Experiment set5IT011 for Klebsiella michiganensis M5al

Compare to:

D-Sorbitol carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS18930 -9.2 -6.3 histidinol-phosphate transaminase compare
BWI76_RS18925 -7.7 -5.3 histidinol dehydrogenase compare
BWI76_RS00805 -7.6 -5.2 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS04250 -7.1 -6.9 homoserine kinase compare
BWI76_RS18920 -6.9 -4.7 ATP phosphoribosyltransferase compare
BWI76_RS04255 -6.7 -6.5 threonine synthase compare
BWI76_RS04465 -6.7 -4.6 carbamoyl-phosphate synthase small subunit compare
BWI76_RS21475 -6.7 -7.4 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS18950 -6.7 -6.5 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS22755 -6.4 -7.7 phosphoadenosine phosphosulfate reductase compare
BWI76_RS04685 -6.3 -11.4 putative leucine operon leader peptide compare
BWI76_RS04670 -6.3 -9.7 3-isopropylmalate dehydratase large subunit compare
BWI76_RS04245 -6.3 -12.8 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS05835 -6.3 -4.3 gamma-glutamyl-phosphate reductase compare
BWI76_RS20965 -6.1 -5.4 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS11965 -6.1 -4.8 orotidine-5'-phosphate decarboxylase compare
BWI76_RS01655 -6.0 -8.8 homoserine O-succinyltransferase compare
BWI76_RS00850 -6.0 -9.6 acetylglutamate kinase compare
BWI76_RS18935 -6.0 -8.5 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS23920 -5.9 -5.7 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS23360 -5.9 -4.0 diaminopimelate decarboxylase compare
BWI76_RS00990 -5.8 -8.2 ketol-acid reductoisomerase compare
BWI76_RS21465 -5.7 -5.8 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS23220 -5.7 -8.7 amino-acid N-acetyltransferase compare
BWI76_RS00835 -5.7 -14.3 phosphoenolpyruvate carboxylase compare
BWI76_RS10990 -5.7 -3.6 dihydroorotase compare
BWI76_RS20350 -5.7 -9.5 amidophosphoribosyltransferase compare
BWI76_RS11850 -5.7 -11.8 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS20895 -5.7 -6.7 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS05840 -5.6 -6.7 glutamate 5-kinase compare
BWI76_RS24285 -5.6 -7.0 cystathionine beta-lyase compare
BWI76_RS11840 -5.5 -3.0 tryptophan synthase subunit alpha compare
BWI76_RS26085 -5.5 -3.8 3-dehydroquinate synthase compare
BWI76_RS01210 -5.5 -4.6 tyrosine recombinase XerC compare
BWI76_RS04665 -5.4 -21.2 3-isopropylmalate dehydratase small subunit compare
BWI76_RS02995 -5.4 -8.3 aspartate carbamoyltransferase compare
BWI76_RS25115 -5.3 -7.7 argininosuccinate synthase compare
BWI76_RS00845 -5.2 -10.5 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS22760 -5.2 -8.9 sulfite reductase subunit beta compare
BWI76_RS00855 -5.2 -9.9 argininosuccinate lyase compare
BWI76_RS08385 -5.2 -5.0 citrate (Si)-synthase compare
BWI76_RS18940 -5.2 -6.6 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS04645 -5.1 -7.8 3-dehydroquinase compare
BWI76_RS09645 -5.1 -2.3 thioredoxin-disulfide reductase compare
BWI76_RS23365 -5.1 -5.8 LysR family transcriptional regulator compare
BWI76_RS11860 -5.0 -9.9 anthranilate synthase component I compare
BWI76_RS11855 -5.0 -9.3 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS04470 -5.0 -9.1 carbamoyl phosphate synthase large subunit compare
