Experiment set5IT009 for Methanococcus maripaludis S2

200 most detrimental genes:

gene	name	fitness	t score	description
MMP_RS03300		+1.7	2.8	TOBE domain-containing protein
MMP_RS02470		+1.2	1.2	helix-turn-helix transcriptional regulator
MMP_RS05835		+1.1	1.5	secondary thiamine-phosphate synthase enzyme YjbQ
MMP_RS04055		+1.1	2.7	hypothetical protein
MMP_RS08415		+1.0	2.6	radical SAM protein
MMP_RS08315		+0.9	2.7	S-methyl-5-thioribose-1-phosphate isomerase
MMP_RS05365		+0.9	1.7	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH
MMP_RS08280		+0.9	2.2	proteasome assembly chaperone family protein
MMP_RS02815		+0.8	2.8	hypothetical protein
MMP_RS06860		+0.8	2.4	4Fe-4S binding protein
MMP_RS03350		+0.8	2.6	winged helix-turn-helix domain-containing protein
MMP_RS08310		+0.8	2.1	TMEM165/GDT1 family protein
MMP_RS00825		+0.8	1.9	fumarylacetoacetate hydrolase family protein
MMP_RS07890		+0.8	2.7	OB-fold nucleic acid binding domain-containing protein
MMP_RS08615		+0.7	1.8	flagellar protein G
MMP_RS06140		+0.7	2.0	radical SAM protein
MMP_RS07805		+0.7	3.2	ABC transporter permease
MMP_RS06335		+0.7	2.9	HAD family hydrolase
MMP_RS01435		+0.7	3.9	DMT family transporter
MMP_RS06905		+0.7	1.8	hypothetical protein
MMP_RS08670		+0.6	4.1	metallophosphoesterase
MMP_RS00565		+0.6	2.5	CBS domain-containing protein
MMP_RS04035		+0.6	1.3	hypothetical protein
MMP_RS01120		+0.6	2.6	permease
MMP_RS09050		+0.6	1.3	CAP domain-containing protein
MMP_RS04520		+0.6	1.8	nucleoside deaminase
MMP_RS08995		+0.6	1.1	hypothetical protein
MMP_RS08130		+0.6	3.6	IGHMBP2 family helicase
MMP_RS01570		+0.6	1.2	hypothetical protein
MMP_RS08580		+0.6	1.4	flagellin
MMP_RS02290		+0.6	2.4	MBL fold metallo-hydrolase
MMP_RS06155		+0.5	1.0	DUF4186 domain-containing protein
MMP_RS06055		+0.5	2.2	peroxiredoxin
MMP_RS06290		+0.5	2.1	DNA repair and recombination protein RadA
MMP_RS05820		+0.5	2.1	RNA-binding transcriptional accessory protein
MMP_RS02495		+0.5	1.9	hypothetical protein
MMP_RS04015		+0.5	1.2	hypothetical protein
MMP_RS01775		+0.5	1.3	TIGR00297 family protein
MMP_RS02475		+0.5	1.8	hypothetical protein
MMP_RS00905		+0.5	1.2	phenylacetate--CoA ligase
MMP_RS00185		+0.5	3.4	potassium channel protein
MMP_RS05795		+0.5	1.7	redox-regulated ATPase YchF
MMP_RS06445		+0.5	2.5	DUF89 domain-containing protein
MMP_RS08175		+0.5	1.5	7-cyano-7-deazaguanine synthase
MMP_RS07925		+0.5	1.4	haloacid dehalogenase
MMP_RS06460		+0.5	1.7	pyrimidine dimer DNA glycosylase/endonuclease V
MMP_RS08850		+0.5	3.6	hypothetical protein
MMP_RS03535		+0.5	1.1	helix-turn-helix transcriptional regulator
MMP_RS05660		+0.5	2.3	phosphate ABC transporter substrate-binding protein
MMP_RS08455		+0.5	1.2	multiprotein bridging factor aMBF1
