Experiment set5IT003 for Methanococcus maripaludis S2

Compare to:

Formate with Nalidixic acid 6.25 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS01175 -4.1 -7.0 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS08300 -3.5 -3.3 metal-sulfur cluster assembly factor compare
MMP_RS06700 -3.3 -18.9 hypothetical protein compare
MMP_RS01020 -3.2 -2.7 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS06685 -3.2 -17.4 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS06680 -3.1 -20.0 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS05920 -3.0 -1.8 50S ribosomal protein L37e compare
MMP_RS06355 -3.0 -5.4 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS05515 -2.9 -11.5 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS07635 -2.9 -11.6 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS08820 -2.8 -9.5 hypothetical protein compare
MMP_RS03315 -2.8 -3.0 ferrous iron transport protein A compare
MMP_RS02010 -2.7 -14.7 PHP domain-containing protein compare
MMP_RS07545 -2.7 -2.6 HTH domain-containing protein compare
MMP_RS03015 -2.6 -14.0 GTP 3' 8-cyclase MoaA compare
MMP_RS02195 -2.6 -9.7 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS06345 -2.5 -16.1 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS06350 -2.5 -9.1 HesA/MoeB/ThiF family protein compare
MMP_RS02280 -2.4 -2.3 DUF211 domain-containing protein compare
MMP_RS01005 -2.3 -3.1 riboflavin synthase compare
MMP_RS01755 -2.3 -3.0 DUF2097 domain-containing protein compare
MMP_RS06720 -2.2 -12.5 response regulator transcription factor compare
MMP_RS00895 -2.1 -8.9 hypothetical protein compare
MMP_RS03025 -2.1 -8.4 molybdenum cofactor guanylyltransferase compare
MMP_RS06715 -2.1 -16.2 cache domain-containing protein compare
MMP_RS01265 -2.1 -4.1 hypothetical protein compare
MMP_RS00300 -2.1 -1.4 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS04685 -2.0 -5.9 DUF126 domain-containing protein compare
MMP_RS06295 -2.0 -7.9 methanogenesis marker 14 protein compare
MMP_RS04780 -2.0 -3.9 ribonuclease P compare
MMP_RS01500 -2.0 -3.8 CBS domain-containing protein compare
MMP_RS08210 -1.9 -3.1 phosphatidylglycerophosphatase A compare
MMP_RS07445 -1.9 -7.5 helix-turn-helix domain-containing protein compare
MMP_RS06630 -1.9 -2.1 UPF0058 family protein compare
MMP_RS01220 -1.8 -9.3 hypothetical protein compare
MMP_RS08745 -1.8 -9.7 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS07730 -1.8 -2.6 pyruvate synthase subunit beta compare
MMP_RS07845 -1.8 -4.8 LL-diaminopimelate aminotransferase compare
MMP_RS08460 -1.7 -3.0 proteasome-activating nucleotidase compare
MMP_RS03205 -1.7 -2.4 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS08635 -1.7 -3.7 UbiA family prenyltransferase compare
MMP_RS00115 -1.7 -12.6 radical SAM protein compare
MMP_RS06400 -1.7 -3.2 4Fe-4S binding protein compare
MMP_RS00515 -1.7 -2.1 DUF655 domain-containing protein compare
MMP_RS08720 -1.7 -1.8 4Fe-4S binding protein compare
MMP_RS00110 -1.7 -3.8 hypothetical protein compare
MMP_RS00685 -1.7 -6.7 2-phospho-L-lactate guanylyltransferase compare
MMP_RS06230 -1.7 -3.9 helix-turn-helix domain-containing protein compare
MMP_RS05550 -1.6 -1.5 cation:proton antiporter compare
