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Experiment set5IT013 for
Methanococcus maripaludis S2
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Formate McCas no stress control 1
200 most detrimental genes:
gene
name
fitness
t score
description
MMP
_RS08595
+1.1
2.8
flagellar protein C
compare
MMP
_RS07820
+1.0
5.1
UPF0104 family protein
compare
MMP
_RS01370
+0.9
7.7
acetate--CoA ligase family protein
compare
MMP
_RS05535
+0.7
3.8
hypothetical protein
compare
MMP
_RS07875
+0.7
4.2
hypothetical protein
compare
MMP
_RS07115
+0.7
5.8
MBL fold metallo-hydrolase
compare
MMP
_RS00520
+0.6
1.2
RNA polymerase Rpb4 family protein
compare
MMP
_RS08155
+0.6
4.3
hypothetical protein
compare
MMP
_RS00825
+0.6
3.0
fumarylacetoacetate hydrolase family protein
compare
MMP
_RS06155
+0.6
2.9
DUF4186 domain-containing protein
compare
MMP
_RS04520
+0.5
2.8
nucleoside deaminase
compare
MMP
_RS05640
+0.5
3.2
UTP--glucose-1-phosphate uridylyltransferase GalU
compare
MMP
_RS07345
+0.5
3.4
glycine synthesis protein GlyXL
(from data)
compare
MMP
_RS01545
+0.5
0.9
CBS domain-containing protein
compare
MMP
_RS01775
+0.5
2.0
TIGR00297 family protein
compare
MMP
_RS01955
+0.5
2.1
hypothetical protein
compare
MMP
_RS01525
+0.5
1.9
nucleoside-diphosphate kinase
compare
MMP
_RS08660
+0.5
3.4
DHH family phosphoesterase
compare
MMP
_RS02790
+0.5
1.2
class III signal peptide-containing protein
compare
MMP
_RS03465
+0.5
1.2
adenine phosphoribosyltransferase
compare
MMP
_RS01540
+0.5
2.3
DUF504 domain-containing protein
compare
MMP
_RS00530
+0.4
3.6
tRNA pseudouridine(54/55) synthase Pus10
compare
MMP
_RS08275
+0.4
3.8
hypothetical protein
compare
MMP
_RS01930
+0.4
3.5
hypothetical protein
compare
MMP
_RS05580
+0.4
3.9
glycosyltransferase
compare
MMP
_RS06535
+0.4
2.2
2-oxoacid:acceptor oxidoreductase family protein
compare
MMP
_RS03110
+0.4
1.9
glycosyltransferase family 2 protein
compare
MMP
_RS04195
+0.4
1.6
flavodoxin
compare
MMP
_RS08315
+0.4
1.3
S-methyl-5-thioribose-1-phosphate isomerase
compare
MMP
_RS08370
+0.4
0.5
cation:proton antiporter subunit C
compare
MMP
_RS03215
+0.4
3.3
MBL fold metallo-hydrolase
compare
MMP
_RS07330
+0.4
3.4
membrane protein
compare
MMP
_RS08440
+0.4
1.7
cell division protein SepF
compare
MMP
_RS08775
+0.4
2.6
methanogenesis marker 9 domain-containing protein
compare
MMP
_RS06540
+0.4
2.1
3-methyl-2-oxobutanoate dehydrogenase subunit VorB
compare
MMP
_RS01945
+0.4
2.3
DUF4350 domain-containing protein
compare
MMP
_RS08600
+0.4
1.1
flagellar protein D
compare
MMP
_RS06290
+0.4
2.0
DNA repair and recombination protein RadA
compare
MMP
_RS04265
+0.4
1.7
coenzyme F420-reducing hydrogenase FrhD protein
compare
MMP
_RS06555
+0.4
1.7
cupin domain-containing protein
compare
MMP
_RS08310
+0.4
1.3
TMEM165/GDT1 family protein
compare
MMP
_RS01960
+0.4
0.5
hypothetical protein
compare
MMP
_RS01935
+0.4
2.8
DUF58 domain-containing protein
compare
MMP
_RS01895
+0.3
2.7
flippase
compare
MMP
_RS06435
+0.3
2.1
CBS domain-containing protein
compare
MMP
_RS04985
+0.3
1.0
DUF2180 family protein
compare
MMP
_RS04480
+0.3
3.0
lysine 2 3-aminomutase
compare
MMP
_RS01885
+0.3
1.9