MMP_RS01540		+0.5	1.6	DUF504 domain-containing protein
MMP_RS02455		+0.5	2.0	hypothetical protein
MMP_RS08285		+0.5	3.3	serine/threonine protein kinase
MMP_RS02100		+0.5	1.7	metallophosphoesterase
MMP_RS03150		+0.5	2.1	phosphoglycerate mutase
MMP_RS08395		+0.4	1.8	DsrE family protein
MMP_RS00450		+0.4	0.4	4Fe-4S binding protein
MMP_RS08235		+0.4	1.3	hypothetical protein
MMP_RS08325		+0.4	2.9	hypothetical protein
MMP_RS07590		+0.4	3.1	hypothetical protein
MMP_RS07345		+0.4	2.3	glycine synthesis protein GlyXL (from data)
MMP_RS08980		+0.4	1.4	hypothetical protein
MMP_RS07775		+0.4	1.1	alanine dehydrogenase
MMP_RS02770		+0.4	1.2	hypothetical protein
MMP_RS01605		+0.4	1.5	hypothetical protein
MMP_RS05695		+0.4	1.8	phospholipase D-like domain-containing protein
MMP_RS00395		+0.4	0.9	MGMT family protein
MMP_RS06520		+0.4	2.0	DUF1786 domain-containing protein
MMP_RS06920		+0.4	2.6	AAA family ATPase
MMP_RS02745		+0.4	1.4	hypothetical protein
MMP_RS06910		+0.4	2.1	RlmF-related methyltransferase
MMP_RS08205		+0.4	2.0	stage II sporulation protein M
MMP_RS01525		+0.4	0.9	nucleoside-diphosphate kinase
MMP_RS01420		+0.4	0.8	hypothetical protein
MMP_RS08385		+0.4	1.4	ABC transporter substrate-binding protein
MMP_RS06530		+0.4	1.3	bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
MMP_RS04635		+0.4	1.6	GNAT family N-acetyltransferase
MMP_RS06325		+0.4	0.8	hypothetical protein
MMP_RS08665		+0.4	3.2	hypothetical protein
MMP_RS00385		+0.4	1.9	P-II family nitrogen regulator
MMP_RS07335		+0.4	1.6	tRNA (cytidine(56)-2'-O)-methyltransferase
MMP_RS08410		+0.4	1.4	DUF169 domain-containing protein
MMP_RS03870		+0.4	1.9	purine NTPase
MMP_RS08930		+0.4	0.8	hypothetical protein
MMP_RS01630		+0.4	1.5	N-glycosylase/DNA lyase
MMP_RS01470		+0.4	1.7	ATP-binding cassette domain-containing protein
MMP_RS06280		+0.4	2.2	alpha-glucan family phosphorylase
MMP_RS06660		+0.4	2.1	glycosyltransferase family 4 protein
MMP_RS00400		+0.4	1.4	tributyrin esterase
MMP_RS08480		+0.4	1.9	molybdate ABC transporter substrate-binding protein
MMP_RS00655		+0.4	1.4	hypothetical protein
MMP_RS08080		+0.4	2.2	YchF/TatD family DNA exonuclease
MMP_RS02595		+0.4	0.7	putative zinc-binding protein
MMP_RS02605		+0.4	0.5	MotA/TolQ/ExbB proton channel family protein
MMP_RS08630		+0.4	1.7	archaellar assembly protein FlaJ
MMP_RS08705		+0.4	1.6	sulfopyruvate decarboxylase subunit beta
MMP_RS08640		+0.4	1.8	TIM barrel protein
MMP_RS01185		+0.4	1.5	hypothetical protein
MMP_RS07415		+0.4	2.0	molybdopterin-guanine dinucleotide biosynthesis protein MobB
MMP_RS06560		+0.4	1.6	hypothetical protein
MMP_RS03875		+0.4	1.0	hypothetical protein
MMP_RS05825		+0.4	1.7	peptidyl-prolyl cis-trans isomerase
MMP_RS07150		+0.4	1.6	MTH895/ArsE family thioredoxin-like protein
