Experiment set5IT013 for Klebsiella michiganensis M5al

Compare to:

L-Malic acid disodium salt monohydrate carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS20355 -8.2 -5.7 colicin V production protein compare
BWI76_RS00805 -7.6 -5.2 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS18935 -7.1 -8.5 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS20965 -7.0 -5.8 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS05840 -7.0 -4.8 glutamate 5-kinase compare
BWI76_RS18920 -6.9 -4.7 ATP phosphoribosyltransferase compare
BWI76_RS11965 -6.7 -5.7 orotidine-5'-phosphate decarboxylase compare
BWI76_RS04465 -6.7 -4.6 carbamoyl-phosphate synthase small subunit compare
BWI76_RS02815 -6.4 -4.4 fructose-bisphosphatase class I compare
BWI76_RS18930 -6.3 -5.0 histidinol-phosphate transaminase compare
BWI76_RS04670 -6.2 -10.0 3-isopropylmalate dehydratase large subunit compare
BWI76_RS21475 -6.2 -8.4 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS04470 -6.0 -10.8 carbamoyl phosphate synthase large subunit compare
BWI76_RS04255 -6.0 -9.1 threonine synthase compare
BWI76_RS00855 -5.9 -8.1 argininosuccinate lyase compare
BWI76_RS18955 -5.9 -6.1 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS04250 -5.9 -7.1 homoserine kinase compare
BWI76_RS21465 -5.8 -6.5 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS23920 -5.8 -5.6 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS00990 -5.7 -8.7 ketol-acid reductoisomerase compare
BWI76_RS01615 -5.7 -10.9 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS04665 -5.6 -21.3 3-isopropylmalate dehydratase small subunit compare
BWI76_RS18950 -5.6 -5.1 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS26085 -5.5 -3.8 3-dehydroquinate synthase compare
BWI76_RS01655 -5.4 -9.0 homoserine O-succinyltransferase compare
BWI76_RS11855 -5.4 -7.6 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS04685 -5.3 -7.9 putative leucine operon leader peptide compare
BWI76_RS18925 -5.3 -8.9 histidinol dehydrogenase compare
BWI76_RS25115 -5.2 -9.3 argininosuccinate synthase compare
BWI76_RS18940 -5.2 -7.3 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS08385 -5.2 -4.9 citrate (Si)-synthase compare
BWI76_RS04245 -5.2 -14.1 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS05015 -5.2 -4.2 transcriptional regulator compare
BWI76_RS23360 -5.1 -5.0 diaminopimelate decarboxylase compare
BWI76_RS09645 -5.1 -2.1 thioredoxin-disulfide reductase compare
BWI76_RS00980 -5.1 -11.8 PLP-dependent threonine dehydratase compare
BWI76_RS00850 -5.0 -10.5 acetylglutamate kinase compare
BWI76_RS11850 -5.0 -12.4 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS04160 -4.8 -6.3 phosphoserine phosphatase compare
BWI76_RS00785 -4.8 -6.5 cystathionine gamma-synthase compare
BWI76_RS21265 -4.8 -11.8 phosphoribosylformylglycinamidine synthase compare
BWI76_RS24285 -4.8 -6.9 cystathionine beta-lyase compare
BWI76_RS22690 -4.7 -4.0 adenylyl-sulfate kinase compare
BWI76_RS09755 -4.7 -6.2 phosphoserine transaminase compare
BWI76_RS00965 -4.7 -2.0 acetolactate synthase 2 small subunit compare
BWI76_RS01210 -4.7 -3.7 tyrosine recombinase XerC compare
BWI76_RS02995 -4.7 -7.7 aspartate carbamoyltransferase compare
BWI76_RS23220 -4.6 -9.9 amino-acid N-acetyltransferase compare