Gfo/Idh/MocA family oxidoreductase
compare
MMP
_RS03340
+0.3
0.5
ABC transporter ATP-binding protein
compare
MMP
_RS02475
+0.3
1.2
hypothetical protein
compare
MMP
_RS01910
+0.3
2.4
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMP
_RS06530
+0.3
2.3
bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
compare
MMP
_RS05940
+0.3
2.2
corrinoid protein
compare
MMP
_RS03960
+0.3
0.4
hypothetical protein
compare
MMP
_RS00565
+0.3
1.5
CBS domain-containing protein
compare
MMP
_RS07125
+0.3
1.3
coenzyme F420-reducing hydrogenase FrhD protein
compare
MMP
_RS07925
+0.3
1.4
haloacid dehalogenase
compare
MMP
_RS07420
+0.3
1.7
metalloregulator ArsR/SmtB family transcription factor
compare
MMP
_RS01975
+0.3
2.5
hypothetical protein
compare
MMP
_RS07130
+0.3
2.3
coenzyme F420 hydrogenase subunit gamma
compare
MMP
_RS01900
+0.3
2.3
hypothetical protein
compare
MMP
_RS03910
+0.3
1.0
hypothetical protein
compare
MMP
_RS06575
+0.3
1.8
fluoride efflux transporter CrcB
compare
MMP
_RS01420
+0.3
1.0
hypothetical protein
compare
MMP
_RS01435
+0.3
1.6
DMT family transporter
compare
MMP
_RS06460
+0.3
1.5
pyrimidine dimer DNA glycosylase/endonuclease V
compare
MMP
_RS05720
+0.3
1.7
signal recognition particle subunit SRP19/SEC65 family protein
compare
MMP
_RS07135
+0.3
1.9
coenzyme F420 hydrogenase subunit beta
compare
MMP
_RS08615
+0.3
1.1
flagellar protein G
compare
MMP
_RS01925
+0.3
1.8
DUF1616 domain-containing protein
compare
MMP
_RS03450
+0.3
0.9
glycine synthesis protein GlyXS
(from data)
compare
MMP
_RS03390
+0.3
1.9
malate dehydrogenase
compare
MMP
_RS07900
+0.3
0.8
YeeE/YedE family protein
compare
MMP
_RS06490
+0.3
1.2
hypothetical protein
compare
MMP
_RS01260
+0.3
1.5
HDIG domain-containing protein
compare
MMP
_RS06670
+0.3
1.3
glucose-6-phosphate isomerase
compare
MMP
_RS07410
+0.3
1.8
4-demethylwyosine synthase TYW1
compare
MMP
_RS05990
+0.3
1.7
DsrE family protein
compare
MMP
_RS06550
+0.3
1.5
AMP-binding protein
compare
MMP
_RS07120
+0.3
2.1
coenzyme F420 hydrogenase subunit alpha
compare
MMP
_RS06325
+0.2
0.7
hypothetical protein
compare
MMP
_RS06745
+0.2
1.7
DUF2119 domain-containing protein
compare
MMP
_RS07090
+0.2
1.6
tRNA (adenine-N1)-methyltransferase
compare
MMP
_RS04720
+0.2
0.6
DedA family protein
compare
MMP
_RS00055
+0.2
2.0
DUF2254 domain-containing protein
compare
MMP
_RS08500
+0.2
1.7
pyridoxal 5'-phosphate synthase glutaminase subunit PdxT
compare
MMP
_RS02110
+0.2
1.0
hypothetical protein
compare
MMP
_RS01880
+0.2
1.5
DegT/DnrJ/EryC1/StrS family aminotransferase
compare
MMP
_RS00710
+0.2
1.1
hypothetical protein
compare
MMP
_RS05315
+0.2
0.7
hypothetical protein
compare
MMP
_RS05665
+0.2
1.5
phosphate ABC transporter permease subunit PstC
compare
MMP
_RS02480
+0.2
0.5
hypothetical protein
compare
MMP
_RS00740
+0.2
0.9
cyclase family protein
compare
MMP
_RS06570
+0.2
0.8
DUF190 domain-containing protein
compare
MMP
_RS08705
+0.2
1.6
sulfopyruvate decarboxylase subunit beta
compare
MMP
_RS06480
+0.2
1.6
ABC transporter substrate-binding protein
compare
MMP
_RS04650
+0.2
1.4
tetratricopeptide repeat protein
compare
MMP
_RS00140
+0.2
1.3
DUF192 domain-containing protein
