidine kinase compare
BWI76_RS04565 +0.6 2.0 bifunctional tRNA pseudouridine(32) synthase/ribosomal large subunit pseudouridine synthase RluA compare
BWI76_RS21565 +0.6 0.8 outer membrane protein assembly factor BamE compare
BWI76_RS21130 +0.6 1.2 Fe-S assembly protein IscX compare
BWI76_RS21910 +0.6 1.0 glyoxylate/hydroxypyruvate reductase A compare
BWI76_RS00740 +0.6 2.3 ribonuclease E activity regulator RraA compare
BWI76_RS14170 +0.6 1.8 hypothetical protein compare
BWI76_RS15150 +0.6 1.9 outer membrane efflux protein compare
BWI76_RS14390 +0.6 0.8 hypothetical protein compare
BWI76_RS02180 +0.6 0.8 hypothetical protein compare
BWI76_RS16935 +0.6 0.8 shikimate dehydrogenase compare
BWI76_RS27455 +0.5 1.3 DUF805 domain-containing protein compare
BWI76_RS16195 +0.5 1.3 hypothetical protein compare
BWI76_RS01815 +0.5 1.8 phosphate-starvation-inducible protein PsiE compare
BWI76_RS21580 +0.5 0.8 SsrA-binding protein compare
BWI76_RS12865 +0.5 2.5 acetylornithine deacetylase compare
BWI76_RS23375 +0.5 2.7 cupin compare
BWI76_RS24630 +0.5 3.0 putrescine aminotransferase compare
BWI76_RS11250 +0.5 1.3 spermidine/putrescine ABC transporter permease PotB compare
BWI76_RS08275 +0.5 0.9 LexA regulated protein compare
BWI76_RS13415 +0.5 1.5 spermidine/putrescine ABC transporter permease compare
BWI76_RS05070 +0.5 1.3 type II secretion system protein GspH compare
BWI76_RS16040 +0.5 1.2 biotin-independent malonate decarboxylase subunit gamma compare
BWI76_RS15290 +0.5 0.9 transcriptional regulator compare
BWI76_RS22640 +0.5 1.3 hypothetical protein compare
BWI76_RS15970 +0.5 1.8 carboxypeptidase M32 compare
BWI76_RS13645 +0.5 1.5 N-hydroxyarylamine O-acetyltransferase compare
BWI76_RS11490 +0.5 3.1 MltA-interacting protein MipA compare
BWI76_RS17860 +0.5 1.1 YoaH family protein compare
BWI76_RS23305 +0.5 1.2 NADP(H)-dependent aldo-keto reductase compare
BWI76_RS17500 +0.5 2.5 knotted carbamoyltransferase YgeW compare
BWI76_RS20050 +0.5 0.9 hypothetical protein compare
BWI76_RS13195 +0.5 1.9 glutamate dehydrogenase compare
BWI76_RS23860 +0.5 1.3 protein disulfide oxidoreductase compare
BWI76_RS19975 +0.5 2.3 sn-glycerol-3-phosphate dehydrogenase subunit C compare
BWI76_RS08220 +0.5 2.1 PTS N-acetyl glucosamine transporter subunit IIABC compare
BWI76_RS20925 +0.5 1.8 peptidase M48 compare
BWI76_RS25545 +0.5 0.7 hypothetical protein compare
BWI76_RS18295 +0.5 3.2 tyrosine transporter TyrP compare
BWI76_RS21340 +0.5 0.9 SoxR reducing system protein RseC compare
BWI76_RS08450 +0.5 3.0 fumarate hydratase compare
BWI76_RS02445 +0.5 2.1 fumarate reductase subunit C compare
BWI76_RS17420 +0.5 0.9 hypothetical protein compare
BWI76_RS21660 +0.5 1.0 antirestriction protein compare
BWI76_RS05785 +0.5 1.4 CI repressor compare
BWI76_RS23535 +0.5 1.7 hypothetical protein compare
BWI76_RS10450 +0.5 1.8 tRNA-Tyr compare
BWI76_RS27005 +0.5 1.6 hypothetical protein compare
BWI76_RS11360 +0.5 2.0 L-asparaginase compare
BWI76_RS23035 +0.5 2.6 precorrin-2 C(20)-methyltransferase compare
BWI76_RS13775 +0.5 1.4 putative FMN-dependent luciferase-like monooxygenase compare
BWI76_RS14320 +0.5 1.0 hypothetical protein compare
BWI76_RS03180 +0.5 2.0 phage transcriptional regulator, AlpA compare
BWI76_RS20335 +0.5 1.3 zinc transporter compare
BWI76_RS19835 +0.5 2.0 nucleoid-associated protein YejK compare
BWI76_RS04995 +0.5 1.4 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
BWI76_RS19865 +0.5 1.2 ecotin compare
BWI76_RS09240 +0.5 2.0 phosphoadenosine phosphosulfate reductase compare
BWI76_RS06570 +0.5 1.7 thiamin pyrimidine pyrophosphate hydrolase compare
