Experiment set5IT004 for Klebsiella michiganensis M5al

Compare to:

Sodium L-Lactate carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS20355 -8.3 -5.7 colicin V production protein compare
BWI76_RS09755 -7.2 -7.0 phosphoserine transaminase compare
BWI76_RS18920 -6.9 -4.8 ATP phosphoribosyltransferase compare
BWI76_RS18930 -6.8 -6.2 histidinol-phosphate transaminase compare
BWI76_RS04465 -6.7 -4.7 carbamoyl-phosphate synthase small subunit compare
BWI76_RS21475 -6.7 -7.3 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS04250 -6.6 -7.9 homoserine kinase compare
BWI76_RS04645 -6.6 -6.4 3-dehydroquinase compare
BWI76_RS18955 -6.6 -6.4 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS02815 -6.4 -4.4 fructose-bisphosphatase class I compare
BWI76_RS18950 -6.4 -5.7 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS05840 -6.3 -6.1 glutamate 5-kinase compare
BWI76_RS00805 -6.3 -4.5 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS04675 -6.2 -7.4 3-isopropylmalate dehydrogenase compare
BWI76_RS04670 -6.0 -9.9 3-isopropylmalate dehydratase large subunit compare
BWI76_RS04255 -5.9 -9.9 threonine synthase compare
BWI76_RS23360 -5.9 -4.1 diaminopimelate decarboxylase compare
BWI76_RS04685 -5.8 -11.1 putative leucine operon leader peptide compare
BWI76_RS18940 -5.8 -7.6 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS18925 -5.7 -8.2 histidinol dehydrogenase compare
BWI76_RS00980 -5.6 -11.3 PLP-dependent threonine dehydratase compare
BWI76_RS26085 -5.6 -3.8 3-dehydroquinate synthase compare
BWI76_RS00850 -5.5 -11.1 acetylglutamate kinase compare
BWI76_RS23365 -5.5 -5.8 LysR family transcriptional regulator compare
BWI76_RS18935 -5.4 -10.3 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS09760 -5.3 -6.0 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS21265 -5.3 -13.0 phosphoribosylformylglycinamidine synthase compare
BWI76_RS08385 -5.2 -5.0 citrate (Si)-synthase compare
BWI76_RS27385 -5.2 -7.1 orotate phosphoribosyltransferase compare
BWI76_RS00990 -5.2 -10.5 ketol-acid reductoisomerase compare
BWI76_RS21465 -5.2 -5.3 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS01615 -5.1 -12.8 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS04245 -5.1 -15.8 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS01655 -5.1 -7.7 homoserine O-succinyltransferase compare
BWI76_RS00835 -5.1 -13.6 phosphoenolpyruvate carboxylase compare
BWI76_RS04160 -5.1 -5.4 phosphoserine phosphatase compare
BWI76_RS04665 -5.0 -21.0 3-isopropylmalate dehydratase small subunit compare
BWI76_RS11850 -5.0 -9.1 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS00845 -5.0 -7.8 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS20895 -5.0 -6.8 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS11965 -5.0 -5.4 orotidine-5'-phosphate decarboxylase compare
BWI76_RS05835 -5.0 -4.8 gamma-glutamyl-phosphate reductase compare
BWI76_RS10990 -5.0 -4.8 dihydroorotase compare
BWI76_RS23920 -5.0 -5.6 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS17065 -4.9 -12.6 phosphoenolpyruvate synthase compare
BWI76_RS11845 -4.7 -2.0 tryptophan synthase subunit beta compare
BWI76_RS11840 -4.7 -6.2 tryptophan synthase subunit alpha compare
