Experiment set5IT008 for Methanococcus maripaludis S2

Compare to:

Formate with hypochlorite 5 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS03250 -6.3 -5.9 MJ1244 family protein compare
MMP_RS00300 -4.8 -1.1 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS08300 -4.5 -2.5 metal-sulfur cluster assembly factor compare
MMP_RS02355 -4.5 -4.7 30S ribosomal protein S27ae compare
MMP_RS03315 -4.4 -2.2 ferrous iron transport protein A compare
MMP_RS02245 -4.4 -4.6 hypothetical protein compare
MMP_RS04695 -4.2 -10.9 selenide water dikinase SelD compare
MMP_RS06355 -4.1 -4.3 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS08070 -4.1 -9.7 DUF2096 domain-containing protein compare
MMP_RS01175 -3.9 -7.4 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS05920 -3.9 -1.3 50S ribosomal protein L37e compare
MMP_RS01665 -3.9 -7.2 DUF2111 domain-containing protein compare
MMP_RS06685 -3.8 -18.4 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS06700 -3.7 -21.8 hypothetical protein compare
MMP_RS01225 -3.7 -6.8 DUF5379 domain-containing protein compare
MMP_RS06680 -3.7 -17.2 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS02800 -3.7 -8.0 nucleotidyltransferase domain-containing protein compare
MMP_RS06400 -3.7 -2.9 4Fe-4S binding protein compare
MMP_RS04890 -3.6 -1.2 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS07635 -3.6 -11.4 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS03445 -3.5 -1.8 methanogenesis marker 17 protein compare
MMP_RS07575 -3.5 -6.7 RNA ligase partner protein compare
MMP_RS00120 -3.5 -7.2 LysR family transcriptional regulator compare
MMP_RS01795 -3.5 -2.4 methanogenesis marker 6 protein compare
MMP_RS06630 -3.4 -1.5 UPF0058 family protein compare
MMP_RS05925 -3.4 -5.4 small nuclear ribonucleoprotein compare
MMP_RS08945 -3.4 -18.0 hypothetical protein compare
MMP_RS05515 -3.4 -13.6 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS02235 -3.3 -14.2 CBS domain-containing protein compare
MMP_RS06715 -3.3 -19.2 cache domain-containing protein compare
MMP_RS02240 -3.3 -5.9 methanogenesis marker 7 protein compare
MMP_RS08720 -3.3 -2.4 4Fe-4S binding protein compare
MMP_RS03015 -3.3 -12.6 GTP 3' 8-cyclase MoaA compare
MMP_RS05875 -3.3 -7.7 hydroxyethylthiazole kinase compare
MMP_RS08820 -3.3 -9.5 hypothetical protein compare
MMP_RS06345 -3.2 -12.5 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS01005 -3.2 -2.2 riboflavin synthase compare
MMP_RS07445 -3.1 -7.7 helix-turn-helix domain-containing protein compare
MMP_RS02010 -3.1 -12.7 PHP domain-containing protein compare
MMP_RS07005 -3.1 -1.0 4Fe-4S binding protein compare
MMP_RS04780 -3.1 -4.8 ribonuclease P compare
MMP_RS01020 -3.1 -1.8 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS06295 -3.1 -11.0 methanogenesis marker 14 protein compare
MMP_RS06105 -3.1 -16.0 hydrogenase maturation peptidase HycI compare
MMP_RS08745 -3.0 -9.9 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS07525 -3.0 -8.4 4Fe-4S binding protein compare
MMP_RS08790 -3.0 -3.5 translation initiation factor IF-2 subunit alpha compare
MMP_RS02645 -3.0 -14.5 ArsR family transcriptional regulator compare
MMP_RS05550 -3.0 -1.3 cation:proton antiporter compare
