Experiment set5IT015 for Klebsiella michiganensis M5al

Compare to:

L-Glutamine carbon source

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS08730 +6.9 11.6 histidine utilization repressor compare
BWI76_RS05015 +3.0 6.7 transcriptional regulator compare
BWI76_RS25335 +3.0 13.0 stringent starvation protein A compare
BWI76_RS09655 +2.9 10.7 leucine-responsive regulatory protein compare
BWI76_RS09650 +2.4 11.9 hypothetical protein compare
BWI76_RS00295 +1.8 7.8 transcriptional regulator RbsR compare
BWI76_RS24575 +1.7 2.4 hypothetical protein compare
BWI76_RS27425 +1.7 3.9 DNA-directed RNA polymerase subunit omega compare
BWI76_RS07815 +1.6 1.4 hypothetical protein compare
BWI76_RS00290 +1.4 5.8 Ribokinase (EC 2.7.1.15) (from data) compare
BWI76_RS17980 +1.4 4.5 RNA chaperone ProQ compare
BWI76_RS13420 +1.3 2.7 ABC transporter permease compare
BWI76_RS01585 +1.3 6.2 transcriptional regulator compare
BWI76_RS15135 +1.3 4.0 hypothetical protein compare
BWI76_RS13280 +1.3 8.8 LysR family transcriptional regulator compare
BWI76_RS11430 +1.3 1.9 lipoprotein compare
BWI76_RS15215 +1.3 1.7 N-acetyltransferase compare
BWI76_RS18770 +1.3 1.7 DNA gyrase inhibitor compare
BWI76_RS08275 +1.2 2.4 LexA regulated protein compare
BWI76_RS27395 +1.2 4.6 hypothetical protein compare
BWI76_RS01350 +1.2 1.6 NAD(P)H-flavin reductase compare
BWI76_RS20430 +1.2 4.1 penicillin-insensitive murein endopeptidase compare
BWI76_RS05555 +1.2 2.8 Crl family RNA polymerase assembly factor compare
BWI76_RS25065 +1.2 2.2 polyribonucleotide nucleotidyltransferase compare
BWI76_RS07465 +1.2 2.7 TetR family transcriptional regulator compare
BWI76_RS00430 +1.1 5.7 GNAT family N-acetyltransferase compare
BWI76_RS05235 +1.1 1.9 hypothetical protein compare
BWI76_RS01540 +1.1 2.5 thiamine biosynthesis protein ThiS compare
BWI76_RS06405 +1.1 1.8 2-dehydropantoate 2-reductase compare
BWI76_RS04455 +1.1 1.2 triphosphoribosyl-dephospho-CoA synthase CitG compare
BWI76_RS14390 +1.1 1.3 hypothetical protein compare
BWI76_RS25975 +1.1 4.2 phosphoribulokinase compare
BWI76_RS22935 +1.0 2.1 L-fucose mutarotase compare
BWI76_RS02930 +1.0 1.2 anaerobic ribonucleoside-triphosphate reductase activating protein compare
BWI76_RS19310 +1.0 2.9 ABC transporter permease compare
BWI76_RS14155 +1.0 2.7 transketolase compare
BWI76_RS08340 +1.0 3.7 MFS transporter compare
BWI76_RS13685 +1.0 2.8 IclR family transcriptional regulator compare
BWI76_RS15015 +1.0 1.5 DUF2132 domain-containing protein compare
BWI76_RS24920 +1.0 2.0 YraN family protein compare
BWI76_RS01560 +1.0 2.6 Rsd/AlgQ family anti-sigma factor compare
BWI76_RS21565 +1.0 1.5 outer membrane protein assembly factor BamE compare
BWI76_RS11255 +1.0 1.4 putrescine/spermidine ABC transporter ATP-binding protein compare
BWI76_RS06805 +0.9 1.8 primosomal replication protein N'' compare
BWI76_RS13785 +0.9 2.5 ABC transporter permease compare
BWI76_RS12800 +0.9 1.0 hypothetical protein compare
BWI76_RS01995 +0.9 1.2 AraC family transcriptional regulator compare
BWI76_RS05465 +0.9 1.4 amidohydrolase compare
BWI76_RS25970 +0.9 2.9 hypothetical protein compare