BWI76_RS24285 -4.6 -8.2 cystathionine beta-lyase compare
BWI76_RS04470 -4.6 -11.5 carbamoyl phosphate synthase large subunit compare
BWI76_RS22755 -4.6 -10.1 phosphoadenosine phosphosulfate reductase compare
BWI76_RS00785 -4.5 -7.5 cystathionine gamma-synthase compare
BWI76_RS11855 -4.5 -7.5 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS00855 -4.5 -7.4 argininosuccinate lyase compare
BWI76_RS23220 -4.4 -6.7 amino-acid N-acetyltransferase compare
BWI76_RS04705 -4.4 -8.4 DNA-binding transcriptional regulator FruR compare
BWI76_RS00975 -4.4 -9.6 dihydroxy-acid dehydratase compare
BWI76_RS02995 -4.4 -7.9 aspartate carbamoyltransferase compare
BWI76_RS04680 -4.3 -11.7 2-isopropylmalate synthase compare
BWI76_RS22760 -4.2 -10.9 sulfite reductase subunit beta compare
BWI76_RS20350 -4.1 -9.8 amidophosphoribosyltransferase compare
BWI76_RS17720 -4.1 -2.4 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS20965 -4.0 -4.3 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS00985 -4.0 -8.1 transcriptional regulator IlvY compare
BWI76_RS22765 -4.0 -13.8 sulfite reductase subunit alpha compare
BWI76_RS09910 -4.0 -16.8 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS04240 -3.9 -2.7 thr operon leader peptide compare
BWI76_RS07065 -3.9 -9.5 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS01350 -3.9 -1.6 NAD(P)H-flavin reductase compare
BWI76_RS01210 -3.8 -3.6 tyrosine recombinase XerC compare
BWI76_RS09645 -3.8 -2.2 thioredoxin-disulfide reductase compare
BWI76_RS27390 -3.7 -4.6 ribonuclease PH compare
BWI76_RS05015 -3.7 -3.4 transcriptional regulator compare
BWI76_RS11860 -3.7 -10.2 anthranilate synthase component I compare
BWI76_RS01610 -3.7 -6.4 phosphoribosylamine--glycine ligase compare
BWI76_RS25115 -3.7 -5.6 argininosuccinate synthase compare
BWI76_RS00400 -3.5 -2.3 glutamine synthetase compare
BWI76_RS16275 -3.5 -3.2 fumarate hydratase FumA compare
BWI76_RS27185 -3.4 -12.0 L-lactate/D-lactate permease (from data) conserved
BWI76_RS23240 -3.4 -4.0 exonuclease V subunit gamma compare
BWI76_RS00965 -3.3 -2.0 acetolactate synthase 2 small subunit compare
BWI76_RS03010 -3.3 -7.6 ornithine carbamoyltransferase compare
BWI76_RS27195 -3.3 -6.6 alpha-hydroxy-acid oxidizing enzyme compare
BWI76_RS01185 -3.3 -2.2 adenylate cyclase compare
BWI76_RS02735 -3.2 -6.3 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS07070 -3.2 -4.5 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS00140 -3.2 -1.9 phosphate transport system regulator PhoU compare
BWI76_RS08405 -3.1 -5.1 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS20435 -3.0 -2.4 chorismate synthase compare
BWI76_RS23230 -3.0 -3.5 exodeoxyribonuclease V subunit beta compare
BWI76_RS27190 -2.8 -6.2 transcriptional regulator LldR conserved
BWI76_RS23895 -2.8 -2.9 Xaa-Pro aminopeptidase compare
BWI76_RS27430 -2.6 -2.1 (p)ppGpp synthetase compare
BWI76_RS20640 -2.5 -5.6 cysteine synthase A compare
BWI76_RS09660 -2.5 -3.1 DNA translocase FtsK compare
BWI76_RS22690 -2.4 -3.0 adenylyl-sulfate kinase compare
BWI76_RS20970 -2.3 -2.3 phosphoribosylglycinamide formyltransferase compare
BWI76_RS06015 -2.2 -2.5 hypothetical protein compare
BWI76_RS08395 -2.2 -2.9 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS23480 -2.2 -10.6 EAL domain-containing protein compare
