Experiment set5IT009 for Klebsiella michiganensis M5al

Compare to:

m-Inositol carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS18925 -6.7 -6.6 histidinol dehydrogenase compare
BWI76_RS18920 -6.6 -4.6 ATP phosphoribosyltransferase compare
BWI76_RS04465 -6.5 -4.5 carbamoyl-phosphate synthase small subunit compare
BWI76_RS04160 -6.5 -7.4 phosphoserine phosphatase compare
BWI76_RS18935 -6.4 -8.8 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS18950 -6.4 -6.2 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS05835 -6.2 -4.2 gamma-glutamyl-phosphate reductase compare
BWI76_RS02995 -6.0 -8.3 aspartate carbamoyltransferase compare
BWI76_RS09760 -6.0 -7.2 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS18930 -6.0 -4.9 histidinol-phosphate transaminase compare
BWI76_RS18940 -6.0 -7.1 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS00785 -5.9 -4.1 cystathionine gamma-synthase compare
BWI76_RS22805 -5.9 -9.8 GTP diphosphokinase compare
BWI76_RS04675 -5.8 -7.9 3-isopropylmalate dehydrogenase compare
BWI76_RS04255 -5.8 -9.6 threonine synthase compare
BWI76_RS23920 -5.7 -5.6 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS00805 -5.6 -6.1 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS09755 -5.6 -8.6 phosphoserine transaminase compare
BWI76_RS01210 -5.6 -3.5 tyrosine recombinase XerC compare
BWI76_RS18955 -5.6 -6.6 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS00850 -5.6 -11.5 acetylglutamate kinase compare
BWI76_RS04470 -5.5 -10.6 carbamoyl phosphate synthase large subunit compare
BWI76_RS11850 -5.5 -8.3 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS04670 -5.4 -10.4 3-isopropylmalate dehydratase large subunit compare
BWI76_RS26085 -5.4 -3.7 3-dehydroquinate synthase compare
BWI76_RS04250 -5.4 -9.0 homoserine kinase compare
BWI76_RS20355 -5.4 -3.7 colicin V production protein compare
BWI76_RS17720 -5.3 -2.3 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS00980 -5.2 -11.1 PLP-dependent threonine dehydratase compare
BWI76_RS20350 -5.2 -9.0 amidophosphoribosyltransferase compare
BWI76_RS00990 -5.1 -9.1 ketol-acid reductoisomerase compare
BWI76_RS05840 -5.1 -6.9 glutamate 5-kinase compare
BWI76_RS23360 -5.0 -4.9 diaminopimelate decarboxylase compare
BWI76_RS22755 -4.9 -9.3 phosphoadenosine phosphosulfate reductase compare
BWI76_RS24285 -4.9 -8.7 cystathionine beta-lyase compare
BWI76_RS00845 -4.8 -9.9 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS01655 -4.8 -7.8 homoserine O-succinyltransferase compare
BWI76_RS04665 -4.8 -19.7 3-isopropylmalate dehydratase small subunit compare
BWI76_RS21475 -4.7 -5.1 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS01615 -4.7 -12.5 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS25115 -4.7 -7.9 argininosuccinate synthase compare
BWI76_RS21265 -4.6 -15.0 phosphoribosylformylglycinamidine synthase compare
BWI76_RS04645 -4.6 -6.5 3-dehydroquinase compare
BWI76_RS11965 -4.6 -4.4 orotidine-5'-phosphate decarboxylase compare
BWI76_RS04685 -4.6 -11.8 putative leucine operon leader peptide compare
BWI76_RS00855 -4.5 -9.6 argininosuccinate lyase compare
BWI76_RS03010 -4.5 -11.1 ornithine carbamoyltransferase compare
BWI76_RS20965 -4.4 -5.4 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS00975 -4.4 -9.7 dihydroxy-acid dehydratase compare