BWI76_RS01615 -5.0 -12.0 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS00980 -5.0 -12.4 PLP-dependent threonine dehydratase compare
BWI76_RS04680 -4.9 -12.6 2-isopropylmalate synthase compare
BWI76_RS21265 -4.9 -13.3 phosphoribosylformylglycinamidine synthase compare
BWI76_RS09755 -4.9 -5.5 phosphoserine transaminase compare
BWI76_RS18955 -4.9 -5.1 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS00965 -4.8 -2.1 acetolactate synthase 2 small subunit compare
BWI76_RS00985 -4.7 -7.2 transcriptional regulator IlvY compare
BWI76_RS00785 -4.7 -6.4 cystathionine gamma-synthase compare
BWI76_RS00975 -4.7 -8.1 dihydroxy-acid dehydratase compare
BWI76_RS22220 -4.6 -9.3 PTS glucitol/sorbitol transporter subunit IIB compare
BWI76_RS22690 -4.6 -5.4 adenylyl-sulfate kinase compare
BWI76_RS04160 -4.5 -7.0 phosphoserine phosphatase compare
BWI76_RS09910 -4.4 -18.4 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS04675 -4.4 -6.9 3-isopropylmalate dehydrogenase compare
BWI76_RS27385 -4.4 -7.9 orotate phosphoribosyltransferase compare
BWI76_RS07065 -4.3 -5.1 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS01610 -4.3 -5.9 phosphoribosylamine--glycine ligase compare
BWI76_RS04240 -4.3 -2.0 thr operon leader peptide compare
BWI76_RS09760 -4.3 -4.1 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS22215 -4.2 -8.4 PTS sorbitol transporter subunit IIC compare
BWI76_RS22765 -4.2 -16.7 sulfite reductase subunit alpha compare
BWI76_RS05015 -4.1 -3.9 transcriptional regulator compare
BWI76_RS26460 -4.1 -5.8 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS09660 -4.0 -2.7 DNA translocase FtsK compare
BWI76_RS27165 -4.0 -4.8 mannitol-1-phosphate 5-dehydrogenase compare
BWI76_RS11845 -4.0 -3.4 tryptophan synthase subunit beta compare
BWI76_RS22230 -4.0 -7.0 Sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140) (from data) conserved
BWI76_RS26455 -3.9 -4.6 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS03010 -3.8 -6.7 ornithine carbamoyltransferase compare
BWI76_RS23240 -3.8 -3.7 exonuclease V subunit gamma compare
BWI76_RS22225 -3.8 -7.6 PTS sorbitol transporter subunit IIA compare
BWI76_RS27390 -3.7 -4.1 ribonuclease PH compare
BWI76_RS07070 -3.7 -3.3 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS20355 -3.5 -5.1 colicin V production protein compare
BWI76_RS17720 -3.4 -2.5 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS26055 -3.3 -7.9 siroheme synthase compare
BWI76_RS25645 -3.3 -9.3 shikimate dehydrogenase compare
BWI76_RS01185 -3.2 -2.2 adenylate cyclase compare
BWI76_RS25320 -3.2 -10.7 glutamate synthase compare
BWI76_RS02735 -3.1 -4.1 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS20650 -3.0 -2.1 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS20435 -3.0 -2.5 chorismate synthase compare
BWI76_RS22805 -3.0 -9.6 GTP diphosphokinase compare
BWI76_RS25315 -2.8 -13.4 glutamate synthase large subunit compare
BWI76_RS00400 -2.8 -2.6 glutamine synthetase compare
BWI76_RS01200 -2.7 -3.2 diaminopimelate epimerase compare
BWI76_RS15825 -2.7 -4.5 hypothetical protein compare
BWI76_RS23230 -2.4 -4.0 exodeoxyribonuclease V subunit beta compare
BWI76_RS02530 -2.4 -3.3 tRNA dimethylallyltransferase compare