BWI76_RS20350 -4.6 -9.4 amidophosphoribosyltransferase compare
BWI76_RS04645 -4.6 -6.8 3-dehydroquinase compare
BWI76_RS04680 -4.6 -11.8 2-isopropylmalate synthase compare
BWI76_RS11840 -4.6 -6.0 tryptophan synthase subunit alpha compare
BWI76_RS27385 -4.5 -6.9 orotate phosphoribosyltransferase compare
BWI76_RS02735 -4.5 -6.2 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS07070 -4.5 -6.8 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS15825 -4.4 -2.9 hypothetical protein compare
BWI76_RS09760 -4.4 -7.2 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS07065 -4.4 -8.2 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS11860 -4.3 -9.2 anthranilate synthase component I compare
BWI76_RS09910 -4.3 -16.8 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS11845 -4.3 -2.7 tryptophan synthase subunit beta compare
BWI76_RS03010 -4.3 -7.9 ornithine carbamoyltransferase compare
BWI76_RS22755 -4.3 -6.8 phosphoadenosine phosphosulfate reductase compare
BWI76_RS22760 -4.2 -8.6 sulfite reductase subunit beta compare
BWI76_RS04705 -4.2 -8.5 DNA-binding transcriptional regulator FruR compare
BWI76_RS05835 -4.2 -4.9 gamma-glutamyl-phosphate reductase compare
BWI76_RS04675 -4.1 -3.9 3-isopropylmalate dehydrogenase compare
BWI76_RS00985 -4.1 -6.9 transcriptional regulator IlvY compare
BWI76_RS22765 -4.0 -15.0 sulfite reductase subunit alpha compare
BWI76_RS01610 -4.0 -6.3 phosphoribosylamine--glycine ligase compare
BWI76_RS01200 -4.0 -2.7 diaminopimelate epimerase compare
BWI76_RS00845 -4.0 -8.4 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS23365 -3.9 -5.4 LysR family transcriptional regulator compare
BWI76_RS20435 -3.8 -2.2 chorismate synthase compare
BWI76_RS20895 -3.8 -6.0 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS27390 -3.7 -4.7 ribonuclease PH compare
BWI76_RS00975 -3.7 -5.6 dihydroxy-acid dehydratase compare
BWI76_RS10990 -3.7 -3.4 dihydroorotase compare
BWI76_RS00400 -3.4 -2.2 glutamine synthetase compare
BWI76_RS23240 -3.3 -3.9 exonuclease V subunit gamma compare
BWI76_RS24900 -3.2 -3.1 DeoR family transcriptional regulator compare
BWI76_RS01185 -3.2 -2.2 adenylate cyclase compare
BWI76_RS09615 -3.1 -3.1 ATP-dependent Clp protease ATP-binding subunit ClpA compare
BWI76_RS23230 -3.1 -3.0 exodeoxyribonuclease V subunit beta compare
BWI76_RS00140 -3.1 -1.8 phosphate transport system regulator PhoU compare
BWI76_RS08395 -3.0 -3.0 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS17720 -2.9 -2.4 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS09660 -2.9 -3.2 DNA translocase FtsK compare
BWI76_RS20970 -2.9 -2.3 phosphoribosylglycinamide formyltransferase compare
BWI76_RS04240 -2.8 -3.8 thr operon leader peptide compare
BWI76_RS00180 -2.7 -2.8 F0F1 ATP synthase subunit epsilon compare
BWI76_RS20650 -2.7 -2.6 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS20640 -2.6 -4.3 cysteine synthase A compare
BWI76_RS08535 -2.6 -2.9 translocation protein TolB compare
BWI76_RS26570 -2.5 -3.9 anion permease compare
BWI76_RS26055 -2.5 -7.7 siroheme synthase compare
BWI76_RS12090 -2.4 -3.6 HNH endonuclease compare
BWI76_RS04530 -2.3 -3.7 peptidylprolyl isomerase SurA compare
BWI76_RS23885 -2.3 -2.5 2-octaprenylphenol hydroxylase compare