BWI76_RS09910 -4.4 -18.4 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS21465 -4.3 -4.8 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS04240 -4.2 -2.0 thr operon leader peptide compare
BWI76_RS04245 -4.1 -13.5 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS11845 -4.1 -2.7 tryptophan synthase subunit beta compare
BWI76_RS04680 -4.0 -10.7 2-isopropylmalate synthase compare
BWI76_RS05015 -4.0 -4.4 transcriptional regulator compare
BWI76_RS23240 -4.0 -2.7 exonuclease V subunit gamma compare
BWI76_RS07070 -3.9 -6.3 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS00985 -3.9 -7.9 transcriptional regulator IlvY compare
BWI76_RS20895 -3.9 -5.4 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS23265 -3.9 -4.0 hypothetical protein compare
BWI76_RS09660 -3.8 -2.6 DNA translocase FtsK compare
BWI76_RS11855 -3.8 -9.0 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS23365 -3.8 -8.4 LysR family transcriptional regulator compare
BWI76_RS20435 -3.7 -2.3 chorismate synthase compare
BWI76_RS11860 -3.7 -6.6 anthranilate synthase component I compare
BWI76_RS27385 -3.7 -7.1 orotate phosphoribosyltransferase compare
BWI76_RS07065 -3.7 -9.1 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS11840 -3.7 -3.7 tryptophan synthase subunit alpha compare
BWI76_RS02815 -3.7 -3.2 fructose-bisphosphatase class I compare
BWI76_RS23220 -3.7 -8.1 amino-acid N-acetyltransferase compare
BWI76_RS27390 -3.6 -4.0 ribonuclease PH compare
BWI76_RS26455 -3.4 -3.9 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS22765 -3.4 -14.2 sulfite reductase subunit alpha compare
BWI76_RS00400 -3.4 -2.3 glutamine synthetase compare
BWI76_RS01610 -3.3 -6.7 phosphoribosylamine--glycine ligase compare
BWI76_RS23480 -3.3 -14.6 EAL domain-containing protein compare
BWI76_RS00965 -3.2 -2.0 acetolactate synthase 2 small subunit compare
BWI76_RS00835 -3.2 -10.2 phosphoenolpyruvate carboxylase compare
BWI76_RS10990 -3.2 -3.6 dihydroorotase compare
BWI76_RS22760 -3.2 -7.2 sulfite reductase subunit beta compare
BWI76_RS01185 -3.2 -2.2 adenylate cyclase compare
BWI76_RS23230 -3.0 -2.9 exodeoxyribonuclease V subunit beta compare
BWI76_RS02735 -3.0 -6.0 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS03095 -2.9 -5.6 Inositol 2-dehydrogenase (EC 1.1.1.18) (from data) conserved
BWI76_RS27440 -2.7 -4.8 DNA helicase RecG compare
BWI76_RS09645 -2.7 -2.0 thioredoxin-disulfide reductase compare
BWI76_RS20970 -2.7 -2.3 phosphoribosylglycinamide formyltransferase compare
BWI76_RS25335 -2.6 -3.2 stringent starvation protein A compare
BWI76_RS01200 -2.6 -3.0 diaminopimelate epimerase compare
BWI76_RS22690 -2.5 -4.5 adenylyl-sulfate kinase compare
BWI76_RS03075 -2.5 -11.5 5-deoxy-D-glucuronate isomerase (EC 5.3.1.30) (from data) conserved
BWI76_RS05200 -2.5 -3.0 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS00345 -2.5 -4.0 protein disulfide oxidoreductase DsbA compare
BWI76_RS15825 -2.5 -1.7 hypothetical protein compare
BWI76_RS27430 -2.5 -2.1 (p)ppGpp synthetase compare
BWI76_RS20650 -2.3 -2.2 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS03100 -2.3 -3.5 protein iolH compare
BWI76_RS09640 -2.2 -4.1 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD compare