MMP_RS00130 -2.9 -1.7 nickel-responsive transcriptional regulator NikR compare
MMP_RS02195 -2.9 -7.3 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS06350 -2.9 -11.2 HesA/MoeB/ThiF family protein compare
MMP_RS07600 -2.9 -3.4 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS06175 -2.8 -10.2 winged helix-turn-helix transcriptional regulator compare
MMP_RS06720 -2.8 -8.3 response regulator transcription factor compare
MMP_RS00115 -2.8 -15.9 radical SAM protein compare
MMP_RS06625 -2.8 -3.0 DNA primase compare
MMP_RS02875 -2.7 -11.7 chorismate pyruvate-lyase family protein compare
MMP_RS07765 -2.7 -11.2 sodium:alanine symporter family protein compare
MMP_RS01500 -2.7 -3.7 CBS domain-containing protein compare
MMP_RS02650 -2.7 -10.4 flavodoxin family protein compare
MMP_RS01755 -2.7 -2.2 DUF2097 domain-containing protein compare
MMP_RS05510 -2.6 -12.3 Rrf2 family transcriptional regulator compare
MMP_RS01220 -2.6 -10.4 hypothetical protein compare
MMP_RS03640 -2.6 -6.5 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS08000 -2.6 -17.3 methyl coenzyme M reductase-arginine methyltransferase Mmp10 compare
MMP_RS06270 -2.5 -6.9 TIGR00300 family protein compare
MMP_RS01610 -2.5 -4.4 hypothetical protein compare
MMP_RS07365 -2.5 -15.3 2-phosphoglycerate kinase compare
MMP_RS04710 -2.4 -2.2 hypothetical protein compare
MMP_RS04585 -2.4 -8.9 AIR synthase related protein compare
MMP_RS08635 -2.4 -3.3 UbiA family prenyltransferase compare
MMP_RS02190 -2.4 -3.3 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS06020 -2.3 -8.2 archaeoflavoprotein AfpA compare
MMP_RS02110 -2.3 -3.0 hypothetical protein compare
MMP_RS06340 -2.3 -10.2 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS02340 -2.3 -2.7 DNA-directed RNA polymerase subunit E'' compare
MMP_RS07545 -2.2 -1.9 HTH domain-containing protein compare
MMP_RS00515 -2.2 -1.7 DUF655 domain-containing protein compare
MMP_RS02345 -2.2 -4.0 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS00295 -2.1 -2.7 gamma carbonic anhydrase family protein compare
MMP_RS03025 -2.1 -8.3 molybdenum cofactor guanylyltransferase compare
MMP_RS01385 -2.1 -1.0 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS01475 -2.1 -10.5 phosphosulfolactate synthase compare
MMP_RS08705 -2.1 -9.7 sulfopyruvate decarboxylase subunit beta compare
MMP_RS05245 -2.1 -10.3 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS08075 -2.1 -3.5 DUF749 domain-containing protein compare
MMP_RS06925 -2.0 -2.4 ribonuclease VapC4 compare
MMP_RS08715 -2.0 -3.0 formylmethanofuran dehydrogenase subunit B compare
MMP_RS06840 -2.0 -1.7 DNA-directed RNA polymerase subunit N compare
MMP_RS05850 -2.0 -6.8 Ldh family oxidoreductase compare
MMP_RS02280 -2.0 -1.5 DUF211 domain-containing protein compare
MMP_RS08210 -2.0 -3.6 phosphatidylglycerophosphatase A compare
MMP_RS01650 -1.9 -1.7 sulfurtransferase TusA family protein compare
MMP_RS07845 -1.9 -4.1 LL-diaminopimelate aminotransferase compare
MMP_RS01800 -1.9 -4.2 TIGR00303 family protein compare
MMP_RS06475 -1.9 -4.5 FAD-dependent oxidoreductase compare
MMP_RS08240 -1.9 -7.3 methanogenesis marker 16 metalloprotein compare
MMP_RS00895 -1.9 -4.1 hypothetical protein compare
MMP_RS07380 -1.9 -3.5 transcription elongation factor Spt5 compare