BWI76_RS20440 -2.2 -1.4 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS21140 -2.1 -2.1 molecular chaperone HscA compare
BWI76_RS01200 -2.0 -2.6 diaminopimelate epimerase compare
BWI76_RS06185 -2.0 -10.3 shikimate kinase II compare
BWI76_RS26055 -1.9 -6.7 siroheme synthase compare
BWI76_RS22805 -1.9 -9.2 GTP diphosphokinase compare
BWI76_RS15825 -1.9 -3.1 hypothetical protein compare
BWI76_RS00180 -1.9 -1.6 F0F1 ATP synthase subunit epsilon compare
BWI76_RS08425 -1.8 -6.3 succinyl-CoA ligase subunit beta compare
BWI76_RS00240 -1.8 -2.4 FMN-binding protein MioC compare
BWI76_RS26075 -1.8 -4.2 DNA adenine methylase compare
BWI76_RS08535 -1.8 -2.9 translocation protein TolB compare
BWI76_RS05200 -1.7 -2.4 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS27440 -1.7 -4.4 DNA helicase RecG compare
BWI76_RS15835 -1.6 -1.1 hypothetical protein compare
BWI76_RS25645 -1.6 -6.3 shikimate dehydrogenase compare
BWI76_RS00960 -1.6 -6.0 acetolactate synthase 2 catalytic subunit compare
BWI76_RS26000 -1.6 -6.9 aspartate aminotransferase family protein compare
BWI76_RS09190 -1.6 -4.7 hypothetical protein compare
BWI76_RS23885 -1.5 -2.3 2-octaprenylphenol hydroxylase compare
BWI76_RS00390 -1.5 -3.3 two-component system sensor histidine kinase NtrB compare
BWI76_RS25315 -1.5 -7.5 glutamate synthase large subunit compare
BWI76_RS25160 -1.5 -2.1 transcription elongation factor GreA compare
BWI76_RS01385 -1.5 -2.3 potassium transporter compare
BWI76_RS22420 -1.5 -2.5 LacI family transcriptional regulator compare
BWI76_RS25320 -1.4 -4.5 glutamate synthase compare
BWI76_RS21480 -1.4 -3.0 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS16315 -1.4 -2.5 SirA-like protein compare
BWI76_RS08430 -1.4 -3.5 succinate--CoA ligase subunit alpha compare
BWI76_RS10745 -1.4 -1.4 hypothetical protein compare
BWI76_RS26875 -1.3 -3.1 dipeptide ABC transporter permease DppC compare
BWI76_RS25870 -1.3 -1.8 elongation factor Tu compare
BWI76_RS23830 -1.3 -5.1 hypothetical protein compare
BWI76_RS21310 -1.3 -1.3 DNA repair protein RecO compare
BWI76_RS00345 -1.3 -3.2 protein disulfide oxidoreductase DsbA compare
BWI76_RS02530 -1.3 -2.0 tRNA dimethylallyltransferase compare
BWI76_RS03880 -1.3 -3.5 homoprotocatechuate degradation operon regulator, HpaR compare
BWI76_RS04530 -1.3 -2.1 peptidylprolyl isomerase SurA compare
BWI76_RS00970 -1.3 -2.3 branched chain amino acid aminotransferase compare
BWI76_RS11780 -1.2 -3.1 2-deoxyglucose-6-phosphatase compare
BWI76_RS26190 -1.2 -3.6 glycerol-3-phosphate dehydrogenase compare
BWI76_RS26570 -1.2 -2.0 anion permease compare
BWI76_RS06485 -1.2 -2.7 cytochrome o ubiquinol oxidase subunit III compare
BWI76_RS02985 -1.2 -5.3 reactive intermediate/imine deaminase compare
BWI76_RS04715 -1.2 -1.8 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS15810 -1.2 -4.0 hypothetical protein compare
BWI76_RS06765 -1.2 -2.0 transcriptional regulator compare
BWI76_RS26460 -1.2 -3.5 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS25600 -1.2 -1.1 tRNA-Thr compare
BWI76_RS11900 -1.2 -1.3 cob(I)yrinic acid a,c-diamide adenosyltransferase compare
BWI76_RS25280 -1.1 -1.9 RNase adaptor protein RapZ compare