BWI76_RS26460 -2.2 -3.4 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS08385 -2.1 -3.1 citrate (Si)-synthase compare
BWI76_RS26395 -2.1 -3.7 cell division protein FtsE compare
BWI76_RS26890 -2.0 -1.8 hypothetical protein compare
BWI76_RS20440 -2.0 -2.5 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS26000 -2.0 -8.1 aspartate aminotransferase family protein compare
BWI76_RS03105 -2.0 -1.4 myo-inosose-2 dehydratase compare
BWI76_RS03085 -2.0 -8.6 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92); possible 5-dehydro-2-deoxyphosphogluconate aldolase DUF2090 (EC 4.1.2.29) (from data) conserved
BWI76_RS00180 -1.9 -2.6 F0F1 ATP synthase subunit epsilon compare
BWI76_RS25320 -1.9 -9.1 glutamate synthase compare
BWI76_RS26390 -1.9 -5.3 cell division protein FtsX compare
BWI76_RS03090 -1.9 -8.2 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) (from data) conserved
BWI76_RS26075 -1.9 -4.2 DNA adenine methylase compare
BWI76_RS26055 -1.8 -4.7 siroheme synthase compare
BWI76_RS25645 -1.8 -6.2 shikimate dehydrogenase compare
BWI76_RS08530 -1.8 -2.3 protein TolA compare
BWI76_RS20995 -1.8 -4.1 RNA degradosome polyphosphate kinase compare
BWI76_RS02530 -1.7 -2.8 tRNA dimethylallyltransferase compare
BWI76_RS00390 -1.7 -4.1 two-component system sensor histidine kinase NtrB compare
BWI76_RS21310 -1.7 -1.4 DNA repair protein RecO compare
BWI76_RS25315 -1.7 -8.4 glutamate synthase large subunit compare
BWI76_RS20640 -1.7 -3.9 cysteine synthase A compare
BWI76_RS25065 -1.7 -3.4 polyribonucleotide nucleotidyltransferase compare
BWI76_RS08520 -1.7 -1.5 colicin transporter TolQ compare
BWI76_RS25425 -1.6 -2.1 arginine repressor compare
BWI76_RS26685 -1.6 -5.8 glutathione-disulfide reductase compare
BWI76_RS09970 -1.6 -2.6 porin OmpA compare
BWI76_RS21140 -1.6 -2.0 molecular chaperone HscA compare
BWI76_RS25600 -1.6 -1.3 tRNA-Thr compare
BWI76_RS02410 -1.5 -1.9 EF-P beta-lysylation protein EpmB compare
BWI76_RS27875 -1.5 -1.6 membrane protein compare
BWI76_RS16275 -1.5 -2.7 fumarate hydratase FumA compare
BWI76_RS00960 -1.5 -6.5 acetolactate synthase 2 catalytic subunit compare
BWI76_RS17980 -1.5 -5.7 RNA chaperone ProQ compare
BWI76_RS15835 -1.5 -1.0 hypothetical protein compare
BWI76_RS25000 -1.4 -1.4 malonate decarboxylase acyl carrier protein compare
BWI76_RS01800 -1.4 -3.1 glucose-6-phosphate isomerase compare
BWI76_RS01885 -1.4 -1.6 CsbD family protein compare
BWI76_RS04530 -1.4 -2.1 peptidylprolyl isomerase SurA compare
BWI76_RS19850 -1.4 -3.2 tRNA-Pro compare
BWI76_RS19690 -1.4 -1.5 LysR family transcriptional regulator compare
BWI76_RS15060 -1.4 -3.0 MarR family transcriptional regulator compare
BWI76_RS01775 -1.4 -1.4 hypothetical protein compare
BWI76_RS03070 -1.4 -4.4 Methylmalonate-semialdehyde dehydrogenase [inositol] (EC 1.2.1.27) (from data) conserved
BWI76_RS08525 -1.4 -3.2 colicin transporter compare
BWI76_RS07725 -1.4 -1.5 iron-enterobactin transporter permease compare
BWI76_RS19495 -1.3 -1.5 ABC transporter, quaternary amine uptake transporter (QAT) family, ATP-binding protein compare
BWI76_RS06525 -1.3 -5.1 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS12145 -1.3 -2.0 hypothetical protein compare
BWI76_RS23885 -1.3 -2.0 2-octaprenylphenol hydroxylase compare
BWI76_RS24945 -1.3 -1.2 glutamine amidotransferase compare
