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Experiment set5IT010 for
Methanococcus maripaludis S2
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H2 McCas deepwell complete
200 most detrimental genes:
gene
name
fitness
t score
description
MMP
_RS02675
+1.5
4.1
hypothetical protein
compare
MMP
_RS01650
+1.4
1.9
sulfurtransferase TusA family protein
compare
MMP
_RS06485
+1.4
1.8
zinc ribbon domain-containing protein
compare
MMP
_RS02815
+1.1
1.5
hypothetical protein
compare
MMP
_RS01525
+1.1
2.3
nucleoside-diphosphate kinase
compare
MMP
_RS03465
+1.0
1.4
adenine phosphoribosyltransferase
compare
MMP
_RS01570
+1.0
1.7
hypothetical protein
compare
MMP
_RS00655
+0.9
1.4
hypothetical protein
compare
MMP
_RS03300
+0.9
1.0
TOBE domain-containing protein
compare
MMP
_RS07915
+0.9
2.0
DUF4870 domain-containing protein
compare
MMP
_RS01435
+0.9
1.9
DMT family transporter
compare
MMP
_RS02805
+0.9
1.3
HEPN domain-containing protein
compare
MMP
_RS07095
+0.8
1.5
PspC domain-containing protein
compare
MMP
_RS02475
+0.8
1.4
hypothetical protein
compare
MMP
_RS02290
+0.8
2.7
MBL fold metallo-hydrolase
compare
MMP
_RS00395
+0.8
1.5
MGMT family protein
compare
MMP
_RS07970
+0.8
1.3
hypothetical protein
compare
MMP
_RS02110
+0.7
1.1
hypothetical protein
compare
MMP
_RS01545
+0.7
0.6
CBS domain-containing protein
compare
MMP
_RS06460
+0.7
2.4
pyrimidine dimer DNA glycosylase/endonuclease V
compare
MMP
_RS05355
+0.7
0.7
hypothetical protein
compare
MMP
_RS02790
+0.6
0.8
class III signal peptide-containing protein
compare
MMP
_RS02490
+0.6
2.5
hypothetical protein
compare
MMP
_RS07815
+0.6
1.0
DUF2120 domain-containing protein
compare
MMP
_RS05825
+0.6
1.8
peptidyl-prolyl cis-trans isomerase
compare
MMP
_RS06910
+0.6
3.1
RlmF-related methyltransferase
compare
MMP
_RS08310
+0.6
1.3
TMEM165/GDT1 family protein
compare
MMP
_RS07860
+0.6
0.5
hypothetical protein
compare
MMP
_RS06385
+0.6
1.6
hypothetical protein
compare
MMP
_RS04050
+0.6
1.5
hypothetical protein
compare
MMP
_RS02045
+0.6
1.1
tRNA-Met
compare
MMP
_RS07835
+0.6
2.4
TldD/PmbA family protein
compare
MMP
_RS02315
+0.6
2.0
RimK family alpha-L-glutamate ligase
compare
MMP
_RS01140
+0.6
1.8
molybdate ABC transporter permease subunit
compare
MMP
_RS00945
+0.6
0.7
PadR family transcriptional regulator
compare
MMP
_RS06490
+0.5
1.5
hypothetical protein
compare
MMP
_RS07765
+0.5
2.3
sodium:alanine symporter family protein
compare
MMP
_RS08615
+0.5
1.2
flagellar protein G
compare
MMP
_RS05970
+0.5
1.1
class II SORL domain-containing protein
compare
MMP
_RS07890
+0.5
1.5
OB-fold nucleic acid binding domain-containing protein
compare
MMP
_RS05365
+0.5
1.0
23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH
compare
MMP
_RS08410
+0.5
1.7
DUF169 domain-containing protein
compare
MMP
_RS08845
+0.5
2.8
archaellum operon transcriptional activator EarA family protein
compare
MMP
_RS08385
+0.5
1.7
ABC transporter substrate-binding protein
compare
MMP
_RS01055
+0.5
1.0
hypothetical protein
compare
MMP
_RS05675
+0.5
1.4
phosphate ABC transporter ATP-binding protein PstB
compare
MMP
_RS08250
+0.5
2.3
