Experiment set5IT003 for Methanococcus maripaludis S2

Compare to:

Formate with Nalidixic acid 6.25 mM

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS07820 +0.7 3.7 UPF0104 family protein compare
MMP_RS02790 +0.6 1.5 class III signal peptide-containing protein compare
MMP_RS04520 +0.6 2.8 nucleoside deaminase compare
MMP_RS03450 +0.6 1.9 glycine synthesis protein GlyXS (from data) compare
MMP_RS03340 +0.6 1.0 ABC transporter ATP-binding protein compare
MMP_RS00825 +0.6 3.1 fumarylacetoacetate hydrolase family protein compare
MMP_RS02470 +0.6 1.8 helix-turn-helix transcriptional regulator compare
MMP_RS08705 +0.5 3.1 sulfopyruvate decarboxylase subunit beta compare
MMP_RS01545 +0.5 0.8 CBS domain-containing protein compare
MMP_RS01570 +0.5 1.5 hypothetical protein compare
MMP_RS07125 +0.5 1.9 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS00945 +0.5 1.1 PadR family transcriptional regulator compare
MMP_RS09025 +0.5 1.1 hypothetical protein compare
MMP_RS00740 +0.5 1.5 cyclase family protein compare
MMP_RS07120 +0.5 3.8 coenzyme F420 hydrogenase subunit alpha compare
MMP_RS02175 +0.4 0.8 DUF1611 domain-containing protein compare
MMP_RS08440 +0.4 1.2 cell division protein SepF compare
MMP_RS06575 +0.4 2.6 fluoride efflux transporter CrcB compare
MMP_RS07130 +0.4 3.1 coenzyme F420 hydrogenase subunit gamma compare
MMP_RS08215 +0.4 2.0 DUF483 domain-containing protein compare
MMP_RS01370 +0.4 3.1 acetate--CoA ligase family protein compare
MMP_RS06555 +0.4 2.0 cupin domain-containing protein compare
MMP_RS01435 +0.4 1.9 DMT family transporter compare
MMP_RS05975 +0.4 1.2 hypothetical protein compare
MMP_RS05990 +0.4 2.0 DsrE family protein compare
MMP_RS08310 +0.4 1.4 TMEM165/GDT1 family protein compare
MMP_RS06000 +0.4 1.7 divalent-cation tolerance protein CutA compare
MMP_RS03465 +0.4 0.8 adenine phosphoribosyltransferase compare
MMP_RS06545 +0.4 2.1 ferredoxin family protein compare
MMP_RS08615 +0.3 1.4 flagellar protein G compare
MMP_RS01540 +0.3 1.7 DUF504 domain-containing protein compare
MMP_RS02290 +0.3 1.9 MBL fold metallo-hydrolase compare
MMP_RS07135 +0.3 2.6 coenzyme F420 hydrogenase subunit beta compare
MMP_RS02475 +0.3 1.5 hypothetical protein compare
MMP_RS05640 +0.3 1.6 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS02085 +0.3 1.9 inosine/xanthosine triphosphatase compare
MMP_RS07095 +0.3 1.7 PspC domain-containing protein compare
MMP_RS07875 +0.3 1.4 hypothetical protein compare
MMP_RS04790 +0.3 2.4 4-hydroxy-tetrahydrodipicolinate reductase compare
MMP_RS04740 +0.3 1.5 DUF473 domain-containing protein compare
MMP_RS06325 +0.3 0.9 hypothetical protein compare
MMP_RS08370 +0.3 0.4 cation:proton antiporter subunit C compare
MMP_RS05355 +0.3 0.6 hypothetical protein compare
MMP_RS03890 +0.3 1.7 DUF2540 domain-containing protein compare
MMP_RS08315 +0.3 1.4 S-methyl-5-thioribose-1-phosphate isomerase compare
MMP_RS06480 +0.3 2.5 ABC transporter substrate-binding protein compare
MMP_RS05795 +0.3 1.4 redox-regulated ATPase YchF compare
MMP_RS06530 +0.3 1.9 bifunctional hexulose-6-phosphate synthase/ribonuclease regulator compare