BWI76_RS00970 -1.3 -3.0 branched chain amino acid aminotransferase compare
BWI76_RS15830 -1.3 -2.4 hypothetical protein compare
BWI76_RS08535 -1.3 -2.3 translocation protein TolB compare
BWI76_RS21580 -1.3 -1.1 SsrA-binding protein compare
BWI76_RS26570 -1.3 -2.9 anion permease compare
BWI76_RS11335 -1.2 -1.4 tautomerase compare
BWI76_RS01385 -1.2 -1.5 potassium transporter compare
BWI76_RS06185 -1.2 -5.9 shikimate kinase II compare
BWI76_RS09635 -1.2 -2.7 amino acid ABC transporter ATP-binding protein compare
BWI76_RS13240 -1.2 -1.5 hypothetical protein compare
BWI76_RS18730 -1.2 -3.6 LysR family transcriptional regulator conserved
BWI76_RS06475 -1.2 -1.2 protoheme IX farnesyltransferase compare
BWI76_RS21690 -1.2 -1.7 hypothetical protein compare
BWI76_RS22120 -1.2 -4.6 glutamate--cysteine ligase compare
BWI76_RS11900 -1.2 -1.3 cob(I)yrinic acid a,c-diamide adenosyltransferase compare
BWI76_RS19010 -1.2 -1.8 polysaccharide pyruvyl transferase yvff compare
BWI76_RS16515 -1.1 -1.7 LysR family transcriptional regulator compare
BWI76_RS22085 -1.1 -2.1 L-valine transporter subunit YgaH compare
BWI76_RS01275 -1.1 -4.7 LysR family transcriptional regulator compare
BWI76_RS13595 -1.1 -4.2 transcriptional regulator compare
BWI76_RS06765 -1.1 -2.0 transcriptional regulator compare
BWI76_RS18735 -1.1 -4.6 tautomerase family protein compare
BWI76_RS27815 -1.1 -7.5 acetolactate synthase catalytic subunit compare
BWI76_RS04715 -1.1 -1.2 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS12570 -1.1 -2.7 DUF1365 domain-containing protein compare
BWI76_RS17525 -1.1 -2.0 XshC-Cox1-family protein compare
BWI76_RS11565 -1.1 -6.6 DeoR family transcriptional regulator compare
BWI76_RS02180 -1.1 -1.1 hypothetical protein compare
BWI76_RS15810 -1.1 -4.3 hypothetical protein compare
BWI76_RS24075 -1.1 -2.1 glutathione synthase compare
BWI76_RS09190 -1.1 -2.5 hypothetical protein compare
BWI76_RS01325 -1.1 -2.3 twin-arginine translocase subunit TatB compare
BWI76_RS13560 -1.1 -1.0 amino acid ABC transporter substrate-binding subunit compare
BWI76_RS23915 -1.0 -2.0 5-formyltetrahydrofolate cyclo-ligase compare
BWI76_RS16805 -1.0 -1.7 basic amino acid ABC transporter substrate-binding protein compare
BWI76_RS01115 -1.0 -1.7 dTDP-4-amino-4,6-dideoxygalactose transaminase compare
BWI76_RS16315 -1.0 -1.9 SirA-like protein compare
BWI76_RS19840 -1.0 -1.2 hypothetical protein compare
BWI76_RS13820 -1.0 -1.8 hypothetical protein compare
BWI76_RS25505 -1.0 -4.7 RNase E specificity factor CsrD compare
BWI76_RS07780 -1.0 -1.3 hypothetical protein compare
BWI76_RS04510 -1.0 -1.3 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS17290 -1.0 -3.9 formyltetrahydrofolate deformylase compare
BWI76_RS00760 -1.0 -2.3 cell division protein FtsN compare
BWI76_RS19685 -0.9 -3.2 lysine transporter compare
BWI76_RS05260 -0.9 -1.4 chaperone compare
BWI76_RS24110 -0.9 -1.7 YggU family protein compare
BWI76_RS17945 -0.9 -1.2 hypothetical protein compare
BWI76_RS15955 -0.9 -4.8 transcriptional regulator compare
BWI76_RS01070 -0.9 -3.4 thiol reductase thioredoxin compare


Specific Phenotypes

For 4 genes in this experiment

For carbon source m-Inositol in Klebsiella michiganensis M5al

For carbon source m-Inositol across organisms