BWI76_RS25645 -2.1 -7.9 shikimate dehydrogenase compare
BWI76_RS26890 -2.1 -1.8 hypothetical protein compare
BWI76_RS26075 -2.1 -4.6 DNA adenine methylase compare
BWI76_RS08525 -2.0 -4.5 colicin transporter compare
BWI76_RS19010 -2.0 -4.5 polysaccharide pyruvyl transferase yvff compare
BWI76_RS10575 -1.9 -1.9 polar amino acid ABC transporter permease compare
BWI76_RS20440 -1.9 -1.2 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS08405 -1.8 -3.6 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS21100 -1.8 -3.9 nucleoside-diphosphate kinase compare
BWI76_RS08520 -1.8 -3.0 colicin transporter TolQ compare
BWI76_RS06185 -1.8 -7.7 shikimate kinase II compare
BWI76_RS17065 -1.8 -6.6 phosphoenolpyruvate synthase compare
BWI76_RS25335 -1.7 -3.4 stringent starvation protein A compare
BWI76_RS24080 -1.7 -2.3 DUF179 domain-containing protein compare
BWI76_RS03080 -1.7 -4.1 (Fe-S)-cluster assembly protein compare
BWI76_RS26000 -1.6 -5.0 aspartate aminotransferase family protein compare
BWI76_RS05200 -1.6 -2.6 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS19840 -1.6 -1.7 hypothetical protein compare
BWI76_RS27430 -1.6 -1.5 (p)ppGpp synthetase compare
BWI76_RS06730 -1.6 -3.4 lac repressor compare
BWI76_RS27475 -1.5 -8.4 regulatory protein GntR family protein compare
BWI76_RS25420 -1.5 -4.7 malate dehydrogenase compare
BWI76_RS20155 -1.5 -1.6 NADH-quinone oxidoreductase subunit I compare
BWI76_RS21310 -1.5 -1.4 DNA repair protein RecO compare
BWI76_RS22420 -1.5 -2.6 LacI family transcriptional regulator compare
BWI76_RS25065 -1.5 -2.6 polyribonucleotide nucleotidyltransferase compare
BWI76_RS22700 -1.5 -6.0 sulfate adenylyltransferase subunit 2 compare
BWI76_RS02530 -1.5 -2.4 tRNA dimethylallyltransferase compare
BWI76_RS21070 -1.5 -2.8 outer membrane protein assembly factor BamB compare
BWI76_RS07465 -1.4 -3.3 TetR family transcriptional regulator compare
BWI76_RS25320 -1.4 -6.6 glutamate synthase compare
BWI76_RS27440 -1.4 -3.7 DNA helicase RecG compare
BWI76_RS21810 -1.4 -2.2 universal stress protein compare
BWI76_RS01800 -1.4 -3.7 glucose-6-phosphate isomerase compare
BWI76_RS15835 -1.4 -0.9 hypothetical protein compare
BWI76_RS23895 -1.4 -1.6 Xaa-Pro aminopeptidase compare
BWI76_RS15810 -1.4 -4.6 hypothetical protein compare
BWI76_RS26190 -1.4 -3.5 glycerol-3-phosphate dehydrogenase compare
BWI76_RS09190 -1.4 -4.1 hypothetical protein compare
BWI76_RS26760 -1.4 -3.6 C4-dicarboxylate transport protein DctA (from data) compare
BWI76_RS20880 -1.3 -2.0 esterase compare
BWI76_RS27875 -1.3 -1.6 membrane protein compare
BWI76_RS15600 -1.3 -2.6 hypothetical protein compare
BWI76_RS17290 -1.3 -2.5 formyltetrahydrofolate deformylase compare
BWI76_RS11980 -1.3 -2.1 DeoR family transcriptional regulator compare
BWI76_RS23480 -1.3 -8.0 EAL domain-containing protein compare
BWI76_RS21140 -1.3 -2.6 molecular chaperone HscA compare
BWI76_RS22240 -1.2 -6.7 transcriptional regulator compare
BWI76_RS15830 -1.2 -2.2 hypothetical protein compare
BWI76_RS00345 -1.2 -2.5 protein disulfide oxidoreductase DsbA compare
BWI76_RS26620 -1.2 -1.3 Fe-S biogenesis protein NfuA compare
BWI76_RS19375 -1.2 -2.3 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase compare
BWI76_RS22695 -1.2 -4.0 sulfate adenylyltransferase compare