BWI76_RS22645 +0.9 4.2 RNA polymerase sigma factor RpoS compare
BWI76_RS26410 +0.9 2.0 membrane protein compare
BWI76_RS05950 +0.9 1.8 polar amino acid ABC transporter inner membrane subunit compare
BWI76_RS17570 +0.9 2.1 iron-sulfur-binding protein compare
BWI76_RS13275 +0.9 2.2 hypothetical protein compare
BWI76_RS20750 +0.9 1.2 carboxysome structural protein EutK compare
BWI76_RS06540 +0.9 2.1 DNA-binding protein HU-beta compare
BWI76_RS01580 +0.9 1.8 hypothetical protein compare
BWI76_RS22640 +0.9 2.1 hypothetical protein compare
BWI76_RS18270 +0.9 2.5 hypothetical protein compare
BWI76_RS21130 +0.9 2.1 Fe-S assembly protein IscX compare
BWI76_RS16370 +0.9 1.9 electron transport complex subunit D compare
BWI76_RS15775 +0.8 2.2 replication protein compare
BWI76_RS18070 +0.8 2.2 DNA polymerase III subunit epsilon compare
BWI76_RS16355 +0.8 2.1 electron transport complex subunit A compare
BWI76_RS14320 +0.8 2.1 hypothetical protein compare
BWI76_RS25545 +0.8 2.7 hypothetical protein compare
BWI76_RS19195 +0.8 2.6 nickel ABC transporter permease compare
BWI76_RS10795 +0.8 4.6 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) (from data) compare
BWI76_RS16470 +0.8 1.4 transcriptional repressor NemR compare
BWI76_RS15345 +0.8 3.9 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase compare
BWI76_RS20720 +0.8 0.9 hypothetical protein compare
BWI76_RS14770 +0.8 1.2 PTS IIA 2 domain protein compare
BWI76_RS05335 +0.8 1.7 copper homeostasis/adhesion lipoprotein NlpE compare
BWI76_RS11735 +0.8 2.0 PTS N,N'-diacetylchitobiose transporter subunit IIA compare
BWI76_RS15295 +0.8 2.3 MDR efflux pump AcrAB transcriptional activator MarA compare
BWI76_RS16375 +0.7 1.9 electron transport complex subunit G compare
BWI76_RS12780 +0.7 2.1 hypothetical protein compare
BWI76_RS26890 +0.7 1.6 hypothetical protein compare
BWI76_RS19835 +0.7 3.8 nucleoid-associated protein YejK compare
BWI76_RS21125 +0.7 1.4 aminopeptidase PepB compare
BWI76_RS21480 +0.7 1.9 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS09865 +0.7 3.5 MBL fold hydrolase compare
BWI76_RS21905 +0.7 2.9 class II aldolase compare
BWI76_RS16485 +0.7 1.3 ribonuclease T compare
BWI76_RS21410 +0.7 3.5 lipoprotein compare
BWI76_RS25415 +0.7 2.9 GntR family transcriptional regulator compare
BWI76_RS21505 +0.7 1.0 hypothetical protein compare
BWI76_RS10745 +0.7 1.0 hypothetical protein compare
BWI76_RS02870 +0.7 2.5 hypothetical protein compare
BWI76_RS18885 +0.7 1.4 nitrogen fixation regulatory protein compare
BWI76_RS13715 +0.7 2.6 2-chlorobenzoate 1 2-dioxygenase electron transfer subunit compare
BWI76_RS07185 +0.7 1.5 hypothetical protein compare
BWI76_RS17930 +0.7 3.1 cold-shock protein CspC compare
BWI76_RS24925 +0.7 1.0 DnaA initiator-associating protein DiaA compare
BWI76_RS23535 +0.7 1.2 hypothetical protein compare
BWI76_RS07830 +0.7 2.7 3-phytase compare
BWI76_RS10475 +0.7 2.3 binding-protein-dependent transport system inner membrane protein compare
BWI76_RS25965 +0.7 3.4 hydrolase compare
BWI76_RS24965 +0.7 2.8 SCP2 domain-containing protein compare
BWI76_RS01065 +0.7 2.8 ATP-dependent RNA helicase RhlB compare