BWI76_RS18175 +0.5 1.5 hydrolase compare
BWI76_RS23905 +0.5 2.9 Z-ring-associated protein compare
BWI76_RS21185 +0.5 2.6 hypothetical protein compare
BWI76_RS04805 +0.5 1.3 8-oxo-dGTP diphosphatase compare
BWI76_RS16020 +0.5 1.5 malonate decarboxylase subunit alpha compare
BWI76_RS15045 +0.5 2.0 LysR family transcriptional regulator compare
BWI76_RS15265 +0.5 1.9 hypothetical protein compare
BWI76_RS12040 +0.5 0.7 hypothetical protein compare
BWI76_RS03825 +0.5 2.0 4-hydroxyphenylacetate 3-monooxygenase compare
BWI76_RS16915 +0.5 1.2 alpha/beta hydrolase fold protein compare
BWI76_RS15800 +0.4 1.6 transcriptional regulator compare
BWI76_RS18140 +0.4 1.2 zinc ABC transporter permease compare
BWI76_RS15120 +0.4 2.0 hypothetical protein compare
BWI76_RS15275 +0.4 1.3 isomerase compare
BWI76_RS25240 +0.4 1.4 D-arabinose 5-phosphate isomerase compare
BWI76_RS20735 +0.4 1.6 N-acetylmuramoyl-L-alanine amidase compare
BWI76_RS17900 +0.4 1.6 PTS mannose transporter subunit IID compare
BWI76_RS19790 +0.4 1.7 putative binding-protein-dependent transporter compare
BWI76_RS03020 +0.4 1.3 tRNA hydroxylase compare
BWI76_RS06180 +0.4 1.6 hypothetical protein compare
BWI76_RS01260 +0.4 1.8 lysophospholipase L2 compare
BWI76_RS15230 +0.4 1.7 4-hydroxythreonine-4-phosphate dehydrogenase compare
BWI76_RS13060 +0.4 1.3 glutathione S-transferase compare
BWI76_RS25035 +0.4 1.2 malonate transporter subunit MadM compare
BWI76_RS27670 +0.4 1.1 LysR family transcriptional regulator compare
BWI76_RS18550 +0.4 0.8 tRNA-Asn compare
BWI76_RS07260 +0.4 1.1 branched chain amino acid ABC transporter substrate-binding protein compare
BWI76_RS19445 +0.4 2.1 hypothetical protein compare
BWI76_RS00880 +0.4 1.6 membrane protein compare
BWI76_RS27050 +0.4 1.9 hypothetical protein compare
BWI76_RS01580 +0.4 1.2 hypothetical protein compare
BWI76_RS00690 +0.4 1.7 transcriptional activator RhaS compare
BWI76_RS24970 +0.4 2.4 peptidase U32 compare
BWI76_RS19300 +0.4 2.4 ABC transporter ATP-binding protein compare
BWI76_RS09145 +0.4 0.9 serine-type D-Ala-D-Ala carboxypeptidase compare
BWI76_RS13890 +0.4 1.1 LysR family transcriptional regulator compare
BWI76_RS16160 +0.4 1.2 LysR family transcriptional regulator compare
BWI76_RS17185 +0.4 1.6 fructosamine kinase family protein compare
BWI76_RS20885 +0.4 1.4 tRNA(Met) cytidine acetyltransferase TmcA compare
BWI76_RS26485 +0.4 2.2 UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase compare
BWI76_RS24150 +0.4 1.9 tRNA (guanosine(46)-N7)-methyltransferase TrmB compare
BWI76_RS03105 +0.4 0.6 myo-inosose-2 dehydratase compare
BWI76_RS19375 +0.4 1.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase compare
BWI76_RS10400 +0.4 1.4 hypothetical protein compare
BWI76_RS11770 +0.4 1.2 hypothetical protein compare
BWI76_RS26475 +0.4 2.3 bifunctional UDP-glucuronic acid oxidase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase compare
BWI76_RS08095 +0.4 2.5 arginine ABC transporter ATP-binding protein compare
BWI76_RS07775 +0.4 2.1 carbon starvation protein A compare
BWI76_RS11890 +0.4 1.9 glycosyl hydrolase compare
BWI76_RS11640 +0.4 1.3 ABC transporter membrane protein compare
BWI76_RS08655 +0.4 1.0 molybdenum ABC transporter ATP-binding protein compare
BWI76_RS12750 +0.4 1.3 hypothetical protein compare
BWI76_RS13250 +0.4 0.5 cytochrome b561 compare
BWI76_RS20720 +0.4 0.6 hypothetical protein compare
BWI76_RS19615 +0.4 1.7 vancomycin high temperature exclusion protein compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source L-Alanine in Klebsiella michiganensis M5al

For carbon source L-Alanine across organisms