Experiment set5IT006 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS05550		-2.2	-1.1	cation:proton antiporter
MMP_RS07735		-2.1	-1.3	2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
MMP_RS03445		-2.0	-1.4	methanogenesis marker 17 protein
MMP_RS06730		-1.5	-2.0	phosphopantothenate/pantothenate synthetase
MMP_RS02235		-1.4	-7.6	CBS domain-containing protein
MMP_RS01885		-1.3	-5.1	Gfo/Idh/MocA family oxidoreductase
MMP_RS07355		-1.2	-1.1	transcription factor S
MMP_RS06870		-1.2	-3.8	DedA family protein
MMP_RS07545		-1.1	-1.1	HTH domain-containing protein
MMP_RS07755		-1.1	-1.2	DUF555 domain-containing protein
MMP_RS01875		-1.0	-5.4	N-acetyltransferase
MMP_RS07555		-1.0	-0.7	monovalent cation/H+ antiporter subunit E
MMP_RS00515		-1.0	-1.0	DUF655 domain-containing protein
MMP_RS00750		-0.9	-1.7	fumarate hydratase
MMP_RS01955		-0.9	-1.4	hypothetical protein
MMP_RS06600		-0.9	-1.3	class III signal peptide-containing protein
MMP_RS06105		-0.8	-3.8	hydrogenase maturation peptidase HycI
MMP_RS05315		-0.8	-1.3	hypothetical protein
MMP_RS06110		-0.8	-1.7	ATP-dependent protease LonB
MMP_RS01830		-0.8	-1.0	tRNA-Val
MMP_RS01910		-0.8	-4.3	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
MMP_RS02195		-0.8	-2.3	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
MMP_RS08600		-0.7	-1.2	flagellar protein D
MMP_RS07075		-0.7	-2.8	phosphomannomutase/phosphoglucomutase
MMP_RS08165		-0.7	-1.5	phosphoglycerate dehydrogenase
MMP_RS01880		-0.7	-3.2	DegT/DnrJ/EryC1/StrS family aminotransferase
MMP_RS01100		-0.7	-1.4	ABC transporter ATP-binding protein
MMP_RS01970		-0.7	-4.6	TIGR04279 domain-containing protein
MMP_RS02280		-0.7	-0.7	DUF211 domain-containing protein
MMP_RS01725		-0.7	-2.3	class I SAM-dependent methyltransferase family protein
MMP_RS01570		-0.7	-1.1	hypothetical protein
MMP_RS02830		-0.7	-4.7	DUF432 domain-containing protein
MMP_RS08360		-0.7	-2.7	hypothetical protein
MMP_RS05850		-0.7	-2.7	Ldh family oxidoreductase
MMP_RS08745		-0.7	-2.4	CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
MMP_RS01890		-0.7	-2.0	nucleotide sugar dehydrogenase
MMP_RS07845		-0.7	-1.9	LL-diaminopimelate aminotransferase
MMP_RS01915		-0.6	-4.3	DUF354 domain-containing protein
MMP_RS02345		-0.6	-1.6	GTP-dependent dephospho-CoA kinase family protein
MMP_RS01905		-0.6	-4.2	glycosyltransferase
MMP_RS01085		-0.6	-1.2	hypothetical protein
MMP_RS08460		-0.6	-1.3	proteasome-activating nucleotidase
MMP_RS01920		-0.6	-4.4	glycosyltransferase family 2 protein
MMP_RS00675		-0.6	-0.7	nitroreductase family protein
MMP_RS01225		-0.6	-2.1	DUF5379 domain-containing protein
MMP_RS08415		-0.6	-2.2	radical SAM protein
MMP_RS02955		-0.6	-1.4	DJ-1/PfpI family protein
MMP_RS02400		-0.6	-4.2	site-2 protease family protein
MMP_RS02145		-0.6	-2.5	winged helix-turn-helix transcriptional regulator
MMP_RS08790		-0.6	-1.0	translation initiation factor IF-2 subunit alpha