compare
MMP
_RS01725
+0.2
1.1
class I SAM-dependent methyltransferase family protein
compare
MMP
_RS08160
+0.2
1.3
EamA family transporter
compare
MMP
_RS06545
+0.2
1.2
ferredoxin family protein
compare
MMP
_RS03300
+0.2
0.4
TOBE domain-containing protein
compare
MMP
_RS08890
+0.2
1.8
glycosyltransferase family 4 protein
compare
MMP
_RS05635
+0.2
1.4
NAD-dependent epimerase/dehydratase family protein
compare
MMP
_RS05900
+0.2
1.5
tetratricopeptide repeat protein
compare
MMP
_RS04730
+0.2
1.9
flavodoxin family protein
compare
MMP
_RS08760
+0.2
1.0
hypothetical protein
compare
MMP
_RS03585
+0.2
0.7
Hsp20/alpha crystallin family protein
compare
MMP
_RS02690
+0.2
1.2
FmdE family protein
compare
MMP
_RS08215
+0.2
0.8
DUF483 domain-containing protein
compare
MMP
_RS05695
+0.2
1.6
phospholipase D-like domain-containing protein
compare
MMP
_RS01460
+0.2
1.0
hypothetical protein
compare
MMP
_RS02290
+0.2
1.2
MBL fold metallo-hydrolase
compare
MMP
_RS08455
+0.2
1.3
multiprotein bridging factor aMBF1
compare
MMP
_RS06905
+0.2
0.8
hypothetical protein
compare
MMP
_RS08670
+0.2
1.5
metallophosphoesterase
compare
MMP
_RS02085
+0.2
1.4
inosine/xanthosine triphosphatase
compare
MMP
_RS01580
+0.2
1.3
PQQ-binding-like beta-propeller repeat protein
compare
MMP
_RS08175
+0.2
1.3
7-cyano-7-deazaguanine synthase
compare
MMP
_RS01950
+0.2
1.5
hypothetical protein
compare
MMP
_RS02360
+0.2
1.2
hypothetical protein
compare
MMP
_RS03115
+0.2
1.7
hypothetical protein
compare
MMP
_RS08090
+0.2
1.2
hypothetical protein
compare
MMP
_RS05960
+0.2
1.4
CoB--CoM heterodisulfide reductase subunit B
compare
MMP
_RS02905
+0.2
1.2
2-thiouracil desulfurase family protein
compare
MMP
_RS03245
+0.2
1.3
DNA repair and recombination protein RadB
compare
MMP
_RS06275
+0.2
1.3
ATP-dependent DNA helicase
compare
MMP
_RS07800
+0.2
1.3
ATP-binding cassette domain-containing protein
compare
MMP
_RS08580
+0.2
0.6
flagellin
compare
MMP
_RS01905
+0.2
1.4
glycosyltransferase
compare
MMP
_RS03100
+0.2
1.0
hypothetical protein
compare
MMP
_RS03890
+0.2
0.9
DUF2540 domain-containing protein
compare
MMP
_RS05660
+0.2
1.2
phosphate ABC transporter substrate-binding protein
compare
MMP
_RS09050
+0.2
1.1
CAP domain-containing protein
compare
MMP
_RS06445
+0.2
0.6
DUF89 domain-containing protein
compare
MMP
_RS01865
+0.2
0.5
GPR1/FUN34/YaaH family transporter
compare
MMP
_RS07850
+0.2
0.8
prephenate dehydratase
compare
MMP
_RS08575
+0.2
1.5
hypothetical protein
compare
MMP
_RS07185
+0.2
1.4
pyridoxal phosphate-dependent aminotransferase
compare
MMP
_RS04715
+0.2
1.1
CBS domain-containing protein
compare
MMP
_RS01130
+0.2
1.2
flavoprotein
compare
MMP
_RS05715
+0.2
1.2
hypothetical protein
compare
MMP
_RS06520
+0.2
1.0
DUF1786 domain-containing protein
compare
MMP
_RS06185
+0.2
1.3
thermonuclease family protein
compare
MMP
_RS05530
+0.2
1.3
signal peptide peptidase SppA
compare
MMP
_RS01165
+0.2
1.2
DUF434 domain-containing protein
compare
MMP
_RS02970
+0.2
1.5
hypothetical protein
compare
MMP
_RS08840
+0.2
1.3
class I SAM-dependent methyltransferase
compare
MMP
_RS07885
+0.2
0.5
tripartite tricarboxylate transporter permease
compare