MMP_RS05940 +0.3 2.5 corrinoid protein compare
MMP_RS03440 +0.3 0.7 MoaD/ThiS family protein compare
MMP_RS01675 +0.3 1.0 hypothetical protein compare
MMP_RS03215 +0.3 2.4 MBL fold metallo-hydrolase compare
MMP_RS01260 +0.3 1.5 HDIG domain-containing protein compare
MMP_RS03405 +0.3 2.0 RNA 3'-terminal phosphate cyclase compare
MMP_RS04265 +0.3 1.4 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS03820 +0.3 1.8 EamA family transporter compare
MMP_RS08595 +0.3 0.6 flagellar protein C compare
MMP_RS07680 +0.3 1.4 DUF366 family protein compare
MMP_RS07895 +0.3 1.6 cytochrome c compare
MMP_RS01165 +0.3 1.4 DUF434 domain-containing protein compare
MMP_RS03910 +0.3 1.1 hypothetical protein compare
MMP_RS01940 +0.3 1.2 MoxR family ATPase compare
MMP_RS02480 +0.3 1.1 hypothetical protein compare
MMP_RS02815 +0.3 1.1 hypothetical protein compare
MMP_RS01525 +0.3 0.9 nucleoside-diphosphate kinase compare
MMP_RS08580 +0.3 0.9 flagellin compare
MMP_RS07345 +0.2 1.5 glycine synthesis protein GlyXL (from data) compare
MMP_RS05175 +0.2 1.4 hypothetical protein compare
MMP_RS06155 +0.2 1.0 DUF4186 domain-containing protein compare
MMP_RS02490 +0.2 1.2 hypothetical protein compare
MMP_RS08470 +0.2 1.9 ATP-binding cassette domain-containing protein compare
MMP_RS07115 +0.2 1.8 MBL fold metallo-hydrolase compare
MMP_RS01930 +0.2 2.0 hypothetical protein compare
MMP_RS05250 +0.2 0.6 NFYB/HAP3 family transcription factor subunit compare
MMP_RS08760 +0.2 1.4 hypothetical protein compare
MMP_RS06900 +0.2 1.1 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS08155 +0.2 1.7 hypothetical protein compare
MMP_RS04165 +0.2 1.9 TetR/AcrR family transcriptional regulator compare
MMP_RS03150 +0.2 2.0 phosphoglycerate mutase compare
MMP_RS00630 +0.2 1.3 ECF transporter S component compare
MMP_RS09035 +0.2 0.9 hypothetical protein compare
MMP_RS02725 +0.2 1.5 molybdate ABC transporter permease subunit compare
MMP_RS07725 +0.2 0.8 4Fe-4S dicluster domain-containing protein compare
MMP_RS04195 +0.2 1.2 flavodoxin compare
MMP_RS03800 +0.2 1.2 hypothetical protein compare
MMP_RS07150 +0.2 1.5 MTH895/ArsE family thioredoxin-like protein compare
MMP_RS02310 +0.2 0.7 RimK-like ATPgrasp N-terminal domain-containing protein compare
MMP_RS00665 +0.2 1.0 hypothetical protein compare
MMP_RS01420 +0.2 0.6 hypothetical protein compare
MMP_RS07815 +0.2 0.6 DUF2120 domain-containing protein compare
MMP_RS03130 +0.2 1.3 hypothetical protein compare
MMP_RS00800 +0.2 1.8 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS08850 +0.2 2.0 hypothetical protein compare
MMP_RS00185 +0.2 1.9 potassium channel protein compare
MMP_RS08995 +0.2 0.6 hypothetical protein compare
MMP_RS00530 +0.2 1.2 tRNA pseudouridine(54/55) synthase Pus10 compare
MMP_RS08930 +0.2 0.7 hypothetical protein compare
MMP_RS08890 +0.2 1.7 glycosyltransferase family 4 protein compare
MMP_RS01785 +0.2 1.5 hypothetical protein compare
MMP_RS01440 +0.2 1.4 NAAT family transporter compare
MMP_RS05675 +0.2 0.7 phosphate ABC transporter ATP-binding protein PstB compare
