Experiment set5IT005 for Klebsiella michiganensis M5al

Compare to:

Sodium D,L-Lactate carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS20355 -8.2 -5.6 colicin V production protein compare
BWI76_RS18940 -7.4 -5.1 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS04675 -7.1 -6.9 3-isopropylmalate dehydrogenase compare
BWI76_RS05840 -7.0 -4.8 glutamate 5-kinase compare
BWI76_RS18930 -6.9 -4.5 histidinol-phosphate transaminase compare
BWI76_RS04470 -6.8 -8.1 carbamoyl phosphate synthase large subunit compare
BWI76_RS04465 -6.7 -4.7 carbamoyl-phosphate synthase small subunit compare
BWI76_RS00980 -6.7 -8.0 PLP-dependent threonine dehydratase compare
BWI76_RS18920 -6.7 -4.6 ATP phosphoribosyltransferase compare
BWI76_RS09755 -6.7 -7.9 phosphoserine transaminase compare
BWI76_RS11965 -6.6 -6.3 orotidine-5'-phosphate decarboxylase compare
BWI76_RS02815 -6.5 -4.4 fructose-bisphosphatase class I compare
BWI76_RS05835 -6.3 -4.4 gamma-glutamyl-phosphate reductase compare
BWI76_RS20895 -6.2 -6.0 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS23220 -6.1 -7.9 amino-acid N-acetyltransferase compare
BWI76_RS04250 -6.0 -8.0 homoserine kinase compare
BWI76_RS04160 -6.0 -6.3 phosphoserine phosphatase compare
BWI76_RS08385 -5.9 -3.4 citrate (Si)-synthase compare
BWI76_RS18935 -5.9 -7.0 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS04670 -5.9 -10.5 3-isopropylmalate dehydratase large subunit compare
BWI76_RS18955 -5.7 -5.7 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS07070 -5.7 -5.5 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS21265 -5.7 -15.0 phosphoribosylformylglycinamidine synthase compare
BWI76_RS01615 -5.7 -10.9 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS11850 -5.6 -7.5 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS26085 -5.6 -3.8 3-dehydroquinate synthase compare
BWI76_RS18925 -5.6 -7.6 histidinol dehydrogenase compare
BWI76_RS00805 -5.6 -4.6 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS04685 -5.6 -10.7 putative leucine operon leader peptide compare
BWI76_RS20350 -5.5 -4.8 amidophosphoribosyltransferase compare
BWI76_RS00835 -5.5 -15.0 phosphoenolpyruvate carboxylase compare
BWI76_RS04245 -5.4 -15.3 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS23920 -5.4 -6.0 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS04255 -5.4 -9.7 threonine synthase compare
BWI76_RS21475 -5.4 -6.9 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS07065 -5.3 -6.7 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS01655 -5.3 -8.2 homoserine O-succinyltransferase compare
BWI76_RS23360 -5.2 -5.1 diaminopimelate decarboxylase compare
BWI76_RS00850 -5.2 -8.7 acetylglutamate kinase compare
BWI76_RS24285 -5.2 -7.4 cystathionine beta-lyase compare
BWI76_RS20965 -5.1 -4.2 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS02995 -5.0 -9.1 aspartate carbamoyltransferase compare
BWI76_RS01610 -5.0 -6.7 phosphoribosylamine--glycine ligase compare
BWI76_RS00785 -5.0 -6.0 cystathionine gamma-synthase compare
BWI76_RS00990 -4.9 -10.0 ketol-acid reductoisomerase compare
BWI76_RS04665 -4.9 -19.5 3-isopropylmalate dehydratase small subunit compare
BWI76_RS11840 -4.8 -4.0 tryptophan synthase subunit alpha compare