pyruvate kinase
compare
MMP
_RS02590
+0.5
1.9
low molecular weight phosphatase family protein
compare
MMP
_RS06540
+0.5
1.1
3-methyl-2-oxobutanoate dehydrogenase subunit VorB
compare
MMP
_RS04985
+0.5
1.0
DUF2180 family protein
compare
MMP
_RS01605
+0.5
1.6
hypothetical protein
compare
MMP
_RS04445
+0.5
1.6
P-II family nitrogen regulator
compare
MMP
_RS00400
+0.5
1.4
tributyrin esterase
compare
MMP
_RS01850
+0.5
2.2
phosphate ABC transporter substrate-binding protein
compare
MMP
_RS04285
+0.4
1.2
Ni/Fe hydrogenase subunit alpha
compare
MMP
_RS07900
+0.4
0.7
YeeE/YedE family protein
compare
MMP
_RS06660
+0.4
1.5
glycosyltransferase family 4 protein
compare
MMP
_RS08620
+0.4
1.9
flagellar accessory protein FlaH
compare
MMP
_RS00705
+0.4
1.1
hypothetical protein
compare
MMP
_RS04800
+0.4
1.5
chemotaxis protein CheW
compare
MMP
_RS06710
+0.4
1.0
selenium-binding protein
compare
MMP
_RS01675
+0.4
0.7
hypothetical protein
compare
MMP
_RS06015
+0.4
1.4
flavodoxin family protein
compare
MMP
_RS01785
+0.4
1.5
hypothetical protein
compare
MMP
_RS03775
+0.4
0.9
4Fe-4S dicluster domain-containing protein
compare
MMP
_RS06480
+0.4
1.5
ABC transporter substrate-binding protein
compare
MMP
_RS07555
+0.4
0.3
monovalent cation/H+ antiporter subunit E
compare
MMP
_RS08280
+0.4
1.1
proteasome assembly chaperone family protein
compare
MMP
_RS06175
+0.4
2.6
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS03910
+0.4
0.9
hypothetical protein
compare
MMP
_RS08700
+0.4
1.8
hypothetical protein
compare
MMP
_RS05780
+0.4
1.7
multidrug resistance efflux transporter family protein
compare
MMP
_RS03960
+0.4
0.3
hypothetical protein
compare
MMP
_RS03840
+0.4
1.0
hypothetical protein
compare
MMP
_RS01630
+0.4
1.9
N-glycosylase/DNA lyase
compare
MMP
_RS03655
+0.4
1.5
DUF1894 domain-containing protein
compare
MMP
_RS02870
+0.4
1.6
hypothetical protein
compare
MMP
_RS06590
+0.4
0.9
GNAT family N-acetyltransferase
compare
MMP
_RS07590
+0.4
2.4
hypothetical protein
compare
MMP
_RS08085
+0.4
1.7
hypothetical protein
compare
MMP
_RS08430
+0.4
1.0
HAD family hydrolase
compare
MMP
_RS06000
+0.4
0.8
divalent-cation tolerance protein CutA
compare
MMP
_RS01960
+0.4
0.2
hypothetical protein
compare
MMP
_RS00565
+0.4
1.4
CBS domain-containing protein
compare
MMP
_RS05940
+0.4
1.2
corrinoid protein
compare
MMP
_RS00090
+0.4
1.4
CoA-binding protein
compare
MMP
_RS03895
+0.4
0.8
hypothetical protein
compare
MMP
_RS06155
+0.4
0.7
DUF4186 domain-containing protein
compare
MMP
_RS07855
+0.4
1.8
class I SAM-dependent methyltransferase
compare
MMP
_RS08275
+0.3
2.1
hypothetical protein
compare
MMP
_RS01490
+0.3
1.3
tetratricopeptide repeat protein
compare
MMP
_RS08500
+0.3
1.0
pyridoxal 5'-phosphate synthase glutaminase subunit PdxT
compare
MMP
_RS05535
+0.3
0.7
hypothetical protein
compare
MMP
_RS08640
+0.3
1.8
TIM barrel protein
compare
MMP
_RS01965
+0.3
0.9
DUF1616 domain-containing protein
compare
MMP
_RS06585
+0.3
0.6
DMT family protein
compare
MMP
_RS08405
+0.3
1.6
MFS transporter
compare
MMP
_RS02530
+0.3
1.8
type II toxin-antitoxin system mRNA interferase toxin RelE/StbE family
