Experiment set5IT004 for Klebsiella michiganensis M5al

Compare to:

Sodium L-Lactate carbon source

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS01540 +1.2 3.1 thiamine biosynthesis protein ThiS compare
BWI76_RS17045 +1.2 2.1 hypothetical protein compare
BWI76_RS03045 +1.1 1.9 hypothetical protein compare
BWI76_RS07985 +1.1 1.7 fluoride ion transporter CrcB compare
BWI76_RS04305 +1.1 1.1 molecular chaperone DnaJ compare
BWI76_RS01995 +1.1 1.6 AraC family transcriptional regulator compare
BWI76_RS21245 +1.1 4.5 nitrogen regulatory protein P-II compare
BWI76_RS23305 +1.1 3.0 NADP(H)-dependent aldo-keto reductase compare
BWI76_RS13420 +1.0 2.8 ABC transporter permease compare
BWI76_RS08275 +1.0 1.5 LexA regulated protein compare
BWI76_RS25285 +1.0 1.3 HPr family phosphocarrier protein compare
BWI76_RS24575 +0.9 1.2 hypothetical protein compare
BWI76_RS27865 +0.9 2.3 hypothetical protein compare
BWI76_RS07475 +0.9 1.3 DNA-binding transcriptional regulator RamA compare
BWI76_RS17530 +0.9 3.4 hypothetical protein compare
BWI76_RS17350 +0.9 2.9 DNA-binding response regulator compare
BWI76_RS12485 +0.9 3.8 TyrR family transcriptional regulator compare
BWI76_RS06405 +0.8 1.7 2-dehydropantoate 2-reductase compare
BWI76_RS17200 +0.8 1.8 hypothetical protein compare
BWI76_RS13785 +0.8 2.1 ABC transporter permease compare
BWI76_RS20230 +0.8 0.6 hypothetical protein compare
BWI76_RS14390 +0.8 0.7 hypothetical protein compare
BWI76_RS13970 +0.8 1.7 ABC transporter compare
BWI76_RS17470 +0.8 1.6 MerR family transcriptional regulator compare
BWI76_RS01935 +0.8 1.3 thiamin phosphate synthase compare
BWI76_RS09335 +0.7 1.2 baseplate assembly protein W compare
BWI76_RS27635 +0.7 1.6 AraC family transcriptional regulator compare
BWI76_RS16015 +0.7 2.4 pheromone autoinducer 2 transporter compare
BWI76_RS20360 +0.7 1.1 cell division protein DedD compare
BWI76_RS20720 +0.7 1.2 hypothetical protein compare
BWI76_RS15150 +0.7 2.3 outer membrane efflux protein compare
BWI76_RS18240 +0.7 1.8 L-arabinose ABC transporter permease AraH compare
BWI76_RS24080 +0.7 1.0 DUF179 domain-containing protein compare
BWI76_RS15775 +0.7 2.0 replication protein compare
BWI76_RS15960 +0.7 2.2 LysR family transcriptional regulator compare
BWI76_RS19865 +0.7 2.0 ecotin compare
BWI76_RS13250 +0.7 1.0 cytochrome b561 compare
BWI76_RS12040 +0.7 1.1 hypothetical protein compare
BWI76_RS21375 +0.7 1.3 autonomous glycyl radical cofactor GrcA compare
BWI76_RS18780 +0.7 1.7 D-alanyl-D-alanine carboxypeptidase compare
BWI76_RS24240 +0.7 1.6 hypothetical protein compare
BWI76_RS16355 +0.7 1.9 electron transport complex subunit A compare
BWI76_RS07755 +0.6 1.9 isochorismatase compare
BWI76_RS14510 +0.6 2.2 MFS transporter compare
BWI76_RS24105 +0.6 2.7 resistance protein compare
BWI76_RS17570 +0.6 1.5 iron-sulfur-binding protein compare
BWI76_RS18550 +0.6 1.3 tRNA-Asn compare
BWI76_RS05355 +0.6 1.9 methionine ABC transporter substrate-binding protein MetQ compare
BWI76_RS10435 +0.6 1.3 suppressor for copper-sensitivity C compare
BWI76_RS23005 +0.6 2.0 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS17860 +0.6 1.5 YoaH family protein compare