MMP_RS07850		+0.3	1.3	prephenate dehydratase
MMP_RS00535		+0.3	1.1	TIGR00375 family protein
MMP_RS02170		+0.3	1.4	CBS domain-containing protein
MMP_RS05995		+0.3	1.7	FprA family A-type flavoprotein
MMP_RS06300		+0.3	1.8	ABC transporter substrate-binding protein
MMP_RS00950		+0.3	1.4	site-2 protease family protein
MMP_RS00660		+0.3	2.0	alkaline phosphatase family protein
MMP_RS05790		+0.3	1.6	HDIG domain-containing protein
MMP_RS08265		+0.3	0.9	rubrerythrin
MMP_RS06185		+0.3	1.7	thermonuclease family protein
MMP_RS07140		+0.3	2.2	TIGR00341 family protein
MMP_RS04985		+0.3	0.9	DUF2180 family protein
MMP_RS01090		+0.3	1.8	ABC transporter substrate-binding protein
MMP_RS00910		+0.3	1.6	2-phosphosulfolactate phosphatase
MMP_RS00285		+0.3	1.7	TIGR04013 family B12-binding domain/radical SAM domain-containing protein
MMP_RS08380		+0.3	0.7	phosphatase PAP2 family protein
MMP_RS08775		+0.3	1.2	methanogenesis marker 9 domain-containing protein
MMP_RS00125		+0.3	0.7	DUF2798 domain-containing protein
MMP_RS08405		+0.3	2.0	MFS transporter
MMP_RS01215		+0.3	1.6	sodium/proline symporter PutP
MMP_RS01140		+0.3	0.6	molybdate ABC transporter permease subunit
MMP_RS06590		+0.3	0.8	GNAT family N-acetyltransferase
MMP_RS07550		+0.3	1.6	L-serine ammonia-lyase iron-sulfur-dependent subunit alpha
MMP_RS02315		+0.3	1.6	RimK family alpha-L-glutamate ligase
MMP_RS07130		+0.3	2.0	coenzyme F420 hydrogenase subunit gamma
MMP_RS03785		+0.3	0.9	cupin domain-containing protein
MMP_RS06065		+0.3	2.6	iron ABC transporter substrate-binding protein
MMP_RS03220		+0.3	0.5	RNA 2' 3'-cyclic phosphodiesterase
MMP_RS09030		+0.3	1.3	hypothetical protein
MMP_RS08535		+0.3	1.2	bis-aminopropyl spermidine synthase family protein
MMP_RS01210		+0.3	1.4	sodium:solute symporter
MMP_RS01430		+0.3	1.9	mechanosensitive ion channel family protein
MMP_RS07185		+0.3	1.9	pyridoxal phosphate-dependent aminotransferase
MMP_RS07770		+0.3	1.5	alanine racemase
MMP_RS04610		+0.3	1.2	Dabb family protein
MMP_RS02260		+0.3	1.7	lactate utilization protein
MMP_RS08275		+0.3	2.2	hypothetical protein
MMP_RS08390		+0.3	1.9	DUF5400 domain-containing protein
MMP_RS02325		+0.3	1.7	epoxyqueuosine reductase
MMP_RS04960		+0.3	1.8	cytochrome c biogenesis CcdA family protein
MMP_RS06535		+0.3	0.9	2-oxoacid:acceptor oxidoreductase family protein
MMP_RS06875		+0.3	1.7	FAD-dependent oxidoreductase
MMP_RS08595		+0.3	0.4	flagellar protein C
MMP_RS01580		+0.3	1.3	PQQ-binding-like beta-propeller repeat protein
MMP_RS04190		+0.3	1.2	hypothetical protein
MMP_RS01070		+0.3	2.0	hypothetical protein
MMP_RS06175		+0.3	1.3	winged helix-turn-helix transcriptional regulator
MMP_RS06610		+0.3	0.9	DUF2334 domain-containing protein