MMP_RS06525		-0.6	-0.9	YciI family protein
MMP_RS00125		-0.6	-1.0	DUF2798 domain-containing protein
MMP_RS03440		-0.5	-0.7	MoaD/ThiS family protein
MMP_RS03600		-0.5	-1.1	triose-phosphate isomerase
MMP_RS05515		-0.5	-2.2	cyclic pyranopterin monophosphate synthase MoaC
MMP_RS06530		-0.5	-2.1	bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
MMP_RS06035		-0.5	-3.3	glycosyltransferase family 2 protein
MMP_RS07380		-0.5	-0.9	transcription elongation factor Spt5
MMP_RS08345		-0.5	-3.0	4Fe-4S binding protein
MMP_RS03065		-0.5	-1.0	AzlC family ABC transporter permease
MMP_RS02175		-0.5	-0.5	DUF1611 domain-containing protein
MMP_RS02975		-0.5	-1.6	DUF2124 domain-containing protein
MMP_RS06020		-0.5	-1.1	archaeoflavoprotein AfpA
MMP_RS01925		-0.5	-2.6	DUF1616 domain-containing protein
MMP_RS02745		-0.5	-1.1	hypothetical protein
MMP_RS08240		-0.5	-2.1	methanogenesis marker 16 metalloprotein
MMP_RS04090		-0.5	-0.8	hypothetical protein
MMP_RS00530		-0.5	-2.2	tRNA pseudouridine(54/55) synthase Pus10
MMP_RS03495		-0.5	-2.9	Na/Pi cotransporter family protein
MMP_RS00915		-0.5	-1.9	DUF116 domain-containing protein
MMP_RS01005		-0.4	-0.6	riboflavin synthase
MMP_RS00320		-0.4	-0.8	class I SAM-dependent methyltransferase
MMP_RS02825		-0.4	-3.2	mechanosensitive ion channel family protein
MMP_RS08300		-0.4	-0.5	metal-sulfur cluster assembly factor
MMP_RS05555		-0.4	-0.8	DUF4040 domain-containing protein
MMP_RS03960		-0.4	-0.4	hypothetical protein
MMP_RS06400		-0.4	-0.8	4Fe-4S binding protein
MMP_RS00880		-0.4	-1.5	ribosome assembly RNA-binding protein YhbY
MMP_RS03305		-0.4	-1.7	winged helix-turn-helix domain-containing protein
MMP_RS01055		-0.4	-2.0	hypothetical protein
MMP_RS08335		-0.4	-2.4	NADH-quinone oxidoreductase subunit B family protein
MMP_RS06375		-0.4	-2.5	ATP-dependent sacrificial sulfur transferase LarE
MMP_RS04875		-0.4	-1.6	energy-converting hydrogenase B subunit P
MMP_RS06590		-0.4	-1.3	GNAT family N-acetyltransferase
MMP_RS00570		-0.4	-1.1	protein-L-isoaspartate O-methyltransferase
MMP_RS03420		-0.4	-1.2	acetolactate synthase small subunit
MMP_RS02965		-0.4	-1.6	carboxymuconolactone decarboxylase family protein
MMP_RS08830		-0.4	-1.4	GTP-binding protein
MMP_RS02245		-0.4	-1.1	hypothetical protein
MMP_RS07970		-0.4	-1.4	hypothetical protein
MMP_RS04260		-0.4	-1.6	coenzyme F420 hydrogenase subunit gamma
MMP_RS08275		-0.4	-2.8	hypothetical protein
MMP_RS01900		-0.4	-2.7	hypothetical protein
MMP_RS03125		-0.4	-1.4	cell division ATPase MinD
MMP_RS08350		-0.4	-0.5	hypothetical protein
MMP_RS01105		-0.4	-1.8	hypothetical protein
MMP_RS06310		-0.4	-1.2	NAD(P)/FAD-dependent oxidoreductase
MMP_RS07725		-0.4	-0.6	4Fe-4S dicluster domain-containing protein
MMP_RS06175		-0.4	-1.7	winged helix-turn-helix transcriptional regulator
MMP_RS03015		-0.4	-2.3	GTP 3' 8-cyclase MoaA