BWI76_RS00390 -2.4 -5.5 two-component system sensor histidine kinase NtrB compare
BWI76_RS20640 -2.4 -4.9 cysteine synthase A compare
BWI76_RS26000 -2.4 -9.2 aspartate aminotransferase family protein compare
BWI76_RS05200 -2.2 -3.1 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS00180 -2.1 -2.8 F0F1 ATP synthase subunit epsilon compare
BWI76_RS20970 -2.0 -2.3 phosphoribosylglycinamide formyltransferase compare
BWI76_RS00385 -2.0 -9.3 nitrogen assimilation regulatory protein compare
BWI76_RS20440 -2.0 -2.2 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS18165 -2.0 -2.7 NUDIX pyrophosphatase compare
BWI76_RS20380 -1.9 -1.8 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS26570 -1.9 -3.0 anion permease compare
BWI76_RS21100 -1.8 -4.3 nucleoside-diphosphate kinase compare
BWI76_RS25425 -1.8 -2.4 arginine repressor compare
BWI76_RS01385 -1.8 -3.3 potassium transporter compare
BWI76_RS23480 -1.7 -11.2 EAL domain-containing protein compare
BWI76_RS16965 -1.7 -3.4 murein lipoprotein compare
BWI76_RS26470 -1.7 -5.7 4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase compare
BWI76_RS09655 -1.6 -6.8 leucine-responsive regulatory protein compare
BWI76_RS04510 -1.6 -2.4 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS06185 -1.6 -8.3 shikimate kinase II compare
BWI76_RS05570 -1.6 -1.6 hypothetical protein compare
BWI76_RS24900 -1.5 -2.0 DeoR family transcriptional regulator compare
BWI76_RS07730 -1.5 -1.8 iron-enterobactin transporter membrane protein compare
BWI76_RS02985 -1.5 -2.3 reactive intermediate/imine deaminase compare
BWI76_RS19690 -1.5 -3.1 LysR family transcriptional regulator compare
BWI76_RS15835 -1.4 -1.0 hypothetical protein compare
BWI76_RS27440 -1.4 -3.6 DNA helicase RecG compare
BWI76_RS21580 -1.4 -2.0 SsrA-binding protein compare
BWI76_RS00345 -1.3 -1.9 protein disulfide oxidoreductase DsbA compare
BWI76_RS10745 -1.3 -1.4 hypothetical protein compare
BWI76_RS26620 -1.3 -1.4 Fe-S biogenesis protein NfuA compare
BWI76_RS16315 -1.3 -2.0 SirA-like protein compare
BWI76_RS00960 -1.2 -3.8 acetolactate synthase 2 catalytic subunit compare
BWI76_RS16485 -1.2 -1.7 ribonuclease T compare
BWI76_RS04530 -1.2 -2.0 peptidylprolyl isomerase SurA compare
BWI76_RS15840 -1.2 -2.7 prophage protein compare
BWI76_RS21140 -1.2 -1.9 molecular chaperone HscA compare
BWI76_RS15830 -1.1 -2.4 hypothetical protein compare
BWI76_RS22235 -1.1 -2.5 transcriptional regulator GutM compare
BWI76_RS06530 -1.1 -4.9 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS26075 -1.1 -2.3 DNA adenine methylase compare
BWI76_RS19585 -1.1 -1.4 gentisate 1,2-dioxygenase compare
BWI76_RS17980 -1.1 -3.0 RNA chaperone ProQ compare
BWI76_RS04095 -1.1 -1.5 dUMP phosphatase compare
BWI76_RS05260 -1.1 -1.6 chaperone compare
BWI76_RS23895 -1.0 -0.9 Xaa-Pro aminopeptidase compare
BWI76_RS24025 -1.0 -5.3 agmatinase compare
BWI76_RS22695 -1.0 -3.4 sulfate adenylyltransferase compare
BWI76_RS06295 -1.0 -4.9 S-adenosylmethionine:tRNA ribosyltransferase-isomerase compare
BWI76_RS04715 -1.0 -1.5 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS20995 -1.0 -2.6 RNA degradosome polyphosphate kinase compare
BWI76_RS04515 -1.0 -1.5 Co2+/Mg2+ efflux protein ApaG compare
BWI76_RS15760 -1.0 -1.8 hypothetical protein compare