BWI76_RS22185 +0.7 2.7 hypothetical protein compare
BWI76_RS27630 +0.7 2.1 antibiotic biosynthesis monooxygenase compare
BWI76_RS18060 +0.7 1.2 hypothetical protein compare
BWI76_RS16490 +0.7 1.5 glutaredoxin compare
BWI76_RS11520 +0.7 0.8 hypothetical protein compare
BWI76_RS03105 +0.7 0.9 myo-inosose-2 dehydratase compare
BWI76_RS05070 +0.7 0.9 type II secretion system protein GspH compare
BWI76_RS04260 +0.7 3.6 peroxide stress protein YaaA compare
BWI76_RS17065 +0.7 3.2 phosphoenolpyruvate synthase compare
BWI76_RS09155 +0.6 2.4 undecaprenyl-diphosphatase compare
BWI76_RS04565 +0.6 1.8 bifunctional tRNA pseudouridine(32) synthase/ribosomal large subunit pseudouridine synthase RluA compare
BWI76_RS26285 +0.6 2.2 glycerophosphodiester phosphodiesterase compare
BWI76_RS09560 +0.6 1.1 DoxX family membrane protein compare
BWI76_RS11675 +0.6 1.1 arginine N-succinyltransferase compare
BWI76_RS13315 +0.6 1.5 50S ribosomal protein L7/L12-serine acetyltransferase compare
BWI76_RS25070 +0.6 1.1 hypothetical protein compare
BWI76_RS24540 +0.6 1.0 hypothetical protein compare
BWI76_RS17200 +0.6 1.1 hypothetical protein compare
BWI76_RS08735 +0.6 1.6 Urocanate hydratase (EC 4.2.1.49) (from data) compare
BWI76_RS19470 +0.6 1.5 DNA-binding response regulator compare
BWI76_RS08600 +0.6 3.4 3-deoxy-7-phosphoheptulonate synthase compare
BWI76_RS12865 +0.6 1.7 acetylornithine deacetylase compare
BWI76_RS16360 +0.6 1.1 electron transport complex subunit RsxB compare
BWI76_RS09820 +0.6 1.8 hypothetical protein compare
BWI76_RS20890 +0.6 2.9 neutral zinc metallopeptidase compare
BWI76_RS11935 +0.6 2.4 YmiA family putative membrane protein compare
BWI76_RS15930 +0.6 1.5 dimethylsulfoxide reductase, chain B compare
BWI76_RS08750 +0.6 1.0 kinase inhibitor compare
BWI76_RS20730 +0.6 1.3 hypothetical protein compare
BWI76_RS10045 +0.6 2.7 23S rRNA (cytosine(1962)-C(5))-methyltransferase compare
BWI76_RS24385 +0.6 3.8 phosphodiesterase compare
BWI76_RS16015 +0.6 1.9 pheromone autoinducer 2 transporter compare
BWI76_RS15030 +0.6 1.9 ABC transporter compare
BWI76_RS11150 +0.6 0.8 membrane protein compare
BWI76_RS02825 +0.6 2.5 putative acyltransferase domain protein compare
BWI76_RS17080 +0.6 1.7 hypothetical protein compare
BWI76_RS03610 +0.6 1.1 hypothetical protein compare
BWI76_RS24945 +0.6 0.8 glutamine amidotransferase compare
BWI76_RS11990 +0.6 3.1 exoribonuclease II compare
BWI76_RS17510 +0.6 1.1 selenium metabolism hydrolase compare
BWI76_RS01900 +0.6 2.0 tRNA-dihydrouridine synthase A compare
BWI76_RS14460 +0.6 2.1 MurR/RpiR family transcriptional regulator compare
BWI76_RS07750 +0.6 1.3 2,3-dihydroxybenzoate-AMP ligase compare
BWI76_RS20940 +0.6 1.8 uracil/xanthine transporter compare
BWI76_RS22955 +0.6 1.5 transcriptional regulator GcvA compare
BWI76_RS19870 +0.6 1.8 malate:quinone oxidoreductase compare
BWI76_RS14510 +0.6 1.1 MFS transporter compare
BWI76_RS16550 +0.6 1.8 tRNA-Val compare
BWI76_RS10815 +0.6 2.1 iron permease compare
BWI76_RS09505 +0.6 1.4 arginine transporter permease subunit ArtM compare
BWI76_RS11810 +0.6 0.8 outer membrane protein OmpW compare