BWI76_RS13820 -1.2 -2.2 hypothetical protein compare
BWI76_RS15955 -1.2 -4.8 transcriptional regulator compare
BWI76_RS00960 -1.2 -4.0 acetolactate synthase 2 catalytic subunit compare
BWI76_RS04270 -1.2 -3.8 transaldolase compare
BWI76_RS17975 -1.2 -3.6 tail-specific protease compare
BWI76_RS03225 -1.1 -6.2 transcriptional regulator compare
BWI76_RS00440 -1.1 -1.4 CopG family transcriptional regulator compare
BWI76_RS25315 -1.1 -6.2 glutamate synthase large subunit compare
BWI76_RS25600 -1.1 -1.1 tRNA-Thr compare
BWI76_RS15225 -1.1 -3.9 DeoR family transcriptional regulator compare
BWI76_RS27075 -1.1 -3.5 IclR family transcriptional regulator compare
BWI76_RS20910 -1.1 -3.7 glycine cleavage system transcriptional repressor compare
BWI76_RS07675 -1.0 -4.1 DeoR family transcriptional regulator compare
BWI76_RS00390 -1.0 -2.3 two-component system sensor histidine kinase NtrB compare
BWI76_RS16315 -1.0 -2.0 SirA-like protein compare
BWI76_RS19475 -1.0 -3.9 signal transduction histidine kinase compare
BWI76_RS00385 -1.0 -5.2 nitrogen assimilation regulatory protein compare
BWI76_RS03105 -1.0 -1.0 myo-inosose-2 dehydratase compare
BWI76_RS18385 -1.0 -1.3 hypothetical protein compare
BWI76_RS01220 -1.0 -4.5 DNA-dependent helicase II compare
BWI76_RS13320 -1.0 -2.6 putative LpxA-like enzyme compare
BWI76_RS15680 -1.0 -2.8 hypothetical protein compare
BWI76_RS02610 -1.0 -4.5 transcriptional regulator compare
BWI76_RS26175 -1.0 -2.5 DeoR/GlpR family transcriptional regulator compare
BWI76_RS08700 -1.0 -4.6 helix-turn-helix-type transcriptional regulator compare
BWI76_RS11260 -1.0 -1.9 hypothetical protein compare
BWI76_RS07730 -1.0 -1.3 iron-enterobactin transporter membrane protein compare
BWI76_RS07790 -1.0 -2.0 plasmid stabilization protein compare
BWI76_RS18165 -1.0 -1.6 NUDIX pyrophosphatase compare
BWI76_RS04715 -1.0 -1.5 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS04525 -1.0 -1.2 4-hydroxythreonine-4-phosphate dehydrogenase PdxA compare
BWI76_RS14615 -1.0 -1.4 hypothetical protein compare
BWI76_RS09655 -1.0 -4.1 leucine-responsive regulatory protein compare
BWI76_RS19495 -1.0 -1.3 ABC transporter, quaternary amine uptake transporter (QAT) family, ATP-binding protein compare
BWI76_RS01775 -1.0 -1.1 hypothetical protein compare
BWI76_RS13435 -0.9 -1.7 hypothetical protein compare
BWI76_RS21505 -0.9 -1.0 hypothetical protein compare
BWI76_RS07725 -0.9 -1.2 iron-enterobactin transporter permease compare
BWI76_RS23915 -0.9 -1.6 5-formyltetrahydrofolate cyclo-ligase compare
BWI76_RS00765 -0.9 -3.5 DNA-binding transcriptional regulator CytR compare
BWI76_RS21690 -0.9 -1.6 hypothetical protein compare
BWI76_RS24850 -0.9 -4.6 DeoR family transcriptional regulator compare
BWI76_RS26665 -0.9 -2.0 DNA-binding response regulator compare
BWI76_RS26390 -0.9 -3.1 cell division protein FtsX compare
BWI76_RS01350 -0.9 -0.8 NAD(P)H-flavin reductase compare
BWI76_RS15685 -0.9 -2.1 hypothetical protein compare
BWI76_RS08530 -0.9 -2.1 protein TolA compare
BWI76_RS26405 -0.9 -1.3 16S rRNA (guanine(966)-N(2))-methyltransferase compare


Specific Phenotypes

None in this experiment

For Klebsiella michiganensis M5al in carbon source experiments

For carbon source L-Malic acid disodium salt monohydrate across organisms