MMP_RS06705 -1.6 -9.0 formate/nitrite transporter family protein compare
MMP_RS09020 -1.6 -2.9 hypothetical protein compare
MMP_RS07575 -1.6 -7.7 RNA ligase partner protein compare
MMP_RS02240 -1.6 -5.6 methanogenesis marker 7 protein compare
MMP_RS04955 -1.6 -5.6 DNA topoisomerase I compare
MMP_RS04585 -1.6 -8.5 AIR synthase related protein compare
MMP_RS07735 -1.6 -1.7 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS06285 -1.6 -3.4 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS06020 -1.5 -6.1 archaeoflavoprotein AfpA compare
MMP_RS07600 -1.5 -4.6 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS01830 -1.5 -3.0 tRNA-Val compare
MMP_RS03435 -1.5 -2.5 ketol-acid reductoisomerase compare
MMP_RS03035 -1.5 -4.2 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS05540 -1.5 -3.8 hypothetical protein compare
MMP_RS07525 -1.5 -8.5 4Fe-4S binding protein compare
MMP_RS02800 -1.4 -6.5 nucleotidyltransferase domain-containing protein compare
MMP_RS03475 -1.4 -1.0 hypothetical protein compare
MMP_RS07005 -1.4 -1.0 4Fe-4S binding protein compare
MMP_RS05555 -1.4 -3.0 DUF4040 domain-containing protein compare
MMP_RS06270 -1.4 -5.3 TIGR00300 family protein compare
MMP_RS06840 -1.4 -2.0 DNA-directed RNA polymerase subunit N compare
MMP_RS02135 -1.4 -5.9 DUF5612 domain-containing protein compare
MMP_RS02235 -1.4 -10.7 CBS domain-containing protein compare
MMP_RS06865 -1.4 -2.0 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS07200 -1.4 -6.4 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS04890 -1.3 -1.3 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS06120 -1.3 -3.1 UPF0147 family protein compare
MMP_RS01225 -1.3 -5.4 DUF5379 domain-containing protein compare
MMP_RS04875 -1.3 -5.3 energy-converting hydrogenase B subunit P compare
MMP_RS01610 -1.3 -5.5 hypothetical protein compare
MMP_RS06105 -1.3 -7.1 hydrogenase maturation peptidase HycI compare
MMP_RS08435 -1.3 -1.7 Era-like GTP-binding protein compare
MMP_RS06340 -1.3 -8.2 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS05875 -1.2 -6.2 hydroxyethylthiazole kinase compare
MMP_RS03640 -1.2 -4.1 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS03580 -1.2 -3.1 signal recognition particle-docking protein FtsY compare
MMP_RS07420 -1.2 -4.9 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS06110 -1.2 -4.1 ATP-dependent protease LonB compare
MMP_RS04870 -1.2 -5.0 TIGR02253 family HAD-type hydrolase compare
MMP_RS04775 -1.2 -3.4 adenosylhomocysteinase compare
MMP_RS02875 -1.2 -8.0 chorismate pyruvate-lyase family protein compare
MMP_RS06730 -1.2 -1.6 phosphopantothenate/pantothenate synthetase compare
MMP_RS04500 -1.2 -10.1 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS00295 -1.2 -3.6 gamma carbonic anhydrase family protein compare
MMP_RS06895 -1.2 -2.6 selenocysteine-specific translation elongation factor compare
MMP_RS04605 -1.2 -4.0 cobalt ECF transporter T component CbiQ compare
MMP_RS03400 -1.1 -3.1 archease compare
MMP_RS02900 -1.1 -0.8 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS06175 -1.1 -6.8 winged helix-turn-helix transcriptional regulator compare
MMP_RS01795 -1.1 -2.0 methanogenesis marker 6 protein compare