BWI76_RS04645 -4.8 -7.6 3-dehydroquinase compare
BWI76_RS25115 -4.8 -5.3 argininosuccinate synthase compare
BWI76_RS18950 -4.7 -5.5 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS04680 -4.7 -9.9 2-isopropylmalate synthase compare
BWI76_RS11860 -4.7 -6.6 anthranilate synthase component I compare
BWI76_RS10990 -4.6 -4.5 dihydroorotase compare
BWI76_RS09760 -4.6 -6.6 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS05015 -4.5 -3.4 transcriptional regulator compare
BWI76_RS11855 -4.5 -7.5 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS09910 -4.5 -17.5 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS17065 -4.4 -7.9 phosphoenolpyruvate synthase conserved
BWI76_RS11845 -4.4 -1.9 tryptophan synthase subunit beta compare
BWI76_RS04240 -4.4 -2.0 thr operon leader peptide compare
BWI76_RS00845 -4.2 -8.7 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS23365 -4.2 -5.3 LysR family transcriptional regulator compare
BWI76_RS00855 -4.1 -8.0 argininosuccinate lyase compare
BWI76_RS00975 -4.1 -6.2 dihydroxy-acid dehydratase compare
BWI76_RS21465 -4.1 -5.5 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS22755 -4.0 -6.4 phosphoadenosine phosphosulfate reductase compare
BWI76_RS23885 -3.9 -2.1 2-octaprenylphenol hydroxylase compare
BWI76_RS22765 -3.9 -16.0 sulfite reductase subunit alpha compare
BWI76_RS09660 -3.8 -2.6 DNA translocase FtsK compare
BWI76_RS03010 -3.8 -5.2 ornithine carbamoyltransferase compare
BWI76_RS22760 -3.8 -7.5 sulfite reductase subunit beta compare
BWI76_RS00985 -3.8 -6.8 transcriptional regulator IlvY compare
BWI76_RS20435 -3.8 -2.2 chorismate synthase compare
BWI76_RS04705 -3.7 -8.6 DNA-binding transcriptional regulator FruR compare
BWI76_RS27385 -3.7 -8.0 orotate phosphoribosyltransferase compare
BWI76_RS01210 -3.6 -4.5 tyrosine recombinase XerC compare
BWI76_RS00400 -3.5 -2.3 glutamine synthetase compare
BWI76_RS27185 -3.5 -11.9 L-lactate/D-lactate permease (from data) conserved
BWI76_RS09645 -3.5 -2.0 thioredoxin-disulfide reductase compare
BWI76_RS15825 -3.4 -2.3 hypothetical protein compare
BWI76_RS00965 -3.4 -2.0 acetolactate synthase 2 small subunit compare
BWI76_RS02735 -3.4 -6.4 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS27190 -3.3 -6.4 transcriptional regulator LldR conserved
BWI76_RS01185 -3.3 -2.3 adenylate cyclase compare
BWI76_RS23230 -3.2 -3.1 exodeoxyribonuclease V subunit beta compare
BWI76_RS20640 -3.1 -7.1 cysteine synthase A compare
BWI76_RS22690 -3.1 -3.9 adenylyl-sulfate kinase compare
BWI76_RS23240 -2.9 -4.4 exonuclease V subunit gamma compare
BWI76_RS27390 -2.9 -3.7 ribonuclease PH compare
BWI76_RS00180 -2.4 -2.7 F0F1 ATP synthase subunit epsilon compare
BWI76_RS06185 -2.4 -9.8 shikimate kinase II compare
BWI76_RS05200 -2.4 -3.7 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS00345 -2.3 -3.8 protein disulfide oxidoreductase DsbA compare
BWI76_RS17300 -2.3 -2.8 tRNA-Tyr compare
BWI76_RS08425 -2.2 -3.9 succinyl-CoA ligase subunit beta compare
BWI76_RS26055 -2.2 -7.7 siroheme synthase compare
BWI76_RS03080 -2.1 -3.6 (Fe-S)-cluster assembly protein compare
BWI76_RS27430 -2.1 -1.9 (p)ppGpp synthetase compare