BWI76_RS05235 +0.6 1.1 hypothetical protein compare
BWI76_RS11010 +0.6 1.9 30S ribosomal protein S5 alanine N-acetyltransferase compare
BWI76_RS25375 +0.6 1.8 hypothetical protein compare
BWI76_RS14610 +0.6 2.2 putative hydrolase compare
BWI76_RS26505 +0.6 1.8 nickel ABC transporter permease subunit NikB compare
BWI76_RS13415 +0.6 2.1 spermidine/putrescine ABC transporter permease compare
BWI76_RS09555 +0.6 2.2 pyruvate oxidase compare
BWI76_RS15015 +0.6 1.0 DUF2132 domain-containing protein compare
BWI76_RS01005 +0.6 1.5 CarD family transcriptional regulator compare
BWI76_RS05985 +0.6 2.0 branched-chain amino acid ABC transporter permease compare
BWI76_RS24270 +0.6 1.6 membrane protein compare
BWI76_RS10650 +0.6 2.2 PTS fructose-like transporter subunit EIIB compare
BWI76_RS20930 +0.6 1.3 arsenate reductase (glutaredoxin) compare
BWI76_RS25220 +0.6 2.0 outer membrane lipid asymmetry maintenance protein MlaD compare
BWI76_RS20145 +0.6 1.3 NADH-quinone oxidoreductase subunit K compare
BWI76_RS06550 +0.6 3.6 competence protein ComEA compare
BWI76_RS26660 +0.6 3.1 transcription elongation factor GreB compare
BWI76_RS09560 +0.6 1.4 DoxX family membrane protein compare
BWI76_RS19195 +0.6 2.4 nickel ABC transporter permease compare
BWI76_RS04580 +0.6 2.3 L-ribulose-5-phosphate 4-epimerase compare
BWI76_RS01335 +0.6 2.7 DNase TatD compare
BWI76_RS07640 +0.6 1.3 short chain dehydrogenase compare
BWI76_RS11705 +0.5 3.1 hypothetical protein compare
BWI76_RS09935 +0.5 1.6 paraquat-inducible membrane protein A compare
BWI76_RS20290 +0.5 1.3 thiol:disulfide oxidoreductase compare
BWI76_RS00740 +0.5 1.6 ribonuclease E activity regulator RraA compare
BWI76_RS00720 +0.5 1.4 DNA-binding response regulator compare
BWI76_RS13360 +0.5 1.6 benzoate transporter compare
BWI76_RS19450 +0.5 2.3 hypothetical protein compare
BWI76_RS06075 +0.5 1.9 taurine transporter subunit compare
BWI76_RS20940 +0.5 1.8 uracil/xanthine transporter compare
BWI76_RS15260 +0.5 1.2 hypothetical protein compare
BWI76_RS12205 +0.5 2.4 hypothetical protein compare
BWI76_RS06335 +0.5 1.1 nucleoside-specific channel-forming protein Tsx compare
BWI76_RS01330 +0.5 1.7 twin-arginine translocase subunit TatC compare
BWI76_RS27780 +0.5 1.2 hypothetical protein compare
BWI76_RS05465 +0.5 0.8 amidohydrolase compare
BWI76_RS15950 +0.5 1.1 dethiobiotin synthase compare
BWI76_RS01675 +0.5 1.8 putative cytoplasmic protein compare
BWI76_RS23015 +0.5 1.0 cobalt transporter ATP-binding subunit compare
BWI76_RS20925 +0.5 2.1 peptidase M48 compare
BWI76_RS22090 +0.5 1.6 transcriptional regulator compare
BWI76_RS16900 +0.5 0.8 4-hydroxy-2-oxovalerate aldolase compare
BWI76_RS22470 +0.5 1.6 transporter permease compare
BWI76_RS24885 +0.5 0.6 PTS galactitol transporter subunit IIB compare
BWI76_RS11635 +0.5 1.1 ABC transporter compare
BWI76_RS11675 +0.5 1.0 arginine N-succinyltransferase compare
BWI76_RS01835 +0.5 1.9 chemotaxis protein CheW compare
BWI76_RS00025 +0.5 0.7 hypothetical protein compare
BWI76_RS07520 +0.5 3.3 ABC transporter substrate-binding protein compare
BWI76_RS23860 +0.5 1.3 protein disulfide oxidoreductase compare
BWI76_RS10950 +0.5 1.8 MFS transporter compare