MMP_RS01685		+0.3	0.8	indolepyruvate oxidoreductase subunit beta
MMP_RS07885		+0.3	0.9	tripartite tricarboxylate transporter permease
MMP_RS06500		+0.3	1.3	ATP-binding protein
MMP_RS03770		+0.3	1.0	hydroxylamine reductase
MMP_RS04675		+0.3	1.7	selenouridine synthase SelU-like subunit
MMP_RS08225		+0.3	1.4	RimK family alpha-L-glutamate ligase
MMP_RS02740		+0.3	1.1	hypothetical protein
MMP_RS07145		+0.3	1.3	AmmeMemoRadiSam system protein B
MMP_RS03340		+0.3	0.3	ABC transporter ATP-binding protein
MMP_RS03965		+0.3	0.8	hypothetical protein
MMP_RS02365		+0.3	1.6	nitrogen fixation
MMP_RS02045		+0.3	0.6	tRNA-Met
MMP_RS08230		+0.3	1.3	50S ribosomal protein L11 methyltransferase
MMP_RS05940		+0.3	1.0	corrinoid protein
MMP_RS07125		+0.3	0.9	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS04275		+0.3	1.2	hydrogenase iron-sulfur subunit
MMP_RS06585		+0.3	0.6	DMT family protein
MMP_RS05900		+0.3	1.2	tetratricopeptide repeat protein
MMP_RS08845		+0.3	1.5	archaellum operon transcriptional activator EarA family protein
MMP_RS06095		+0.3	1.1	ABC transporter ATP-binding protein
MMP_RS00540		+0.3	1.6	PLP-dependent aminotransferase family protein
MMP_RS05715		+0.3	0.8	hypothetical protein
MMP_RS01110		+0.3	0.8	FmdE family protein
MMP_RS02085		+0.3	1.5	inosine/xanthosine triphosphatase
MMP_RS04980		+0.3	1.9	DUF2193 domain-containing protein
MMP_RS00040		+0.3	1.0	TIGR03576 family pyridoxal phosphate-dependent enzyme
MMP_RS07115		+0.3	1.5	MBL fold metallo-hydrolase
MMP_RS04840		+0.3	1.1	response regulator
MMP_RS07855		+0.3	1.5	class I SAM-dependent methyltransferase
MMP_RS01850		+0.3	1.6	phosphate ABC transporter substrate-binding protein
MMP_RS02360		+0.2	0.8	hypothetical protein
MMP_RS00665		+0.2	0.8	hypothetical protein
MMP_RS03990		+0.2	1.4	recombinase family protein
MMP_RS04175		+0.2	1.3	permease
MMP_RS03465		+0.2	0.4	adenine phosphoribosyltransferase
MMP_RS08625		+0.2	1.5	type II/IV secretion system ATPase subunit
MMP_RS07715		+0.2	1.7	YfcE family phosphodiesterase
MMP_RS04265		+0.2	0.8	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS07800		+0.2	1.2	ATP-binding cassette domain-containing protein
MMP_RS08245		+0.2	1.3	DUF4013 domain-containing protein
MMP_RS01370		+0.2	1.6	acetate--CoA ligase family protein
MMP_RS02760		+0.2	1.4	COG1361 S-layer family protein
MMP_RS07560		+0.2	0.8	prefoldin subunit alpha
MMP_RS06060		+0.2	0.9	hypothetical protein
MMP_RS05680		+0.2	1.2	phosphate signaling complex protein PhoU
MMP_RS06275		+0.2	1.4	ATP-dependent DNA helicase
MMP_RS01105		+0.2	1.0	hypothetical protein
MMP_RS05275		+0.2	1.5	AI-2E family transporter
MMP_RS01460		+0.2	0.6	hypothetical protein

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in rich t1 experiments