MMP_RS01265 -1.9 -2.2 hypothetical protein compare
MMP_RS06705 -1.9 -8.7 formate/nitrite transporter family protein compare
MMP_RS05540 -1.8 -3.0 hypothetical protein compare
MMP_RS06120 -1.8 -3.0 UPF0147 family protein compare
MMP_RS07775 -1.8 -8.5 alanine dehydrogenase compare
MMP_RS08460 -1.8 -2.3 proteasome-activating nucleotidase compare
MMP_RS03155 -1.8 -8.8 precorrin-6A reductase compare
MMP_RS05700 -1.7 -8.8 TfuA-related McrA-glycine thioamidation protein compare
MMP_RS06230 -1.7 -3.2 helix-turn-helix domain-containing protein compare
MMP_RS01445 -1.7 -8.4 hypothetical protein compare
MMP_RS00620 -1.7 -6.3 4Fe-4S binding protein compare
MMP_RS03555 -1.6 -9.3 transcriptional regulator compare
MMP_RS03035 -1.6 -4.2 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS04775 -1.6 -3.5 adenosylhomocysteinase compare
MMP_RS09020 -1.6 -2.3 hypothetical protein compare
MMP_RS07735 -1.6 -1.4 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS00290 -1.6 -6.2 hypothetical protein compare
MMP_RS01250 -1.6 -4.8 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS00810 -1.6 -6.1 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS02900 -1.6 -0.8 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS08435 -1.6 -2.6 Era-like GTP-binding protein compare
MMP_RS05460 -1.6 -8.5 YcaO-related McrA-glycine thioamidation protein compare
MMP_RS06285 -1.6 -3.1 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS06170 -1.5 -6.1 ABC transporter ATP-binding protein compare
MMP_RS07350 -1.5 -1.4 preprotein translocase subunit Sec61beta compare
MMP_RS02165 -1.5 -8.8 tRNA-dihydrouridine synthase compare
MMP_RS05765 -1.5 -5.4 M42 family metallopeptidase compare
MMP_RS03580 -1.5 -4.3 signal recognition particle-docking protein FtsY compare
MMP_RS02780 -1.5 -6.1 hypothetical protein compare
MMP_RS04870 -1.5 -3.9 TIGR02253 family HAD-type hydrolase compare
MMP_RS04685 -1.5 -3.0 DUF126 domain-containing protein compare
MMP_RS01980 -1.4 -10.8 trimeric intracellular cation channel family protein compare
MMP_RS01325 -1.4 -2.4 dihydroneopterin aldolase family protein compare
MMP_RS07730 -1.4 -2.7 pyruvate synthase subunit beta compare
MMP_RS00750 -1.4 -2.8 fumarate hydratase compare
MMP_RS04955 -1.4 -4.8 DNA topoisomerase I compare
MMP_RS08200 -1.4 -10.9 archaeosine synthase subunit alpha compare
MMP_RS08195 -1.4 -6.7 hypothetical protein compare
MMP_RS01380 -1.4 -4.7 PHP domain-containing protein compare
MMP_RS08650 -1.4 -2.8 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS08320 -1.3 -7.4 molybdopterin molybdotransferase MoeA compare
MMP_RS00110 -1.3 -3.7 hypothetical protein compare
MMP_RS00725 -1.3 -7.6 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS05845 -1.3 -2.1 tRNA-intron lyase compare
MMP_RS01365 -1.3 -2.5 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS05285 -1.3 -3.6 MMPL family transporter compare
MMP_RS06730 -1.3 -1.3 phosphopantothenate/pantothenate synthetase compare
MMP_RS02135 -1.3 -3.3 DUF5612 domain-containing protein compare
MMP_RS04605 -1.3 -3.6 cobalt ECF transporter T component CbiQ compare
MMP_RS03700 -1.3 -6.2 sodium:proton antiporter compare
MMP_RS01180 -1.2 -0.8 XTP/dITP diphosphatase compare
MMP_RS06895 -1.2 -1.7 selenocysteine-specific translation elongation factor compare