BWI76_RS12090 -1.0 -1.1 HNH endonuclease compare
BWI76_RS17290 -1.0 -4.2 formyltetrahydrofolate deformylase compare
BWI76_RS02725 -1.0 -1.0 HxlR family transcriptional regulator compare
BWI76_RS05880 -1.0 -2.1 AraC-type DNA-binding domain-containing protein compare
BWI76_RS02990 -1.0 -1.9 aspartate carbamoyltransferase regulatory subunit compare
BWI76_RS21370 -1.0 -1.4 ATP-dependent RNA helicase SrmB compare
BWI76_RS22085 -1.0 -2.5 L-valine transporter subunit YgaH compare
BWI76_RS16955 -1.0 -1.5 hypothetical protein compare
BWI76_RS21480 -0.9 -2.6 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS08395 -0.9 -1.8 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS17975 -0.9 -3.3 tail-specific protease compare
BWI76_RS04525 -0.9 -1.8 4-hydroxythreonine-4-phosphate dehydrogenase PdxA compare
BWI76_RS25335 -0.9 -2.3 stringent starvation protein A compare
BWI76_RS15810 -0.9 -3.6 hypothetical protein compare
BWI76_RS00140 -0.9 -1.0 phosphate transport system regulator PhoU compare
BWI76_RS22700 -0.9 -2.5 sulfate adenylyltransferase subunit 2 compare
BWI76_RS08520 -0.9 -1.8 colicin transporter TolQ compare
BWI76_RS07465 -0.9 -2.2 TetR family transcriptional regulator compare
BWI76_RS25505 -0.9 -3.1 RNase E specificity factor CsrD compare
BWI76_RS19010 -0.9 -2.3 polysaccharide pyruvyl transferase yvff compare
BWI76_RS09970 -0.9 -2.1 porin OmpA compare
BWI76_RS11435 -0.9 -1.5 hypothetical protein compare
BWI76_RS16920 -0.9 -1.6 3-(2,3-dihydroxyphenyl)propionate dioxygenase compare
BWI76_RS13590 -0.9 -2.7 hypothetical protein compare
BWI76_RS15955 -0.9 -5.9 transcriptional regulator compare
BWI76_RS24080 -0.9 -1.4 DUF179 domain-containing protein compare
BWI76_RS16195 -0.9 -1.6 hypothetical protein compare
BWI76_RS25280 -0.9 -1.6 RNase adaptor protein RapZ compare
BWI76_RS17775 -0.8 -2.7 hypothetical protein compare
BWI76_RS21165 -0.8 -1.6 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS17375 -0.8 -1.9 nitrate ABC transporter, permease protein compare
BWI76_RS14835 -0.8 -1.2 hypothetical protein compare
BWI76_RS19840 -0.8 -1.2 hypothetical protein compare
BWI76_RS02410 -0.8 -0.8 EF-P beta-lysylation protein EpmB compare
BWI76_RS15650 -0.8 -3.2 gp5 compare
BWI76_RS12390 -0.8 -1.5 antibiotic biosynthesis monooxygenase compare
BWI76_RS17155 -0.8 -1.3 hypothetical protein compare
BWI76_RS27305 -0.8 -4.2 glycosyl transferase compare
BWI76_RS11980 -0.8 -0.9 DeoR family transcriptional regulator compare
BWI76_RS25065 -0.8 -1.6 polyribonucleotide nucleotidyltransferase compare
BWI76_RS24595 -0.8 -3.9 dihydroxyacetone kinase subunit DhaK compare
BWI76_RS27460 -0.8 -2.5 hypothetical protein compare
BWI76_RS26185 -0.8 -1.4 thiosulfate sulfurtransferase compare
BWI76_RS07705 -0.8 -2.5 enterochelin esterase compare
BWI76_RS19685 -0.8 -3.1 lysine transporter compare
BWI76_RS24955 -0.8 -1.6 hypothetical protein compare
BWI76_RS23580 -0.8 -2.2 hypothetical protein compare
BWI76_RS15060 -0.8 -2.2 MarR family transcriptional regulator compare
BWI76_RS15680 -0.8 -2.8 hypothetical protein compare


Specific Phenotypes

For 4 genes in this experiment

For carbon source D-Sorbitol in Klebsiella michiganensis M5al

For carbon source D-Sorbitol across organisms