MMP
_RS02310
+0.2
0.5
RimK-like ATPgrasp N-terminal domain-containing protein
compare
MMP
_RS07620
+0.2
0.8
energy-coupling factor ABC transporter substrate-binding protein
compare
MMP
_RS08605
+0.2
1.1
flagellar protein E
compare
MMP
_RS01270
+0.2
1.4
prepilin peptidase
compare
MMP
_RS00910
+0.2
1.1
2-phosphosulfolactate phosphatase
compare
MMP
_RS01575
+0.2
0.9
aldolase
compare
MMP
_RS03150
+0.2
1.3
phosphoglycerate mutase
compare
MMP
_RS06910
+0.2
1.3
RlmF-related methyltransferase
compare
MMP
_RS02815
+0.2
0.5
hypothetical protein
compare
MMP
_RS04445
+0.2
1.1
P-II family nitrogen regulator
compare
MMP
_RS01200
+0.2
1.1
hypothetical protein
compare
MMP
_RS01140
+0.2
1.0
molybdate ABC transporter permease subunit
compare
MMP
_RS08590
+0.2
1.2
flagellin
compare
MMP
_RS00660
+0.2
1.3
alkaline phosphatase family protein
compare
MMP
_RS04790
+0.1
0.9
4-hydroxy-tetrahydrodipicolinate reductase
compare
MMP
_RS02960
+0.1
1.0
class I SAM-dependent methyltransferase family protein
compare
MMP
_RS01470
+0.1
0.6
ATP-binding cassette domain-containing protein
compare
MMP
_RS02255
+0.1
1.1
hypothetical protein
compare
MMP
_RS05235
+0.1
1.0
exodeoxyribonuclease III
compare
MMP
_RS03130
+0.1
1.1
hypothetical protein
compare
MMP
_RS07805
+0.1
1.0
ABC transporter permease
compare
MMP
_RS07590
+0.1
1.2
hypothetical protein
compare
MMP
_RS07075
+0.1
0.6
phosphomannomutase/phosphoglucomutase
compare
MMP
_RS09035
+0.1
0.8
hypothetical protein
compare
MMP
_RS01455
+0.1
1.0
nickel pincer cofactor biosynthesis protein LarC
compare
MMP
_RS01655
+0.1
0.8
DsrE family protein
compare
MMP
_RS08480
+0.1
1.1
molybdate ABC transporter substrate-binding protein
compare
MMP
_RS07095
+0.1
0.5
PspC domain-containing protein
compare
MMP
_RS02915
+0.1
0.7
amino acid ABC transporter permease
compare
MMP
_RS08700
+0.1
1.1
hypothetical protein
compare
MMP
_RS02770
+0.1
0.8
hypothetical protein
compare
MMP
_RS03765
+0.1
0.8
CopG family ribbon-helix-helix protein
compare
MMP
_RS01120
+0.1
0.9
permease
compare
MMP
_RS07855
+0.1
1.1
class I SAM-dependent methyltransferase
compare
MMP
_RS07890
+0.1
0.3
OB-fold nucleic acid binding domain-containing protein
compare
MMP
_RS01080
+0.1
0.8
DUF2202 domain-containing protein
compare
MMP
_RS06585
+0.1
0.5
DMT family protein
compare
MMP
_RS01970
+0.1
1.1
TIGR04279 domain-containing protein
compare
MMP
_RS03670
+0.1
0.5
DUF1890 domain-containing protein
compare
MMP
_RS08195
+0.1
0.9
hypothetical protein
compare
MMP
_RS05575
+0.1
1.0
hypothetical protein
compare
MMP
_RS03785
+0.1
0.8
cupin domain-containing protein
compare
MMP
_RS04840
+0.1
0.9
response regulator
compare
MMP
_RS06665
+0.1
1.1
glycogen/starch synthase
compare
MMP
_RS02640
+0.1
1.0
DUF6198 family protein
compare
MMP
_RS07840
+0.1
0.5
ribonuclease III
compare
MMP
_RS02100
+0.1
0.7
metallophosphoesterase
compare
MMP
_RS00945
+0.1
0.3
PadR family transcriptional regulator
compare
MMP
_RS02495
+0.1
0.6
hypothetical protein
compare
MMP
_RS08260
+0.1
0.9
DUF99 family protein
compare
MMP
_RS01920
+0.1
1.1
glycosyltransferase family 2 protein
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis S2 in stress experiments