BWI76_RS14415 +0.5 1.4 transcriptional regulator, TetR family protein compare
BWI76_RS09305 +0.5 1.2 hypothetical protein compare
BWI76_RS06910 +0.5 0.9 transcriptional regulator compare
BWI76_RS16675 +0.5 0.8 ABC transporter compare
BWI76_RS16210 +0.5 1.2 hypothetical protein compare
BWI76_RS04560 +0.5 1.1 holo-ACP synthase CitX compare
BWI76_RS07895 +0.5 1.5 sugar ABC transporter ATPase compare
BWI76_RS12860 +0.5 1.5 hypothetical protein compare
BWI76_RS14755 +0.5 1.2 SIS domain-containing protein compare
BWI76_RS13515 +0.5 1.9 amino acid permease compare
BWI76_RS24630 +0.5 2.0 putrescine aminotransferase compare
BWI76_RS02725 +0.5 0.7 HxlR family transcriptional regulator compare
BWI76_RS18090 +0.5 1.9 phosphoribosylglycinamide formyltransferase 2 compare
BWI76_RS17915 +0.5 2.2 membrane protein compare
BWI76_RS12870 +0.5 0.8 putative phytanoyl-CoA dioxygenase compare
BWI76_RS20795 +0.5 0.7 ethanolamine catabolic microcompartment shell protein EutN compare
BWI76_RS24525 +0.5 1.8 urease accessory protein UreG compare
BWI76_RS23125 +0.5 0.5 propanediol dehydratase small subunit compare
BWI76_RS26095 +0.5 0.5 shikimate kinase compare
BWI76_RS17185 +0.5 2.1 fructosamine kinase family protein compare
BWI76_RS12045 +0.5 1.5 hypothetical protein compare
BWI76_RS23080 +0.5 2.8 precorrin-8X methylmutase compare
BWI76_RS23060 +0.5 3.0 cobalt-precorrin-4 C(11)-methyltransferase compare
BWI76_RS12470 +0.5 0.9 thiosulfate sulfurtransferase PspE compare
BWI76_RS09830 +0.5 1.1 tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM compare
BWI76_RS19575 +0.5 1.5 maleylacetoacetate isomerase compare
BWI76_RS03870 +0.5 1.5 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase compare
BWI76_RS07595 +0.5 0.8 putative oxidoreductase compare
BWI76_RS23690 +0.5 1.1 putative glyoxalase/bleomycin resistance protein/dioxygenase compare
BWI76_RS01585 +0.5 2.1 transcriptional regulator compare
BWI76_RS20605 +0.5 2.1 purine-nucleoside phosphorylase compare
BWI76_RS23900 +0.5 1.8 hypothetical protein compare
BWI76_RS27105 +0.4 2.9 3-keto-L-gulonate-6-phosphate decarboxylase compare
BWI76_RS13280 +0.4 3.0 LysR family transcriptional regulator compare
BWI76_RS03180 +0.4 1.0 phage transcriptional regulator, AlpA compare
BWI76_RS25655 +0.4 1.5 DNA topoisomerase type IA zn finger domain-containing protein compare
BWI76_RS24380 +0.4 1.5 esterase YqiA compare
BWI76_RS11520 +0.4 0.6 hypothetical protein compare
BWI76_RS23320 +0.4 0.8 hypothetical protein compare
BWI76_RS12620 +0.4 1.8 2-nitropropane dioxygenase compare
BWI76_RS06250 +0.4 1.0 alpha-glycosidase compare
BWI76_RS25545 +0.4 0.8 hypothetical protein compare
BWI76_RS11255 +0.4 0.7 putrescine/spermidine ABC transporter ATP-binding protein compare
BWI76_RS09690 +0.4 1.1 dimethyl sulfoxide reductase compare
BWI76_RS01560 +0.4 1.5 Rsd/AlgQ family anti-sigma factor compare
BWI76_RS16270 +0.4 1.6 fumarate hydratase, class II compare
BWI76_RS12565 +0.4 2.5 SAM-dependent methyltransferase compare
BWI76_RS01000 +0.4 1.4 peptidyl-prolyl cis-trans isomerase compare
BWI76_RS13720 +0.4 1.3 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase compare
BWI76_RS26915 +0.4 2.6 hypothetical protein compare
BWI76_RS05785 +0.4 1.6 CI repressor compare