compare
MMP
_RS01445
+0.3
1.0
hypothetical protein
compare
MMP
_RS06150
+0.3
1.6
hypothetical protein
compare
MMP
_RS01575
+0.3
1.1
aldolase
compare
MMP
_RS05085
+0.3
1.1
AAA family ATPase
compare
MMP
_RS08230
+0.3
1.2
50S ribosomal protein L11 methyltransferase
compare
MMP
_RS04165
+0.3
1.1
TetR/AcrR family transcriptional regulator
compare
MMP
_RS00155
+0.3
1.0
heavy metal-binding domain-containing protein
compare
MMP
_RS06375
+0.3
1.2
ATP-dependent sacrificial sulfur transferase LarE
compare
MMP
_RS08670
+0.3
1.3
metallophosphoesterase
compare
MMP
_RS01745
+0.3
1.0
AMP phosphorylase
compare
MMP
_RS06860
+0.3
0.6
4Fe-4S binding protein
compare
MMP
_RS05035
+0.3
1.3
hypothetical protein
compare
MMP
_RS08490
+0.3
1.9
hypothetical protein
compare
MMP
_RS00660
+0.3
1.7
alkaline phosphatase family protein
compare
MMP
_RS05980
+0.3
1.3
ferritin
compare
MMP
_RS03575
+0.3
1.3
ECF transporter S component
compare
MMP
_RS07125
+0.3
0.9
coenzyme F420-reducing hydrogenase FrhD protein
compare
MMP
_RS06875
+0.3
1.3
FAD-dependent oxidoreductase
compare
MMP
_RS02370
+0.3
0.7
NifB/NifX family molybdenum-iron cluster-binding protein
compare
MMP
_RS02320
+0.3
1.4
glutamate-cysteine ligase family protein
compare
MMP
_RS06970
+0.3
1.3
ribosomal protein S18-alanine N-acetyltransferase
compare
MMP
_RS07345
+0.3
1.4
glycine synthesis protein GlyXL
(from data)
compare
MMP
_RS03890
+0.3
1.1
DUF2540 domain-containing protein
compare
MMP
_RS08580
+0.3
0.5
flagellin
compare
MMP
_RS02915
+0.3
1.2
amino acid ABC transporter permease
compare
MMP
_RS08980
+0.3
1.0
hypothetical protein
compare
MMP
_RS08215
+0.3
0.8
DUF483 domain-containing protein
compare
MMP
_RS00545
+0.3
1.3
XRE family transcriptional regulator
compare
MMP
_RS06920
+0.3
1.4
AAA family ATPase
compare
MMP
_RS07775
+0.3
1.4
alanine dehydrogenase
compare
MMP
_RS03680
+0.3
1.1
hypothetical protein
compare
MMP
_RS01370
+0.3
1.8
acetate--CoA ligase family protein
compare
MMP
_RS07185
+0.3
1.6
pyridoxal phosphate-dependent aminotransferase
compare
MMP
_RS05665
+0.3
0.8
phosphate ABC transporter permease subunit PstC
compare
MMP
_RS07145
+0.3
1.1
AmmeMemoRadiSam system protein B
compare
MMP
_RS05895
+0.3
1.3
metallophosphoesterase
compare
MMP
_RS06745
+0.3
0.6
DUF2119 domain-containing protein
compare
MMP
_RS03150
+0.3
1.7
phosphoglycerate mutase
compare
MMP
_RS01515
+0.3
1.2
PINc/VapC family ATPase
compare
MMP
_RS02735
+0.3
0.5
MBL fold metallo-hydrolase
compare
MMP
_RS05020
+0.2
0.8
hypothetical protein
compare
MMP
_RS03885
+0.2
1.1
tyrosine-type recombinase/integrase
compare
MMP
_RS00480
+0.2
1.1
hypothetical protein
compare
MMP
_RS03070
+0.2
0.7
AzlD domain-containing protein
compare
MMP
_RS02940
+0.2
0.8
TatD family hydrolase
compare
MMP
_RS08285
+0.2
1.2
serine/threonine protein kinase
compare
MMP
_RS06445
+0.2
0.6
DUF89 domain-containing protein
compare
MMP
_RS01470
+0.2
0.9
ATP-binding cassette domain-containing protein
compare
MMP
_RS02620
+0.2
1.4
DEAD/DEAH box helicase
compare
MMP
_RS07820
+0.2
0.8
UPF0104 family protein
compare
MMP
_RS03965
+0.2
0.6
hypothetical protein
compare
MMP
_RS05505
+0.2