MMP_RS01430		-0.4	-2.8	mechanosensitive ion channel family protein
MMP_RS04720		-0.4	-0.9	DedA family protein
MMP_RS02895		-0.4	-2.2	DHH family phosphoesterase
MMP_RS03120		-0.4	-1.1	hypothetical protein
MMP_RS00685		-0.4	-1.1	2-phospho-L-lactate guanylyltransferase
MMP_RS01265		-0.4	-1.1	hypothetical protein
MMP_RS03155		-0.4	-1.6	precorrin-6A reductase
MMP_RS04500		-0.4	-2.5	adenosylmethionine--8-amino-7-oxononanoate transaminase
MMP_RS00830		-0.4	-1.2	purine phosphoribosyltransferase family protein
MMP_RS06290		-0.4	-1.2	DNA repair and recombination protein RadA
MMP_RS06670		-0.4	-1.3	glucose-6-phosphate isomerase
MMP_RS03315		-0.4	-0.2	ferrous iron transport protein A
MMP_RS07600		-0.4	-0.6	Ni-sirohydrochlorin a c-diamide synthase
MMP_RS01660		-0.3	-0.9	hypothetical protein
MMP_RS03460		-0.3	-2.2	U32 family peptidase
MMP_RS05965		-0.3	-0.9	carboxymuconolactone decarboxylase family protein
MMP_RS02960		-0.3	-2.2	class I SAM-dependent methyltransferase family protein
MMP_RS00430		-0.3	-1.1	hypothetical protein
MMP_RS00640		-0.3	-1.9	ABC transporter substrate-binding protein
MMP_RS01895		-0.3	-2.3	flippase
MMP_RS02265		-0.3	-1.1	nitroreductase family protein
MMP_RS02605		-0.3	-0.4	MotA/TolQ/ExbB proton channel family protein
MMP_RS00145		-0.3	-1.9	ATP-dependent Clp protease proteolytic subunit
MMP_RS00080		-0.3	-1.0	RecB-family nuclease
MMP_RS06485		-0.3	-0.4	zinc ribbon domain-containing protein
MMP_RS00865		-0.3	-1.7	SLC13 family permease
MMP_RS03450		-0.3	-0.8	glycine synthesis protein GlyXS (from data)
MMP_RS06340		-0.3	-1.8	phosphoadenosine phosphosulfate reductase family protein
MMP_RS05685		-0.3	-1.5	winged helix-turn-helix domain-containing protein
MMP_RS03490		-0.3	-0.7	DUF2115 domain-containing protein
MMP_RS06005		-0.3	-0.9	heavy-metal-associated domain-containing protein
MMP_RS07350		-0.3	-0.6	preprotein translocase subunit Sec61beta
MMP_RS03435		-0.3	-0.6	ketol-acid reductoisomerase
MMP_RS07955		-0.3	-1.3	FumA C-terminus/TtdB family hydratase beta subunit
MMP_RS08930		-0.3	-0.7	hypothetical protein
MMP_RS07795		-0.3	-2.1	site-2 protease family protein
MMP_RS05780		-0.3	-1.8	multidrug resistance efflux transporter family protein
MMP_RS05950		-0.3	-2.1	nickel-dependent hydrogenase large subunit
MMP_RS08100		-0.3	-1.6	8-amino-7-oxononanoate synthase
MMP_RS03080		-0.3	-1.2	universal stress protein
MMP_RS01645		-0.3	-1.1	SWIM zinc finger family protein
MMP_RS02885		-0.3	-1.9	molybdopterin biosynthesis protein
MMP_RS05140		-0.3	-1.1	helix-turn-helix transcriptional regulator
MMP_RS03895		-0.3	-0.8	hypothetical protein
MMP_RS01650		-0.3	-0.4	sulfurtransferase TusA family protein
MMP_RS07815		-0.3	-0.5	DUF2120 domain-containing protein
MMP_RS08320		-0.3	-1.2	molybdopterin molybdotransferase MoeA
MMP_RS00110		-0.3	-0.7	hypothetical protein
MMP_RS04945		-0.3	-1.3	hypothetical protein
MMP_RS02930		-0.3	-0.5	class I SAM-dependent methyltransferase