BWI76_RS17720 -2.0 -2.0 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS20440 -2.0 -1.9 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS08395 -1.9 -2.6 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS08430 -1.8 -5.1 succinate--CoA ligase subunit alpha compare
BWI76_RS26570 -1.8 -3.3 anion permease compare
BWI76_RS25960 -1.8 -5.0 NUDIX hydrolase compare
BWI76_RS14835 -1.7 -1.4 hypothetical protein compare
BWI76_RS26175 -1.7 -4.3 DeoR/GlpR family transcriptional regulator compare
BWI76_RS18605 -1.6 -1.6 oxidoreductase molybdopterin-binding protein compare
BWI76_RS21140 -1.6 -2.6 molecular chaperone HscA compare
BWI76_RS08405 -1.6 -3.3 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS20650 -1.6 -2.5 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS19840 -1.5 -1.6 hypothetical protein compare
BWI76_RS15135 -1.5 -4.6 hypothetical protein compare
BWI76_RS26075 -1.5 -2.9 DNA adenine methylase compare
BWI76_RS24900 -1.5 -1.8 DeoR family transcriptional regulator compare
BWI76_RS22695 -1.4 -3.4 sulfate adenylyltransferase compare
BWI76_RS03880 -1.4 -3.4 homoprotocatechuate degradation operon regulator, HpaR compare
BWI76_RS02610 -1.4 -4.8 transcriptional regulator compare
BWI76_RS03415 -1.4 -6.1 LacI family transcriptional regulator compare
BWI76_RS06485 -1.4 -3.0 cytochrome o ubiquinol oxidase subunit III compare
BWI76_RS11610 -1.4 -3.2 glutamate dehydrogenase compare
BWI76_RS26460 -1.3 -4.5 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS15835 -1.3 -0.9 hypothetical protein compare
BWI76_RS25320 -1.3 -6.3 glutamate synthase compare
BWI76_RS20995 -1.3 -2.6 RNA degradosome polyphosphate kinase compare
BWI76_RS26455 -1.3 -3.5 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS06340 -1.3 -1.4 hypothetical protein compare
BWI76_RS19330 -1.3 -1.3 HAD family hydrolase compare
BWI76_RS06730 -1.3 -2.0 lac repressor compare
BWI76_RS23480 -1.3 -7.8 EAL domain-containing protein compare
BWI76_RS25070 -1.3 -1.5 hypothetical protein compare
BWI76_RS08730 -1.3 -1.7 histidine utilization repressor compare
BWI76_RS23265 -1.3 -3.6 hypothetical protein compare
BWI76_RS15830 -1.2 -2.0 hypothetical protein compare
BWI76_RS21115 -1.2 -2.3 3-mercaptopyruvate sulfurtransferase compare
BWI76_RS15620 -1.2 -1.9 hypothetical protein compare
BWI76_RS03225 -1.2 -6.1 transcriptional regulator compare
BWI76_RS26000 -1.2 -6.3 aspartate aminotransferase family protein compare
BWI76_RS15060 -1.2 -2.5 MarR family transcriptional regulator compare
BWI76_RS00355 -1.2 -3.4 DNA polymerase I compare
BWI76_RS00960 -1.2 -4.4 acetolactate synthase 2 catalytic subunit compare
BWI76_RS08390 -1.2 -1.5 hypothetical protein compare
BWI76_RS26390 -1.2 -3.4 cell division protein FtsX compare
BWI76_RS20970 -1.1 -1.5 phosphoribosylglycinamide formyltransferase compare
BWI76_RS24850 -1.1 -5.5 DeoR family transcriptional regulator compare
BWI76_RS02530 -1.1 -1.1 tRNA dimethylallyltransferase compare
BWI76_RS09640 -1.1 -3.2 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD compare
BWI76_RS27875 -1.1 -1.3 membrane protein compare
BWI76_RS22240 -1.1 -4.0 transcriptional regulator compare
BWI76_RS11335 -1.1 -1.3 tautomerase compare
BWI76_RS25315 -1.1 -6.3 glutamate synthase large subunit compare