BWI76_RS26750 +0.6 1.6 PfkB domain-containing protein compare
BWI76_RS22820 +0.6 1.8 glycerate kinase compare
BWI76_RS07895 +0.6 1.7 sugar ABC transporter ATPase compare
BWI76_RS00720 +0.6 1.0 DNA-binding response regulator compare
BWI76_RS27865 +0.6 1.9 hypothetical protein compare
BWI76_RS05985 +0.6 2.5 branched-chain amino acid ABC transporter permease compare
BWI76_RS19805 +0.6 1.9 Bcr/CflA family multidrug efflux MFS transporter compare
BWI76_RS20605 +0.6 1.9 purine-nucleoside phosphorylase compare
BWI76_RS17860 +0.5 1.1 YoaH family protein compare
BWI76_RS03515 +0.5 1.1 hypothetical protein compare
BWI76_RS03025 +0.5 1.4 N-acetyltransferase compare
BWI76_RS05975 +0.5 1.5 ABC transporter ATP-binding protein compare
BWI76_RS20885 +0.5 2.6 tRNA(Met) cytidine acetyltransferase TmcA compare
BWI76_RS25655 +0.5 1.6 DNA topoisomerase type IA zn finger domain-containing protein compare
BWI76_RS14755 +0.5 1.9 SIS domain-containing protein compare
BWI76_RS01815 +0.5 2.8 phosphate-starvation-inducible protein PsiE compare
BWI76_RS18130 +0.5 0.9 zinc ABC transporter substrate-binding protein compare
BWI76_RS19900 +0.5 2.1 FAD:protein FMN transferase compare
BWI76_RS07200 +0.5 1.6 MFS transporter compare
BWI76_RS16210 +0.5 1.1 hypothetical protein compare
BWI76_RS23595 +0.5 2.1 N-acetyltransferase compare
BWI76_RS19585 +0.5 1.2 gentisate 1,2-dioxygenase compare
BWI76_RS19105 +0.5 2.6 GalU regulator GalF compare
BWI76_RS25695 +0.5 2.2 ribosome alternative rescue factor ArfA compare
BWI76_RS02950 +0.5 1.5 6-phospho-beta-glucosidase compare
BWI76_RS15435 +0.5 1.0 hypothetical protein compare
BWI76_RS26660 +0.5 1.9 transcription elongation factor GreB compare
BWI76_RS22620 +0.5 1.0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase compare
BWI76_RS20560 +0.5 1.1 hypothetical protein compare
BWI76_RS13970 +0.5 0.9 ABC transporter compare
BWI76_RS26945 +0.5 1.7 hypothetical protein compare
BWI76_RS13845 +0.5 1.7 LysR family transcriptional regulator compare
BWI76_RS16120 +0.5 1.1 4-carboxymuconolactone decarboxylase compare
BWI76_RS10540 +0.5 1.6 allantoinase compare
BWI76_RS26150 +0.5 2.0 molecular chaperone Hsp33 compare
BWI76_RS19755 +0.5 1.7 fructuronate reductase compare
BWI76_RS16055 +0.5 1.6 malonate decarboxylase subunit epsilon compare
BWI76_RS20565 +0.5 0.8 hypothetical protein compare
BWI76_RS17165 +0.5 2.1 hypothetical protein compare
BWI76_RS19850 +0.5 1.1 tRNA-Pro compare
BWI76_RS21445 +0.5 1.1 hypothetical protein compare
BWI76_RS06520 +0.5 1.7 trigger factor compare
BWI76_RS03185 +0.5 2.6 CI repressor compare
BWI76_RS12445 +0.5 2.0 phage shock protein operon transcriptional activator compare
BWI76_RS00570 +0.5 3.3 AzlC family protein compare
BWI76_RS25005 +0.5 3.0 biotin-independent malonate decarboxylase subunit beta compare
BWI76_RS07755 +0.5 2.0 isochorismatase compare
BWI76_RS27780 +0.5 1.4 hypothetical protein compare
BWI76_RS14065 +0.5 0.8 hypothetical protein compare


Specific Phenotypes

For 16 genes in this experiment

For carbon source L-Glutamine in Klebsiella michiganensis M5al

For carbon source L-Glutamine across organisms