MMP_RS05815 -1.1 -2.9 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS07190 -1.1 -6.7 chromosome segregation protein SMC compare
MMP_RS02355 -1.1 -4.3 30S ribosomal protein S27ae compare
MMP_RS01700 -1.1 -1.5 dihydroxy-acid dehydratase compare
MMP_RS03600 -1.1 -2.7 triose-phosphate isomerase compare
MMP_RS07750 -1.0 -3.6 DUF357 domain-containing protein compare
MMP_RS05430 -1.0 -4.7 TIGR00288 family NYN domain-containing protein compare
MMP_RS06885 -1.0 -2.2 50S ribosome-binding GTPase compare
MMP_RS07790 -1.0 -8.1 segregation/condensation protein A compare
MMP_RS06925 -1.0 -2.1 ribonuclease VapC4 compare
MMP_RS07580 -1.0 -2.4 DUF356 domain-containing protein compare
MMP_RS02145 -1.0 -5.6 winged helix-turn-helix transcriptional regulator compare
MMP_RS00695 -1.0 -0.7 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS07380 -1.0 -2.1 transcription elongation factor Spt5 compare
MMP_RS01800 -1.0 -4.1 TIGR00303 family protein compare
MMP_RS01385 -1.0 -0.9 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS08165 -0.9 -2.2 phosphoglycerate dehydrogenase compare
MMP_RS06625 -0.9 -2.4 DNA primase compare
MMP_RS06215 -0.9 -3.6 30S ribosomal protein S6e compare
MMP_RS00915 -0.9 -4.2 DUF116 domain-containing protein compare
MMP_RS00720 -0.9 -6.1 metal-dependent hydrolase compare
MMP_RS03960 -0.9 -1.0 hypothetical protein compare
MMP_RS02190 -0.9 -2.1 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS08320 -0.9 -5.3 molybdopterin molybdotransferase MoeA compare
MMP_RS00320 -0.8 -2.5 class I SAM-dependent methyltransferase compare
MMP_RS06370 -0.8 -3.6 biotin synthase BioB compare
MMP_RS08100 -0.8 -5.4 8-amino-7-oxononanoate synthase compare
MMP_RS05265 -0.8 -2.1 2-isopropylmalate synthase compare
MMP_RS07755 -0.8 -1.6 DUF555 domain-containing protein compare
MMP_RS00305 -0.8 -1.7 phosphoribosyl-ATP diphosphatase compare
MMP_RS07195 -0.8 -5.3 M20 family metallo-hydrolase compare
MMP_RS01985 -0.8 -4.8 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS05315 -0.8 -2.2 hypothetical protein compare
MMP_RS08790 -0.8 -1.8 translation initiation factor IF-2 subunit alpha compare
MMP_RS07090 -0.8 -4.6 tRNA (adenine-N1)-methyltransferase compare
MMP_RS03155 -0.7 -4.5 precorrin-6A reductase compare
MMP_RS08725 -0.7 -0.8 Ni/Fe hydrogenase subunit alpha compare
MMP_RS03555 -0.7 -5.3 transcriptional regulator compare
MMP_RS08715 -0.7 -1.5 formylmethanofuran dehydrogenase subunit B compare
MMP_RS01180 -0.7 -0.9 XTP/dITP diphosphatase compare
MMP_RS05445 -0.7 -4.8 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS00060 -0.7 -1.4 3-dehydroquinate synthase II compare
MMP_RS07955 -0.7 -3.9 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS04620 -0.7 -4.9 cobalt transporter CbiM compare
MMP_RS01195 -0.7 -1.6 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS01325 -0.7 -1.7 dihydroneopterin aldolase family protein compare
MMP_RS00900 -0.7 -2.4 50S ribosomal protein L39e compare
MMP_RS05845 -0.7 -1.2 tRNA-intron lyase compare
MMP_RS05245 -0.7 -4.8 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS02885 -0.7 -5.6 molybdopterin biosynthesis protein compare
MMP_RS05925 -0.7 -2.5 small nuclear ribonucleoprotein compare