BWI76_RS25035 +0.4 1.9 malonate transporter subunit MadM compare
BWI76_RS01840 +0.4 1.7 maltose ABC transporter, ATPase component (MalK) (from data) compare
BWI76_RS10500 +0.4 1.4 flavoprotein monooxygenase compare
BWI76_RS13215 +0.4 0.8 type I glyceraldehyde-3-phosphate dehydrogenase compare
BWI76_RS09130 +0.4 1.8 biofilm formation regulatory protein BssR compare
BWI76_RS03515 +0.4 1.7 hypothetical protein compare
BWI76_RS03905 +0.4 1.6 2-oxo-3-deoxygalactonate kinase compare
BWI76_RS20730 +0.4 1.0 hypothetical protein compare
BWI76_RS26365 +0.4 2.0 branched chain amino acid ABC transporter substrate-binding protein compare
BWI76_RS06110 +0.4 1.7 hypothetical protein compare
BWI76_RS13085 +0.4 1.9 bifunctional oxepin-CoA hydrolase/3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase compare
BWI76_RS07885 +0.4 1.3 sugar ABC transporter permease compare
BWI76_RS17380 +0.4 1.8 nitrate transporter component compare
BWI76_RS13755 +0.4 1.2 hypothetical protein compare
BWI76_RS07530 +0.4 1.2 binding-protein-dependent transport system inner membrane protein compare
BWI76_RS18235 +0.4 1.1 trehalose-phosphatase compare
BWI76_RS03890 +0.4 1.9 hypothetical protein compare
BWI76_RS19790 +0.4 2.5 putative binding-protein-dependent transporter compare
BWI76_RS02875 +0.4 2.4 membrane protein compare
BWI76_RS06470 +0.4 1.6 hypothetical protein compare
BWI76_RS21740 +0.4 1.8 transcriptional regulator, LysR family protein compare
BWI76_RS11690 +0.4 2.5 succinylglutamate desuccinylase compare
BWI76_RS22815 +0.4 2.8 hybrid sensor histidine kinase/response regulator compare
BWI76_RS25240 +0.4 1.2 D-arabinose 5-phosphate isomerase compare
BWI76_RS25300 +0.4 1.4 hybrid sensor histidine kinase/response regulator compare
BWI76_RS19615 +0.4 1.7 vancomycin high temperature exclusion protein compare
BWI76_RS02860 +0.4 1.0 glycine dehydrogenase compare
BWI76_RS18060 +0.4 2.0 hypothetical protein compare
BWI76_RS10755 +0.4 0.8 pyrimidine utilization flavin reductase protein F compare
BWI76_RS17420 +0.4 1.8 hypothetical protein compare
BWI76_RS23140 +0.4 0.7 carboxysome shell protein compare
BWI76_RS26280 +0.4 1.8 hypothetical protein compare
BWI76_RS18555 +0.4 2.5 MATE family multidrug exporter compare
BWI76_RS24910 +0.4 2.2 rRNA (cytidine-2'-O-)-methyltransferase compare
BWI76_RS11125 +0.4 0.7 metal-dependent hydrolase compare
BWI76_RS13955 +0.4 1.2 hypothetical protein compare
BWI76_RS13395 +0.4 2.2 cytochrome D ubiquinol oxidase subunit I compare
BWI76_RS20055 +0.4 2.6 2-succinylbenzoate-CoA ligase compare
BWI76_RS20900 +0.4 0.7 outer membrane protein assembly factor BamC compare
BWI76_RS05735 +0.4 2.4 transcriptional regulator compare
BWI76_RS01810 +0.4 2.3 N-acetyltransferase compare
BWI76_RS02570 +0.4 1.2 transcriptional regulator compare
BWI76_RS22850 +0.4 0.9 tRNA pseudouridine synthase TruC compare
BWI76_RS15660 +0.4 0.5 hypothetical protein compare
BWI76_RS26020 +0.4 1.6 peptidylprolyl isomerase A compare
BWI76_RS22190 +0.4 2.4 hypothetical protein compare


Specific Phenotypes

For 3 genes in this experiment

For carbon source Sodium L-Lactate in Klebsiella michiganensis M5al

For carbon source Sodium L-Lactate across organisms