1.1
class IV adenylate cyclase
compare
MMP
_RS04520
+0.2
0.5
nucleoside deaminase
compare
MMP
_RS03520
+0.2
0.5
YwbE family protein
compare
MMP
_RS08775
+0.2
0.9
methanogenesis marker 9 domain-containing protein
compare
MMP
_RS05935
+0.2
1.2
uroporphyrinogen decarboxylase family protein
compare
MMP
_RS06545
+0.2
0.7
ferredoxin family protein
compare
MMP
_RS05975
+0.2
0.4
hypothetical protein
compare
MMP
_RS06185
+0.2
1.0
thermonuclease family protein
compare
MMP
_RS06675
+0.2
1.0
ADP-specific phosphofructokinase
compare
MMP
_RS02025
+0.2
1.6
DNA-directed DNA polymerase
compare
MMP
_RS00235
+0.2
1.4
HDIG domain-containing protein
compare
MMP
_RS00710
+0.2
0.7
hypothetical protein
compare
MMP
_RS01455
+0.2
0.9
nickel pincer cofactor biosynthesis protein LarC
compare
MMP
_RS00035
+0.2
1.2
DUF2098 family protein
compare
MMP
_RS06045
+0.2
1.2
DNA polymerase
compare
MMP
_RS05695
+0.2
1.2
phospholipase D-like domain-containing protein
compare
MMP
_RS06975
+0.2
0.4
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMP
_RS00150
+0.2
0.7
AAA family ATPase
compare
MMP
_RS00910
+0.2
1.0
2-phosphosulfolactate phosphatase
compare
MMP
_RS03570
+0.2
1.2
uracil-xanthine permease family protein
compare
MMP
_RS05985
+0.2
0.7
hypothetical protein
compare
MMP
_RS08705
+0.2
0.8
sulfopyruvate decarboxylase subunit beta
compare
MMP
_RS05275
+0.2
1.1
AI-2E family transporter
compare
MMP
_RS00770
+0.2
0.8
hypothetical protein
compare
MMP
_RS03875
+0.2
0.8
hypothetical protein
compare
MMP
_RS02795
+0.2
1.3
sulfate permease
compare
MMP
_RS02810
+0.2
0.9
hypothetical protein
compare
MMP
_RS07640
+0.2
0.7
mechanosensitive ion channel family protein
compare
MMP
_RS07120
+0.2
1.1
coenzyme F420 hydrogenase subunit alpha
compare
MMP
_RS05995
+0.2
1.1
FprA family A-type flavoprotein
compare
MMP
_RS01660
+0.2
0.5
hypothetical protein
compare
MMP
_RS08630
+0.2
0.7
archaellar assembly protein FlaJ
compare
MMP
_RS02705
+0.2
0.9
formylmethanofuran dehydrogenase subunit B
compare
MMP
_RS06060
+0.2
0.7
hypothetical protein
compare
MMP
_RS07805
+0.2
0.9
ABC transporter permease
compare
MMP
_RS02625
+0.2
1.1
ribonuclease H-like domain-containing protein
compare
MMP
_RS00185
+0.2
1.4
potassium channel protein
compare
MMP
_RS08480
+0.2
1.3
molybdate ABC transporter substrate-binding protein
compare
MMP
_RS02425
+0.2
0.6
hypothetical protein
compare
MMP
_RS04415
+0.2
0.8
peptide-methionine (S)-S-oxide reductase MsrA
compare
MMP
_RS01775
+0.2
0.4
TIGR00297 family protein
compare
MMP
_RS07530
+0.2
0.8
4Fe-4S binding protein
compare
MMP
_RS04700
+0.2
1.2
hypothetical protein
compare
MMP
_RS00390
+0.2
0.9
ammonium transporter
compare
MMP
_RS02910
+0.2
0.8
ABC transporter substrate-binding protein
compare
MMP
_RS08130
+0.2
1.0
IGHMBP2 family helicase
compare
MMP
_RS04305
+0.2
0.4
hypothetical protein
compare
MMP
_RS01065
+0.2
1.2
alpha/beta hydrolase
compare
MMP
_RS05660
+0.2
0.9
phosphate ABC transporter substrate-binding protein
compare
MMP
_RS03870
+0.2
0.6
purine NTPase
compare
MMP
_RS01640
+0.2
0.8
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis S2 in rich t1 experiments