MMP_RS01250 -0.7 -2.5 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS02130 -0.7 -3.1 zinc metalloprotease HtpX compare
MMP_RS03095 -0.6 -4.0 diphthine synthase compare
MMP_RS00750 -0.6 -2.2 fumarate hydratase compare
MMP_RS06200 -0.6 -4.3 M24 family metallopeptidase compare
MMP_RS07645 -0.6 -3.3 aldehyde dehydrogenase family protein compare
MMP_RS01600 -0.6 -1.5 50S ribosomal protein L15e compare
MMP_RS00120 -0.6 -2.8 LysR family transcriptional regulator compare
MMP_RS03445 -0.6 -1.1 methanogenesis marker 17 protein compare
MMP_RS04615 -0.6 -1.9 PDGLE domain-containing protein compare
MMP_RS08940 -0.6 -1.3 MetS family NSS transporter small subunit compare
MMP_RS07630 -0.6 -1.6 ATP-binding cassette domain-containing protein compare
MMP_RS04720 -0.6 -1.8 DedA family protein compare
MMP_RS03120 -0.6 -2.7 hypothetical protein compare
MMP_RS08105 -0.6 -3.6 6-carboxyhexanoate--CoA ligase compare
MMP_RS02170 -0.6 -2.9 CBS domain-containing protein compare
MMP_RS05295 -0.6 -4.6 minichromosome maintenance protein MCM compare
MMP_RS08095 -0.6 -3.3 dethiobiotin synthase compare
MMP_RS07425 -0.6 -2.8 GTP-binding protein compare
MMP_RS01840 -0.6 -3.3 TIGR00289 family protein compare
MMP_RS07365 -0.6 -4.5 2-phosphoglycerate kinase compare
MMP_RS00620 -0.6 -4.2 4Fe-4S binding protein compare
MMP_RS08330 -0.6 -3.1 NADH-quinone oxidoreductase subunit H compare
MMP_RS08600 -0.6 -1.7 flagellar protein D compare
MMP_RS07765 -0.6 -3.8 sodium:alanine symporter family protein compare
MMP_RS00985 -0.6 -3.1 CDC48 family AAA ATPase compare
MMP_RS00520 -0.6 -0.8 RNA polymerase Rpb4 family protein compare
MMP_RS05095 -0.6 -4.3 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS06275 -0.6 -3.9 ATP-dependent DNA helicase compare
MMP_RS00050 -0.6 -3.6 AarF/UbiB family protein compare
MMP_RS07535 -0.5 -3.7 4Fe-4S binding protein compare
MMP_RS08915 -0.5 -1.1 2 5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase compare
MMP_RS02345 -0.5 -1.7 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS08650 -0.5 -2.1 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS01725 -0.5 -2.4 class I SAM-dependent methyltransferase family protein compare
MMP_RS07605 -0.5 -2.4 diadenylate cyclase compare
MMP_RS04125 -0.5 -2.6 TetR/AcrR family transcriptional regulator compare
MMP_RS02165 -0.5 -2.9 tRNA-dihydrouridine synthase compare
MMP_RS08200 -0.5 -4.6 archaeosine synthase subunit alpha compare
MMP_RS05060 -0.5 -4.1 AAA family ATPase compare
MMP_RS05510 -0.5 -3.6 Rrf2 family transcriptional regulator compare
MMP_RS00315 -0.5 -2.7 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS03305 -0.5 -3.8 winged helix-turn-helix domain-containing protein compare
MMP_RS07685 -0.5 -2.3 TIGR01212 family radical SAM protein compare
MMP_RS04710 -0.5 -1.0 hypothetical protein compare
MMP_RS03385 -0.5 -0.9 cation diffusion facilitator family transporter compare
MMP_RS07700 -0.5 -2.9 DUF1188 domain-containing protein compare
MMP_RS02340 -0.5 -0.8 DNA-directed RNA polymerase subunit E'' compare
MMP_RS04015 -0.5 -1.0 hypothetical protein compare
MMP_RS04360 -0.5 -2.5 hypothetical protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments

For nutrient t1 Nalidixic acid sodium salt across organisms