MMP_RS08290		-0.3	-1.3	DNA-binding protein Alba
MMP_RS03220		-0.3	-0.9	RNA 2' 3'-cyclic phosphodiesterase
MMP_RS08210		-0.3	-0.6	phosphatidylglycerophosphatase A
MMP_RS05875		-0.3	-1.6	hydroxyethylthiazole kinase
MMP_RS03620		-0.3	-1.7	hypothetical protein
MMP_RS01465		-0.3	-0.5	hypothetical protein
MMP_RS08355		-0.3	-0.9	Na(+)/H(+) antiporter subunit B
MMP_RS07385		-0.3	-0.4	protein translocase SEC61 complex subunit gamma
MMP_RS01975		-0.3	-2.0	hypothetical protein
MMP_RS00480		-0.3	-1.6	hypothetical protein
MMP_RS06190		-0.3	-1.2	tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO
MMP_RS02045		-0.3	-0.5	tRNA-Met
MMP_RS01275		-0.3	-1.2	class III signal peptide-containing protein
MMP_RS05640		-0.3	-1.5	UTP--glucose-1-phosphate uridylyltransferase GalU
MMP_RS03565		-0.3	-1.6	uracil phosphoribosyltransferase
MMP_RS07890		-0.3	-0.6	OB-fold nucleic acid binding domain-containing protein
MMP_RS05580		-0.3	-2.2	glycosyltransferase
MMP_RS07985		-0.3	-1.6	nitroreductase family protein
MMP_RS01795		-0.3	-0.2	methanogenesis marker 6 protein
MMP_RS06075		-0.3	-1.5	class I SAM-dependent methyltransferase
MMP_RS08620		-0.3	-1.3	flagellar accessory protein FlaH
MMP_RS06215		-0.3	-0.5	30S ribosomal protein S6e
MMP_RS08610		-0.3	-1.6	flagellar protein F
MMP_RS02440		-0.3	-0.7	hypothetical protein
MMP_RS08395		-0.3	-1.6	DsrE family protein
MMP_RS06300		-0.3	-1.6	ABC transporter substrate-binding protein
MMP_RS01490		-0.3	-0.9	tetratricopeptide repeat protein
MMP_RS07635		-0.3	-1.0	MogA/MoaB family molybdenum cofactor biosynthesis protein
MMP_RS04495		-0.2	-1.2	cation:proton antiporter
MMP_RS07905		-0.2	-1.1	DUF3343 domain-containing protein
MMP_RS01935		-0.2	-1.6	DUF58 domain-containing protein
MMP_RS00965		-0.2	-0.8	hypothetical protein
MMP_RS07900		-0.2	-0.7	YeeE/YedE family protein
MMP_RS06520		-0.2	-1.0	DUF1786 domain-containing protein
MMP_RS02550		-0.2	-1.0	helix-turn-helix transcriptional regulator
MMP_RS01495		-0.2	-1.7	TraB/GumN family protein
MMP_RS07730		-0.2	-0.4	pyruvate synthase subunit beta
MMP_RS00980		-0.2	-1.8	hypothetical protein
MMP_RS07705		-0.2	-1.2	transcriptional regulator
MMP_RS06940		-0.2	-0.5	polyprenyl diphosphate synthase
MMP_RS03265		-0.2	-1.7	sugar phosphate isomerase/epimerase
MMP_RS05110		-0.2	-1.4	16S ribosomal RNA methyltransferase A
MMP_RS04685		-0.2	-0.8	DUF126 domain-containing protein
MMP_RS08655		-0.2	-1.7	phosphoadenosine phosphosulfate reductase family protein
MMP_RS04125		-0.2	-1.4	TetR/AcrR family transcriptional regulator
MMP_RS06120		-0.2	-0.4	UPF0147 family protein
MMP_RS01630		-0.2	-0.9	N-glycosylase/DNA lyase
MMP_RS08280		-0.2	-0.7	proteasome assembly chaperone family protein
MMP_RS03230		-0.2	-1.2	flavodoxin family protein
MMP_RS06610		-0.2	-0.8	DUF2334 domain-containing protein

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress sodium iodate across organisms