BWI76_RS08525 -1.1 -2.1 colicin transporter compare
BWI76_RS02410 -1.1 -1.5 EF-P beta-lysylation protein EpmB compare
BWI76_RS16955 -1.1 -1.7 hypothetical protein compare
BWI76_RS17980 -1.1 -3.9 RNA chaperone ProQ compare
BWI76_RS01220 -1.1 -3.5 DNA-dependent helicase II compare
BWI76_RS26175 -1.1 -2.5 DeoR/GlpR family transcriptional regulator compare
BWI76_RS26620 -1.1 -1.2 Fe-S biogenesis protein NfuA compare
BWI76_RS12450 -1.1 -3.0 phage shock protein PspA compare
BWI76_RS00385 -1.1 -4.9 nitrogen assimilation regulatory protein compare
BWI76_RS20995 -1.0 -2.0 RNA degradosome polyphosphate kinase compare
BWI76_RS08390 -1.0 -2.7 hypothetical protein compare
BWI76_RS21685 -1.0 -1.4 hypothetical protein compare
BWI76_RS01070 -1.0 -3.2 thiol reductase thioredoxin compare
BWI76_RS21165 -1.0 -1.7 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS20650 -1.0 -1.7 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS26685 -1.0 -3.1 glutathione-disulfide reductase compare
BWI76_RS01885 -1.0 -1.2 CsbD family protein compare
BWI76_RS12465 -1.0 -1.0 phage shock protein D compare
BWI76_RS14935 -1.0 -1.3 NIPSNAP family containing protein compare
BWI76_RS25060 -1.0 -2.2 lipoprotein NlpI compare
BWI76_RS12680 -1.0 -1.5 oxidoreductase compare
BWI76_RS15650 -1.0 -2.7 gp5 compare
BWI76_RS19850 -1.0 -2.3 tRNA-Pro compare
BWI76_RS15135 -0.9 -2.5 hypothetical protein compare
BWI76_RS19495 -0.9 -1.3 ABC transporter, quaternary amine uptake transporter (QAT) family, ATP-binding protein compare
BWI76_RS17805 -0.9 -1.1 membrane protein compare
BWI76_RS26395 -0.9 -3.3 cell division protein FtsE compare
BWI76_RS15955 -0.9 -6.9 transcriptional regulator compare
BWI76_RS06495 -0.9 -4.5 cytochrome ubiquinol oxidase subunit II compare
BWI76_RS05680 -0.9 -3.1 LacI family transcriptional regulator compare
BWI76_RS19685 -0.9 -3.9 lysine transporter compare
BWI76_RS16195 -0.9 -1.3 hypothetical protein compare
BWI76_RS19035 -0.9 -5.0 dTDP-rhamnosyl transferase compare
BWI76_RS00865 -0.9 -3.3 DNA-binding transcriptional regulator OxyR compare
BWI76_RS03415 -0.9 -4.3 LacI family transcriptional regulator compare
BWI76_RS21000 -0.9 -3.6 exopolyphosphatase compare
BWI76_RS13435 -0.9 -1.6 hypothetical protein compare
BWI76_RS15705 -0.9 -3.9 putative holin protein compare
BWI76_RS01095 -0.9 -1.7 UDP-N-acetyl-D-mannosamine dehydrogenase compare
BWI76_RS21370 -0.9 -1.6 ATP-dependent RNA helicase SrmB compare
BWI76_RS08520 -0.8 -1.4 colicin transporter TolQ compare
BWI76_RS26455 -0.8 -2.2 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS15060 -0.8 -3.0 MarR family transcriptional regulator compare
BWI76_RS05655 -0.8 -0.8 hypothetical protein compare
BWI76_RS09970 -0.8 -1.2 porin OmpA compare
BWI76_RS09870 -0.8 -4.2 aromatic amino acid aminotransferase compare
BWI76_RS15840 -0.8 -2.0 prophage protein compare
BWI76_RS22695 -0.8 -3.1 sulfate adenylyltransferase compare
BWI76_RS01115 -0.8 -2.0 dTDP-4-amino-4,6-dideoxygalactose transaminase compare
BWI76_RS13095 -0.8 -1.6 phenylacetate-CoA oxygenase subunit PaaB compare


Specific Phenotypes

For 3 genes in this experiment

For carbon source Sodium L-Lactate in Klebsiella michiganensis M5al

For carbon source Sodium L-Lactate across organisms