BWI76_RS11170 -1.1 -1.2 hypothetical protein compare
BWI76_RS16805 -1.1 -1.7 basic amino acid ABC transporter substrate-binding protein compare
BWI76_RS09190 -1.1 -3.4 hypothetical protein compare
BWI76_RS16315 -1.1 -2.0 SirA-like protein compare
BWI76_RS23830 -1.1 -4.7 hypothetical protein compare
BWI76_RS12550 -1.1 -1.9 hypothetical protein compare
BWI76_RS20910 -1.1 -4.6 glycine cleavage system transcriptional repressor compare
BWI76_RS22420 -1.1 -2.4 LacI family transcriptional regulator compare
BWI76_RS14075 -1.1 -1.2 TetR family transcriptional regulator compare
BWI76_RS27440 -1.1 -2.6 DNA helicase RecG compare
BWI76_RS11235 -1.1 -1.2 hypothetical protein compare
BWI76_RS04715 -1.1 -1.6 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS06490 -1.0 -2.4 cytochrome ubiquinol oxidase subunit I compare
BWI76_RS19685 -1.0 -4.2 lysine transporter compare
BWI76_RS18390 -1.0 -2.6 hypothetical protein compare
BWI76_RS01170 -1.0 -3.2 uroporphyrinogen-III C-methyltransferase compare
BWI76_RS05120 -1.0 -4.8 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS18165 -1.0 -1.1 NUDIX pyrophosphatase compare
BWI76_RS19325 -1.0 -1.4 mandelate racemase compare
BWI76_RS15730 -1.0 -2.6 hypothetical protein compare
BWI76_RS27605 -1.0 -1.6 hypothetical protein compare
BWI76_RS15845 -1.0 -1.2 hypothetical protein compare
BWI76_RS20150 -1.0 -1.3 NADH:ubiquinone oxidoreductase subunit J compare
BWI76_RS25645 -1.0 -3.7 shikimate dehydrogenase compare
BWI76_RS18140 -1.0 -1.9 zinc ABC transporter permease compare
BWI76_RS21290 -1.0 -4.0 DNA-binding transcriptional regulator compare
BWI76_RS17195 -1.0 -2.1 hypothetical protein compare
BWI76_RS24025 -1.0 -4.9 agmatinase compare
BWI76_RS22805 -1.0 -4.8 GTP diphosphokinase compare
BWI76_RS18855 -1.0 -1.9 cysteine desulfurase NifS compare
BWI76_RS00140 -1.0 -1.0 phosphate transport system regulator PhoU compare
BWI76_RS00390 -0.9 -1.9 two-component system sensor histidine kinase NtrB compare
BWI76_RS20270 -0.9 -3.0 hypothetical protein compare
BWI76_RS19730 -0.9 -1.4 1-phosphofructokinase compare
BWI76_RS21580 -0.9 -1.7 SsrA-binding protein compare
BWI76_RS15840 -0.9 -1.8 prophage protein compare
BWI76_RS27195 -0.9 -3.2 alpha-hydroxy-acid oxidizing enzyme compare
BWI76_RS09635 -0.9 -1.5 amino acid ABC transporter ATP-binding protein compare
BWI76_RS21480 -0.9 -2.2 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS01885 -0.9 -1.2 CsbD family protein compare
BWI76_RS14435 -0.9 -0.9 glutamine ABC transporter ATP-binding protein compare
BWI76_RS26590 -0.9 -3.0 transcriptional regulator compare
BWI76_RS27475 -0.9 -4.7 regulatory protein GntR family protein compare
BWI76_RS19010 -0.9 -2.1 polysaccharide pyruvyl transferase yvff compare
BWI76_RS16760 -0.9 -3.0 lipase compare
BWI76_RS15635 -0.9 -3.6 hypothetical protein compare
BWI76_RS15955 -0.8 -5.1 transcriptional regulator compare
BWI76_RS27075 -0.8 -3.5 IclR family transcriptional regulator compare
BWI76_RS09870 -0.8 -3.5 aromatic amino acid aminotransferase compare
BWI76_RS20280 -0.8 -2.7 phosphodiesterase compare


Specific Phenotypes

For 3 genes in this experiment

For carbon source Sodium D,L-Lactate in Klebsiella michiganensis M5al

For carbon source Sodium D,L-Lactate across organisms