MMP_RS01745 +0.2 1.3 AMP phosphorylase compare
MMP_RS06445 +0.2 1.2 DUF89 domain-containing protein compare
MMP_RS06540 +0.2 0.8 3-methyl-2-oxobutanoate dehydrogenase subunit VorB compare
MMP_RS09050 +0.2 0.7 CAP domain-containing protein compare
MMP_RS04985 +0.2 0.6 DUF2180 family protein compare
MMP_RS05900 +0.2 1.3 tetratricopeptide repeat protein compare
MMP_RS05530 +0.2 1.4 signal peptide peptidase SppA compare
MMP_RS01470 +0.2 0.6 ATP-binding cassette domain-containing protein compare
MMP_RS06435 +0.2 1.4 CBS domain-containing protein compare
MMP_RS06140 +0.2 0.6 radical SAM protein compare
MMP_RS03235 +0.2 0.8 tRNA pseudouridine(13) synthase TruD compare
MMP_RS06460 +0.2 0.8 pyrimidine dimer DNA glycosylase/endonuclease V compare
MMP_RS07590 +0.2 1.5 hypothetical protein compare
MMP_RS08670 +0.2 1.4 metallophosphoesterase compare
MMP_RS07925 +0.2 1.1 haloacid dehalogenase compare
MMP_RS08160 +0.2 1.2 EamA family transporter compare
MMP_RS01935 +0.2 1.4 DUF58 domain-containing protein compare
MMP_RS01210 +0.2 1.3 sodium:solute symporter compare
MMP_RS08625 +0.2 1.4 type II/IV secretion system ATPase subunit compare
MMP_RS00145 +0.2 1.3 ATP-dependent Clp protease proteolytic subunit compare
MMP_RS03350 +0.2 0.9 winged helix-turn-helix domain-containing protein compare
MMP_RS06875 +0.2 1.1 FAD-dependent oxidoreductase compare
MMP_RS00445 +0.2 1.4 7-carboxy-7-deazaguanine synthase QueE compare
MMP_RS04315 +0.2 1.3 corrinoid protein compare
MMP_RS06735 +0.2 1.2 class I SAM-dependent rRNA methyltransferase compare
MMP_RS04250 +0.2 1.4 PC4/YdbC family ssDNA-binding protein compare
MMP_RS03615 +0.2 1.3 4Fe-4S binding protein compare
MMP_RS01945 +0.2 1.3 DUF4350 domain-containing protein compare
MMP_RS08245 +0.2 1.3 DUF4013 domain-containing protein compare
MMP_RS03520 +0.2 0.7 YwbE family protein compare
MMP_RS06745 +0.2 1.0 DUF2119 domain-containing protein compare
MMP_RS01455 +0.2 1.3 nickel pincer cofactor biosynthesis protein LarC compare
MMP_RS07155 +0.2 1.1 MFS transporter compare
MMP_RS01090 +0.2 1.3 ABC transporter substrate-binding protein compare
MMP_RS08385 +0.2 1.4 ABC transporter substrate-binding protein compare
MMP_RS02730 +0.2 1.3 ModD protein compare
MMP_RS00395 +0.2 0.5 MGMT family protein compare
MMP_RS00660 +0.2 1.3 alkaline phosphatase family protein compare
MMP_RS05980 +0.2 1.3 ferritin compare
MMP_RS02360 +0.2 0.9 hypothetical protein compare
MMP_RS00335 +0.2 0.7 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMP_RS08280 +0.2 0.8 proteasome assembly chaperone family protein compare
MMP_RS06490 +0.2 0.9 hypothetical protein compare
MMP_RS08500 +0.2 0.9 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMP_RS01065 +0.2 1.4 alpha/beta hydrolase compare
MMP_RS05665 +0.2 0.9 phosphate ABC transporter permease subunit PstC compare
MMP_RS08485 +0.2 1.0 tungstate ABC transporter substrate-binding protein WtpA compare
MMP_RS01465 +0.2 0.8 hypothetical protein compare
MMP_RS08090 +0.2 0.8 hypothetical protein compare
MMP_RS06170 +0.2 1.2 ABC transporter ATP-binding protein compare
MMP_RS01950 +0.2 1.2 hypothetical protein compare