MMP_RS03205 -1.2 -1.2 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS06130 -1.2 -3.4 peptidylprolyl isomerase compare
MMP_RS07685 -1.2 -3.7 TIGR01212 family radical SAM protein compare
MMP_RS06865 -1.2 -1.9 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS00685 -1.2 -4.1 2-phospho-L-lactate guanylyltransferase compare
MMP_RS01720 -1.2 -1.0 replication factor C large subunit compare
MMP_RS08940 -1.1 -1.5 MetS family NSS transporter small subunit compare
MMP_RS05445 -1.1 -5.8 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS05430 -1.1 -3.7 TIGR00288 family NYN domain-containing protein compare
MMP_RS07200 -1.1 -4.6 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS00305 -1.1 -1.6 phosphoribosyl-ATP diphosphatase compare
MMP_RS07755 -1.1 -1.4 DUF555 domain-containing protein compare
MMP_RS01890 -1.1 -3.7 nucleotide sugar dehydrogenase compare
MMP_RS06885 -1.1 -1.7 50S ribosome-binding GTPase compare
MMP_RS05250 -1.1 -1.2 NFYB/HAP3 family transcription factor subunit compare
MMP_RS00985 -1.1 -4.0 CDC48 family AAA ATPase compare
MMP_RS01985 -1.1 -3.6 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS00730 -1.1 -4.5 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS03560 -1.1 -8.8 Na+/H+ antiporter NhaC family protein compare
MMP_RS05280 -1.1 -6.1 COG1361 S-layer family protein compare
MMP_RS00320 -1.1 -2.1 class I SAM-dependent methyltransferase compare
MMP_RS06480 -1.1 -4.4 ABC transporter substrate-binding protein compare
MMP_RS00915 -1.1 -4.9 DUF116 domain-containing protein compare
MMP_RS06860 -1.0 -1.8 4Fe-4S binding protein compare
MMP_RS03145 -1.0 -5.1 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS01085 -1.0 -1.9 hypothetical protein compare
MMP_RS07425 -1.0 -3.9 GTP-binding protein compare
MMP_RS03400 -1.0 -2.4 archease compare
MMP_RS06110 -1.0 -3.4 ATP-dependent protease LonB compare
MMP_RS05020 -1.0 -3.0 hypothetical protein compare
MMP_RS05955 -1.0 -2.4 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS00735 -1.0 -3.5 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS08165 -1.0 -1.2 phosphoglycerate dehydrogenase compare
MMP_RS07355 -1.0 -1.0 transcription factor S compare
MMP_RS04620 -1.0 -5.8 cobalt transporter CbiM compare
MMP_RS03960 -1.0 -0.8 hypothetical protein compare
MMP_RS02145 -1.0 -4.4 winged helix-turn-helix transcriptional regulator compare
MMP_RS03685 -0.9 -6.9 Mrp/NBP35 family ATP-binding protein compare
MMP_RS04875 -0.9 -3.4 energy-converting hydrogenase B subunit P compare
MMP_RS08445 -0.9 -3.4 DUF2099 family protein compare
MMP_RS07605 -0.9 -2.4 diadenylate cyclase compare
MMP_RS03110 -0.9 -3.7 glycosyltransferase family 2 protein compare
MMP_RS07700 -0.9 -5.4 DUF1188 domain-containing protein compare
MMP_RS02885 -0.9 -7.0 molybdopterin biosynthesis protein compare
MMP_RS03600 -0.9 -1.4 triose-phosphate isomerase compare
MMP_RS04615 -0.9 -1.3 PDGLE domain-containing protein compare
MMP_RS07955 -0.9 -3.5 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS03305 -0.9 -3.8 winged helix-turn-helix domain-containing protein compare


Specific Phenotypes

For 5 genes in this experiment

For stress Sodium hypochlorite in Methanococcus maripaludis S2

For stress Sodium hypochlorite across organisms