MMP_RS02910 +0.2 1.2 ABC transporter substrate-binding protein compare
MMP_RS02770 +0.2 0.6 hypothetical protein compare
MMP_RS04205 +0.2 0.7 carboxymuconolactone decarboxylase family protein compare
MMP_RS05285 +0.2 1.0 MMPL family transporter compare
MMP_RS00645 +0.2 1.2 iron ABC transporter permease compare
MMP_RS05235 +0.2 1.1 exodeoxyribonuclease III compare
MMP_RS01860 +0.2 1.0 hypothetical protein compare
MMP_RS02970 +0.2 1.2 hypothetical protein compare
MMP_RS05695 +0.2 1.0 phospholipase D-like domain-containing protein compare
MMP_RS08775 +0.2 1.0 methanogenesis marker 9 domain-containing protein compare
MMP_RS05720 +0.1 0.9 signal recognition particle subunit SRP19/SEC65 family protein compare
MMP_RS05180 +0.1 1.1 Nre family DNA repair protein compare
MMP_RS01765 +0.1 1.0 HIT family protein compare
MMP_RS00125 +0.1 0.5 DUF2798 domain-containing protein compare
MMP_RS08555 +0.1 0.9 hypothetical protein compare
MMP_RS05810 +0.1 1.3 archaeosortase family protein ArtE compare
MMP_RS05580 +0.1 1.3 glycosyltransferase compare
MMP_RS01185 +0.1 0.7 hypothetical protein compare
MMP_RS06280 +0.1 1.2 alpha-glucan family phosphorylase compare
MMP_RS08630 +0.1 0.7 archaellar assembly protein FlaJ compare
MMP_RS03535 +0.1 0.6 helix-turn-helix transcriptional regulator compare
MMP_RS07800 +0.1 0.9 ATP-binding cassette domain-containing protein compare
MMP_RS05895 +0.1 1.2 metallophosphoesterase compare
MMP_RS01300 +0.1 1.2 hypothetical protein compare
MMP_RS02620 +0.1 1.2 DEAD/DEAH box helicase compare
MMP_RS02510 +0.1 1.1 site-specific integrase compare
MMP_RS01145 +0.1 1.2 ABC transporter ATP-binding protein compare
MMP_RS06655 +0.1 1.1 glycoside hydrolase family 15 protein compare
MMP_RS02690 +0.1 0.8 FmdE family protein compare
MMP_RS02775 +0.1 1.2 hypothetical protein compare
MMP_RS05280 +0.1 0.9 COG1361 S-layer family protein compare
MMP_RS00565 +0.1 0.8 CBS domain-containing protein compare
MMP_RS05960 +0.1 1.1 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS01605 +0.1 0.8 hypothetical protein compare
MMP_RS03875 +0.1 0.8 hypothetical protein compare
MMP_RS06430 +0.1 0.9 6-carboxytetrahydropterin synthase QueD compare
MMP_RS02255 +0.1 0.9 hypothetical protein compare
MMP_RS08275 +0.1 1.1 hypothetical protein compare
MMP_RS09060 +0.1 1.1 hypothetical protein compare
MMP_RS06535 +0.1 0.6 2-oxoacid:acceptor oxidoreductase family protein compare
MMP_RS05995 +0.1 1.1 FprA family A-type flavoprotein compare
MMP_RS08845 +0.1 1.0 archaellum operon transcriptional activator EarA family protein compare
MMP_RS04180 +0.1 1.1 iron-containing alcohol dehydrogenase compare
MMP_RS06305 +0.1 1.0 transporter substrate-binding domain-containing protein compare
MMP_RS00710 +0.1 0.9 hypothetical protein compare
MMP_RS06520 +0.1 0.8 DUF1786 domain-containing protein compare
MMP_RS05470 +0.1 1.1 DUF523 and DUF1722 domain-containing protein compare
MMP_RS08390 +0.1 0.7 DUF5400 domain-containing protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments

For nutrient t1 Nalidixic acid sodium salt across organisms